Clinical Trials Sponsored by Jacobus Pharmaceutical

Total 19564 results

Jacobus Pharmaceutical

Completed

Effectiveness of 3,4-Diaminopyridine in Lambert-Eaton Myasthenic Syndrome (DAPPER)

Lambert-Eaton Myasthenic Syndrome | Eaton-Lambert Myasthenic Syndrome

United States
Jacobus Pharmaceutical

Terminated

High Dose Oral 4-Aminosalicylic Acid (PASER®) to Control Acute Flares of Mild to Moderate Crohn's Disease

Crohn's Disease

United States, Israel
Jacobus Pharmaceutical

Terminated

High Dose Oral 4-Aminosalicylic Acid (PASER®) to Control Acute Flares of Mild to Moderate Crohn's Disease in Children

Crohn's Disease

United States
Jacobus Pharmaceutical

Terminated

Efficacy of Dapsone as a Steroid Sparing Agent in Pemphigus Vulgaris

Pemphigus Vulgaris

United States
Oregon Health and Science University
Jacobus Pharmaceutical

No longer available

3,4-Diaminopyridine for Lambert-Eaton Myasthenic Syndrome (LEMS) and Congenital Myasthenia (CM)

Lambert-Eaton Myasthenic Syndrome (LEMS) | Congenital Myasthenia (CM)

United States
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A Clinical Trial to Evaluate JAB-21822 Drug-drug Interactions in Healthy Subjects

Healthy Subjects

China
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A Study of JAB-21822 in Patients With KRAS p.G12C Mutated Pancreatic Cancer

Pancreatic Cancer | KRAS P.G12C

China
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

Phase 1/2a Study of JAB-21822 Plus JAB-3312 in Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation

Colorectal Cancer | Non-small Cell Lung Cancer | Pancreatic Ductal Carcinoma | KRAS P.G12C

China
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A Study of JAB-21822 in Advanced or Metastatic NSCLC With KRAS p.G12C and STK11 Co-mutation and Wild-type KEAP1

Non-small Cell Lung Cancer

China
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

JAB-21822 in Combination With Cetuximab in Patients With Advanced CRC and Other Solid Tumors With KRAS G12C Mutation

Advanced Colorectal Cancer | Small Intestinal Cancer | Appendiceal Cancer

China
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

FIH Study of JAB-21822 in Adult Patients With Advanced Solid Tumors Harboring KRAS G12C Mutation in China

NSCLC | Solid Tumor | CRC

China
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

JAB-21822 Activity in Adult Patients With Advanced Solid Tumors Harboring KRAS G12C Mutation

NSCLC | Advanced Solid Tumor | CRC

United States
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A Study of JAB-3312 in Adult Patients With Advanced Solid Tumors in China

Breast Cancer | Colorectal Cancer | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Other Solid Tumors | Pancreatic Ductal Carcinoma

China
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A First-in-Human Study of JAB-3068 (SHP2 Inhibitor) in Adult Patients With Advanced Solid Tumors in China

Head and Neck Cancer | Esophageal Cancer | Non-small Cell Lung Cancer | Other Metastatic Solid Tumors

China
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A First in Human, Dose Escalation Study of JAB-3068 （SHP2 Inhibitor） in Adult Patients With Advanced Solid Tumors

Head and Neck Cancer | Esophageal Cancer | Non-small Cell Lung Cancer | Other Metastatic Solid Tumors

United States
Jacobio Pharmaceuticals Co., Ltd.

Completed

A Food Effect Study of JAB-21822 in Healthy Subjects

Food Effect in Healthy Participants

China
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

JAB-2485 Activity in Adult Patients With Advanced Solid Tumors

Solid Tumors | ER+ Breast Cancer | ARID1A Gene Mutation | Triple Negative Breast Cancer, TNBC | Small Cell Lung Cancer, SCLC

United States, China
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors

NSCLC | AML | SCLC | Ovarian Carcinoma | Malignant Tumor | ESCC | CRPC | MF

China
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A First-in-Human Study of JAB-8263 in Adult Patients With Advanced Solid Tumors

Solid Tumors, Adult

United States
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors

Breast Cancer | Colorectal Cancer | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Other Solid Tumors | Pancreatic Ductal Carcinoma

United States
Jacobio Pharmaceuticals Co., Ltd.

Completed

Mass Balance Study of [14C]JAB-21822

Mass Balance Study in Healthy Subjects

China
David Lacomis, MD
Jacobus Pharmaceutical

No longer available

Treatment of Lambert-Eaton Syndrome With 3,4 Diaminopyridine

Lambert-Eaton Myasthenic Syndrome
Jacobus Pharmaceutical

Completed

Dapsone 100 Mg Versus 50 as Primary Prophylaxis for Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS-Related Complex (ARC)

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Jacobus Pharmaceutical

Completed

A Comparison of Dapsone and Trimethoprim-Sulfamethoxazole in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Jacobio Pharmaceuticals Co., Ltd.
AbbVie

Recruiting

JAB-3312 Based Combination Therapy in Adult Patients With Advanced Solid Tumors

NSCLC | Solid Tumor

United States
Jacobio Pharmaceuticals Co., Ltd.
AbbVie

Recruiting

JAB-3068 Activity in Adult Patients With Advanced Solid Tumors

Non Small Cell Lung Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma

China
David P. Richman, MD
Jacobus Pharmaceutical

No longer available

Treatment of Lambert-Eaton Syndrome With 3,4 DAP

Lambert Eaton Myasthenic Syndrome

United States
National Institute of Allergy and Infectious Diseases...
Jacobus Pharmaceutical

