Clinical Trials Sponsored by Lake Erie Research Institute

Total 66 results

Lake Erie Research Institute

Completed

RESTIFFIC™ Foot Wrap Reduces Moderate to Severe Restless Leg Syndrome (RESTIFFIC)

Restless Leg Syndrome

United States
Eric Bernicker, MD

Terminated

Trial of Radiation and Gene Therapy Before Nivolumab for Metastatic Non-Small Cell Lung Carcinoma and Uveal Melanoma (ENSIGN)

Nonsquamous Nonsmall Cell Neoplasm of Lung | Metastatic Uveal Melanoma | Lung Squamous Cell Carcinoma Stage IV

United States
Eric Y. Yang, MD PhD

Unknown

Primary Mitral Regurgitation Repair

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Prolapse | Ventricular Remodeling | Mitral Valve Disease | Degenerative Mitral Valve Disease | Chronic Mitral Disease | Myxomatous Mitral Valve Degeneration

United States
Erin Rothwell
National Human Genome Research Institute (NHGRI)

Not yet recruiting

Comparing Game Facilitated Interactivity to Genetic Counseling for Prenatal Screening Education

Pregnancy | Shared Decision Making | Genetic Testing | Genetic Counseling | Prenatal Disorder

United States
Eric Bernicker, MD
Millennium Pharmaceuticals, Inc.; The Methodist Hospital Research Institute

Withdrawn

Alsertib (MLN8237) and Brentuximab Vedotin for Relapsed/Refractory CD30-Positive Lymphomas and Solid Malignancies (AD3LE)

CD30-positive Lymphoma | CD30-positive Solid Tumor

United States
AdventHealth Translational Research Institute
Wake Forest University

Recruiting

Investigating the Effects of Aerobic and Resistance Training in Vivo on Skeletal Muscle Metabolism in Vitro in Primary Human Muscle Cells (MoTrMyo) (MoTrMyo)

Physical Activity

United States
Trinity Hypertension & Metabolic Research Institute
Wake Forest University

Unknown

The CHYMASE Angiotensin-(1-12) Axis in Cardiovascular Disease

Cardiovascular Disease

United States
Wake Forest University Health Sciences
HonorHealth Research Institute

Recruiting

Internet-delivered Management of Chemotherapy-Induced Peripheral Neuropathy (CIPN)

CIPN - Chemotherapy-Induced Peripheral Neuropathy

United States
Postgraduate Institute of Medical Education and...
AMRI Hospital, Salt Lake, Kolkata, India

Completed

Cmplications of ERCP (C-ERCP)

Complication of ERCP

India
Wake Forest University Health Sciences
Patient-Centered Outcomes Research Institute

Not yet recruiting

E-PRIME For Children With Medical Complexity (E-PRIME)

Children With Medical Complexity

United States
Wake Forest University Health Sciences
Patient-Centered Outcomes Research Institute

Recruiting

Incremental Hemodialysis: The TwoPlus Trial

End-Stage Kidney Disease

United States
Trinity Hypertension & Metabolic Research Institute
Wake Forest University Health Sciences

Recruiting

Chymase Angiotensin-(1-12) Axis In Hypertensive Disease

Hypertension

United States
Wake Forest University Health Sciences
Patient-Centered Outcomes Research Institute

Completed

Comparing Types of Implementation of a Shared Decision Making Intervention (ADAPT-NC)

Asthma

United States
Wake Forest University Health Sciences
Patient-Centered Outcomes Research Institute

Completed

Tranquil Moments II-CBT vs. Yoga for Worry

Anxiety

United States
Great Lakes NeuroTechnologies Inc.
National Institute of Nursing Research (NINR)

Unknown

Patient-Centered PD Ambulatory Monitoring System (ParkinPal)

Parkinson Disease

United States
Wake Forest University Health Sciences
National Institute of Nursing Research (NINR)

Active, not recruiting

Implementation and Effectiveness of Engagement and Collaborative Management to Proactively Advance Sepsis Survivorship (ENCOMPASS)

Sepsis

United States
Wake Forest University Health Sciences
Patient-Centered Outcomes Research Institute; Atrium Health Levine Cancer Institute

Completed

LCI-HEM-SCD-ST3P-UP-001: The Sickle Cell Trevor Thompson Transition Project (ST3P-UP Study) (ST3P-UP)

Sickle Cell Disease

United States
Wake Forest University Health Sciences
National Institute of Dental and Craniofacial Research (NIDCR)

Completed

Bacteria Entering the Blood Stream From Tooth Extractions and Tooth Brushing

Bacteremia

United States
Eric Hoffman
National Institute on Minority Health and Health Disparities (NIMHD); University... and other collaborators

