Clinical Trials Sponsored by Lara McKenzie

Total 1207 results

Lara McKenzie

Completed

Make Safe Happen App Evaluation Study

Health Knowledge,Practices,Attitudes
Lara McKenzie

Completed

Evaluation of Spot Light: A Concussion Injury Management App for Youth Sports (SpotLight)

TBI

United States
Lara McKenzie

Completed

Emergency Department Brief Intervention to Increase Carbon Monoxide Detector Use (ProjectCODE)

Intervention-carbon Monoxide Alarm + Educational Tool | Control- Usual Care Flyer on Carbon Monoxide

United States
McKenzie Health System

Unknown

The Surgical Treatment of Type 2 Diabetes Mellitus in Non-Morbidly Obese Patients: A Community Hospital Study

Type 2 Diabetes Mellitus

United States
University of Florida
Scott R. MacKenzie Foundation

Completed

Pharmacodynamic and Pharmacokinetic of Switching From Cangrelor to Prasugrel in ACS Patients Undergoing PCI (SWAP-6)

Coronary Artery Disease | Acute Coronary Syndrome

United States
University of Florida
Scott R. MacKenzie Foundation

Completed

Impact of Chronic Kidney Disease on Clopidogrel Effects in Diabetes Mellitus

Coronary Artery Disease (CAD) | Type 2 Diabetes Mellitus (T2DM) | Chronic Kidney Disease (CKD)

United States
University of Florida
Scott R. MacKenzie Foundation

Not yet recruiting

Effects of Low-dose Ticagrelor vs. Clopidogrel in Stable Patients Undergoing Elective Percutaneous Coronary Intervention

Coronary Artery Disease

United States
University of Florida
Scott R. MacKenzie Foundation

Completed

PD and PK Profiles of Switching Between Cangrelor and Ticagrelor Following Ticagrelor Pre-treatment (SWAP-5)

Coronary Artery Disease

United States
University of Florida
Scott R. MacKenzie Foundation

Completed

Prasugrel Versus Ticagrelor in Patients With CYP2C19 Loss-of-function: a Validation Study

Coronary Artery Disease

United States
University of Sao Paulo
University Ghent; Universidade Presbiteriana Mackenzie

Completed

Neuro-modulation of the Depressed Brain Using Working Memory Training and Transcranial Direct Current Stimulation (tDCS)

Depression

Brazil
Lara Palacios

Recruiting

Impact of Clinical Ultrasound in Patients With Heart Failure Treated in Home Hospitalization (AHF-CU)

Acute Heart Failure (AHF)

Spain
Lyra Therapeutics

Recruiting

Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults (ENLIGHTEN 2)

Chronic Sinusitis | Chronic Rhinosinusitis (Diagnosis)

United States, Poland, Bulgaria, Belgium, Germany, Hungary
Lyra Therapeutics

Completed

LYR-220 for Adult Subjects With Chronic Rhinosinusitis (BEACON Study)

Chronic Sinusitis | Chronic Rhinosinusitis (Diagnosis)

United States, Australia
Lyra Therapeutics

Completed

LYR-210 Depot (LYR-210) for Adult Subjects With Chronic Sinusitis (LANTERN Study)

Chronic Sinusitis | Chronic Rhinosinusitis (Diagnosis)

Poland, Australia, New Zealand, Austria, Czechia
Lava Therapeutics

Recruiting

Trial of LAVA-1207 in Patients With Therapy Refractory Metastatic Castration Resistant Prostate Cancer

Metastatic Castration Resistant Prostate Cancer

United States
Lyra Therapeutics

Active, not recruiting

Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults (ENLIGHTEN 1)

Chronic Sinusitis | Chronic Rhinosinusitis (Diagnosis)

United States, Austria, Czechia, Poland, Spain
Lyra Therapeutics

Completed

480 Biomedical Sinus Drug Depot

Chronic Sinusitis

New Zealand, Australia
Lava Therapeutics

Active, not recruiting

Trial of LAVA-051 in Patients With Relapsed/Refractory CLL, MM, or AML

Acute Myeloid Leukemia | Multiple Myeloma | Chronic Lymphocytic Leukemia

United States, Spain, France, Netherlands
DARA Therapeutics

Completed

Neuropathic Pain in Patients With Cancer

Neuropathic Pain

United States, Puerto Rico
Cara Therapeutics, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica

Pruritus | Notalgia Paresthetica

United States, Poland, Spain, Canada, Germany
Cara Therapeutics, Inc.

Recruiting

A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States
Cara Therapeutics, Inc.

Terminated

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis (KIND-1)

Pruritus | Atopic Dermatitis

United States
Universiti Teknologi Mara

Completed

HIV Education Kit for Adolescents (Pencegahan HIV di Kalangan Remaja), PREM-Kit (PREM-Kit)

Human Immunodeficiency Virus

Malaysia
Cara Therapeutics, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States
Universiti Teknologi Mara

Active, not recruiting

Silver Diamine Fluoride: A Randomized Controlled Trial on Its Effectiveness As A Caries Arresting Agent

Quality of Life | Dental Caries

Malaysia
Cara Therapeutics, Inc.

