Clinical Trials Sponsored by Merck Serono Co., Ltd., Japan

Total 312 results

Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., Japan

Terminated

A Multicentre, Open Label, Phase 1 Trial in Japan of the Mitogen Activated Protein Extracellular Signal Regulated Kinase (MEK) Inhibitor Pimasertib Given Orally to Subjects With Solid Tumors as Monotherapy

Hepatocellular Carcinoma | Advanced Solid Tumors

Japan
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., Japan

Completed

Trial to Assess the Clinical Efficacy and Safety of MSJ-0011 in Inducing Ovulation in Anovulatory or Oligo-ovulatory Japanese Women

Polycystic Ovarian Syndrome | Anovulation | Oligo-ovulation | Hypothalamic-pituitary Dysfunction

Japan
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., Japan

Completed

Study of Tecemotide (L-BLP25) in Participants With Stage III Unresectable Non-small Cell Lung Cancer (NSCLC) Following Primary Chemoradiotherapy

Non-small Cell Lung Cancer

Germany
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., Japan

Completed

SJ-0021 (Gonalef®) Versus Purified Pituitary Gonadotropin (Fertinorm-P®) for Ovulation Induction in Japanese Infertile Women

Infertility | Ovulation Induction

Japan
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd.

Terminated

Efficacy and Safety of Crinone Versus Combination Medication (ACCESS)

Infertility

China
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Terminated

Efficacy Study of Oral Nicorandil on Improving Microvascular Function in Female Non-obstructive Coronary Artery Disease (CAD) Participants (SPET)

Non-obstructive Coronary Artery Disease

China
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Terminated

Efficacy of Oral Bisoprolol on Heart Rate Reduction in Chinese Chronic Heart Failure Participants (Biso-CHF)

Heart Failure

China
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Completed

A Randomized Controlled Study to Assess the Effects of Bisoprolol and Atenolol on Resting Heart Rate and Sympathetic Nervous System's Activity in Subjects With Essential Hypertension

Hypertension

China
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Terminated

Colposeptine for the Treatment of Bacterial Vaginosis

Vaginosis, Bacterial

China
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Completed

A Study to Explore Correlation Between Symptoms and Signs of Polycystic Ovarian Syndrome (PCOS) and Risk of Over-response to Ovarian Stimulation (ARTIST)

Polycystic Ovary Syndrome

Germany
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Completed

Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ Electromechanical Device for Growth Hormone Treatment (ECOS CHN)

Growth Disorders

China
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Completed

Comparison of Bisoprolol With Metoprolol Succinate Sustained-release on Heart Rate and Blood Pressure in Hypertensive Patients (CREATIVE)

Hypertension

China
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Completed

Predictive Markers in Chinese Growth Hormone Deficiency (GHD) Children Treated With Saizen®

Dwarfism, Pituitary
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Completed

Retrospective Study to Estimate the Current Status of Patients With Non-Obstructive coroNary Artery Disease (RESPOND)

Non-Obstructive Coronary Artery Disease

Germany
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Completed

Research on Nicorandil Treatment of Patients Diagnosed as CHD (Coronary Heart Disease) With Stable Angina (SIGMART)

Coronary Disease | Stable Angina

China
Otsuka Pharmaceutical Co., Ltd.
UCB Japan Co. Ltd.

Completed

Efficacy Confirmation Trial of CDP870 Without Coadministration of Methotrexate (MTX) in Japanese Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

Japan
Abbott
Eisai Co., Ltd.; Abbott Japan Co.,Ltd

Completed

Adalimumab in Adult Japanese Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Japan
Abbott
Eisai Co., Ltd.; Abbott Japan Co.,Ltd

Completed

Adalimumab in Adult Japanese Subjects With Psoriasis

Psoriasis

Japan
Abbott
Eisai Co., Ltd.; Abbott Japan Co.,Ltd

Completed

A Study of Adalimumab for the Induction of Clinical Remission in Japanese Subjects With Crohn's Disease

Crohn's Disease

Japan
Abbott
Eisai Co., Ltd.; Abbott Japan Co.,Ltd

Completed

Self-injection of Adalimumab in Adult Japanese Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Japan
Abbott
Eisai Co., Ltd.; Abbott Japan Co.,Ltd

Completed

Adalimumab in Adult Japanese Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Japan
Abbott
Abbott Japan Co.,Ltd

Completed

A Study of Single Doses of ABT-072 in Japanese Healthy Male Adults

Hepatitis C

Japan
Abbott
Abbott Japan Co.,Ltd

Completed

A Study of Single Dose of ABT-333 in Healthy Male Adults

HCV Infections

Japan
Citizen Systems Japan Co., Ltd.

Completed

Clinical Test Report for Blood Pressure Meter CH-609

Blood Pressure

Taiwan
Abbott
Abbott Japan Co.,Ltd

Completed

Dose-response Study of Paricalcitol Injection in Chronic Kidney Disease Patients Receiving Hemodialysis

Secondary Hyperparathyroidism | Chronic Kidney Disease on Hemodialysis

Japan
Citizen Systems Japan Co., Ltd.

Completed

Clinical Test for Blood Pressure Meter of CH-101

Blood Pressure

Taiwan
Otsuka Pharmaceutical Co., Ltd.
UCB Japan Co. Ltd.

