Clinical Trials Sponsored by Instituto Nacional de Saúde

Total 1990 results

ISAVE- Instituto Superior de Saúde

Recruiting

Validation of a Mobile App as an Adjuvant Treatment (VMA)

Validation

Portugal
Instituto Nacional de Saúde, Mozambique
World Health Organization

Completed

Comparison of Immunogenicity of Inactivated Poliovirus Vaccine (IPV) Administered Intramuscularly or Intradermally

Polio

Mozambique
Instituto Nacional de Saúde, Mozambique
M.D. Anderson Cancer Center

Not yet recruiting

Assessment of the Effectiveness of TA Versus LEEP for Cervical Cancer Risk Reduction in WLHIV in Mozambique

HIV Infections | HPV Infection | CIN 2/3

Mozambique
Centro de Investigação em Saúde de Manhiça
Imperial College London; World Health Organization; Barcelona Institute for Global... and other collaborators

Completed

COVID-19 Surveillance in Rural Mozambique for Prompt and Effective Response (MozCOVID)

COVID-19

Mozambique
Instituto Nacional de Saúde, Mozambique
Centers for Disease Control and Prevention

Completed

COVID-19 and HIV in Health Workers in Mozambique (COVIV)

Covid19 | Hiv

Mozambique
Bandim Health Project
Institudo Nacional de Saude Publica INASA

Completed

The Effect on Overall Mortality of a National Policy of Limiting Measles Vaccination to Children Below 12 Months of Age (MVEPI)

Mortality | Vaccines

Guinea-Bissau
Universidade do Porto
Unidade Local de Saúde de Matosinhos, EPE; Instituto de Saude Publica da Universidade... and other collaborators

Not yet recruiting

Improving the Referral of Patients With Suspected Cognitive Impairment and Early Dementia (DemRefImprov)

Cognitive Dysfunction | Mild Cognitive Impairment

Portugal
Linkoeping University
Escola Nacional de Saúde Pública - Universidade Nova de Lisboa

Unknown

A Guided Internet-delivered Individually-tailored ACT-influenced CBT Intervention to Improve Psychosocial Outcomes in Breast Cancer (INNOVBC)

Breast Neoplasm
Universidade do Porto
Instituto Portugues de Oncologia, Francisco Gentil, Porto; Unidade de Saúde... and other collaborators

Not yet recruiting

HPV Self-sampling for Women Who do Not Attend Cervical Cancer Screening Programme (HERSELF)

Papillomavirus Infections | Cervix Cancer | Early Detection of Cancer | Self-Examination
Foundation for Innovative New Diagnostics, Switzerland
Ludwig-Maximilians - University of Munich; Ifakara Health Institute; Centro de... and other collaborators

Active, not recruiting

TB-CAPT CORE Truenat Trial

Tuberculosis | Diagnoses Disease

Tanzania, Mozambique
Instituto Nacional de Saúde, Mozambique
UNITAID; Clinton Health Access Initiative Inc.; UNICEF

Completed

Early Infant Diagnosis Point of Care Pilot

HIV

Mozambique
University of Minho
Hospital de Braga; Administração Regional de Saúde do Norte, Portugal; Clinical... and other collaborators

Recruiting

Iodine Impact on Thyroid Function and Psychomotor Development, Observational Study in the Portuguese Minho Region (IodineMinho)

Pregnancy Related | Thyroid | Iodine Deficiency | Nutrient Deficiency | Psychomotor Impairment | Hypothyroidism in Pregnancy

Portugal
Universidade do Extremo Sul Catarinense - Unidade...
Conselho Nacional de Desenvolvimento Científico e Tecnológico; Hospital Universitário... and other collaborators

Recruiting

Intensive Self-care on Glycemic Control in Outpatients With Type 2 Diabetes Mellitus: The Diabetes Care (D-CARE) Study (D-CARE)

Cardiovascular Diseases | Diabetes Mellitus, Type 2 | Diabetes Mellitus

Brazil
Instituto de Saude Publica da Universidade do Porto

Recruiting

Multiple Interventions to Accelerate the Return to the Pre-event Level of Functioning After a TIA and Minor Stroke

Transient Ischemic Attack | Minor Stroke

Portugal
Instituto de Saude Publica da Universidade do Porto

Not yet recruiting

Experimental Study to Reduce Low Birthweight (STOP-LBW)

Infant, Low Birth Weight
Secretaria de Estado da Saúde
Instituto do Cancer do Estado de São Paulo

Terminated

Efficacy and Safety of Synthetic Phosphoethanolamine in Solid Tumor Patients

Solid Tumor

Brazil
Instituto de Saude Publica da Universidade do Porto

Recruiting

MIND-Matosinhos: Multiple Interventions to Prevent Cognitive Decline

Neurocognitive Disorders | Cognitive Impairment | Cognitive Dysfunction | Memory Disorders | Cognition Disorder

