Clinical Trials Sponsored by Malaria Alert Centre

Total 598 results

Centers for Disease Control and Prevention
Malaria Alert Centre

Completed

Text Message Reminders to Health Workers on Malaria, Pneumonia, and Diarrhea Case Management in Malawi

Pneumonia | Diarrhea | Malaria
Clinical Research Centre, Malaysia
University of Malaya

Completed

Factors Associated With Poor Dengue Outcomes in Malaysia

Dengue Fever

Malaysia
Clinical Research Centre, Malaysia
University of Malaya; Ministry of Health, Malaysia

Recruiting

The Effect of SGLT-2 Inhibitors on Epicardial Adipose Tissue and Cardiac Function in T2DM Patients With CAD (EpiCAD) (EpiCAD)

Coronary Artery Disease

Malaysia
Centre d'Appui à la lutte contre la Maladie
World Health Organization; Malaria Research and Training Center, Bamako, Mali

Completed

Impact of Albendazole -Ivermectin on Wuchereria Bancrofti in Mali

Lymphatic Filariasis
Medicines for Malaria Venture

Completed

A Dose-escalation Study to Investigate Safety and Toleration of OZ439

Malaria

United Kingdom
Medicines for Malaria Venture

Completed

Piperaquine Granule Formulation Relative Bioavailability and Food Effect Study in Healthy Volunteers. (PedPQP(BA/FE))

Malaria

Tanzania
Medicines for Malaria Venture

Completed

Absolute BA and OZ439 PK Effect of Different OZ439 Dose Volumes and Cobicistat Co-administration Study

Malaria

Netherlands
Medicines for Malaria Venture

Completed

OZ439 PhIIa Study in Plasmodium Falciparum: Extended Observation

Malaria

Thailand
Medicines for Malaria Venture

Completed

A Comparison of the Bioavailability of OZ439 When Delivered Directly to the Small Intestine, or Via the Oral Route

Healthy Volunteers

United Kingdom
Medicines for Malaria Venture

Completed

Phase II Efficacy Study of Artefenomel & Piperaquine in Adults & Children With P. Falciparum Malaria.

Uncomplicated Plasmodium Falciparum Malaria

Uganda, Benin, Burkina Faso, Congo, The Democratic Republic of the, Gabon, Mozambique, Vietnam
Medicines for Malaria Venture

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of OZ439 in Healthy Male and Female Subjects

Healthy Volunteers | Malaria Falciparum | Malaria Vivax

United States
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Study to Assess the Incidence of Hemolysis, Safety, and Efficacy of Tafenoquine (SB-252263, WR238605) Versus Primaquine in Subjects With Plasmodium Vivax Malaria

Malaria, Vivax

Thailand, Vietnam, Colombia, Brazil, Ethiopia, Peru
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Ph 2B/3 Tafenoquine (TFQ) Study in Prevention of Vivax Relapse

Malaria, Vivax

Thailand, India, Brazil, Ethiopia, Peru, Bangladesh, Cambodia, Philippines
Medicines for Malaria Venture
AbbVie

Terminated

Bioavailability and Effect of Food on DSM265 Granules in Healthy Adult Subjects

Healthy Volunteers | Bioavailability

United States
Malaria Vaccine and Drug Development Center

Not yet recruiting

Efficacy of a Synthetic Vaccine Derived From Plasmodium Vivax Circumsporozoite Protein (PvCS) in naïve and Semi-immune Volunteers

Malaria, Vivax

Colombia
Sanofi
Medicines for Malaria Venture

Terminated

To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of a Single Dose Regimen of Ferroquine and Artefenomel in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria (FALCI)

Plasmodium Falciparum Infection

Benin, Burkina Faso, Gabon, Kenya, Mozambique, Uganda, Vietnam
GlaxoSmithKline
Medicines for Malaria Venture

Completed

A Pharmacokinetics, Safety and Efficacy Study of Tafenoquine (TQ) in Pediatric Subjects With Plasmodium Vivax (P. Vivax) Malaria