Completed

Assessing Inherited Markers of Metabolic Syndrome in the Young (AIMMY)

Obesity | Diabetes Mellitus, Type 2 | Metabolic Syndrome

United States
Wake Forest University Health Sciences
Virginia Tech Carilion School of Medicine and Research Institute

Completed

QuitFast: Evaluating Transcranial Magnetic Stimulation as a Tool to Reduce Smoking Directly Following a Quit Attempt

Smoking | Smoking Cessation | Addiction | Nicotine Dependence | Craving | Addiction Nicotine | Cigarette Smoking

United States
University of Southern California
National Institute on Aging (NIA); Alzheimer's Therapeutic Research Institute; Wake Forest University Health Sciences

Completed

The Study of Nasal Insulin in the Fight Against Forgetfulness (SNIFF)

Alzheimer's Disease | Amnestic Mild Cognitive Impairment

United States
Wake Forest University Health Sciences
National Heart, Lung, and Blood Institute (NHLBI); Gramercy Research Group

Completed

Translating Dietary Trials Into the Community

Hypertension

United States
University of Waterloo
Canadian Institutes of Health Research (CIHR); YMCA; City of Lakes family Health... and other collaborators

Completed

Functional Exercise and Nutrition Education Program for Older Adults (MoveStrong)

Cardiovascular Diseases | Stroke | Kidney Diseases | Hypertension | Diabetes Mellitus | Cancer | Arthritis | Chronic Disease | Chronic Lung Disease | Congestive Heart Failure | Osteoporosis, Osteopenia | Frail

Canada
NorthShore University HealthSystem
National Cancer Institute (NCI); Wake Forest University Health Sciences; Van... and other collaborators

Completed

Clinical Validity and Utility of Genomic-targeted Chemoprevention of PCa: Aim 4a

Prostate Cancer | Prostate Cancer, Familial | Hereditary Prostate Cancer
Wake Forest University Health Sciences
OrthoCarolina Research Institute, Inc.; Virginia Commonwealth University; Orthopaedic... and other collaborators

Terminated

Radiation Therapy for Heterotopic Ossification Prophylaxis Acutely After Elbow Trauma (ElbowHO)

Elbow Fracture
Wright State University
Sanofi; University of Nebraska; University of Arizona; The Methodist Hospital Research... and other collaborators

Completed

Safety Trial of Single Versus Multiple Dose Thymoglobulin Induction in Kidney Transplantation (STAT)

End-Stage Renal Disease | Kidney Failure

United States
Wake Forest University
University of Colorado, Denver; University of Pittsburgh; National Institute... and other collaborators

Completed

Physical and Cognitive Function - Look AHEAD Ancillary Study

Diabetes | Weight Loss | Cognitive Function | Physical Function

United States
Massachusetts General Hospital
Medical University of South Carolina; Brown University; Wake Forest University... and other collaborators

Recruiting

Expanding First-line Options for Depression and Matching Treatments to Patients: Hatha Yoga vs. Behavioral Therapy

Depression

United States
Aarhus University Hospital
Aarhus University, Institute of Clinical Medicine; National Research Center...

Enrolling by invitation

The Impact of Late Effects After Treatment for Bladder Cancer on Quality of Life (CONQUER)

Bladder Cancer

Denmark
Wake Forest University Health Sciences
Patient-Centered Outcomes Research Institute; National Institute of Diabetes... and other collaborators

Recruiting

System Interventions to Achieve Early and Equitable Transplants (STEPS) Study

Chronic Kidney Diseases

United States
Pennington Biomedical Research Center
University of Colorado, Denver; University of Pittsburgh; Wake Forest University... and other collaborators

Recruiting

Aging and the Mitochondrial Response to Exercise Training, Measured by Noninvasive 31P Magnetic Resonance Spectroscopy (MoTrMito)

Physical Activity

United States
Wake Forest University Health Sciences
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Look AHEAD: Action for Health in Diabetes (LookAHEAD)

Myocardial Infarction | Stroke | Kidney Diseases | Diabetes | Bone Diseases | Dyslipidemia

United States
University of Utah
Baylor College of Medicine; National Institute of Nursing Research (NINR); University... and other collaborators

Completed

Mobile Decision Support System for Nurse Management of Neuromodulation Therapy

Parkinson's Disease

United States
Wake Forest University Health Sciences
Johns Hopkins University; The University of Texas Health Science Center, Houston and other collaborators

Recruiting

Long-term Effectiveness of the Antiobesity Medication Phentermine (LEAP)

