Clinical Trials Sponsored by Leipzig Heart Institute GmbH

Total 47 results

Leipzig Heart Institute GmbH

Not yet recruiting

Personalised Risk scOre For Implantation of Defibrillators in Patients With Preserved LVEF>35% and a High Risk for Sudden Cardiac Death

Myocardial Infarction | Sudden Cardiac Death
Leipzig Heart Institute GmbH

Completed

Randomized Comparison of Catheter-based Strategies for Interventional Access Site Closure During Transfemoral Transcatheter Aortic Valve Implantation (CHOICE-CLOSURE)

Aortic Valve Stenosis

Germany
Leipzig Heart Institute GmbH

Completed

Fasting Versus Non-Fasting for Cardiac Implantable Electronic Devices (FastCIED Study)

Cardiac Implantable Electronic Devices

Germany
Leipzig Heart Institute GmbH

Not yet recruiting

Personalised Risk scOre For Implantation of Defibrillators in Patients With Reduced LVEF≤35% and a Low Risk for Sudden Cardiac Death (PROFID-Reduced)

Myocardial Infarction | Heart Failure | Sudden Cardiac Death
Leipzig Heart Institute GmbH

Suspended

Effect of Multielectrode Versus Point-by-Point Mapping on Recurrence of Ventricular Tachycardia in Ischemic Heart Disease (EMPIRE-VT)

Ventricular Tachycardia

Germany
Leipzig Heart Institute GmbH
Heart Center Leipzig - University Hospital

Unknown

Smart Watch iECG for the Detection of Cardiac Arrhythmias

Atrial Fibrillation | Arrhythmias, Cardiac

Germany
Leipzig Heart Institute GmbH
Heart Center Leipzig - University Hospital

Completed

Reducing Recurrence of Symptomatic Atrial Fibrillation After Catheter Ablation by App-based Mental Training (Mental-AF)

Paroxysmal Atrial Fibrillation | Persistent Atrial Fibrillation | Meditation

Germany
Leipzig Heart Science gGmbH
Heart Center Leipzig - University Hospital

Recruiting

RanDOmized stUdy Comparing Both Latest Generation Self-Expanding Valves and a Minimalist approaCH vs. Standard Of Care In transCathEter Aortic Valve Implantation (DOUBLE-CHOICE)

Aortic Valve Stenosis

Germany
University of Leipzig
Abbott Medical Devices; Leipzig Heart Institute GmbH; Zentrum für Klinische Studien...

Completed

Catheter Ablation Versus Amiodarone for Therapy of Premature Ventricular Contractions in Patients With Structural Heart Disease (CAT-PVC)

Heart Diseases | Cardiomyopathies | Ventricular Premature Complexes

Germany
Helios Health Institute GmbH
Heart Center Leipzig - University Hospital

Recruiting

Comparison of Vessel-FFR Versus FFR in Intermediate Coronary Stenoses (LIPSIASTRATEGY)

Coronary Artery Disease | Coronary Artery Stenoses

Germany
Helios Health Institute GmbH
Heart Center Leipzig - University Hospital

Recruiting

Complete Functional Assessment of Intermediate Coronary Artery Stenosis Before and After Transcatheter Aortic Valve Implantation (TAVI) in Patients With Severe Symptomatic Aortic Valve Stenosis (CHOICE-FR)

Coronary Artery Stenosis | Transcatheter Aortic Valve Implantation

Germany
Helios Health Institute GmbH
Heart Center Leipzig - University Hospital

Recruiting

Remote Ischemic Conditioning With Local Ischemic Postconditioning in High-Risk ST-elevation Myocardial Infarction (RIP-HIGH)

ST Elevation Myocardial Infarction

Austria, Germany
Helios Health Institute GmbH
Heart Center Leipzig - University Hospital

Terminated

Re-evaluation of Optimal Re-synchronisation Therapy in Patients With Chronic Heart Failure (RESET-CRT)

