Clinical Trials Sponsored by Lignan Research Inc.

Total 3605 results

Carol Fabian, MD
Lignan Research Inc.

Terminated

Prevention Strategy for Pre-Menopausal Women at High Risk for Development of Breast Cancer

Breast Cancer

United States
Ligand Pharmaceuticals
Medpace, Inc.

Completed

A Comparison Study of the Bioavailability of a Capsule Formulation of LGD-6972 to an Oral Solution Formulation

Type 2 Diabetes Mellitus (T2DM)

United States
Lundbeck LLC
Quintiles, Inc.; ICON Clinical Research; Ligand Pharmaceuticals

Completed

Study to Assess the Safety and Tolerability of Intravenous Carbamazepine in Adults With Epilepsy

Epilepsy

United States
Nucorion Pharmaceuticals, Inc.
Medpace, Inc.; Ligand Pharmaceuticals

Completed

Safety, Tolerability and Pharmacokinetics of NCO-48 Fumarate in Healthy Subjects

Hepatitis B

United States
GlaxoSmithKline
BioClinica, Inc.; Signant Health

Completed

Efficacy and Safety of Mepolizumab in Adults With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)/ Eosinophilic Chronic Rhinosinusitis (ECRS) (MERIT)

Nasal Polyps

Russian Federation, Japan, China
Ligand Pharmaceuticals
CyDex Pharmaceuticals, Inc.

Withdrawn

Comparison of Captisol-Enabled™ Iohexol and Omnipaque™ in Patients With Impaired Renal Function Undergoing Coronary Angiography

Contrast-induced Nephropathy
Nucorion Pharmaceuticals, Inc.
Ligand Pharmaceuticals

Completed

Activity of NCO-48 Fumarate in Treatment-Naive Adults With Chronic Hepatitis B

Chronic Hepatitis B

United States
Ligand Pharmaceuticals
Medpace, Inc.; Beckloff Associates, Inc.

Completed

Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Pharmtechnology LLC
Ligand Research, LLC

Completed

Bioequivalence Study of Two Formulations of Tablets Ramipril 10 mg in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
Efferon JSC
Ligand Research, LLC

Recruiting

Lipopolysaccharide Adsorption (Efferon LPS NEO) in Children With Sepsis (LASSONEO)

Sepsis | Septic Shock

Russian Federation
Efferon JSC
Ligand Research, LLC

Completed

Lipopolisaccharide Adsorption at Septic Shock (LASSO)

Septic Shock

Russian Federation
Pharmtechnology LLC
Ligand Research, LLC

Completed

Bioequivalence Study of Two Formulations of Tablets Ramipril/Hydrochlorothiazide 10 mg/25 mg in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
CyDex Pharmaceuticals, Inc.
Syneos Health; Ligand Pharmaceuticals

Completed

Relative Bioavailability of CE-Iohexol (Captisol-enabled™ Iohexol) Injection and Omnipaque™ Injection

Contrast-induced Nephropathy | Coronary Angiography

Canada
NC Medial Research Inc

Recruiting

A Study of NCS-01 in Patients With Acute Ischemic Stroke

Ischemic Stroke

United States
Dartmouth-Hitchcock Medical Center
Genentech, Inc.; Ligand Pharmaceuticals

Completed

Erlotinib (Tarceva) and Bexarotene (Targretin) Oral Capsules in Advanced Cancers of the Aerodigestive Tract

Advanced, Malignant Aerodigestive Tract Tumor (Lung, Head and Neck and Esophagus)

United States
Dartmouth-Hitchcock Medical Center
Genentech, Inc.; Ligand Pharmaceuticals

Completed

Study of Tarceva and Targretin in Stage I-II Lung Cancer

Carcinoma, Non-small-cell Lung

United States
Signal Relief
Proxima CRO; ITC Imaging, LLC

Completed

Signal Relief Patch in Musculoskeletal Pain

Musculoskeletal Pain

United States
Mebo Research, Inc.
Aurametrix; Menssana Research, Inc.

Completed

Exploratory Study of Volatile Organic Compounds in Alveolar Breath (VOCs)

Nutritional and Metabolic Diseases

United States, United Kingdom
CDA Research Group, Inc.
3VM Research Group, Inc.

Unknown

Assessment of the Safety and Efficacy of 3VM1001 Cream for Treatment of Chronic Pain Caused by Knee Osteoarthritis.

Osteoarthritis of Knee
Athenex, Inc.
TKL Research, Inc.

Completed

Single-Center Study Evaluating Systemic Exposure and Safety of KX2-391 Ointment 1% on the Face or Balding Scalp in Subjects With Actinic Keratosis

Actinic Keratoses

United States
Savara Inc.
INC Research Limited

Completed

Inhaled Vancomycin Tolerability, Safety and Pharmacokinetics

Healthy | Cystic Fibrosis

Australia
Hygieia, Inc
TKL Research, Inc.

Completed

Efficacy and Safety of Frequently Modified Intensive Insulin

Diabetes

United States
Pharmaceutical Research Unit, Jordan
Sanofi-aventis Liban SAL

Withdrawn

COMPOUND (INN): HOE490O - GLIMEPIRIDE / METFORMIN HCl (Amaryl® M)0 (Glimepiride/Metformin Hydrochloride Immediate Release Combination Tablet) in Fed Conditions in Healthy Male and/or Female Subjects.

