Clinical Trials Sponsored by Medolution Ltd.

Total 16858 results

Medolution Ltd.

Recruiting

Phase Ib Clinical Study of Keynatinib

Lymphoma, B-Cell

China
Medolution Ltd.

Recruiting

Keynatinib in Treated Patients With NSCLC and Brain Metastases

Brain Metastases | Non-Small Cell Lung Cancer With EGFR Mutation

China
Resolution Therapeutics Limited

Recruiting

Study in Patients With Decompensated Liver Cirrhosis (OPAL)

Liver Cirrhosis

United Kingdom
Revolution Medicines, Inc.

Recruiting

Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors

Advanced Solid Tumor | Pancreatic Ductal Adenocarcinoma | Non-Small Cell Lung Cancer (NSCLC) | Colorectal Cancer (CRC)

United States, Italy, Spain, Malaysia, Korea, Republic of, France, Australia, Thailand, Taiwan, Poland, Singapore, Czechia, Serbia
Symphony Evolution, Inc.

Terminated

Study of XL999 in Patients With Metastatic Colorectal Cancer

Colorectal Cancer

United States
Revolution Medicines, Inc.

Recruiting

Study of RMC-6291 in Combination With RMC-6236 in Participants With Advanced KRAS G12C Mutant Solid Tumors

Colorectal Cancer | Pancreatic Ductal Adenocarcinoma | Non-Small Cell Lung Cancer (NSCLC)

United States
Revolution Medicines, Inc.

Recruiting

Study of RMC-9805 in Participants With KRASG12D-Mutant Solid Tumors

Advanced Solid Tumors | Non-small Cell Lung Cancer (NSCLC) | Pancreatic Ductal Adenocarcinoma (PDAC) | Colorectal Cancer (CRC)

United States
Symphony Evolution, Inc.

Terminated

Study of XL999 in Patients With Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia | AML

United States
Symphony Evolution, Inc.

Completed

Study of XL999 in Adults With Solid Tumors

Cancer

United States
Symphony Evolution, Inc.

Terminated

Study of XL999 in Patients With Metastatic Renal Cell Carcinoma

Renal Cell Carcinoma

United States
Symphony Evolution, Inc.

Terminated

Safety Study of XL999 in Adults With Non-Small-Cell Lung Cancer

Non-Small-Cell Lung Cancer

United States
Revolution Medicines, Inc.
Sanofi

Completed

Dose-Esc/Exp RMC4630 & Cobi in Relapsed/Refractory Solid Tumors & RMC4630& Osi in EGFR+ Locally Adv/Meta NSCLC

Solid Tumor

United States, Korea, Republic of
Revolution Medicines, Inc.

Recruiting

Study of RAS(ON) Inhibitor Combinations in Patients With Advanced RAS-mutated NSCLC

Non-Small Cell Lung Cancer, NSCLC | KRAS, NRAS, HRAS-mutated NSCLC | KRAS G12C-mutated Solid Tumors, Lung Cancer | Lung Cancer Stage IV, Advanced Solid Tumor, Cancer

United States
Revolution Medicines, Inc.

Recruiting

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

Advanced Solid Tumors | Non-small Cell Lung Cancer (NSCLC) | Pancreatic Ductal Adenocarcinoma (PDAC) | Colorectal Cancer (CRC)

United States
Revolution Medicines, Inc.

Active, not recruiting

Dose Escalation of RMC-5552 Monotherapy in Relapsed/Refractory Solid Tumors

Solid Tumors

United States
Revolution Medicines, Inc.
Sanofi; Amgen

Active, not recruiting

Combination Study of RMC-4630 and Sotorasib for NSCLC Subjects With KRASG12C Mutation After Failure of Prior Standard Therapies

Non-Small Cell Lung Cancer

United States, Korea, Republic of, Canada, Taiwan, Spain, United Kingdom, Italy, Australia, France, Germany
Evolution Optiks Limited

Completed

LFR-260 vs Traditional Phoropter in Visual Acuity Testing

Astigmatism | Visual Acuity | Anisometropia

United States
Applied Molecular Evolution

Completed

Safety and Efficacy Study of an Anti-CD20 Monoclonal Antibody (AME-133v) to Treat Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma

United States
Symphony Evolution, Inc.

