Clinical Trials Sponsored by Ioltech

Total 1581 results

BioNTech US Inc.

Recruiting

NEO-PTC-01 in Patients With Advanced or Metastatic Melanoma

Metastatic Melanoma | Unresectable Melanoma

Belgium, Netherlands, Spain
Assistance Publique - Hôpitaux de Paris
Ioltech

Terminated

CLAIR -FO: Clinical Trial of Ophthalmic Insert Mydriasert® Versus Reference Treatment

Premature Birth | Retinal Anomalies

France
Sotio Biotech Inc.
SOTIO Biotech AG; SOTIO Biotech a.s.

Recruiting

BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors (DUET-1)

Hepatocellular Carcinoma | Squamous Cell Carcinoma of the Lung | Merkel Cell Carcinoma | Myxoid/Round Cell Liposarcoma

United States
SOTIO Biotech AG
SOTIO Biotech a.s.

Active, not recruiting

Study of SO-C101 and SO-C101 in Combination With Pembro in Adult Patients With Advanced/Metastatic Solid Tumors

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Gastric Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Mesothelioma | Bladder Cancer | Triple Negative Breast Cancer | Small-cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Thyroid | Anal Cancer | Merkel Cell Carcinoma | Biliary... and other conditions

United States, France, Spain, Czechia
BioNTech Research & Development, Inc.

Recruiting

Study of HuMab-5B1 (MVT-5873) in Subjects With Pancreatic Cancer or Other Cancer Antigen 19-9 (CA19-9) Positive Malignancies

Pancreatic Cancer

United States
BioNTech RNA Pharmaceuticals GmbH

Completed

RBL001/RBL002 Phase I Clinical Trial (MERIT)

Melanoma

Austria, Germany
Neovii Biotech
Fresenius Biotech North America

Completed

Safety and Efficacy Study of Catumaxomab to Treat Ovarian Cancer After a Complete Response to Chemotherapy

Ovarian Cancer

United States
Neovii Biotech
Fresenius Biotech North America

Terminated

Phase II Study With the Trifunctional Antibody Ertumaxomab to Treat Metastatic Breast Cancer After Progression on Trastuzumab Therapy

Advanced Breast Cancer | Metastatic Breast Cancer

United States, Canada
Impact Biotech Ltd
Impact biotech Ltd.

Not yet recruiting

Padeliporfin VTP Using Robotic Assisted Bronchoscopy in Peripheral Lung Cancer

Peripheral Lung Tumor
BioNTech Research & Development, Inc.

Terminated

Study of 177Lu Human Monoclonal Antibody 5B1 (MVT-1075) in Combination With a Blocking Dose of MVT-5873 as Radioimmunotherapy

Pancreatic Carcinoma | Tumors That Express CA 19-9

United States
J2H Biotech

Recruiting

Phase 2a Study to Evaluate Safety and Explore Efficacy of J2H-1702 for NASH

Non-alcoholic Steatohepatitis

Korea, Republic of
Essen Biotech

Not yet recruiting

Fourth-gen CAR T Cells Targeting CD19/CD22 for Highly Resistant B-cell Lymphoma/Leukemia (PMBCL/CNS-BCL). (BAH241)

Lymphoma, Follicular | Diffuse Large B Cell Lymphoma | Acute Lymphoblastic Leukemia, in Relapse | MCL | Central Nervous System Lymphoma | Acute Lymphoblastic Leukemia, Adult B-Cell | Non-Hodgkin Lymphoma, B-cell

China
Meccellis Biotech

Recruiting

Evaluation of a Non-cross-linked Porcine Acellular Dermal Matrix Used in Dental Surgery

Dental Surgery

France
BioNTech SE

Recruiting

A Clinical Trial in Healthy Volunteers to Study the Safety, Tolerability, and Immune Responses After Vaccination With an Investigational Vaccine Designed to Prevent Genital Herpes Lesions

Genital Herpes Simplex Type 2

United States
BioNTech SE

Recruiting

Safety and Preliminary Efficacy Trial of BNT142 in Patients With CLDN6-positive Solid Tumors

Solid Tumor

United States, Spain, Singapore, United Kingdom
HoHo Biotech

Recruiting

To Evaluate the Safety of Treating Rheumatologic and Metabolic Patients With Molecular Hydrogen Supplement.

Autoimmune Diseases | Metabolic Disease

Taiwan
BioNTech SE

Recruiting

Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer (LuCa-MERIT-1)

Non-Small Cell Lung Cancer

Spain, Germany, Turkey, United States, Hungary, United Kingdom, Poland
BioNTech SE

Recruiting

Dose Escalation Trial of BNT152+153 in Patients With Cancer

Solid Tumor

United States, Czechia
BioNTech SE

Active, not recruiting

Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT411

Solid Tumor | Extensive-stage Small Cell Lung Cancer

United States, Spain, United Kingdom, Germany
BioNTech SE

Active, not recruiting

Safety and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria

Malaria

United States
BioNTech SE

Terminated

PRO-MERIT (Prostate Cancer Messenger RNA Immunotherapy) (PRO-MERIT)

Prostate Cancer

United States, Germany, United Kingdom, Hungary
CoolTech LLC

Terminated

Transnasal Cooling for Migraine

Migraine | Migraine Without Aura | Migraine With Aura | Episodic Migraine

United States
CoolTech LLC

Completed

Transnasal Induction of Normothermia in Febrile Stroke Patients

Fever | Seizures | Stroke, Ischemic | Stroke Hemorrhagic | Metabolic Encephalopathy