Completed

Efficacy Confirmation Trial of CDP870 as add-on Medication to Methotrexate (MTX) in Japanese Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

Japan
Neopharma Japan Co., Ltd.
Parexel

Withdrawn

A Study to Assess the Safety and Efficacy of 5-aminolevulinic Acid Hydrochloride (5-ALA HCl) and Sodium Ferrous Citrate (SFC) Added on Artemisinin-based Combination Therapy (ACT) in Adult Patients With Uncomplicated Malaria

Malaria
Abbott
Abbott Japan Co.,Ltd

Completed

Long-term Safety Study of Paricalcitol Injection in Chronic Kidney Disease Patients With Hemodialysis (HD)

Hemodialysis | Secondary Hyperparathyroidism

Japan
Citizen Systems Japan Co., Ltd.

Completed

Clinical Test Report for Blood Pressure Meter of CH-658

Blood Pressure

Japan
LEO Pharma
CMIC Co, Ltd. Japan

Completed

LEO 80185 Gel (Calcipotriol Hydrate Plus Betamethasone Dipropionate) in Japanese Subjects With Psoriasis

Psoriasis Vulgaris

Japan
UCB Japan Co. Ltd.

Completed

An Open Label Study of Levetiracetam in Japanese Pediatric Patients With Partial Seizures

Epilepsy | Partial Seizures

Japan
UCB Japan Co. Ltd.

Completed

Multiple-dose Study of Levetiracetam Injection in Japanese and Caucasian Healthy Males

Healthy Volunteers

Japan
UCB Japan Co. Ltd.

Completed

A Study of Levetiracetam as Monotherapy or Adjunctive Treatment of Partial Seizures in Pediatric Epileptic Subjects Ranging From 1 Month to Less Than 4 Years of Age (PEACH)

Partial Seizures

Japan
UCB Japan Co. Ltd.

Completed

A Trial to Evaluate the Long Term Safety and Tolerability of Lacosamide Taken as Monotherapy in Adults With Partial-onset Seizures

Epilepsy | Partial-onset Seizures

Japan
Alexion Pharmaceuticals
CMIC Co, Ltd. Japan

Completed

E07-001: Safety and Efficacy Extension Study of Eculizumab in Paroxysmal Nocturnal Hemoglobinuria Patients

Paroxysmal Nocturnal Hemoglobinuria
UCB Japan Co. Ltd.

Completed

Follow-up Study of L059 (Levetiracetam) in Epileptic Patients With Partial Onset Seizures by Open Label Method

Epilepsy, Partial
UCB Japan Co. Ltd.

Completed

A Double-blind, Placebo-controlled Study of Levetiracetam in Epilepsy Patients With Generalized Tonic-clonic Seizures (Except Partial Seizures Evolving to Secondarily Generalized Seizures)

Epilepsy | Generalized Tonic-Clonic Seizures

China, Japan
UCB Japan Co. Ltd.

Completed

An Open Label Study of Levetiracetam Monotherapy in Patients With Newly Diagnosed Focal Epilepsy

Epilepsy | Partial Onset Seizures

Japan
UCB Japan Co. Ltd.

Completed

A Study of Levetiracetam in Japanese Pediatric Patients With Generalized Tonic-clonic Seizures

Epilepsy | Generalized Tonic-clonic Seizures

Japan
UCB Japan Co. Ltd.

Completed

Maintenance Study of Certolizumab Pegol (CZP) in Crohn's Disease

Crohn's Disease

Japan
UCB Pharma
UCB Japan Co. Ltd.

Completed

Bridging Study of L059 (Levetiracetam) in Patients With Epilepsy by Double Blind Method

Epilepsy
UCB Japan Co. Ltd.

Completed

An Open Label Study of L059 Intravenous (IV) in Japanese Epilepsy Subjects With Partial Onset Seizures

Epilepsy | Partial Onset Seizures

Japan
Otsuka Medical Devices Co., Ltd. Japan

Recruiting

A Clinical Study of the Paradise™ Renal Denervation System in Patients With Hypertension (RADIANCE-HTN DUO)

Cardiovascular Diseases | Vascular Diseases | Hypertension

Japan
Otsuka Medical Devices Co., Ltd. Japan

Active, not recruiting

Clinical Study of an Ultrasound Renal Denervation System in Patients With Heart Failure

Chronic Heart Failure

Japan
Otsuka Medical Devices Co., Ltd. Japan

Active, not recruiting

Evaluate the Efficacy and Safety of the Cilostazol-coated BioMimics 3D Stent System in Patients With Peripheral Arterial Occlusive Disease

Peripheral Arterial Disease

Japan
UCB Japan Co. Ltd.

Completed

A Long Term Follow up Administration Study of L059 (Levetiracetam) in Epilepsy Patients With Partial Onset Seizures

Epilepsies | Partial

Japan
Medtronic Vascular
Medtronic Japan Co., Ltd.

Completed

RESOLUTE Japan - The Clinical Evaluation of the MDT-4107 Drug-Eluting Coronary Stent (RJ)

Myocardial Ischemia | Cardiovascular Diseases | Coronary Artery Disease | Arterial Occlusive Diseases

Japan
UCB Japan Co. Ltd.

Completed

A Double-blind Confirmatory Trial of Levetiracetam in Epilepsy Patients With Partial Onset Seizures

Epilepsies, Partial

Japan
UCB Japan Co. Ltd.

Completed

Efficacy and Safety of Olokizumab With Rheumatoid Arthritis With Previously Failed to Anti-tumor Necrosis Factor (Anti-TNF) Therapy

Rheumatoid Arthritis

Japan, Korea, Republic of, Taiwan

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