Clinical Trials Sponsored by Juvenile Diabetes Research Foundation

Total 346 results

Medtronic Diabetes
Juvenile Diabetes Research Foundation

Completed

Effect of Closed Loop Glucose Control on Exercise-Associated Hypoglycemia (ePID-03)

Type 1 Diabetes Mellitus

United States
AstraZeneca
Juvenile Diabetes Research Foundation

Completed

Effect of a Fixed Pramlintide: Insulin Dose Ratio on Postprandial Glucose in Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

United States
GlaxoSmithKline
Juvenile Diabetes Research Foundation

Completed

Trial of Otelixizumab for Adults With Newly Diagnosed Type 1 Diabetes Mellitus (Autoimmune): DEFEND-1 (DEFEND-1)

Diabetes Mellitus, Type 1

United States, Finland, Sweden, Italy, Spain, United Kingdom, Germany, Canada, Denmark
AstraZeneca
Juvenile Diabetes Research Foundation

Completed

Effect of Different Fixed Pramlintide:Insulin Dose Ratios on Postprandial Glucose in T1DM

Type 1 Diabetes

United States
GlaxoSmithKline
Juvenile Diabetes Research Foundation

Terminated

TRX4 Monoclonal Antibody in Type 1 Diabetes (T1 DM) (TTEDD)

Diabetes Mellitus, Type 1

United States, Canada
GlaxoSmithKline
Juvenile Diabetes Research Foundation

Completed

Trial of Otelixizumab for Adolescents and Adults With Newly Diagnosed Type 1 Diabetes Mellitus (Autoimmune): DEFEND-2 (DEFEND-2)

Diabetes Mellitus, Type 1

Italy
CoMentis
Juvenile Diabetes Research Foundation

Completed

Topical Ocular Mecamylamine in Diabetic Macular Edema (DME)

Diabetic Macular Edema

United States
Joslin Diabetes Center
Juvenile Diabetes Research Foundation

Completed

Effect of Gain on Closed-Loop Insulin

Type 1 Diabetes

United States
Sansum Diabetes Research Institute
Juvenile Diabetes Research Foundation

Completed

Feasibility Study Using Zone-MPC Controller, HMS and Technosphere® Insulin Inhalation System From MannnKind Corp

Type 1 Diabetes Mellitus

United States
Indiana University
Juvenile Diabetes Research Foundation

Completed

Identification of β Cell Dysfunction in Relatives of Individuals With Type 1 Diabetes Mellitus

Type 1 Diabetes

United States
Lund University
Juvenile Diabetes Research Foundation

Active, not recruiting

TEFA Family Prevention: Glutenfree Diet to Preserve Beta-cell Function (TEFA)

Type 1 Diabetes | Prediabetes

Sweden
Yale University
Juvenile Diabetes Research Foundation

Completed

Effect of a Medium Chain Triglyceride Supplemented Diet on Cognitive Function and Brain Activation in Type 1 Diabetes.

Hypo-unawareness | Type 1 Diabetes Mellitus

United States
Indiana University
Juvenile Diabetes Research Foundation

Completed

Prospective Study of the Impact of Insulin Pump Therapy in Young Children With Type 1 Diabetes

Type 1 Diabetes

United States
Emory University
Juvenile Diabetes Research Foundation

Completed

Islet Transplantation in Type 1 Diabetics Using the Edmonton Protocol of Steroid Free Immunosuppression

Diabetes Mellitus, Type 1

United States
Yale University
Juvenile Diabetes Research Foundation

Completed

Diluted Insulin in Young Children: Bigger Volumes for Smaller Patients

Type1diabetes

United States
Yale University
Juvenile Diabetes Research Foundation

Terminated

Pathogenesis of the Cardiometabolic Risk in Youth With Type 1 Diabetes

Type 1 Diabetes | De Novo Lipogenesis

United States
McGill University
Juvenile Diabetes Research Foundation

Completed

Alleviating Carbohydrate Counting for Patients With Type 1 Diabetes Using a Novel Insulin-plus-pramlintide Artificial Pancreas

Type 1 Diabetes | Type 1 Diabetes Mellitus | Hyperglycemia, Postprandial

Canada
McGill University
Juvenile Diabetes Research Foundation

Completed

Pramlintide and Fiasp Closed-Loop With a Simple Meal Announcement

Type 1 Diabetes Mellitus

Canada
McGill University
Juvenile Diabetes Research Foundation

Completed

Effect of Basal-Bolus Closed-Loop Co-Administration of Insulin and Pramlintide on Improving the Glycemic Control in Type 1 Diabetes

Diabetes Mellitus, Type 1

Canada
Sanford Health
Juvenile Diabetes Research Foundation

Completed

Combination Therapy With Sitagliptin and Lansoprazole to Restore Pancreatic Beta Cell Function in Recent-Onset Type 1 Diabetes (REPAIR-T1D)

Type 1 Diabetes

United States
St Vincent's Institute of Medical Research
Juvenile Diabetes Research Foundation; Juvenile Diabetes Research Foundation...

Active, not recruiting

Baricitinib in New-onset Type 1 Diabetes (BANDIT)

Type 1 Diabetes

Australia
vTv Therapeutics
Juvenile Diabetes Research Foundation

Completed

Evaluation of TTP399 in Patients With Type 1 Diabetes (SimpliciT1)

Diabetes Mellitus, Type 1

United States
Sangamo Therapeutics
Juvenile Diabetes Research Foundation

Completed

Clinical Trial of SB-509 in Subjects With Diabetic Neuropathy

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Diabetic Polyneuropathy

United States
Emory University
Juvenile Diabetes Research Foundation

Completed

Islet Transplantation Using Abatacept

Type 1 Diabetes Mellitus

United States
Indiana University
Juvenile Diabetes Research Foundation

Completed

Long Term Effects of Diabetes of Very Young Children

Type 1 Diabetes

United States
Sangamo Therapeutics
Juvenile Diabetes Research Foundation

Completed

Clinical Trial of SB-509 in Subjects With Diabetic Neuropathy

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Diabetic Polyneuropathy

United States, Mexico
Steno Diabetes Center Copenhagen
Juvenile Diabetes Research Foundation

Unknown

GABA Treatment in Subjects With Type 1 Diabetes (GABA-1)

Type 1 Diabetes Mellitus

Denmark
University of Alberta
Juvenile Diabetes Research Foundation; Juvenile Diabetes Research Foundation...

