Clinical Trials Sponsored by Istituto Di Ricerche Farmacologiche Mario Negri

Total 50 results

Antea Foundation
Istituto Di Ricerche Farmacologiche Mario Negri

Recruiting

Evaluation of ESMO Guidelines Applicability and Adherence in Cancer Pain Management in the Palliative Care Setting

Pain | Cancer | Cancer Pain

Italy
Istituto Clinico Humanitas
Istituto Di Ricerche Farmacologiche Mario Negri

Completed

Aging of Hematopoietic Stem Cells - Molecular Architecture of Marrow Dysplasia and Clinical Contribution of Ineffective Hematopoiesis to Frailty in the Elderly

Anemia | Clonal Hematopoiesis

Italy
Italian Sarcoma Group
Istituto Di Ricerche Farmacologiche Mario Negri

Completed

Efficacy Study on Trabectedin in Retroperitoneal Leiomyosarcoma and Well Differentiated/Dedifferentiated Liposarcoma (TRAVELL)

Leiomyosarcoma | Liposarcoma

Italy
University of Turin, Italy
Istituto Di Ricerche Farmacologiche Mario Negri

Not yet recruiting

Preventing Cardiovascular Collapse With Vasopressors During Tracheal Intubation (PREVENTION)

Critical Illness | Respiratory Failure

France, Ireland, Italy
Italian Sarcoma Group
AstraZeneca; PharmaMar; Istituto Di Ricerche Farmacologiche Mario Negri

Completed

Trabectedin Plus Olaparib in Metastatic or Advanced Sarcomas (TOMAS) (TOMAS)

Soft Tissue Sarcoma | Bone Tumor

Italy
Fondazione Don Carlo Gnocchi Onlus
Istituto Di Ricerche Farmacologiche Mario Negri

Completed

Efficacy Study of FES Controlled by Electromyographic Signal for the Treatment of Upper Limb in Post-stroke Patients (RiSES)

Stroke
Fondazione I.R.C.C.S. Istituto Neurologico Carlo...
Istituto Di Ricerche Farmacologiche Mario Negri

Recruiting

Clinical Study to Monitor Plasma Levels of 24OHC in Subject With HD (Chol-HD)

Huntington Disease

Italy
IRCCS Sacro Cuore Don Calabria di Negrar
Istituto Di Ricerche Farmacologiche Mario Negri

Terminated

COVidIVERmectin: Ivermectin for Treatment of Covid-19 (COVER)

Covid19

Italy
Fondazione IRCCS Istituto Nazionale dei Tumori,...
Istituto Di Ricerche Farmacologiche Mario Negri

Active, not recruiting

Screening and Multiple Intervention on Lung Epidemics (SMILE)

Smoking Cessation | Inflammation | Physical Activity | Lung Cancer | Diet Modification

Italy
Fondazione IRCCS Policlinico San Matteo di Pavia
Istituto di Ricerche Farmacologiche Mario Negri IRCCS

Recruiting

The Italian Registry of Malnutrition in Oncology (IRMO)

Cancer | Cancer Metastatic

Italy
Monia Lorini
Istituto Di Ricerche Farmacologiche Mario Negri

Unknown

ACE-inhibitors in Extracapillary Glomerulonephritis (EXTRA)

Extracapillary Glomerulonephritis

Italy
Ente Ospedaliero Ospedali Galliera
Istituto Di Ricerche Farmacologiche Mario Negri; Humanitas Hospital, Italy

Recruiting

Letrozole for Estrogen/Progesterone Receptor Positive Low-grade Serous Epithelial Ovarian Cancer (LEPRE Trial) (LEPRE)

Carcinoma, Ovarian Epithelial | Low Grade Serous Adenocarcinoma of Ovary

Italy
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
Istituto Di Ricerche Farmacologiche Mario Negri

Recruiting

ALBumin Italian Outcome Septic Shock-BALANCED Trial (ALBIOSS-BALANCED) (ALBIOSS-BAL)

Septic Shock

Italy
Fondazione Policlinico Universitario Agostino Gemelli...
Istituto Di Ricerche Farmacologiche Mario Negri; Foundation Medicine

Recruiting

Carboplatin-Paclitaxel-Bevacizumab vs Carbo-Pacli-Beva-Rucaparib vs Carbo-Pacli-Ruca, Selected According to HRD Status, in Patients With Advanced Ovarian, Primary Peritoneal and Fallopian Tube Cancer, Preceded by a Phase I Dose Escalation Study on Ruca-Beva Combination (MITO25)

Advanced (Stage IIIB-C-IV) Ovarian, Primary Peritoneal and Fallopian Tube Cancer

Italy
Myway Gentics Srl
Istituto Di Ricerche Farmacologiche Mario Negri; Fondazione IRCCS Policlinico...

