Clinical Trials Sponsored by Karuna Therapeutics

Total 6679 results

Karuna Therapeutics

Recruiting

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1) (ADEPT-1)

Psychosis Associated With Alzheimer's Disease

United States, Spain, Slovakia, Bulgaria, France, Czechia, Italy, Serbia, Germany, Croatia
Karuna Therapeutics

Enrolling by invitation

Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

Psychosis Associated With Alzheimer's Disease

United States
Karuna Therapeutics

Enrolling by invitation

An Extension Study to Assess Long-Term Safety and Tolerability of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia

Schizophrenia

United States, Bulgaria, Serbia
Karuna Therapeutics

Completed

An Extension Study to Assess Long-term Safety, Tolerability, and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-4)

Schizophrenia

United States, Ukraine
Karuna Therapeutics

Active, not recruiting

An Open-label Study to Assess the Long-term Safety, Tolerability, and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-5)

Schizophrenia

United States
Karuna Therapeutics

Recruiting

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)

Psychosis Associated With Alzheimer's Disease

United States, Korea, Republic of
Karuna Therapeutics

Recruiting

A Study to Assess Efficacy and Safety of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia (ARISE)

Schizophrenia

United States, Bulgaria, Serbia
Karuna Therapeutics

Completed

A Study to Assess Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Adult Patients With Schizophrenia (EMERGENT-2)

Schizophrenia | Schizophrenia; Psychosis

United States
Karuna Therapeutics

Terminated

An Open-label Study to Assess the Long-term Safety, Tolerability, Effectiveness, and Durability of Effect of KarXT in Patients With DSM-5 Diagnosis of Schizophrenia (PENNANT)

Schizophrenia

United States
Karuna Therapeutics

Completed

A Study to Assess Safety and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-1)

Schizophrenia

United States
Karuna Therapeutics

Completed

Pilot Study Comparing Effects of Xanomeline Alone to Xanomeline Plus Trospium

Schizophrenia

United States
Karuna Therapeutics

Completed

A Study to Assess Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Adult Patients With Schizophrenia (EMERGENT-3)

Schizophrenia | Schizophrenia; Psychosis

United States, Ukraine
Karuna Therapeutics
Zai Lab (Shanghai) Co., Ltd.

Recruiting

A Study to Assess the Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Chinese Adult Subjects With DSM-5 Schizophrenia (UNITE-001)

Schizophrenia

China
Karus Therapeutics Limited

Completed

Safety,Tolerability and MTD KA2507 (HDAC6 Inhibitor) in Patients With Solid Tumours (HDAC6i)

Solid Tumor, Adult

United States
Arana Therapeutics Ltd

Terminated

Dose Ranging Study of ART621 in Subjects Diagnosed With Rheumatoid Arthritis Taking Methotrexate

Rheumatoid Arthritis

United States, Australia, Poland, Argentina, Czech Republic, India, Malaysia, New Zealand
Karus Therapeutics Limited

Completed

The Safety, Pharmacokinetic and Pharmacodynamic Effect of KA2237 (PI3 Kinase p110β/δ Inhibitor) In B Cell Lymphoma

Lymphoma, B Cell

United States
Karuna Labs Inc.

Completed

Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chronic Pain

Rheumatoid Arthritis | Low Back Pain | Chronic Pain | Carpal Tunnel Syndrome | Fibromyalgia | Complex Regional Pain Syndromes | Upper Extremity Dysfunction | Phantom Limb Pain | Repetitive Strain Injury

United States
St Marina University Hospital, Varna, Bulgaria

Completed

Lactobacillus Reuteri ProGastria in Helicobacter Pylori-infected Adult Subjects on Proton Pump Inhibitors

Helicobacter Pylori Infection

Bulgaria
St Marina University Hospital, Varna, Bulgaria

Completed

Probiotic Lactobacillus Reuteri to Prevent Antibiotic-associated Diarrhea and Clostridium Difficile-related Infections in Hospitalized Children (AADreuter)

Gastroenteritis | Clostridium Difficile Infection | Antibiotic Associated Diarrhea

Bulgaria
Karuna Labs Inc.

Completed

Embodiment in Virtual Reality as a Telemedicine Digital Therapeutic for the Treatment of Chronic Shoulder Pain

Low Back Pain | Chronic Pain | Shoulder Pain

United States
Karus Therapeutics Limited
University College, London

Withdrawn

A Study of Selective HDAC6 Inhibition With KA2507 in Advanced Biliary Tract Cancer

Biliary Tract Cancer

United Kingdom
Arana Therapeutics Ltd
Trident Clinical Research Pty Ltd

Completed

Dose Optimisation Study of ART621 in Subjects Diagnosed With Rheumatoid Arthritis Taking Methotrexate

Rheumatoid Arthritis

Sri Lanka
National Eye Centre, Kaduna

Completed

A Comparison of One-site and Two-site Peribulbar Anaesthesia for Cataract Surgery at Kaduna, Nigeria

Anaesthesia | Cataract

Nigeria
Kariya Pharmaceuticals

Not yet recruiting

Phase I Study to Evaluate KP405 in Healthy and Parkinson's Disease Patients

Tolerance | Safety Issues
Larena SAS

Not yet recruiting

The Benefits of Dietary and Micro-nutritional Management for Well-being at Work (MEDEIS)

Well-Being, Psychological

France
Larena SAS

Recruiting

Kinetic of Compounds of a Melatonin-based Formulation in Healthy Subjects

Melatonin Bioavailability

France
Larena SAS

Completed

Management of Occasional or Anticipatory Stress by Consumers of a Food Supplement (MELIM)

Stress

France
Larena SAS

Completed

Effect of Lactibiane Tolerance® to Treat Leaky Gut in Irritable Bowel Syndrome With Predominant Diarrhea (IBS-D)Patients

IBS - Irritable Bowel Syndrome

Italy
Ranok Therapeutics (Hangzhou) Co., Ltd.