Malaria, Vivax

Vietnam, Colombia
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Single-Blind, Placebo-Controlled, Randomized Study Testing Single Ascending Doses Of GSK369796 In Healthy Subjects

Malaria

United Kingdom
Sanofi
Medicines for Malaria Venture

Completed

Artesunate Plus Amodiaquine in Malaria in Cote d'Ivoire

Malaria

Côte D'Ivoire
GlaxoSmithKline
Medicines for Malaria Venture

Recruiting

A Study to Investigate the Safety of GSK4024484 in Healthy Adult Participants

Malaria, Falciparum

United Kingdom
Sanofi
Medicines for Malaria Venture

Completed

Study to Investigate the Clinical and Parasiticidal Activity and Pharmacokinetics of Different Doses of Artefenomel and Ferroquine in Patients With Uncomplicated Plasmodium Falciparum Malaria

Plasmodium Falciparum Infection

Benin, Burkina Faso, Gabon, Kenya, Uganda
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Efficacy and Safety Study of Tafenoquine (TQ) Co-administered With Dihydroartemisinin-piperaquine (DHA-PQP) for the Radical Cure of Plasmodium Vivax (P. Vivax) Malaria

Malaria, Vivax

Indonesia
Medicines for Malaria Venture
AbbVie

Completed

Malaria: Relative Bioavailability and Food Effect of DSM265

Healthy Volunteers

United States
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Assessment of Any Potential Retinal Effects of Tafenoquine (TQ)

Malaria, Vivax

United States
GlaxoSmithKline
Medicines for Malaria Venture

Completed

A Study to Evaluate the Pharmacokinetics of a Single Dose of Tafenoquine Co-administered With Either Artemether + Lumefantrine or Dihydroartemisinin + Piperaquine Tetraphosphate

Malaria, Vivax

United States
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Tafenoquine/Chloroquine DDI Study

Malaria

United States
GlaxoSmithKline
Medicines for Malaria Venture

Completed

G6PD (Glucose-6-phosphate Dehydrogenase) Study to Evaluate Hemolysis Potential of TFQ (Tafenoquine)

Malaria

Thailand
GlaxoSmithKline
Parexel; Medicines for Malaria Venture

Completed

A Study to Assess the Effects of Dissolution Profile on the Pharmacokinetics of Single Oral Doses of Tafenoquine Tablets and Tafenoquine Stable Isotope Labelled Solution

Malaria, Vivax

United States
Medicines for Malaria Venture
Quotient Clinical

Completed

Bioavailability Study of Oral OZ439 Prototype Granule Formulations Administered With Piperaquine Phosphate (PQP) Tablets

Malaria

United Kingdom
Clinical Research Centre, Malaysia
University Malaysia Sarawak

Completed

Effectiveness of an Intervention in Improving Medication Adherence Among Malay Patients With Underlying Type 2 Diabetes Mellitus in Malaysia (MedAdh-RCT)

Type 2 Diabetes Mellitus | Medication Adherence

Malaysia
Clinical Research Centre, Malaysia

Recruiting

Real World COVID-19 Antiviral Effectiveness Research (myRECOVER)

COVID-19

Malaysia
Universiti Sains Malaysia
Clinical Research Centre, Malaysia; Malaysia Palm Oil Board

Withdrawn

Modulating Effects of Oil Palm Phenolics in Subjects With Pre-diabetes (PREDOPP)

Prediabetes

Malaysia
Universiti Sains Malaysia
Clinical Research Centre, Malaysia; Malaysia Palm Oil Board

Terminated

Modulating Effects of Oil Palm Phenolics in Uncontrolled Insulin-treated Type 2 Diabetes Mellitus (UNIDOPP)

Uncontrolled Insulin-treated Type 2 Diabetes Mellitus

Malaysia
Universiti Sains Malaysia
Clinical Research Centre, Malaysia; Malaysia Palm Oil Board

Completed

Neuroprotection by Tocotrienols in Type 1 and Type 2 Diabetes Mellitus (VENUS)

Cognitive Impairment | Diabetic Neuropathy

Malaysia
Clinical Research Centre, Malaysia
Ministry of Health, Malaysia

Completed

Effectiveness of PICC Improving HBA1C and Knowledge in Diabetes Mellitus Education (EPICCIHKDMEP)