Unknown

Non-invasive Test for Acute Rejection Identification in Heart Transplanted Patients (INNOGRAFTRS001)

Acute Rejection of Cardiac Transplant

Italy
IRCCS Centro San Giovanni di Dio Fatebenefratelli
Ospedale San Raffaele; Istituto Di Ricerche Farmacologiche Mario Negri

Completed

EMuNI Project: Multiple Nonpharmacological Interventions (EMuNI)

Lifestyle Risk Reduction

Italy
Fondazione IRCCS Istituto Nazionale dei Tumori,...
Istituto Di Ricerche Farmacologiche Mario Negri; Gruppo Oncologico del Nord-Ovest

Recruiting

Improving Outcome of Selected Patients With Non-resectable Hepatic Metastases From Colo-rectal Cancer With Liver Transplantation (COLT)

Neoplasms | Colorectal Cancer Metastatic | Liver Metastases | Liver Neoplasm

Italy
Niguarda Hospital
Istituto Di Ricerche Farmacologiche Mario Negri; Ministry of Health, Italy; University... and other collaborators

Recruiting

MYTHS - MYocarditis THerapy With Steroids (MYTHS)

Myocarditis Acute

Italy, United States, Spain, Belgium, Slovenia, Finland, France, Sweden, Czechia, Denmark, Germany, Greece
Azienda Unità Sanitaria Locale Reggio Emilia
Istituto Di Ricerche Farmacologiche Mario Negri; Istituto Nazionale Tumori...

Recruiting

Study in mCRC Patients RAS/BRAF wt Tissue and RAS Mutated LIquid BIopsy to Compare FOLFIRI Plus CetuxiMAb or BevacizumaB (LIBImAb)

Metastatic Colorectal Cancer | Colorectal Cancer | RAS Mutation

Italy
Mario Negri Institute for Pharmacological Research
Istituto Superiore di Sanità

Completed

Effects of Caloric Restriction in Obesity and Type 2 Diabetes (CRESO2)

Obesity | Type 2 Diabetes

Italy
Istituti Ospitalieri di Cremona
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano; Centro di Riferimento... and other collaborators

Completed

A Stepped Wedge Cluster Randomized Controlled Trial to Assess a Strategy Aiming to Optimize Psychosocial Outcomes in Patients With Cancer (HuCare2)

Cancer

Italy
Mario Negri Institute for Pharmacological Research
Istituto Superiore di Sanità

Completed

Preventing Renal Functional Abnormalities With Calorie Restriction in Subjects With Abdominal Obesity and Type 2 Diabetes at Increased Renal and Cardiovascular Risk (CRESO)

Diabetes Mellitus

Italy
Ente Ospedaliero Ospedali Galliera
Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Istituto Di Ricerche... and other collaborators

Terminated

Exemestane in Hormone Receptor Positive High Grade Ovarian Cancer (EXPERT)

Ovarian Cancer

Italy
Imperial College London
University College, London; Centre Hospitalier Universitaire Vaudois; Fondazione... and other collaborators

Completed

Developing and Validating Blood and Imaging BIOmarkers of AXonal Injury Following Traumatic Brain Injury (BIO-AX-TBI)

Traumatic Brain Injury

Switzerland, United Kingdom, Italy, Slovenia
Istituto Clinico Humanitas
University of Turin, Italy; Universita degli Studi di Genova; Istituto Di Ricerche... and other collaborators

Completed

Rituximab in Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDPRIT)

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Italy
Fondazione IRCCS San Gerardo dei Tintori
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico; A.O. Ospedale Papa... and other collaborators

Recruiting

Mesenchymal Stromal Cells for Traumatic Brain Injury (MATRIx)