Completed

Maintenance Study on the Long Term Safety of XL999

Advanced Malignancies

United States
Symphony Evolution, Inc.

Completed

Study of XL784 in Patients With Albuminuria Due to Diabetic Nephropathy

Diabetic Nephropathy | Albuminuria

United States
Symphony Evolution, Inc.

Terminated

Study of XL999 in Patients With Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

United States
Symphony Evolution, Inc.

Terminated

Study of XL999 in Patients With Multiple Myeloma

Multiple Myeloma

United States
Symphony Evolution, Inc.

Terminated

Study of XL999 in Patients With Previously Treated Ovarian Cancer

Ovarian Cancer

United States
Revolution Medicines, Inc.
Sanofi

Active, not recruiting

Dose Escalation of RMC-4630 Monotherapy in Relapsed/Refractory Solid Tumors

Solid Tumors

United States
Revimmune
C.R.O. ReSolution Latin America S.A.

Terminated

InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection (Brazil Cohort) (ILIAD-7-BRA)

COVID-19 | Lymphocytopenia

Brazil
Applied Molecular Evolution
Eli Lilly and Company

Completed

A Phase 1 Safety Study of LY2127399 in Combination With Bortezomib

Multiple Myeloma

United States
Resolution Blue Labs Inc
Heartfulness Institute

Recruiting

Heartfulness Meditation and Corporate Burnout

Stress | Burnout | Meditation | Heartfulness

Canada
Luye Pharma Group Ltd.
Alliance for Clinical Trials in Oncology; Evolution Research Group

Completed

Evaluate the PK of LY03010 Process 1 and Process 2 Drug Product vs INVEGA SUSTENNA After Intramuscular Injection in Schizophrenia Patients

Schizophrenia Patients

United States
Sanofi
Mirati Therapeutics Inc.; Revolution Medicines, Inc.

Active, not recruiting

Safety and Efficacy Study of SAR442720 in Combination With Other Agents in Advanced Malignancies

Metastatic Neoplasm

Taiwan, Chile, Korea, Republic of, United States, Argentina, Australia, Netherlands, Spain
Nicholas Butowski
National Cancer Institute (NCI); Revolution Medicines, Inc.

Recruiting

RMC-5552 Monotherapy in Adult Subjects With Recurrent Glioblastoma

Glioblastoma | Recurrent Glioblastoma

United States
Mirka Ltd
Clinius Ltd

Completed

A Pre-market Study to Evaluate the Performance and Safety of a Skin Preparation Device for Removal of Dry Crusty Skin

Keratosis, Actinic | Hyperkeratotic Callus | Actinic Lesion | Solar Keratosis/Sunburn | Hyperkeratosis | Hyperkeratotic; Lesion | Hyperkeratotic Actinic Keratosis

Finland
Pharmaxis
ethica Clinical Research Inc.; Europe: KasaConsult bvba, Hoegaarden, Belgium; Argentina: Resolution Latin America; Buenos Aires, Argentina

Completed

Long Term Administration of Inhaled Mannitol in Cystic Fibrosis

Cystic Fibrosis

United States, France, Belgium, Canada, Argentina, Germany, Netherlands
Salus Ltd.
TheraVitae Ltd.

Completed

Autologous Angiogenic Cell Precursors (ACPs) for the Treatment of Peripheral Artery Disease

Critical Limb Ischemia

Hungary
Janssen-Cilag Farmaceutica Ltda.
Janssen Korea, Ltd., Korea

No longer available

An Expanded Access Program for Decitabine in Patients With Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndromes

Hong Kong, Brazil, Thailand
Paion UK Ltd.
Chiltern International Ltd.; HFL Ltd.

