Clinical Trials Sponsored by Mateon Therapeutics

Total 6917 results

Mateon Therapeutics

Completed

Rollover Protocol for Subjects Who Have Responded on Study 4218s - A Phase 2 Study

Neuroendocrine Tumors

United States
Mateon Therapeutics

Terminated

FOCUS: PCC + Bevacizumab + CA4P Versus PCC + Bevacizumab + Placebo for Subjects With Platinum Resistant Ovarian Cancer

Platinum Resistant Ovarian Cancer

United States, Belgium, Germany
Mateon Therapeutics

Withdrawn

Fosbretabulin or Placebo in Combination With Carboplatin/Paclitaxel in Anaplastic Thyroid Cancer (FACT2)

Anaplastic Thyroid Cancer
Mateon Therapeutics

Completed

Safety and Efficacy Study of Combretastatin A4 Phosphate to Treat Patients With Choroidal Neovascularization Secondary to Pathologic Myopia

Choroidal Neovascularization | Myopia, Degenerative
Mateon Therapeutics

Completed

Safety and Effectiveness of Combretastatin A-4 Phosphate Combined With Chemotherapy in Advanced Solid Tumors

Cancer | Tumor

United States
Mateon Therapeutics

Completed

A Safety and Efficacy Study of Carboplatin, Paclitaxel, Bevacizumab and CA4P in Non-Small Cell Lung Cancer (FALCON)

Tumors

United States
Mateon Therapeutics

Completed

Study Evaluating the Safety and Response of Fosbretabulin in Asian Patients With Polypoidal Choroidal Vasculopathy (PCV)

Polypoidal Choroidal Vasculopathy

United States, Hong Kong, Korea, Republic of, Singapore, Taiwan
Mateon Therapeutics

Completed

Safety Study of Increasing Doses of Combretasatin A1 Diphosphate (OXi4503) as Monotherapy in Subjects With Hepatic Tumor Burden (OXi4503)

Neoplasm Metastasis

Australia
Mateon Therapeutics

Unknown

Dose Escalation of OXi4503 as Single Agent and Combination With Cytarabine w/Subsequent Ph 2 Cohorts for AML and MDS (AML)

Myelodysplastic Syndromes | Acute Myelogenous Leukemia

United States
Mateon Therapeutics

Completed

A Ph 2 Study of Fosbretabulin in Subjects w Pancreatic or Gastrointestinal Neuroendocrine Tumors w Elevated Biomarkers (GI-NETorPNET)

Neuroendocrine Tumors

United States
Mateon Therapeutics

Terminated

Study of Combretastatin and Paclitaxel/Carboplatin in the Treatment of Anaplastic Thyroid Cancer (FACT)

Anaplastic Thyroid Cancer

United States, India, Belarus, Bulgaria, Egypt, Israel, Italy, Poland, Romania, Russian Federation, Ukraine, United Kingdom
Mateon Therapeutics

Completed

Safety Study of Increasing Doses of Combretastatin in Combination With Bevacizumab (Avastin) in Patients With Advanced Solid Tumors

Tumors

United Kingdom
Oncotelic Inc.

Not yet recruiting

A Study of OT-101 With mFOLFIRINOX in Patients With Advanced and Unresectable or Metastatic Pancreatic Cancer (STOP-PC)

Pancreatic Ductal Adenocarcinoma
Oncotelic Inc.

Not yet recruiting

A Study to Evaluate the Safety and Efficacy of OT-101+Artemisinin in Hospitalized COVID-19 Subjects

COVID-19

Brazil
Oncotelic Inc.

Not yet recruiting

OT-101 in Combination With Pembrolizumab in Subjects With Malignant Pleural Mesothelioma Failing to Respond to Checkpoint Inhibition

Malignant Pleural Mesothelioma

United States
Mateon Therapeutics
Cancer Research UK

Completed

Safety Study of OXi4503 (a Vascular Disrupting Agent) Given by 3 x Weekly Intravenous Infusions to Patients With Advanced Solid Tumors

Solid Tumors

United Kingdom
Mateon Therapeutics
Windlas Biotech Private Limited

Completed

A Study to Evaluate the Safety and Efficacy of Artemisinin- a Herbal Supplement on COVID-19 Subjects

Covid19

India
Henry Aristoteles Mate-Sánez

Completed

Misoprostol as a Treatment for Endometrial Polyps in Infertile Patients

Endometrial Polyps in Infertile Patients
Cancer Research UK
Teon Therapeutics, Inc.

Recruiting

TT-702 in Patients With Advanced Solid Tumours. (CURATE)

Advanced Solid Tumors

United Kingdom
Ramón Mateos Alpuente

Recruiting

Effects of an Osteopathic Treatment Protocol on Sleep Quality

Sleep Disorder

Spain
The Christie NHS Foundation Trust
Novartis; East and North Hertfordshire NHS Trust; Mateon Therapeutics

Terminated

PAZOFOS: Phase Ib and Phase II Trial of Pazopanib +/- Fosbretabulin in Advanced Recurrent Ovarian Cancer (PAZOFOS)

Ovarian Neoplasms | Ovarian Cancer | Neoplasms, Ovarian

United Kingdom
HALEON

Recruiting

Clinical Study to Evaluate the Anti-sensitivity Efficacy of a Stannous Fluoride Toothpaste in a Population of Dentin Hypersensitivity Sufferers

Dentin Sensitivity

United States
HALEON

Not yet recruiting

A Study to Evaluate the Effect of a Stannous Fluoride Toothpaste on the Oral Microbiome

Oral Health
HALEON

Completed

Clinical Study to Investigate the Tooth Stain Removal Efficacy of Two Experimental Toothpastes Compared to a Standard Toothpaste When Used Twice Daily for 8 Weeks