Traumatic Brain Injury With Loss of Consciousness

Italy
University of Milano Bicocca
University of Roma La Sapienza; Istituto Di Ricerche Farmacologiche Mario Negri and other collaborators

Recruiting

Clinical Trial on Remote Ischemic Conditioning in Acute Ischemic Stroke Within 9 Hours of Onset in Patients Ineligible to Recanalization Therapies (TRICS-9)

Ischemic Stroke

Italy
Mario Negri Institute for Pharmacological Research
Fondazione IRCCS Policlinico San Matteo di Pavia

Completed

Pulsed Perfusion for Marginal Kidneys (PREDICTION)

Chronic Kidney Disease

Italy
Mario Negri Institute for Pharmacological Research
Associazione Italiana per la Ricerca sul Cancro

Completed

Neoadjuvant Zoledronate and Atorvastatin in Triple Negative Breast Cancer (YAPPETIZER)

Triple Negative Breast Cancer

Italy
Mario Negri Institute for Pharmacological Research
Associazione Italiana per la Ricerca sul Cancro

Terminated

Pre-operative Zoledronate in Triple Negative Breast Cancer

Breast Cancer

Italy
Mario Negri Institute for Pharmacological Research
Ministry of Health, Italy; Azienda Ospedaliera San Gerardo di Monza

Active, not recruiting

Low vs. Standard Daily Doses of Antiepileptic Drugs in Newly Diagnosed, Previously Untreated Epilepsy(STANDLOW) (STANDLOW)

Epilepsies, Partial

Italy
Mario Negri Institute for Pharmacological Research
Belfast Health and Social Care Trust; National University of Ireland, Galway... and other collaborators

Active, not recruiting

NEPHSTROM for Diabetic Kidney Disease (NEPHSTROM)

Diabetic Kidney Disease

Ireland, Italy, United Kingdom
University of Milano Bicocca
Azienda Ospedaliera Universitaria Integrata Verona; Azienda Socio Sanitaria... and other collaborators

Recruiting

Dual Anti-glutamate Therapy in Super-refractory Status Epilepticus After Cardiac Arrest (SUPER-CAT)

Cardiac Arrest | Status Epilepticus

Italy
Azienda Ospedaliero-Universitaria di Modena
IRCCS San Raffaele; Catholic University of the Sacred Heart; University of Padova and other collaborators

Completed

Colchicine for Amyotrophic Lateral Sclerosis (Co-ALS)

Amyotrophic Lateral Sclerosis

Italy
Ospedale Santa Croce-Carle Cuneo
Azienda Ospedaliera di Padova; S. Andrea Hospital; San Giuseppe Moscati Hospital and other collaborators

Unknown

Italian Absorb Registry (BVS-RAI)

Coronary Artery Disease

Italy
Wroclaw Medical University
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico; University of Valencia and other collaborators

Unknown

FOCUS- Frailty Management Optimization Through EIP AHA Commitments and Utilization of Stakeholders Input (FOCUS-WMU)

Frailty

Poland
Fundación Centro Nacional de Investigaciones Cardiovasculares...
London School of Hygiene and Tropical Medicine; Ferrer Internacional S.A.; Charite... and other collaborators

Completed

Secondary Prevention of Cardiovascular Disease in the Elderly Trial (SECURE)

Myocardial Infarction | Cardiovascular Disease

Spain, Germany, France, Czechia, Hungary, Italy, Poland
Centro Cardiologico Monzino
Fondazione Policlinico Universitario Agostino Gemelli IRCCS; IRCCS Policlinico... and other collaborators

Active, not recruiting

Italian Digital Primary Cardiovascular Prevention Study (CV-PREVITAL)

Healthy Population

Italy
Prof Brian Lawlor
King's College London; Göteborg University; University College Dublin; Aristotle... and other collaborators

Completed

A Phase III Trial of Nilvadipine to Treat Alzheimer's Disease (NILVAD)

Alzheimer's Disease

Germany, Ireland, United Kingdom, France, Greece, Hungary, Italy, Netherlands, Sweden
IRCSS Istituto Dermopatico dell'Immacolata, Fondazione...
Ministry of Health, Italy; Centro di Eccellenza per la Cultura e la Ricerca...