Completed

An Efficacy and Safety Study to Compare Morphine 6-glucuronide (M6G) and Morphine in Patients Suffering With Post-Operative Pain for at Least 24 Hours

Postoperative Pain

France, Germany, Netherlands, Poland, United Kingdom, Czechia
Calcivis Ltd
Medsource UK Ltd.

Completed

Caries Lesion Activity in Orthodontic Patients - Calcivis System

Dental Caries

United Kingdom
Cardiovalve Ltd.
Meditrial Europe Ltd.

Recruiting

Cardiovalve Transfemoral System - FIM Study

Mitral Regurgitation

Lithuania
Vensica Therapeutics Ltd.
Blueclinical, Ltd.

Completed

Clinical Trial for the Assessment of Safety, Usability and Efficacy of the Vixe Combination for OAB in Female Subjects (XAVIER)

Overactive Bladder

Portugal
Nanomedic Technologies Ltd.

Completed

Evaluation of the SpinCare™ System in the Treatment of Partial Thickness Burns (SPINCARE2)

Partial Thickness Burn

Israel
Nanomedic Technologies Ltd.

Completed

Evaluation of the SPINNER Device for the Application of Wound Dressing: Treatment of Split Skin Graft Donor Sites (SPINNER01)

Wound of Skin

Israel
Danisco
4Pharma Ltd.; Medfiles Ltd.

Completed

Next Generation Probiotics (NGPs) for Metabolic Health

Microbial Colonization
Calcivis Ltd
Medsource UK Ltd.

Completed

Safety and Performance Evaluation of the Calcivis System

Dental Caries

United Kingdom
Targia Pharmaceuticals Ltd.
SoluBest Ltd.

Unknown

Comparative Bioavailability Study of Omexa Sumatriptan vs. Imitrex® in Healthy Volunteers

Migraine
Xention Ltd
Ario Pharma Ltd

Completed

A Study to Assess the Efficacy of XEN-D0501 in Reducing the Cough Frequency in Patients With COPD

Chronic Obstructive Pulmonary Disease

United Kingdom
TyrNovo Ltd.

Active, not recruiting

A Study to Evaluate NT219 Alone and in Combination With ERBITUX® (Cetuximab) in Adults With Advanced Solid Tumors and Head and Neck Cancer

Head and Neck Cancer | Squamous Cell Carcinoma of Head and Neck | Metastatic Solid Tumor | Colorectal Adenocarcinoma | Solid Tumor, Adult | Recurrent Solid Tumor

United States, Israel
Xention Ltd
Ario Pharma Ltd

Completed

A Study to Assess the Efficacy of XEN-D0501 in Reducing the Cough Frequency in Patients With Chronic Idiopathic Cough

Chronic Idiopathic Cough

United Kingdom, Ireland
Neurovalens Ltd.
University College Dublin; Exploristics Ltd; Compliance Solutions Ltd.

Completed

Effect of VeSTAL Device in Type 2 Diabetes Mellitus

Metabolic Syndrome | Type 2 Diabetes

Ireland
Neurovalens Ltd.
University College Dublin; Exploristics Ltd; Compliance Solutions Ltd.

Completed

Electrical Vestibular Nerve Stimulation (VeNS) Compared to Sham Control as a Means of Reducing Excess Body Weight

Obesity | Overweight | Metabolic Syndrome | Overweight and Obesity | Overweight or Obesity

Ireland
Nemysis Ltd
RDC Clinical Pty Ltd

Recruiting

Safety and Effectiveness of Iron Hydroxide Adipate Tartrate (IHAT) in Iron Deficient Premenopausal Women

Iron-deficiency

Australia
Nuritas Ltd
RDC Clinical Pty Ltd

Recruiting

Effects of PeptiSleep in Healthy Males and Females With Mild to Moderate Sleep Impairment

Sleep

Australia

Clinical Trials Sponsored by Medolution Ltd.

Sponsors and Collaborators

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