Clinical Trials Sponsored by Kompetenznetz Sepsis

Total 104 results

Kompetenznetz Sepsis
Bayer; AstraZeneca

Completed

Comparison of Two Antibiotic Regimen (Meropenem Versus Meropenem+Moxifloxacin)in the Treatment of Severe Sepsis and Septic Shock (MaxSep)

Septic Shock | Severe Sepsis

Germany
Kompetenznetz Sepsis
Biosyn; Brahms AG

Completed

Placebo Controlled Trial of Sodium Selenite and Procalcitonin Guided Antimicrobial Therapy in Severe Sepsis (SISPCT)

Septic Shock | Severe Sepsis

Germany
Sepsis Occurrence in Acutely Ill Patients

Completed

Dopamine and Norepinephrine in Shock Patients

Shock

Belgium, Austria, Spain
Seppic

Completed

Assessement of the Soothing Effect of a Food Supplement on Sensitive and Reactive Skin

Healthy Volunteers

Italy
Seppic

Completed

Evaluation of the Efficacy of a Dietary Supplement on Hair Loss and Hair Aspect

Healthy Volunteers

Italy
Seppic

Completed

Evaluation of the Efficacy of Two Dietary Supplements on Hair Loss and Hair Aspect

Healthy Volunteers

Italy
Seppic

Completed

Evaluation of the Efficacy of Two Dietary Supplements Claiming Anti-aging Properties

Healthy Volunteers

Italy
Hellenic Institute for the Study of Sepsis

Recruiting

STS Administration on Coronavirus Disease (COVID-19) Patients in Critical Care (H4COVID)

Virus Diseases | COVID-19 | Corona Virus Infection

Greece
Hellenic Institute for the Study of Sepsis

Active, not recruiting

Personalized Immunotherapy in Sepsis (ImmunoSep)

Sepsis

Greece, Germany, Netherlands, Romania, Switzerland
Hellenic Institute for the Study of Sepsis

Completed

Bacillus Calmette-guérin Vaccination to Prevent COVID-19 (ACTIVATEII)

Virus Diseases | COVID-19 | Chronic Obstructive Pulmonary Disease | Coronary Heart Disease | Corona Virus Infection

Greece
Hellenic Institute for the Study of Sepsis

Unknown

Incretin Hormones in Type 1 Diabetes Mellitus;Effect of Metformin Treatment (INCREDIBLE-M)

Type 1 Diabetes Mellitus

Greece
University of Athens
Hellenic Sepsis Study Group

Completed

Personalized Needs in Clostridium Difficile Infections (SPECIFY)

Biologic Markers | Clinical Markers

Greece
Center for Sepsis Control and Care, Germany

Completed

Medical Education for Sepsis Source Control and Antibiotics (MEDUSA)

Sepsis | Shock, Septic

Germany
Seppic

Recruiting

Evaluation of the Anti-aging Efficacy of Two Dietary Supplements

Healthy Volunteers

Italy
Hellenic Institute for the Study of Sepsis

Recruiting

Safety and Efficacy of Anakinra Treatment for Patients With Post Acute Covid Syndrome (PRECISION)

Long COVID | Post-Acute COVID-19 | Post-Acute COVID-19 Syndrome

Germany, Greece, Italy, Spain
Hellenic Institute for the Study of Sepsis

Recruiting

Assessing the Procalcitonin-guidance and Molecular-guided Diagnosis for Therapy of Severe Infections (the MODIFY Trial) (MODIFY)

Sepsis

Greece
University of Athens
Hellenic Sepsis Study Group

Recruiting

Functionality of Endogenous Biological Clock in Sepsis

Sepsis | Circadian Rhythm Disorders

Greece
Hellenic Institute for the Study of Sepsis

Completed

Distinguishing Bacterial and Viral Infections by MeMed BV® Test to Limit Gut Colonization by MDRO (CRONUS)

Respiratory Tract Infections | Bacterial Infections | Viral Infection | Multi-antibiotic Resistance

Greece
Hellenic Institute for the Study of Sepsis

Completed

Bezlotoxumab Yielded Outcomes by Addressing Personalized Needs in Clostridioides Difficile Infection (BEYOND)

Mortality | Clostridioides Difficile Infection | Organ Dysfunction Syndrome | Stool Microbiome | Clostridioides Difficile Infection Recurrence

Greece
Hellenic Institute for the Study of Sepsis

Completed

Addressing Personalized Needs in Clostridioides Difficile Infection (BEYOND)

Clostridioides Difficile Infection

Greece
Hellenic Institute for the Study of Sepsis

Completed

The Benefit of Bermekimab in Patients With Systemic Sclerosis

Scleroderma, Systemic

Greece
Hellenic Institute for the Study of Sepsis

Completed

suPAR-Guided Anakinra Treatment for Management of Severe Respiratory Failure by COVID-19 (SAVE-MORE)

Covid19

Greece, Italy
Hellenic Institute for the Study of Sepsis

Completed

Personalised Immunotherapy for SARS-CoV-2 (COVID-19) Associated With Organ Dysfunction (ESCAPE)

Virus Diseases | COVID-19 | Corona Virus Infection | Macrophage Activation Syndrome

Greece
Bionov
Seppic

Completed

Multicentre, Double-blind Study Versus Placebo on Impact and Safety of Extramel® 140 IU on Perceived Stress, Physical and Intellectual Fatigue, Pain Perception if Present, and the Impact on the Quality of Life (Ex Stress II)

Quality of Life | Pain | Fatigue | Life Stress
Prof. Dr. Wolfgang Hiddemann
Kompetenznetz Leukämien