Chronic Heart Failure

Germany
Helios Health Institute GmbH
Heart Center Leipzig - University Hospital; IHF GmbH - Institut für Herzinfarktforschung

Active, not recruiting

Extracorporeal Life Support in Cardiogenic Shock (ECLS-SHOCK)

Acute Myocardial Infarction | Cardiogenic Shock

Germany
Leipzig Heart Science gGmbH
German Federal Ministry of Education and Research; IHF GmbH - Institut für... and other collaborators

Recruiting

Complete Revascularization Versus Culprit Lesion Only PCI in NSTEMI (CompleteNSTEMI)

Multivessel Coronary Artery Disease | Non-ST-elevation Myocardial Infarction

Germany
Charite University, Berlin, Germany
Leipzig Heart Science gGmbH

Recruiting

Prevention Of Sudden Cardiac Death After Myocardial Infarction by Defibrillator Implantation (PROFID EHRA)

Myocardial Infarction | Sudden Cardiac Death

Czechia, Austria, Germany
Leipzig Heart Science gGmbH
Charite University, Berlin, Germany; Klinikum Ludwigshafen; St. Antonius Hospital and other collaborators

Recruiting

German Cardiac Arrest Registry (G-CAR)

Out-of-hospital Cardiac Arrest

Germany
University of Leipzig
Institut für Gesundheits- und Praxismanagement GmbH

Withdrawn

Pioglitazone in Impaired Glucose Tolerance

Glucose Metabolism Disorders

Germany
Leipzig Heart Science gGmbH
Heart Center Leipzig - University Hospital; Zentrum für Klinische Studien Leipzig and other collaborators

Recruiting

Resuscitation Registry in CHD (PRO-CHD)

Cardiac Arrest | Congenital Heart Disease

Germany
German Heart Institute
Miltenyi Biomedicine GmbH

Completed

Bypass Surgery and CD133 Marrow Cell Injection for Treatment of Ischemic Heart Failure (Cardio133)

Congestive Heart Failure | Previous Myocardial Infarction | Coronary Artery Disease With Need for Bypass Surgery | Myocardial Ischemia, Angina Pectoris

Germany
National Heart and Lung Institute
Dr. Falk Pharma GmbH

Unknown

Ursodeoxycholic Acid in Chronic Heart Failure

Heart Failure, Congestive

United Kingdom
Leipzig Heart Institute GmbH
Charite University, Berlin, Germany; University Hospital Schleswig-Holstein... and other collaborators

Unknown

SecOnd-generation seLf-expandable Versus Balloon-expandable Valves and gEneral Versus Local Anesthesia in TAVI (SOLVE-TAVI)

Aortic Stenosis

Germany
Technische Universität Dresden
Charite University, Berlin, Germany; Klinikum St. Georg gGmbH; Universitätsklinikum... and other collaborators

Recruiting

Saxon SARS-CoV-2 Infection and Vaccination Study in Dialysis Patients, Solid Organ Recipients and Staff (DIA-Vacc)

Immune Response | SARS-CoV-2 Infection | Immunosuppression | Active Immunization

Germany
Medtronic Cardiac Rhythm and Heart Failure
IHF GmbH - Institut für Herzinfarktforschung

Completed

Postmarket Evaluation of the Phased Radio Frequency Ablation System (GOLD AF Registry)

Atrial Fibrillation

Spain, Korea, Republic of, Israel, France, Netherlands, Germany, United Kingdom, Hungary, Italy, Poland, Georgia, Greece, Portugal, Switzerland
Karolinska Institutet
Medtronic - MITG; Swedish Heart Lung Foundation; Phenox GmbH; Stryker Nordic

Completed

SITS (Safe Implementation of Treatments in Stroke) Open Artery by Thrombectomy in Acute Occlusive Stroke Study (SITS Open)

Ischemic Stroke

Sweden
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Treosulfan and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Nonmalignant Inherited Disorders

Non-Neoplastic Hematologic and Lymphocytic Disorder

United States
Heart Center Leipzig - University Hospital
University of Leipzig Medical Center, Department of Cardiology; Heart and Diabetes... and other collaborators

Not yet recruiting

Biomaterial Collection - and Analysis in Cardiac Sarcoidosis

Cardiac Sarcoidosis
Medical University of Graz
AIT Austrian Institute of Technology GmbH; Ludwig Boltzmann Institute for translational...

Unknown

Integrated Telemonitoring and Nurse Support Evaluation (INTENSE-HF)

Chronic Heart Failure

Austria
Ottawa Heart Institute Research Corporation
Far Eastern Memorial Hospital; London Health Sciences Centre; Medtronic; The Methodist... and other collaborators

Recruiting

The Minimally Invasive Coronary Surgery Compared to STernotomy Coronary Artery Bypass Grafting Trial (MIST)

Coronary Artery Disease

United States, Belgium, Canada, China, Germany, India, Japan, Singapore, Taiwan
Profil Institut für Stoffwechselforschung GmbH
Icahn School of Medicine at Mount Sinai; Heart and Diabetes Center North-Rhine...

Completed

Effects of Food Advanced Glycation Endproducts on Vascular Function in Diabetes

Type 2 Diabetes Mellitus

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Charite University, Berlin, Germany; Roche Pharma AG; Hoffmann-La Roche; Arbeitsgemeinschaft... and other collaborators

Recruiting

Rituximab in Combination With Glofitamab and Polatuzumab Vedotin in Patients With Previously Untreated Aggressive B-cell Lymphoma Ineligible for R-CHOP (R-Pola-Glo)

Lymphoma, Large B-Cell, Diffuse

Germany, Austria
GCP-Service International West GmbH
Saint-Louis Hospital, Paris, France; Groupe Francophone des Myelodysplasies; Australasian... and other collaborators

Recruiting

Study to Evaluate Imetelstat in Patients With High-Risk MDS or AML Failing HMA-based Therapy (IMpress)

Acute Myeloid Leukemia | Myelodysplastic Syndromes

Australia, France, Germany
German Heart Institute
University of Cologne; University Hospital Heidelberg; medneo GmbH, Germany; Medical... and other collaborators

Active, not recruiting

"HerzCheck" - Detection of Early Heart Failure Using Telemedicine in Structurally Weak Regions

Heart Failure With Preserved Ejection Fraction

Germany
Population Health Research Institute
Canadian Institutes of Health Research (CIHR); University of Leipzig; Heart and... and other collaborators

Completed

Home-Based Screening for Early Detection of Atrial Fibrillation in Primary Care Patients Aged 75 Years and Older (SCREEN-AF)

Hypertension | Atrial Fibrillation

Canada, Germany
Johannes Gutenberg University Mainz
Sanofi; Bayer; Boehringer Ingelheim; German Federal Ministry of Education and Research and other collaborators

Completed

Evaluation of Oral Anticoagulation With Vitamin K Antagonists - The thrombEVAL Study Programme (thrombEVAL)

Atrial Fibrillation | Venous Thromboembolism | Anticoagulant Antagonists, Vitamin K and Other Coagulants Causing Adverse Effects in Therapeutic Use

Germany
Norwegian University of Science and Technology
UMC Utrecht; Bispebjerg Hospital; Helse Stavanger HF; St. Olavs Hospital; University... and other collaborators

Completed

The SMARTEX Heart Failure Study (SMARTEX)

Heart Failure

Netherlands, Norway, Denmark, Belgium, Germany, Italy, Luxembourg
Oncoscience AG
Heinrich-Heine University, Duesseldorf; University of Wuerzburg; Children's Medical... and other collaborators

Completed

Nimotuzumab in Children With Intrinsic Pontine Glioma

Diffuse Instrinsic Ponitine Glioma

Germany
Peter Rossing
University Medical Center Groningen; European Commission; Istituto Di Ricerche... and other collaborators

Completed

Proteomic Prediction and Renin Angiotensin Aldosterone System Inhibition Prevention Of Early Diabetic nephRopathy In TYpe 2 Diabetic Patients With Normoalbuminuria (PRIORITY)

Diabetic Retinopathy | Diabetic Nephropathy

Netherlands, Belgium, Spain, Czechia, Germany, United Kingdom, Denmark, Greece, Italy, Macedonia, The Former Yugoslav Republic of
The First Affiliated Hospital with Nanjing Medical...
National University Hospital, Singapore; University of Pennsylvania; General... and other collaborators

Unknown

CPVI Alone Versus. CPVI Plus Electrophysiological Substrate Ablation in the LA During SR for the Treatment of Non-PAF (STABLE-SR_II)

Atrial Fibrillation

China
Universitätsklinikum Hamburg-Eppendorf
Lithuanian University of Health Sciences; Örebro University, Sweden; University... and other collaborators

Recruiting

Proof of Concept Human Study: Dietary Intervention to Modify Intestinal Inflammation in IBD

Reduction of Intestinal Inflammatory Activity

Germany
Helsinki University Central Hospital
Assistance Publique - Hôpitaux de Paris; Universitaire Ziekenhuizen KU Leuven; Azienda Ospedaliera Universitaria Integrata Verona and other collaborators

Active, not recruiting

European Registry of Type A Aortic Dissection (ERTAAD)

Type A Aortic Dissection

Spain, Belgium, Finland, United Kingdom, Germany, Italy, Czechia, France
Medical University of Vienna
Odense University Hospital; Karolinska Institutet; The University of Texas Health... and other collaborators

Completed

Meta-Analysis of Cell-based CaRdiac stUdiEs: ACCRUE (ACCRUE)

Ischemic Heart Disease

Austria
Gdansk University of Physical Education and Sport
University of Brasilia; Jagiellonian University; Klaipėda University; Catholic... and other collaborators

Unknown

Healthy Lifestyle or Pro-health Obsession During the Pandemic

Adult | Global Health

Poland
University Hospital Muenster
Charite University, Berlin, Germany; RWTH Aachen University; Universitätsklinikum... and other collaborators

Completed

Effectiveness of Intensive Aphasia Therapy Under Routine Clinical Conditions (FCET2EC)

Stroke | Aphasia

Germany
Cardiovascular Center Frankfurt
Sheba Medical Center; Kerstin Piayda, CardioVascular Center Frankfurt, Frankfurt... and other collaborators

Active, not recruiting

Therapy Strategies After LAA Occluder Device Embolization (LAAODE)

Risk Factors | Left Atrial Appendage Occluder | Device Embolisation | Therapy Strategies

Germany
University of Jena
Rambam Health Care Campus; Parc de Salut Mar; Charite University, Berlin, Germany and other collaborators

Recruiting

PAIN OUT: Improvement in Postoperative PAIN OUTcome (PAIN-OUT)

Post-operative Pain

Germany
Maastricht University Medical Center
Charles University, Czech Republic; Karolinska University Hospital; Hospices... and other collaborators

Recruiting

European/Euro-ELSO Survey on Adult and Neonatal/ Pediatric COVID-19 Patients in ECMO (EuroECMO-COVID)

Septic Shock | Extracorporeal Membrane Oxygenation | COVID | SARS-CoV-2 | Cardiogenic Shock | ARDS, Human | Refractory Hypoxemia

Spain, Germany, Netherlands, France, Sweden, Belgium, Austria, Portugal, Poland, United Kingdom, Italy, Lithuania, Czechia, Denmark, Greece, Hungary, Israel, Russian Federation, Switzerland

Clinical Trials Sponsored by Leipzig Heart Institute GmbH

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