Diabetes Mellitus | Type2 Diabetes

Malaysia
Clinical Research Centre, Malaysia
Hospital Queen Elizabeth, Malaysia

Terminated

Risk Factors for Mortality for COVID-19 Admitted to an Intensive Care Unit (ICUCOVID-KK)

Covid19 | Critically Ill

Malaysia
Clinical Research Centre, Malaysia
Ministry of Health, Malaysia

Unknown

Efficacy and Safety of Cholestyramine and Prednisolone as Adjunctive Therapy in Treatment of Overt Hyperthyroidism (ChoPS)

Graves Disease | Hyperthyroidism

Malaysia
Medicines for Malaria Venture
Quotient Clinical

Completed

Bioavailability Study of Oral OZ439 Prototype Formulations Administered With Piperaquine Phosphate (PQP)

Malaria

United Kingdom
Medicines for Malaria Venture
Mahidol University

Completed

Efficacy, Tolerability, PK of OZ439 in Adults With Acute, Uncomplicated P.Falciparum or Vivax Malaria Mono-infection

Malaria, Falciparum | Malaria, Vivax
Treague Ltd
Medicines for Malaria Venture

Completed

Study to Investigate the Safety, Tolerability and Pharmacokinetics of AD 452 [(+)-Mefloquine] Compared With Racemic Mefloquine

Healthy Subjects

United Kingdom
Boston University
National Institute of Allergy and Infectious Diseases (NIAID); Burnet Institute and other collaborators

Recruiting

COVID-19 Transmission and Morbidity in Malawi (COVID-TMM)

SARS CoV 2 Infection | SARS CoV 2 Vaccination

United States, Malawi
Radboud University Medical Center
Leiden University Medical Center; Medicines for Malaria Venture

Withdrawn

Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine or Chloroquine/Azithromycin Prophylaxis (MMV)

Malaria, Falciparum

Netherlands
Clinical Research Centre, Malaysia
University of Malaya; London School of Economics and Political Science; Ministry... and other collaborators

Completed

Health Communication to Influence COVID-19 Vaccination Intent and Message Propagation (CONVINCE)

Coronavirus Infections | Respiratory Tract Infections | COVID-19 | Pneumonia, Viral | Pneumonia | Lung Diseases | Infectious Disease | Respiratory Disease | Behavior, Health | Vaccine Refusal

Malaysia
Clinical Research Centre, Malaysia

Not yet recruiting

Early Intravenous to Oral Antibiotic Switch in Uncomplicated Staphylococcus Aureus Bacteraemia (EVOS)

Staphylococcus Aureus Bacteremia

Malaysia
Clinical Research Centre, Malaysia

Recruiting

Virtual Reality for Generalized Anxiety Disorders (VR-GAD)

Generalized Anxiety Disorder

Malaysia
Clinical Research Centre, Malaysia

Recruiting

Efficacy of PC6 Electroacupuncture in the Prevention of Nausea Vomiting in Caesarean Patient Under Spinal Anaesthesia

Postoperative Nausea and Vomiting

Malaysia
Clinical Research Centre, Malaysia

Completed

Ivermectin Treatment Efficacy in Covid-19 High Risk Patients (I-TECH)

COVID-19

Malaysia
Clinical Research Centre, Malaysia

Unknown

A Panel of Biomarkers in Diagnosing Late-onset Neonatal Sepsis and Necrotizing Enterocolitis in Sibu Hospital (PISALONS)

Necrotizing Enterocolitis | Neonatal SEPSIS

Malaysia
Clinical Research Centre, Malaysia

Completed

High Strong Ion Difference Fluid vs Hartmann's Solution on Acid-Base Status in Sepsis (HiSIDSS)

Septicemic Shock
Clinical Research Centre, Malaysia

Completed

The Clinical Epidemiology of Hospitalized Dengue Cases in Malaysia

Dengue Fever

Malaysia

Clinical Trials Sponsored by Malaria Alert Centre

Sponsors and Collaborators

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