Healthy

Jordan
Innovaderm Research Inc.

Not yet recruiting

Efficacy, Safety, and Tolerability of Abrocitinib in Subjects With Moderate to Severe Chronic Hand Eczema Refractory to Corticosteroid Therapy

Chronic Hand Eczema

Canada
Innovaderm Research Inc.

Recruiting

Short-Term Efficacy of Triamcinolone Acetonide (Aristocort® C) in Subjects With Atopic Dermatitis

Atopic Dermatitis

Canada
Empower Research Inc

Completed

Exploring Medically Perceived Benefits, Use and Interest in Psychedelics and Cannabinoids (EMPOWER)

Depressive Disorder | Depression | PTSD | Anxiety Disorders | Anxiety | Psychological | Psychedelic Experiences | Psychedelic Drug Dependence

Canada
Lupin Research Inc

Completed

An Open-label, Randomized, 2-Period, Crossover, Pharmacokinetics Study

Pregnancy Prevention

India
Innovaderm Research Inc.

Completed

Development of a Method to Measure mRNA Levels in Skin Samples

Healthy | Psoriasis | Atopic Dermatitis Eczema

Canada
Thorne Research Inc.

Completed

Hemp Oil + User Experience Study

Sleep | Mood | Gastrointestinal Health | General Wellbeing | Physical Discomfort

United States
GLWL Research Inc.

Terminated

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GLWL-01

Diabetes Mellitus, Type 2

United States
Health Research, Inc.

Unknown

The Treatment of Osteoporosis Using a Combination of Teriparatide (Forteo) and Denosumab

Osteoporosis

United States
Musclegen Research, Inc.

Completed

Absorption Comparison on Equivalency Value of Genepro Gen2

Absorption; Disorder, Protein | Analysis, Event History
NEMA Research, Inc.

Withdrawn

Clinical Efficacy and Safety of Axiom Worldwide DRX9000 Axial Decompression System for Treatment of Low Back Pain

Low Back Pain

United States
NEMA Research, Inc.

Completed

Prevalence of Potential Cytochrome P450 Pharmacokinetic Incident Drug-Drug Interactions(DDI) Among Osteoarthritis Patients

Osteoarthritis
Vitality in Aging Research Group, Inc.

Withdrawn

VIAging Deceleration Trial Using Metformin, Dasatinib, Rapamycin and Nutritional Supplements

Aging
NEMA Research, Inc.

Not yet recruiting

ENA-001 for Post Operative Respiratory Depression (PORD)

Respiratory Depression
Innovaderm Research Inc.

Recruiting

Collection of Samples From Subjects With Various Skin Conditions and Healthy Volunteers

Plaque Psoriasis | Atopic Dermatitis | Hidradenitis Suppurativa | Palmoplantar Pustulosis | Acne | Chronic Hand Eczema

Canada
Innovaderm Research Inc.

Recruiting

Study to Assess the Reliability of PASI Scoring Using Digital-Based Images

Plaque Psoriasis

Canada
Innovaderm Research Inc.

Recruiting

Effects of Abrocitinib in Subjects With Atopic Dermatitis With an Unsatisfactory Response After Treatment With Dupilumab

Atopic Dermatitis

Canada, United States
NEMA Research, Inc.

Recruiting

Ketorolac Applied by Continuous IV Infusion for Treatment of Moderately Severe Postoperative Pain Following Bunionectomy

Pain, Postoperative

United States
Innovaderm Research Inc.

Completed

Inflammatory Cells From Various Pathologies

Acne Vulgaris | Atopic Dermatitis | Acne Rosacea

Canada
Thorne Research Inc.

Completed

Nutraceutical Supplement in the Management of Hypertension

Hypertension

United States
PharPoint Research, Inc.

Withdrawn

Study to Evaluate Phenobarbital Sodium Injection for the Treatment of Neonatal Seizures

Neonatal Seizure
PRCL Research Inc.

Completed

A Study of PRCL-02 in Healthy Volunteers and Plaque Psoriasis

Psoriasis

Canada
Innovaderm Research Inc.

Terminated

Etanercept in Rheumatoid Arthritis and Vascular Inflammation

Rheumatoid Arthritis | Vascular Inflammation

Canada
Innovaderm Research Inc.

Completed

Effect of RANKL Inhibition on UV-induced Immunosuppression

Hypersensitivity, Delayed | Immunosuppression | Ultraviolet Rays | Immune Tolerance/Drug Effects

Canada
NEMA Research, Inc.

Completed

Prevalence of Potential Cytochrome P450 Pharmacokinetic Incident Drug-Drug Interactions Among Chronic Low Back Pain Patients Taking Opioid Analgesics and Associated Economic Outcomes

Chronic Low Back Pain
Chakshu Research, Inc.

Completed

An Open-Label Study of an Ophthalmic Solution to Reduce Intraocular Pressure in Patients With Ocular Hypertension

Ocular Hypertension

United States
Chakshu Research, Inc.

Unknown

An Open-Label Study of the Effect of an Ophthalmic Solution on Asteroid Hyalosis

Asteroid Hyalosis

United States
Chakshu Research, Inc.

Unknown

Dose-Ranging Study of an Ophthalamic Solution in Patients With Loss of Visual Function Due to Age-Related Nuclear Cataract

Nuclear Cataract

Nepal

3

Subscribe