Portugal
Instituto Politécnico de Bragança
European Social Fund; Unidade Local de Saúde do Nordeste

Enrolling by invitation

Prediabetes Intervention With Tea (PREVENT)

Diabetes Mellitus, Type 2 | Pre Diabetes

Portugal
Michael Hoelscher
University of Liverpool; National Institute for Medical Research (NIMR) - Mbeya... and other collaborators

Not yet recruiting

Increasing Neonatal HIV Test and Treat to Maximize the Long-Term Impact on Infant Health and Novel Infant Antiretroviral Treatment (LIFE2Scale)

Infant, Newborn, Diseases | Infant Death | Infant Morbidity | Vertical Human Immunodeficiency Virus Transmission | HIV Infection Pediatric

Mozambique, Tanzania
National Institute of Cancerología
Instituto Nacional de Rehabilitacion

Completed

Use of Clorhexidine Dressings to Reduce Surgical Site Infections in Breast Cancer Surgery. A Controlled Clinical Trial

Breast Cancer

Mexico
Instituto Materno Infantil Prof. Fernando Figueira
Universidade Federal do Ceará; Instituto de Saúde Elpidio de Almeida

Completed

Oral Titrated Misoprostol for Induction of Labour (OTISMISO)

Labor, Induced

Brazil
Universidade Lusófona de Humanidades e Tecnologias
Casa de Saúde do Telhal - Instituto São João de Deus, Portugal.

Active, not recruiting

Virtual Reality Cognitive Training in Alcohol Use Disorder

Feasibility | Cognitive Function

Portugal
Centro de Investigação em Saúde de Manhiça
Barcelona Institute for Global Health

Completed

Mass Drug Administrations of DHA-PQP to Accelerate Towards Malaria Elimination in Magude District, Southern Mozambique (MDAM)

Malaria
Instituto Nacional de Cancerologia, Columbia

Unknown

Trastuzumab or Observation After Combination Chemotherapy and Trastuzumab in Treating Patients Undergoing Surgery for Stage II or Stage III Breast Cancer

Breast Cancer

Mexico
National Institute of Cancerología
Instituto Nacional de Enfermedades Respiratorias

Completed

Impact of Valganciclovir on Severe IRIS-Kaposi Sarcoma Mortality: an Open-label, Parallel, Randomized Controlled-trial.

Kaposi Sarcoma | Human Immunodeficiency Virus | Immune Reconstitution Syndrome

Mexico
Institute of Tropical Medicine, Belgium
UMC Utrecht; European and Developing Countries Clinical Trials Partnership... and other collaborators

Completed

Characterising Transmission of SARS-CoV-2 in a Peri-urban Population in Mozambique (AfriCoVER)

COVID-19

Mozambique
National Institute of Cancerología
Instituto Nacional de Enfermedades Respiratorias

Completed

K-RAS Oncogene Mutation in Patients With Advanced Non-Small Cell Lung Cancer Associated With Exposure to Wood Smoke and Tobacco Smoking: Therapeutic Implications (007/055/OMI)

Non-Small Cell Lung Cancer

Mexico
National Institute of Cancerología
Instituto Nacional de Enfermedades Respiratorias

Completed

Effect of All-trans Retinoic Acid With Chemotherapy Based in Paclitaxel and Cisplatin as First Line Treatment of Patients With Advanced Non-small Cell Lung Cancer

Non-Small-Cell Lung Carcinoma

Mexico
University of Évora
Universidade Nova de Lisboa; Comprehensive Health Research Centre; Unidade Local... and other collaborators

Recruiting

Effects of Vitamin D on Health Promotion During Pregnancy and Its Impact on Prematurity-Related Outcome (VitDTracking)

Vitamin D Deficiency | Pregnancy

Portugal
Eduardo Mondlane University
National Heart, Lung, and Blood Institute (NHLBI); University of Washington; Instituto... and other collaborators

Recruiting

Expanding Health Systems Research to Optimize Hypertension Care Cascade in HIV-Infected Individuals in Mozambique (SCALESAIAHTN)

Hypertension

Mozambique
Instituto Nacional de Saúde, Mozambique
European and Developing Countries Clinical Trials Partnership (EDCTP); Swedish...