Completed

A Comparison Between Two Educational Methods in the Rehabilitation of the Microstomia in Systemic Sclerosis (SScM398-1)

Scleroderma, Systemic
Fondazione Policlinico Universitario Agostino Gemelli...
IRCCS Azienda Ospedaliero-Universitaria di Bologna; Fondazione I.R.C.C.S. Istituto... and other collaborators

Not yet recruiting

National Database of the Virtual Institute of Cerebrovascular Diseases (BIG-MENTI)

Cerebrovascular Disease

Italy
IRCCS National Neurological Institute "C. Mondino...
IRCCS Associazione Oasi Maria SS. ONLUS, Troina, Italy; IRCCS Istituto Auxologico... and other collaborators

Completed

Validation of the I-UDS Neuropsychological Battery

Alzheimer Disease | Mild Cognitive Impairment

Italy
Mario Negri Institute for Pharmacological Research
Aventis Pharmaceuticals; Istituto Scientifico Romagnolo per lo Studio e la... and other collaborators

Completed

Intergroup Trial of Adjuvant Chemotherapy in Adenocarcinoma of the Stomach (ITACA-S)

Adenocarcinoma of the Gastroesophageal Junction | Adenocarcinoma of the Stomach

Italy
Peter Rossing
University Medical Center Groningen; European Commission; Istituto Di Ricerche... and other collaborators

Completed

Proteomic Prediction and Renin Angiotensin Aldosterone System Inhibition Prevention Of Early Diabetic nephRopathy In TYpe 2 Diabetic Patients With Normoalbuminuria (PRIORITY)

Diabetic Retinopathy | Diabetic Nephropathy

Netherlands, Belgium, Spain, Czechia, Germany, United Kingdom, Denmark, Greece, Italy, Macedonia, The Former Yugoslav Republic of
IRCCS San Raffaele
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano; Regina Elena Cancer... and other collaborators

Active, not recruiting

Longitudinal Evaluation of Intestinal, Haematological and Urinary Toxicity From Pelvic Irradiation for Prostate Cancer (IHU-WPRT-TOX)

Prostate Cancer

Italy
IRCCS Azienda Ospedaliera Universitaria San Martino...
Azienda Ospedaliera Universitaria Integrata Verona; Azienda Ospedaliera San... and other collaborators

Unknown

Customized Neoadjuvant Versus Standard Chemotherapy in NSCL Patients With Resectable Stage IIIA (N2)Disease (CONTEST)

Non Small Cell Lung Cancer

Italy
Institut National de la Santé Et de la Recherche...
Assistance Publique - Hôpitaux de Paris; Cardiff University; Karolinska Institutet and other collaborators

Withdrawn

TINN2: Treat Infection in NeoNates 2 (TINN2)

Bronchopulmonary Dysplasia

Belgium, France, Germany, Hungary, Italy, Luxembourg, Netherlands, Sweden, United Kingdom
University of Cagliari
Chiara Gerardi - Istituto Di Ricerche Farmacologiche Mario Negri; Federico... and other collaborators

Recruiting

coMpliAnce With evideNce-based cliniCal Guidelines in the managemenT of Acute biliaRy pancreAtitis (MANCTRA-1)

Covid19 | Acute Pancreatitis | Acute Pancreatic Necrosis | Acute Pancreatic Fluid Collection | Acute Pancreatitis Without Necrosis or Infection | Acute Pancreatitis Due to Gallstones | Acute Pancreatitis With Infected Necrosis | Acute Pancreatitis Due to Common Bile Duct Calculus | Acute Pancreatitis... and other conditions

Italy, Spain
IRCCS Azienda Ospedaliera Universitaria San Martino...
Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Azienda Ospedaliera... and other collaborators

Unknown

Multicentric Prospective Randomized Trial on Surgery Versus Standard Medical Care in Type 2 Diabetic Patients BMI 30-35 (DIA-CHIR-MULT)

Diabetes Mellitus

Italy
University of Siena
Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Istituti Ospitalieri... and other collaborators

Recruiting

Genetic Bases of COVID-19 Clinical Variability (GEN-COVID)

COVID-19

Italy

Clinical Trials Sponsored by Istituto Di Ricerche Farmacologiche Mario Negri

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