United States
BioNTech SE

Completed

A Trial Investigating the Safety and Effects of One or Two Additional Doses of Comirnaty or One Dose of BNT162b2s01 in BNT162-01 or BNT162-04 Trial Subjects

COVID-19 | SARS-CoV-2 Infection

Germany
Acticor Biotech

Completed

Glenzocimab in SARS-Cov-2 Acute Respiratory DistrEss syNdrome Related to COVID-19 (GARDEN)

COVID-19 | Acute Respiratory Distress Syndrome | ARDS | SARS-CoV Infection

France
Neovii Biotech

Completed

Study of US-ATG-F to Prevent Chronic Graft Versus Host Disease (GVHD)

Myelodysplastic Syndrome | GVHD | Adult Acute Myeloid Leukemia | Adult Acute Lymphoid Leukemia

United States, Australia
Iantech, Inc

Unknown

A Study to Assess the Clinical Outcomes of Surgical Phaco Segmentation Techniques in Patients Undergoing Cataract Surgery

Cataract

Panama
Activartis Biotech

Completed

Dendritic Cell Cancer Vaccine for High-grade Glioma (GBM-Vax)

Glioblastoma Multiforme

Austria
Trinity Biotech

Unknown

Clinical Study to Validate the Use of a New Point of Care Troponin I Test

Acute Coronary Syndrome

United States
Oncolytics Biotech

Completed

Phase 2 Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Patients With Head and Neck Carcinoma

Carcinoma, Squamous Cell of the Head and Neck

United States
Oncolytics Biotech

Completed

Safety and Efficacy Study of REOLYSIN® in the Treatment of Recurrent Malignant Gliomas

Malignant Glioma

United States
Neovii Biotech

Completed

Safety Study of Second Intraperitoneal (I.P.) Infusion Cycle of Catumaxomab in Patients With Malignant Ascites (SECIMAS)

Malignant Ascites Due to Epithelial Carcinoma

Germany
Facet Biotech

Withdrawn

A Randomized, Double-blinded, Placebo-controlled, Dose-ranging Study of Cardene® I.V. in Pediatric Subjects With Hypertension

Hypertension

United States
Facet Biotech

Completed

Research Study of Visilizumab for Treatment of Acute Graft Versus Host Disease

Graft vs Host Disease

United States
Facet Biotech

Completed

Research Study in Patients With Severe Ulcerative Colitis

Ulcerative Colitis

United States
Facet Biotech

Withdrawn

A Study of Ularitide in the Treatment of Subjects With Acute Decompensated Heart Failure

Heart Failure, Congestive

United States
Neovii Biotech

Terminated

Phase II Study With the Trifunctional Antibody Ertumaxomab to Treat Metastatic Breast Cancer Progressing After Endocrine Treatment

Advanced Breast Cancer | Metastatic Breast Cancer

Spain, Austria, France, Germany, Italy
Neovii Biotech

Completed

Safety and Efficacy Study With Catumaxomab in Patients After Curative Resection of a Gastric Adenocarcinoma

Gastric Cancer | Gastric Adenocarcinoma

Germany
Global Biotech

Completed

Safety Study of a Recombinant Human Plasminogen Activator to Treat Acute Ischemic Stroke.

Cerebrovascular Accident

Taiwan
BioNTech SE

Recruiting

Safety, Tolerability, and Efficacy of mFOLFIRINOX ± BNT321 as Adjuvant Therapy Following Curative Resection in Patients With Pancreatic Adenocarcinoma

Pancreatic Cancer

United States
Aurion Biotech

Recruiting

A Phase 1/2 Study of AURN001 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction (ABA-1) (CLARA)

Corneal Edema | Corneal Endothelial Dysfunction

United States, Canada
BioNTech SE

Recruiting

A Clinical Study Investigating the Safety and Immune Responses After Immunization With Investigational Monkeypox Vaccines

Monkeypox

United Kingdom, United States
Momtech Inc.

Recruiting

Engineering Evaluation of a Breast Pump Device

Healthy | Breast Pumping

United States
Meccellis Biotech

Recruiting

Safety and Clinical Performance of a Biological Matrix Used in Implant-based Breast Reconstruction

Breast Reconstruction Following Mastectomy

France
BioNTech SE

Recruiting

Epidemiological Study to Monitor Study Participants With Resected Stage II (High Risk) or Stage III Colorectal Cancer for Circulating Tumor DNA Before, During and After Their Treatment With Adjuvant Chemotherapy

Colorectal Cancer Stage II | Colorectal Cancer Stage III

United States, Spain, Germany, Belgium
ElsaLys Biotech

Not yet recruiting

Evaluation of EFficacy and SaFEty of Leukotac (Inolimomab) in Pediatric Patients With SR-aGvHD (EiFFEL)

Steroid Refractory GVHD
BioNTech SE

Active, not recruiting

BNT151 as a Monotherapy and in Combination With Other Anti-cancer Agents in Patients With Solid Tumors

Solid Tumor

United States, Spain
J2H Biotech

Completed

Phase 1 Study to Investigate Safety, Tolerability, PK/PK of J2H-1702 in Healthy Males

Non-alcoholic Steatohepatitis

Korea, Republic of
CEN Biotech

Completed

Effect of Audistim® Day/Night on Hearing Comfort and Patient Quality of Life of Patients With Chronic Tinnitus. (TINNITY)

Tinnitus

France
Aurion Biotech

Completed

A Safety and Efficacy Study of Corneal Injection for Endothelial Dysfunction Using Human Corneal Endothelial Cell Therapy in Subjects With Corneal Edema Secondary to Endothelial Dysfunction (Escalon)

Corneal Edema

El Salvador

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