Oral Hygiene

United States
HALEON

Active, not recruiting

A Study Assessing the Effects of an Experimental Dentifrice in Maintaining Tooth Color Following Tooth Bleaching

Oral Hygiene | Dentin Sensitivity

United States
HALEON

Completed

A Clinical Study to Evaluate the Efficacy of a Stannous Fluoride Dentifrice in the Relief of Dentinal Hypersensitivity in a Chinese Population

Dentin Sensitivity

China
HALEON

Completed

A Clinical Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste for the Relief of Dentine Hypersensitivity in a Chinese Population

Dentin Sensitivity

China
HALEON

Completed

A Bioequivalence Study of Two Ibuprofen Arginine Granules 400 mg Formulations Under Fasting and Fed Conditions in Chinese Healthy Adult Subjects

Pain

China
HALEON

Completed

A Bioequivalence Study of Advil PM Liqui-Gels Minis (Ibuprofen/Diphenhydramine Hydrochloride 200 mg/25 mg) Compared to the Current Marketed Advil PM Liqui-Gels (Ibuprofen/Diphenhydramine Hydrochloride 200 mg/25 mg) in Healthy Adult Subjects Under Fasted Conditions

Pain

United States
HALEON

Completed

Otrivine: Quality of Life (QoL) Impact in a Real-World Setting

Common Cold

United Kingdom
HALEON

Completed

Clinical Study to Evaluate the 80-Minute Water Resistant Sun Protection Factor (SPF) of Sunscreen Products

Sunscreening Agents

United States
Hospital Mateo Orfila

Completed

Metabolic Syndrome and Leptin Level Associated With Fructose Consumption in Spain

Healthy

Spain
Teon Therapeutics, Inc.
Merck Sharp & Dohme LLC

Terminated

TT-816 as Monotherapy or in Combination With a PD-1 Inhibitor in Patients With Advanced Cancers (SEABEAM) (MK3475-E88)

Cancer | Advanced Solid Tumor | Advanced Cancer | Oncology

United States
Hospital Mateo Orfila

Completed

The Effect of Allopurinol on Insulin Resistance and Blood Pressure

Metabolic Syndrome

Spain
HALEON

Not yet recruiting

A Clinical Study to Evaluate the Anti-Sensitivity Efficacy of a Stannous Fluoride Toothpaste in a Population of Dentin Hypersensitivity Sufferers

Dentin Sensitivity

United States
HALEON

Completed

Clinical Study to Evaluate the Sun Protection Factor (SPF) of Sunscreen Products

Sunscreening Agents

United States
HALEON

Completed

Bioequivalence Study of Esomeprazole 20 Milligram (mg) Delayed-Release Capsules in Healthy Adult Participants

Gastrointestinal Diseases

Canada
HALEON

Active, not recruiting

A Real-World Evidence Study Evaluating Oral Health Related Quality Of Life With Use Of A Stannous Fluoride Anti-Sensitivity Toothpaste For Dentin Hypersensitivity Management

Dentin Sensitivity

United States
HALEON

Completed

A Clinical Study to Examine the Effects of an Experimental Toothpaste Compared to a Regular Fluoride Toothpaste on Breath Odor in a Population With Gingivitis

Halitosis

United States
HALEON

Completed

Exploratory Clinical Study to Investigate the Ability of an Experimental Combination Dentifrice to Protect Sensitive Teeth

Dentin Sensitivity

United Kingdom
Therapeutic Neuroscience Research Group
Rockhurst University; Evidence in Motion

Active, not recruiting

Immediate Effects of a 10-minute Body Scan Meditation on People Who Has Central Sensitization

Chronic Pain

United States
HALEON

Completed

Clinical Study to Evaluate the Efficacy of an Over-the-counter (OTC) Sunscreen Lip Balm Product

Sunscreening Agents

United States
HALEON

Completed

A Clinical Study Investigating the Effects of a Dentifrice Containing 0.454% Stannous Fluoride on Gingivitis Treatment and Plaque Reduction When Used Twice Daily for 12 Weeks

Gingivitis

United States
HALEON

Completed

A Bioequivalence Study of 21 Milligram (mg) Nicotine Transdermal Patches (NicoDerm CQ, GlaxoSmithKline [GSK] Dungarvan) Compared to the Current Marketed 21 mg Nicotine Transdermal Patches (NicoDerm CQ, Alza) in Healthy Adult Smokers

Tobacco Use Disorder

United States
HALEON

Active, not recruiting

An Erosion Study to Investigate the Efficacy of an Experimental Dentifrice to Remineralize Enamel

Tooth Erosion

United States
HALEON

Completed

A Bioequivalence Study of a New Paracetamol Oral Suspension 24mg/ml Compared to the Marketed Paracetamol Oral Suspension (Panadol Baby and Infant 24mg/ml) in Healthy Adult Subjects

Pain

Czechia
HALEON

Completed

A Clinical Study to Evaluate the Maximum Maxillary Bite Force (BF) When Using Two Novel Denture Adhesives Compared to Using No-Adhesive

Denture Retention

United States
HALEON

Completed

A Real-World Evidence Study to Evaluate Oral Health Related Quality of Life Using an Anti-Sensitivity Toothpaste

Dentin Sensitivity

United States
HALEON

Completed

A Clinical Study Investigating the Effects of a Dentifrice Containing 67% Sodium Bicarbonate When Used Twice Daily for 12 Weeks on Gingivitis Treatment and Plaque Removal

Gingivitis | Dental Plaque

United Kingdom
HALEON

Completed

A Clinical Study to Evaluate the Efficacy of a Range of Dental/Denture Products for Improved Oral Health in Partial Denture Wearers

Gingivitis

United Kingdom

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