Terminated

Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus

Cholestatic Pruritus

United States
Cara Therapeutics, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-1)

Uremic Pruritus

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis (KARE)

Pruritus | Atopic Dermatitis

United States, Canada
Universiti Teknologi Mara

Unknown

Low-Volume Interval Training and Resistance Exercise in Individual With Stroke

Stroke

Malaysia
Cara Therapeutics, Inc.

Completed

A Study Evaluating Pain Relief and Safety of Orally Administered CR845 in Patients With Osteoarthritis of Hip or Knee

Arthritis | Joint Diseases | Musculoskeletal Diseases | Rheumatic Diseases | Osteoarthritis, Knee | Osteoarthritis, Hip

United States
Cara Therapeutics, Inc.

Completed

Study to Investigate the Effects of Single Intravenous Doses of Difelikefalin (CR845) on the QTc Interval in Healthy Subjects

Healthy

United States
Universiti Teknologi Mara

Unknown

Physical Fitness, Exercise Self-efficacy, Physical Activity Level in People With Spinal Cord Injury (SCI)

Spinal Cord Injuries | Physical Disability
Cara Therapeutics, Inc.

Completed

A Study of the Safety and Effectiveness of Orally Administered CR845 in Patients With Osteoarthritis of the Hip or Knee

Osteoarthritis

United States
Cara Therapeutics, Inc.

Completed

Safety and Pharmacokinetics of IV CR845 in Hemodialysis Patients, and Its Efficacy in Patients With Uremic Pruritus

Pruritus | Uremic Pruritus

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate Analgesic Effect of Intravenous Administration of Kappa Agonist CR845 After Hysterectomy Surgery

Acute Pain

United States
Cara Therapeutics, Inc.

Completed

A Phase 2 Study to Evaluate Analgesic Effect of IV CR845 For Pain Following Bunionectomy Surgery

Acute Pain

United States
Nara Medical University

Completed

Angiotensin II Receptor Blockers (ARB) and ACE Inhibitors (ACEI) on Silent Brain Infarction and Cognitive Decline

Hypertension | Brain Infarction

Japan
Nara Medical University

Terminated

The Effects of Carperitide on Short and Long-term Prognosis in Patients With Both Cardiac and Renal Failure

Heart Failure | Renal Failure

Japan
Nara Medical University

Unknown

Hemofiltration for Contrast-Induced Nephropathy

Chronic Kidney Disease | Cardiac Catheterization

Japan
Federal University of São Paulo
University of Sao Paulo; Mackenzie Presbiterian University, São Paulo, Brazil

Completed

Multisite Study: Parental Training Using Video Modelling to Develop Social Skills in Children With Autism

Autism Spectrum Disorders

Brazil
Cara Medical Ltd

Recruiting

Cara CDRS (Conduction Disturbance Risk Score) 1.0 (CDRS)

Transcatheter Aortic Valve Replacement

Spain, Canada, Italy
Cara Medical Ltd

Recruiting

Cara CDRM (Conduction Disturbance Risk Monitor) 2.0 (Cara CDRM)

Transcatheter Aortic Valve Replacement

United States
Cara Therapeutics, Inc.

Recruiting

CR845-310302: A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States, Korea, Republic of, Australia, Bulgaria, Germany, Hungary, Italy, Poland, Romania, Spain, Argentina, Brazil, Mexico
Universiti Teknologi Mara

Completed

The Anticariogenic Effect of Silver Diamine Fluoride and Sodium Fluoride Varnish

Early Childhood Caries

Malaysia
Universiti Teknologi Mara

Completed

Behavior Intervention for Weight Loss for Type 2 Diabetes Mellitus Adults With Obesity Problem (BMI of ≥23kg/m2) (BMI)

Obesity | Diabetes Mellitus, Type 2 | Behavior

Malaysia
Cara Therapeutics, Inc.

Completed

CR845-100303: Study to Assess the Potential of Physical Withdrawal From Intravenous CR845 (Difelikefalin) in Hemodialysis Patients

Hemodialysis

United States
Cara Therapeutics, Inc.

Completed

CR845-CLIN3105: A Study to Evaluate the Safety and Effectiveness of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Uremic Pruritus

United States, Czechia, Hungary, Poland
Cara Therapeutics, Inc.

Completed

Extension Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Uremic Pruritus

United States, Puerto Rico
Cara Therapeutics, Inc.

Completed

Study to Evaluate the Pharmacokinetics and Metabolism of [14C] CR845 (Difelikefalin) in Patients With End Stage Renal Disease on Hemodialysis and in Healthy Subjects

Healthy | Hemodialysis

United States
Nara Medical University

Completed

New Angiotensin II Receptor Blocker Azilsartan Study for Stronger Blood Pressure Lowering (NARA)

Hypertension

Japan

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