Active, not recruiting

cePolyTregs in Islet Transplantation (cePolyTregs)

Diabetes type1

Canada
University of Michigan
Juvenile Diabetes Research Foundation

Recruiting

Ecological Momentary Assessment Study of Adolescents and Young Adults With Type 1 Diabetes (EMA-T1D)

Type 1 Diabetes

United States
Carnegie Mellon University
Juvenile Diabetes Research Foundation

Recruiting

Pilot Brief Communal Coping Intervention for Adults With Type 1 Diabetes

Diabetes Mellitus, Type 1

United States
Rabin Medical Center
Juvenile Diabetes Research Foundation

Recruiting

Screening for Islet Autoantibodies in the Israeli Paediatric General Population for Detection of Pre-symptomatic Type-1 Diabetes Mellitus (ADIR)

Type1diabetes

Israel
Nemours Children's Clinic
Juvenile Diabetes Research Foundation

Completed

Glutathione Metabolism in Adolescents With Type 1 Diabetes - Study A

Diabetes Mellitus, Type 1

United States
University Hospital, Montpellier
Juvenile Diabetes Research Foundation

Terminated

Root Cause Determination of Catheter Obstructions (CATS)

Type1diabetes

France
University of Dundee
Juvenile Diabetes Research Foundation

Completed

Use of Diazoxide in Acute Hypoglycaemia

Type 1 Diabetes

United Kingdom
University of Calgary
Juvenile Diabetes Research Foundation

Completed

Corneal Confocal Microscopy to Detect Diabetic Neuropathy in Children (CCM)

Type 1 Diabetes | Neuropathy | Retinopathy

Canada
Legacy Health System
Juvenile Diabetes Research Foundation

Completed

Artificial Pancreas Control System in an Outpatient Setting

Type 1 Diabetes Mellitus

United States
XOMA (US) LLC
Juvenile Diabetes Research Foundation

Completed

Study of the Effects of XOMA 052 on Insulin Production in Subjects With Well Controlled Type 1 Diabetes

Type 1 Diabetes

Switzerland
University of Michigan
Juvenile Diabetes Research Foundation

Recruiting

Metabolic Phenotypes and Heterogeneity in Disease Burden Risk in Type 1 Diabetes (JDRF-COE)

Diabetes Mellitus

United States
University of Alberta
Juvenile Diabetes Research Foundation

Recruiting

Device-Less Technique in Islet Transplantation

Type 1 Diabetes

Canada
University of Florida
Juvenile Diabetes Research Foundation

Recruiting

Lactobacillus Johnsonii in Children and Adolescents With T1D

Type 1 Diabetes (T1D)

United States
Nemours Children's Clinic
Juvenile Diabetes Research Foundation

Completed

Glutathione Metabolism in Adolescents With Type 1 Diabetes - Study B

Diabetes Mellitus, Type 1

United States
Lexicon Pharmaceuticals
Sanofi; Juvenile Diabetes Research Foundation

Completed

Efficacy and Safety of Sotagliflozin in Young Adult Patients With Type 1 Diabetes Mellitus and Elevated Hemoglobin A1C

Type 1 Diabetes Mellitus

United States
University of Florida
Juvenile Diabetes Research Foundation

Completed

Safety, Tolerability and Host Response to Lactobacillus Johnsonii (LJ)

Healthy

United States
Sheba Medical Center
Juvenile Diabetes Research Foundation

Completed

Applying the "New Authority" Model in the Treatment of Poorly Controlled Diabetic Adolescents and Their Families

Type 1 Diabetes

Israel
University of Minnesota
Juvenile Diabetes Research Foundation

Terminated

Raptiva and Sirolimus in Islet Transplantation for Type 1 Diabetes (RAPTIVA)

Hypoglycemia | Type 1 Diabetes Mellitus

United States
Johns Hopkins University
Juvenile Diabetes Research Foundation

Completed

Ranibizumab for Edema of the Macula in Diabetes: Protocol 3 With High Dose - the READ 3 Study (READ 3)

Diabetic Macular Edema

United States
KalVista Pharmaceuticals, Ltd.
Juvenile Diabetes Research Foundation

Completed

A Phase I Single Ascending Dose Study of the Intravitreal Plasma Kallikrein Inhibitor KVD001 in Subjects With DME

Diabetic Macular Edema

United States
University of Michigan
Juvenile Diabetes Research Foundation

Completed

An Intervention Trial for Cardiac Neuropathy in Type 1 Diabetes

Diabetic Autonomic Neuropathy

United States
Legacy Health System
Juvenile Diabetes Research Foundation

Completed

Continuous Glucose Monitoring to Measure Effect of Glycemic Index

Type 1 Diabetes Mellitus

United States
Ospedale San Raffaele
Juvenile Diabetes Research Foundation

Completed

Calcineurin Inhibitor (CNI)-Free Immunosuppressive Regimen in T1D Patients Receiving Islet Transplantation (ECIT-1)

Type 1 Diabetes

Italy, Switzerland

Clinical Trials Sponsored by Juvenile Diabetes Research Foundation

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