Completed

Evaluation of "Dose-dense Therapy" by S-HAM in Comparison to Conventionally Timed Double Induction in Patients With Acute Myeloid Leukemia (AML) (AMLCG 2008)

Acute Myeloid Leukemia

Germany
Hellenic Institute for the Study of Sepsis

Recruiting

Clarithromycin Treatment to Prevent Sepsis Progression in CAP (REACT) (REACT)

Community-acquired Pneumonia

Greece
Hellenic Institute for the Study of Sepsis

Active, not recruiting

Use of Presepsin as a Marker for Immunotherapy Administration in Pneumonia (INSPIRE)

Hospital-acquired Pneumonia | Community-acquired Pneumonia

Greece
Hellenic Institute for the Study of Sepsis

Completed

Anti-inflammatory Action of Oral Clarithromycin in Community-acquired Pneumonia (ACCESS)

Sepsis | Mortality | Inflammatory Response | Biomarkers | SIRS | Community-acquired Pneumonia

Greece
Hellenic Institute for the Study of Sepsis

Completed

suPAR-guided Anakinra Treatment for Validation of the Risk and Management of Respiratory Failure by COVID-19 (SAVE) (SAVE)

Virus Diseases | COVID-19 | Corona Virus Infection | Lower Respiratory Tract Infection Viral

Greece
Hellenic Institute for the Study of Sepsis

Completed

Anti-inflammatory Clarithromycin for Improving COVID-19 Infection Early (ACHIEVE)

Virus Diseases | COVID-19 | Corona Virus Infection

Greece
Hellenic Institute for the Study of Sepsis

Unknown

suPAR to Guide Antibiotics in Emergency Department

Sepsis

Greece
Hellenic Institute for the Study of Sepsis

Completed

Pulse Photoplethysmography as an Early Tool for the Diagnosis of Sepsis (PROUD-1)

Sepsis

Greece
Hellenic Institute for the Study of Sepsis

Completed

A Trial of Validation and Restoration of Immune Dysfunction in Severe Infections and Sepsis (PROVIDE)

Sepsis | Macrophage Activation Syndrome

Greece
Hellenic Institute for the Study of Sepsis

Completed

A Clinical Trial of Procalcitonin-guided Antimicrobial Therapy in Sepsis (PROGRESS)

Sepsis

Greece
Spexis AG

Terminated

Pivotal Study in HER2 Negative, Locally Recurrent or Metastatic Breast Cancer (FORTRESS)

Metastatic Breast Cancer | Locally Recurrent Breast Cancer

Spain, Belgium, United States, United Kingdom, Korea, Republic of, Taiwan, Italy, Russian Federation, Czechia, France, Brazil, Argentina, Ukraine
Sensus Healthcare

Completed

A Retrospective Evaluation of Superficial Radiation Therapy (SRT) and Non-Melanoma Skin Cancer (NMSC)

Non-melanoma Skin Cancer

United States
Sensus Healthcare

Unknown

Superficial Radiation Therapy (SRT) for the Treatment of Recurrent Keloid Scars

Keloid Scar

United States
Sensus Healthcare

Unknown

A Retrospective Evaluation of Superficial Radiation Therapy (SRT) and Keloid Scars.

Keloid Scar
Hellenic Institute for the Study of Sepsis
The BioArte

Completed

NGS-Based Assay of Blood Samples of Sepsis Patients for Rapid Bacterial Identification (BIOARTE)

Pneumonia | Bacteremia | Acute Pyelonephritis | Biliary Tract Infection

Greece
Federal University of São Paulo
Latin America Sepsis Institute

Completed

Assessment of qSOFA in the Latin America Sepsis Institute Database

Sepsis
Hellenic Institute for the Study of Sepsis
European Commission

Completed

Benefit of Clarithromycin in Patients With Severe Infections Through Modulation of the Immune System (INCLASS)

Pneumonia | Sepsis | Mortality | Biomarkers | Respiratory Distress Syndrome | Multiple Organ Failure | Gram-Negative Bacteria Infection

Greece, Belgium
Monell Chemical Senses Center

Completed

Added Sugar Intake, Sweet Taste Phenotypes and Biomarkers (SWBIO)

Healthy

United States
Monell Chemical Senses Center

Completed

Shifting Salty Taste Preferences in Children

Development

United States
Oxford University Clinical Research Unit, Vietnam
Asia Pacific Sepsis Alliance

Completed

Management of Sepsis in Resource Limited Settings Using a Delphi Method.

Sepsis

Vietnam
Monell Chemical Senses Center

Completed

Sensitive Periods in Human Flavor Learning

Development

United States
Monell Chemical Senses Center

Completed

Taste Preferences for Nutritive and Non Nutritive Sweeteners Among Children and Adults (TNNS)

Development
Chinese Septic Shock Network

Completed

Strategy of Early Improvement of Tissue Oxygenation Decrease the Mortality of Severe Sepsis and Septic Shock

Shock, Septic

China
Hellenic Institute for the Study of Sepsis
Radboud University Medical Center

Completed

Bacillus Calmette-guérin Vaccination to Prevent Infections of the Elderly (ACTIVATE)

Mortality | Infection | Hospitalization

Greece
Seoul National University Hospital
Jeysis Medical

Not yet recruiting

Safety & Efficacy of Non-Invasive Procedures Using Ultrasound-Guided HIFU 'Sonotrip V20' in Symptomatic Uterine Fibroids

Myoma;Uterus
Center for Sepsis Control and Care, Germany
German Federal Ministry of Education and Research

Completed

Family Satisfaction (FS) in the Intensive Care Unit

Critical Illness

Germany

Clinical Trials Sponsored by Kompetenznetz Sepsis

Sponsors and Collaborators

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