Completed

Comparison of Two Dosage Regimens of Oral Dapsone for Prophylaxis of Pneumocystis Carinii Pneumonia in Pediatric HIV Infection

HIV Infections | Pneumonia, Pneumocystis Carinii

United States, Puerto Rico
Jeffrey A. Cohen, MD
Jacobus Pharmaceutical

Terminated

Controlled Trial of 3,4-Diaminopyridine (3-4DAP) in Lambert-Eaton Myasthenic Syndrome (LEMS) (3-4DAP)

Muscle Weakness

United States
U.S. Bioscience
Jacobus Pharmaceutical

Completed

Randomized Phase I Study of Trimetrexate Glucuronate (TMTX) With Leucovorin (LCV) Protection Plus Dapsone Versus Trimethoprim / Sulfamethoxazole (TMP/SMX) for Treatment of Moderately Severe Episodes of Pneumocystis Carinii Pneumonia

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
National Institute of Allergy and Infectious Diseases...
Jacobus Pharmaceutical; Fujisawa Pharmaceutical Co

Completed

A Study of Pentamidine Plus Dapsone in the Prevention of Pneumocystis Carinii Pneumonia (PCP) in HIV-Infected Patients Who Cannot Take Trimethoprim or Sulfonamides

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
National Institute of Allergy and Infectious Diseases...
Jacobus Pharmaceutical; Glaxo Wellcome

Completed

A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Jacobs University Bremen gGmbH

Completed

Spiroergometric and Psychological Measurements to Predict Return to Work After 18 and 36 Months After Medical Rehab (SPIRO)

Employability

Germany
Jacobs University Bremen gGmbH

Recruiting

Planetary Health and Loneliness (PAL)

Anxiety | Health Behavior | Loneliness | Healthy Diet | Health-Related Behavior | Healthy Lifestyle | Healthy Nutrition

Germany
Jacobs University Bremen gGmbH

Completed

Prevention of Reduced Employability With an Expert System With Telephone, Motivational Interviews Supporting Self-management (EXPERTIS)

Employability

Germany
Jacobio Pharmaceuticals Co., Ltd.
Merck Sharp & Dohme LLC

Recruiting

JAB-BX102 Monotherapy and Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors

Solid Tumor

China
Jacobi Medical Center

Completed

Pericapsular Nerve Group Block for Hip Fractures

Hip Fractures | Pain, Acute

United States
Jacobi Medical Center

Completed

Video Tool to Promote Knowledge of Syphilis as Facilitator of HIV Transmission

Syphilis

United States
Joshua S. Jacobs, MD

Approved for marketing

Expanded Access for Hereditary Angioedema (HAE)
Cale Jacobs, PhD

Completed

Early Anti-inflammatory Treatment in Patients With Acute ACL Tear and Painful Effusions (HEALR)

Anterior Cruciate Ligament

United States
Cale Jacobs, PhD

Terminated

IL-1RA Treatment in Patients With Acute ACL Tear and Painful Effusions (EASI ACL)

Anterior Cruciate Ligament Tear

United States
Jacobs University Bremen gGmbH
Liveonline Coaching

Completed

Liveonline Training Course to Improve Food Habits and Enhance Physical Activity in Older Adults (LIFE!)

Motivation | Impaired Health

Germany
University of California, Irvine
Jacobs Foundation

Completed

SSIs for Mental Health and Loneliness

Depression | Stress | Anxiety | Loneliness | Distress, Emotional | Mental Health Issue

United States
Jacobi Medical Center

Unknown

Prospective Bone Marrow Biopsy Safety and Efficacy Study

Bone Marrow
Jacobi Medical Center
Cumberland Pharmaceuticals; Sagatech Electronics Inc, Alberta, Canada

Completed

Intravenous Ibuprofen for Laparoscopic Bariatric Surgery

Obesity

United States
Novartis Pharmaceuticals
Chugai Pharmaceutical

Completed

Study of Safety and Efficacy of Letrozole Monotherapy as Second-line Endocrine Therapy in Postmenopausal Patients With Advanced Breast Cancer Who Received Previous Anti-estrogen Treatment

Postmenopausal Women With Advanced Breast Cancer

Japan
Novartis Pharmaceuticals
Chugai Pharmaceutical

Completed

Extension Study of 1.0mg Dose Letrozole Therapy in Postmenopausal Patients With Breast Cancer

Postmenopausal Women With Advanced Breast Cancer

Japan
Novartis Pharmaceuticals
Chugai Pharmaceutical

Completed

Study of High-dose Letrozole Therapy in Postmenopausal Patients With Breast Cancer

Postmenopausal Women With Advanced Breast Cancer

Japan
Cale Jacobs
Vanderbilt University

Completed

Early Treatment for Acute ACL Tear (AAA)

Anterior Cruciate Ligament (ACL) Tears

United States
University at Buffalo
University at Buffalo Jacobs Institute

Recruiting

Assessing the Safety and Effectiveness of a Neurological Thrombectomy Medical Device for Acute Ischemic Stroke

Ischemic Stroke

United States

Clinical Trials Sponsored by Jacobus Pharmaceutical

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Angola

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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