Completed

Safety and Immunogenicity Study of a DNA Priming and MVA Boosting Strategy of HIV Vaccine

HIV Infections

Mozambique
Instituto Nacional de Cancer, Brazil
Instituto Nacional de Cardiologia de Laranjeiras

Unknown

Health Outcomes and Costs (HOC) in Lung Cancer (LC) (HOC-LC)

Lung Cancer

Brazil
Instituto Nacional de Cancerologia de Mexico
Instituto Nacional de Enfermedades Respiratorias

Recruiting

Prophylactic Inhaled Steroids to Reduce Radiation Pneumonitis Frequency and Severity in Lung Cancer Patients

Radiation Pneumonitis

Mexico
Instituto Nacional de Perinatologia Isidro Espinosa...
National Polytechnic Institute, Mexico

Not yet recruiting

Effect of Cocoa Polyphenols Supplementation on Cardiovascular Risk of Postmenopausal Women

Metabolic Syndrome

Mexico
Foundation for Innovative New Diagnostics, Switzerland
Ludwig-Maximilians - University of Munich; Heidelberg University; Swiss Tropical... and other collaborators

Recruiting

TB-CAPT EXULTANT - HIV

Tuberculosis | Diagnoses Disease | HIV Coinfection

Mozambique, Tanzania
PATH
Tulane University; Liverpool School of Tropical Medicine; Ministry of Health,... and other collaborators

Completed

Estimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generated During Piloted New Net Distributions in Mozambique

Malaria

Mozambique
Aveiro University
Fundação para a Ciência e a Tecnologia; Centro Hospitalar do Baixo Vouga; Administração... and other collaborators

Completed

PICk-UP: PersonalIsed CommUnity-based Physical Activities for Patients With Chronic Obstructive Pulmonary Disease (PICk UP)

COPD

Portugal
Instituto Nacional de Cardiologia Ignacio Chavez
Instituto Nacional de Rehabilitacion

Unknown

Effects of Allopurinol on Inflammation and Ultrasonographic Changes in People With Elevated Uric Acid But no Symptoms

Inflammation | Hyperuricemia | Musculoskeletal Degeneration

Mexico
Universidade Federal do Rio de Janeiro
National Research Council, Brazil; Ministry of Science and Technology, Brazil; ATCG... and other collaborators

Completed

Effects of Early Use of Nitazoxanide in Patients With COVID-19

Covid19 | Coronavirus

Brazil
London School of Hygiene and Tropical Medicine
Centers for Disease Control and Prevention; Georgia Institute of Technology; Instituto...

Recruiting

SaniVac Trial - Sanitation and Oral Rotavirus Vaccine Performance

Environmental Enteric Dysfunction | Rotavirus Infections | Enteric Infections

Mozambique
Instituto Nacional de Cancerologia de Mexico

Recruiting

Glutamine Plus L. Reuteri Prevents TKI Therapy-diarrhea in Patients With NSCLC

Non-Small Cell Lung Cancer With EGFR Mutation

Mexico
Instituto Nacional de Cancerologia de Mexico

Completed

Ketamine or Placebo in Patients With Major Depression and Advanced Cancer (KODIAC)

Major Depressive Disorder | Advanced Cancer

Mexico
Instituto Nacional de Cancerologia de Mexico

Completed

Tetracycline as a Prophylaxis for Rash in Patients With NSCLC Receiving Treatment With BIBW2992 (Afatinib)

Lung Cancer | Skin Rash

Mexico
Instituto Nacional de Cancerologia de Mexico

Unknown

Effectiveness and Quality of Life Analysis of Palonosetron Against Ondansetron Combined With Dexamethasone and Fosaprepitant in Prevention of Acute and Delayed Emesis Associated to Chemotherapy Moderate and Highly Emetogenic in Breast Cancer.

Quality of Life | Breast Neoplasm | Antineoplastic Agents | Antiemetics

Mexico
Instituto Nacional de Cancerologia de Mexico

Unknown

ALK Rearrangements in Lung Adenocarcinoma: Epidemiology in Latin America (CLICaP)

Lung Cancer

Mexico
Instituto Nacional de Cancerologia de Mexico

Completed

Early Incorporation of Patient and Family to Attention and Care Program in Oncology Versus Standard of Care (PACO)

Lung Neoplasms

Mexico
Instituto Nacional de Cancerologia de Mexico

Unknown

Nabilone Effect on the Attenuation of Anorexia, Nutritional Status and Quality of Life in Lung Cancer Patients

Anorexia | Non-Small Cell Lung Cancer | Cachexia | Weight Lose

Mexico
Instituto Nacional de Cardiologia de Laranjeiras

Recruiting

Cerebral Oxygen Saturation Monitoring In Cardiac Surgery (COSMICS) (COSMICS)

Cognitive Dysfunction | Cardiac Disease

Brazil
Instituto Nacional de Cancerologia de Mexico

Completed

Treatment With BIBW 2992, Irreversible Inhibitor of EGFR and HER-2 in Non-small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer | EGFR | HER-2

Mexico
Instituto Nacional de Cancerologia de Mexico

Completed

Radical Treatment of Synchronous Oligometastatic Non-Small Cell Lung Carcinoma

Carcinoma, Non-Small-Cell Lung | Synchronous Neoplasms

Mexico

Clinical Trials Sponsored by Instituto Nacional de Saúde

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