Recruiting

A Study of RNK05047 in Subjects With Advanced Solid Tumors/Diffuse Large B-cell Lymphoma (CHAMP-1)

Advanced Solid Tumor | DLBCL

United States
Karen Reckamp, MD, MS
Enviro Therapeutics, Inc.

Recruiting

Study of Osimertinib With Carotuximab in Advanced, EGFR-mutated Non-Small Cell Lung Cancer

Lung Cancer | Non Small Cell Lung Cancer

United States
Carina Biotech Limited

Recruiting

A Study of CNA3103 (LGR5-targeted, Autologous CAR-T Cells) Administered to Subjects With Metastatic Colorectal Cancer

Colorectal Cancer Metastatic

Australia
PiLeJe

Completed

Study of a Management Strategy of Functional Bowel Disordes Related to Irritable Bowel Syndrome (IBS) With a Mixture of 8 Microbiotic Strains

Irritable Bowel Syndrome

France
PiLeJe

Completed

Efficacy of Supplementation With Probiotics as Adjuvant to Mechanical Treatment in Chronic Periodontitis

Probiotics, Periodontitis

France
PiLeJe

Completed

Gycabiane and Glycemic Control of Prediabetic Subjects

Hyperglycemia

France
Laguna Pharmaceuticals, Inc.

Terminated

Safety and Efficacy of Vanoxerine for the Conversion of Subjects With Recent Onset Atrial Fibrillation or Flutter to Normal Sinus Rhythm (RESTORE SR)

Atrial Fibrillation or Flutter

United States, Bulgaria, Russian Federation, Hungary, Israel
Karina Vejrum Sørensen

Unknown

Effect of Dietary Oils as G-protein-coupled Receptor Agonists on Glucose Tolerance

Obesity | Type 2 Diabetes Mellitus

Denmark
Larena SAS
BioFortis

Completed

Efficacy and Safety of Azeol Nasal Spray Versus Placebo in the Treatment of Early Symptoms of Common Cold in Adults (EXSPRAY)

Nasal Congestion

France
Laguna Pharmaceuticals, Inc.

Completed

Safety and Efficacy of Vanoxerine for Conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm (COR-ART)

Atrial Flutter | Symptomatic Atrial Fibrillation

Israel, Russian Federation
Arena Pharmaceuticals

Completed

Etrasimod Versus Placebo as Induction Therapy in Moderately to Severely Active Ulcerative Colitis (ELEVATE UC 12)

Ulcerative Colitis

United States, Spain, Israel, Netherlands, Australia, Korea, Republic of, Czechia, Italy, Russian Federation, Croatia, Portugal, Serbia, Belarus, Canada, Georgia, Hungary, Ukraine, Germany, Poland, Belgium, Turkey, Japan, Thailand, India and more
Arena Pharmaceuticals

Completed

Etrasimod Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis (ELEVATE UC 52)

Ulcerative Colitis

Israel, Spain, United States, Australia, Denmark, Korea, Republic of, Czechia, Russian Federation, Croatia, Portugal, Serbia, Taiwan, Canada, Bulgaria, Belarus, Georgia, Hungary, Italy, Latvia, Netherlands, Ukraine, Germany, Poland, B... and more
Arena Pharmaceuticals

Completed

A Study to Assess the Safety and Efficacy of Etrasimod in Subjects With Moderate-to-Severe Atopic Dermatitis (ADVISE)

Atopic Dermatitis

United States, Australia, Canada
Arena Pharmaceuticals

Terminated

Safety, Tolerability, and Efficacy of Etrasimod (APD334) in Participants With Primary Biliary Cholangitis

Primary Biliary Cholangitis

United States, Australia, New Zealand
Arena Pharmaceuticals

Completed

Tolerability, Pharmacokinetics, and Efficacy of APD371 in Participants With Crohn's Disease Experiencing Abdominal Pain

Abdominal Pain | Crohn's Disease

United States
Arena Pharmaceuticals

Terminated

Efficacy and Safety of Etrasimod (APD334) in Inflammatory Bowel Disease Patients With Active Skin Extra-intestinal Manifestations

Inflammatory Bowel Diseases | Skin Extra-intestinal Manifestations

Belgium, Germany, Serbia
Arena Pharmaceuticals

Completed

Single-Dose Safety Study of APD791 in Healthy Volunteers

Healthy

United States
PiLeJe

Completed

Irritable Bowel Syndrome and Lactibiane Tolerance

Irritable Bowel Syndrome

France
PiLeJe

Completed

Kinetic of Melatonin Subsequent to the Consumption of Melatonin-rich Food Supplements

Melatonin Bioavailability

France
Arjuna Natural Limited

Unknown

Effect of Indian Gooseberry Extract (AMX160) in Hypercholesterolemia

Hypercholesterolemia

Armenia
Arena Pharmaceuticals

Terminated

Olorinab in Irritable Bowel Syndrome With Predominant Constipation (IBS-C) and Irritable Bowel Syndrome With Predominant Diarrhea (IBS-D) (CAPTIVATE)

Irritable Bowel Syndrome

United States
Arena Pharmaceuticals

Completed

A Multiple-Dose Study to Assess the Safety, Tolerability, and Steady State Pharmacokinetics of APD791 in Healthy Volunteers

Healthy

United States

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