Obesity | Lifestyle, Healthy | Obesity; Drug

United States
Mercator MedSystems, Inc.
University of South Florida; Northwestern University; Stony Brook University; Guy... and other collaborators

Recruiting

Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Subacute and Chronic Iliofemoral DVT (DEXTERITY-SCI)

Iliofemoral; Thrombosis

United States, Ireland, United Kingdom
Mercator MedSystems, Inc.
University of South Florida; Northwestern University; Stony Brook University; Guy... and other collaborators

Recruiting

Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Acute Femoropopliteal DVT (DEXTERITY-AFP)

Thrombosis, Deep Vein | Iliofemoral; Thrombosis

United States, Ireland, United Kingdom
University of California, Los Angeles
Patient-Centered Outcomes Research Institute; Yale University; University of... and other collaborators

Completed

D-CARE - The Dementia Care Study: A Pragmatic Clinical Trial of Health System-Based Versus Community-Based Dementia Care (D-CARE)

Dementia

United States
St. Louis University
Johns Hopkins University; Massachusetts General Hospital; Beth Israel Deaconess... and other collaborators

Recruiting

Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone

Giant Cell Tumor of Bone

United States, Canada, India
Wake Forest University Health Sciences
Icahn School of Medicine at Mount Sinai; University of Washington; Ohio State... and other collaborators

Completed

Amantadine for the Treatment of Traumatic Brain Injury Irritability and Aggression: A Multi-site Study

Aggression | Brain Injury

United States
University of Michigan Rogel Cancer Center
National Cancer Institute (NCI); Department of Health and Human Services; Early... and other collaborators

Recruiting

Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas

Colonic Neoplasms

United States, Canada, Australia
Wake Forest University Health Sciences
University of Pennsylvania; NYU Langone Health; Brigham and Women's Hospital; National... and other collaborators

Active, not recruiting

Observational Study of Dental Outcomes in Head and Neck Cancer Patients (ORARAD)

Head and Neck Cancer | Xerostomia | Osteoradionecrosis | Dental Disease

United States
Wake Forest University Health Sciences
University of Pennsylvania; NYU Langone Health; Brigham and Women's Hospital; National... and other collaborators

Active, not recruiting

Clinical Registry of Long-Term Dental Outcomes in Head and Neck Cancer Patients (ORARAD II)

Head and Neck Cancer | Osteoradionecrosis | Dental Diseases

United States
Wake Forest University
University of Missouri-Columbia; National Institute of Arthritis and Musculoskeletal... and other collaborators

Recruiting

The Osteoarthritis Prevention Study (TOPS)

Osteoarthritis, Knee

United States, Australia
University of Michigan
Johns Hopkins University; National Institute of Arthritis and Musculoskeletal... and other collaborators

Recruiting

Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow

Neuropathy Ulnar

United States
Wayne State University
Universiti Putra Malaysia; National Kidney Foundation; Ministry of Health, Malaysia and other collaborators

Completed

Palm Tocotrienols in Chronic Hemodialysis (USA) (PATCH)

End Stage Renal Disease | Chronic Kidney Disease

United States
Wake Forest University Health Sciences
National Institute on Drug Abuse (NIDA); Johns Hopkins University; M.D. Anderson... and other collaborators

Completed

Project 1, Study 1: Investigating the Impact of Nicotine Using Spectrum Cigarettes (P1S1)

Tobacco Dependence

United States
DARTNet Institute
University of Colorado, Denver; Icahn School of Medicine at Mount Sinai; Brigham... and other collaborators

Recruiting

Individualizing Treatment for Asthma in Primary Care (iTREAT-PC)

Respiratory Tract Infections | Immune System Diseases | Lung Diseases | Bronchial Diseases | Lung Diseases, Obstructive | Asthma | Respiratory Hypersensitivity

United States
University of Alabama at Birmingham
M.D. Anderson Cancer Center; National Cancer Institute (NCI); University of Colorado... and other collaborators

Active, not recruiting

Low-Dose Tamoxifen Citrate in Reducing Breast Cancer Risk in Radiation-Induced Cancer Survivors (LDTam)

Breast Cancer

United States, Canada
Brigham and Women's Hospital
Patient-Centered Outcomes Research Institute; Johns Hopkins University; University... and other collaborators

Completed

Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE)

Wounds and Injuries | Accidental Falls

United States
Albert Einstein College of Medicine
University of Pittsburgh; Brigham and Women's Hospital; Wake Forest University... and other collaborators

Withdrawn

Thyroxine Treatment in Premature Infants With Intraventricular Hemorrhage (IVHT4)

Intraventricular Hemorrhage of Prematurity

United States

Clinical Trials Sponsored by Lake Erie Research Institute

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Japan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations