Clinical Trials Sponsored by Light Sciences Oncology

Total 100 results

Light Sciences Oncology

Completed

Tumor Ablation With Talaporfin Sodium and Interstitial Light Emitting Diodes Treating Hepatocellular Carcinoma (HCC)

Carcinoma, Hepatocellular | Liver Neoplasms

Taiwan, Hong Kong, Singapore
Light Sciences Oncology

Completed

A Phase 3 Study of Talaporfin Sodium and Interstitial Light Emitting Diodes Treating Hepatocellular Carcinoma (HCC)

Carcinoma, Hepatocellular | Liver Neoplasms

Philippines, Korea, Republic of, Singapore, Sweden, Malaysia, India, Serbia, Thailand, Croatia, Hong Kong, Poland
Light Sciences Oncology

Completed

Phase 3 Trial of Litx™ Plus Chemotherapy vs. Chemotherapy Only Treating Colorectal Cancer Patients With Recurrent Liver Metastases

Neoplasm Metastasis | Colorectal Neoplasms | Liver Metastases | Neoplasm Recurrence, Local

Sweden, India, Austria, Serbia, Germany, Romania, Croatia, Bosnia and Herzegovina, Italy, Latvia, Poland, Russian Federation, Ukraine
Light Sciences Oncology

Completed

Phase IIa Safety and Light Dose-escalation Study in Patients With Primary or Recurrent/High-grade Glioma Using the Litx™ System to Confirm the Zone of Tumor Destruction During the Intraoperative Treatment of Glioma

Glioma | Glioblastoma Multiforme | Anaplastic Astrocytoma

Serbia
Light Sciences Oncology

Completed

Phase 1 Study of the Litx™ BPH System in Patients With Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)

Lower Urinary Tract Symptoms | Benign Prostatic Hyperplasia

United States
Light Sciences Oncology

Completed

Study of Light-Activated Talaporfin Sodium in Patients With Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)

Lower Urinary Tract Symptoms | Benign Prostatic Hyperplasia

New Zealand, Australia
Light Sciences Oncology
Mundipharma Research Limited

Completed

A Placebo Controlled Study of MR901 (Talaporfin Sodium Sodium + a Drug-activating Device) for the Relief of Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia

Benign Prostatic Hyperplasia

United States
Light Sciences LLC

Completed

Study to Evaluate the Safety and Efficacy of a Low Level Light Device in Patients With Knee Osteoarthritis

Osteoarthritis, Knee

United States
Light Sciences LLC

Completed

Photodynamic Therapy System for Patients With Refractory/Unresponsive Solid Tumors

Sarcoma | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Rectal Cancer | Pelvic Cancer | Mouth Cancer | Liver Metastasis

United States
ON Light Sciences

Completed

Evaluation of the Safety and Efficacy of the DeScribe™ Patch

Tattoos

United States
Light Sciences LLC

Terminated

Study of Talaporfin Sodium Photodynamic Therapy to Treat Advanced Age Related Macular Disease

Macular Degeneration | Choroidal Neovascularization

United States
Light Sciences LLC

Completed

Study of the Litx™ System Combined With Chemotherapy in Patients With Colorectal Liver Metastases

Neoplasm Metastasis | Liver Neoplasms | Colorectal Neoplasms | Liver Metastasis

United States
Light Sciences LLC

Completed

Photodynamic Therapy With Talaporfin Sodium (LS11) in Treating Patients With Refractory Colorectal Liver Metastases

Neoplasm Metastasis | Liver Neoplasms | Colorectal Neoplasms | Liver Metastasis

United States, Germany
Sight Sciences, Inc.

Completed

A Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System

Glaucoma, Open-Angle

United States
Sight Sciences, Inc.

Completed

An Observational Multicenter Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System In Pseudophakic Eyes With Primary Open Angle Glaucoma (ORION 2.0)

Glaucoma, Open-Angle

United States
Sight Sciences, Inc.

Terminated

A Post-market Study Of Use Of The OMNI® Surgical System In Open Angle Glaucoma

Glaucoma, Open-Angle

United States
Sight Sciences, Inc.

Unknown

TearCare System to Treat Dry Eye Disease (OLYMPIA)

Dry Eye | Meibomian Gland Dysfunction

United States
Sight Sciences, Inc.

Unknown

Study of the TearCare System in Dry Eye Disease

Dry Eye

United States
Sight Sciences, Inc.

Unknown

Pilot Study of the TearCare System

Dry Eye

United States
Sight Sciences, Inc.

Terminated

A Prospective, Multicenter Study of the OMNI® Surgical System in Pseudophakic Eyes With Open Angle Glaucoma (ORION)

Glaucoma, Open-Angle

United States
Sight Sciences, Inc.

Unknown

Pilot Study of TearCare System - Long-Term Extension

Dry Eye Syndromes

United States
Sight Sciences, Inc.

Active, not recruiting

Prospective, Randomized, Masked, Controlled Trial To Evaluate The Safety And Effectiveness Of The TearCare® System In The Treatment Of The Signs And Symptoms Of Dry Eye Disease (SAHARA)

Dry Eye | Meibomian Gland Dysfunction

United States
Sight Sciences, Inc.

Terminated

Study of OMNI Surgical System and iStent for Eyes With OAG (Trident)

Glaucoma, Open-Angle

Germany, Spain, United Kingdom
Sight Sciences, Inc.

Terminated

Randomized Study of the Safety and Effectiveness of the TearCare System for the Signs and Symptoms of Dry Eye Disease

Dry Eye Syndromes

United States
Sight Sciences, Inc.

Unknown

Use of the OMNI® Surgical System in Combination With Cataract Extraction in Open Angle Glaucoma

Open Angle Glaucoma

United States
Sight Sciences, Inc.

Terminated

Randomized Study of the Safety and Effectiveness of the Sight Sciences VISCO™360 Viscosurgical System Versus SLT in Primary Open Angle Glaucoma (VISCO360 Study)

Open-Angle Glaucoma

United States
Philadelphia Fight
Gilead Sciences

Completed

Validation of a Urine Assay to Measure Tenofovir Levels in Patients Taking Tenofovir Alafenamide

Hiv

United States
Tangible Science
Boston Sight

Unknown

Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host Disease

Dry Eye | Stevens-Johnson Syndrome | Sjogren's Syndrome | Graft Versus Host Disease in Eye

United States
Center For Sight
Science in Vision

Completed

Symfony/Synergy IOL Combination Outcomes

Presbyopia | Bilateral Cataract

United States
Center For Sight
Science in Vision

Completed

Synergy Lens Outcomes Evaluation

Presbyopia | Pseudophakia

United States
Ikena Oncology
Gilead Sciences

Terminated

A Study of PY314 in Subjects With Advanced Solid Tumors

Renal Cell Carcinoma | Breast Cancer | Gynecologic Cancer | Colorectal Cancer | Ovarian Cancer | Lung Adenocarcinoma | Triple Negative Breast Cancer | Advanced Solid Tumor | Hormone Receptor/Growth Factor Receptor-Negative Breast Cancer

United States
Ethical Oncology Science

Completed

Phase I Study of the Proteosome Inhibitor CEP 18770 in Patients With Solid Tumours or Non-Hodgkin's Lymphomas

Lymphoma, Non-Hodgkin | Solid Tumors

Switzerland, Italy
Ikena Oncology
Gilead Sciences

Terminated

A Phase 1a/1b FIH Study of PY159 and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

Breast Cancer | Head and Neck Cancer | Gynecologic Cancer | Colorectal Cancer | Pancreatic Cancer | Gastric Adenocarcinoma | Lung Adenocarcinoma | Advanced Solid Tumor

United States
Sunnybrook Health Sciences Centre
Taiho Oncology, Inc.

Terminated

Study of TRIFLURIDINE/TIPIRACIL in Previously Treated Cholangiocarcinoma (MOCHA)

Cholangiocarcinoma | Bile Duct Cancer

Canada
Arcus Biosciences, Inc.
Gilead Sciences; Strata Oncology

Active, not recruiting

Study to Evaluate Safety and Clinical Activity of AB122 in Biomarker Selected Participants With Advanced Solid Tumors

Advanced Solid Tumors

United States
Sunnybrook Health Sciences Centre
Eastern Cooperative Oncology Group

Active, not recruiting

Tomosynthesis Mammographic Imaging Screening Trial (TMISTLead-in)

Breast Cancer

Canada
Strata Oncology
Merck Sharp & Dohme LLC; Pfizer; Gilead Sciences

Recruiting

Strata PATH™ (Precision Indications for Approved Therapies) (Strata PATH)

Cancer | Advanced Solid Tumor

United States
Sunnybrook Health Sciences Centre
Canadian Association of Radiation Oncology

Active, not recruiting

Focal Salvage HDR Brachytherapy for the Treatment of Prostate Cancer

Prostate Cancer

Canada
Sunnybrook Health Sciences Centre
Canadian Association of Radiation Oncology

Completed

Hypofractionated Accelerated Radiotherapy for Low Risk Localized Prostate Cancer (pHART3)

Prostate Cancer

Canada
Sunnybrook Health Sciences Centre
Canadian Association of Radiation Oncology

Completed

Safety and Efficacy Study of Dose-escalated Hypofractionated Radiotherapy For Prostate Cancer (PHART6)

Prostate Cancer

Canada
Tehran University of Medical Sciences
department of radiation oncology

Unknown

COX-2 Inhibitor With Concurrent Chemoradiation in Locally Advanced Head & Neck Carcinoma

Head and Neck Cancer

Iran, Islamic Republic of
Princess Maxima Center for Pediatric Oncology
Innovative Therapies For Children with Cancer Consortium; IBFM; Fight Kids Cancer

Not yet recruiting

HEM-iSMART-B: Dasatinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies (HEM-iSMART B)

Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory | Lymphoblastic...

Netherlands
Princess Maxima Center for Pediatric Oncology
Innovative Therapies For Children with Cancer Consortium; IBFM; Fight Kids Cancer

Not yet recruiting

HEM-iSMART-C: Ruxolitinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies (HEM-iSMART C)

Acute Lymphoblastic Leukemia, in Relapse | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory

Netherlands
Princess Maxima Center for Pediatric Oncology
Innovative Therapies For Children with Cancer Consortium; IBFM; Fight Kids Cancer

Not yet recruiting

HEM-iSMART-A: Decitabine / Venetoclax and Navitoclax in Pediatric Patients With Relapsed or Refractory Hematological Malignancies (HEM-iSMART A)

Acute Lymphoblastic Leukemia, in Relapse | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory

Netherlands
Princess Maxima Center for Pediatric Oncology
Innovative Therapies For Children with Cancer Consortium; IBFM; Fight Kids Cancer

Not yet recruiting

HEM iSMART-D: Trametinib + Dexamethasone + Chemotherapy in Children With Relapsed or Refractory Hematological Malignancies (HEM-iSMART D)

Acute Lymphoblastic Leukemia, in Relapse | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory

Netherlands
Russian Academy of Medical Sciences
Russian Society of Clinical Oncology

Unknown

Neoadjuvant Chemotherapy Docetaxel With or Without SELUMETINIB in Patients With Triple Negative Breast Cancer

Triple Negative Breast Cancer
Hamilton Health Sciences Corporation
McMaster University; Ontario Clinical Oncology Group (OCOG)

Not yet recruiting

Infection Prophylaxis in Total Joint Replacement (PREVENT-iT)

Periprosthetic Joint Infection
Spanish Oncology Genito-Urinary Group
Ipsen; Syntax for Science, S.L

Completed

Spanish Real-World Evidence Cabozantinib (SRWEC)

Renal Cell Carcinoma

Spain
Oregon Health and Science University
Millennium: The Takeda Oncology Company

Completed

Evaluation of Cardiotoxic Effects of Bortezomib

Multiple Myeloma | Heart Failure, Systolic | Cardiotoxins
Sanjay Gandhi Postgraduate Institute of Medical...
American Society of Clinical Oncology

Recruiting

A Randomised Study of Consolidation CTRT Versus Observation After First Line Chemotherapy in Advanced Gallbladder Cancer (RACE-GB)

Gallbladder Cancer Unresectable

India

Clinical Trials Sponsored by Light Sciences Oncology

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Turkmenistan

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Rare Diseases

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