Clinical Trials Sponsored by Merck, S.A., Portugal

Total 80 results

Merck KGaA, Darmstadt, Germany
Merck B.V., Netherlands; Merck A.E., Greece; Merck OY, Finland; Merck A.B., Sweden and other collaborators

Completed

Safety, Tolerability and Adherence With Rebif® New Formulation in Real Life Settings (STAR) (STAR)

Multiple Sclerosis, Relapsing Remitting

Greece
Clínica de Gastroenterologia
Nestlé Portugal SA; Angelini Pharma Portugal, Unipessoal, Lda

Completed

Comparative Study Between Colonoscopy Bowel Preparation With Clear Liquids, With and Without Two Servings of High Energy Nutritional Supplement

Colonoscopy | Bowel Preparation

Portugal
Merck KGaA, Darmstadt, Germany
Merck S.A. Columbia

Completed

To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in Columbia (ECOS COL)

Growth Disorders

Colombia
Merck KGaA, Darmstadt, Germany
Merck Serono S.A., Geneva

Completed

Drug-Drug Interaction of Cladribine and Pantoprazole in Multiple Sclerosis Subjects

Multiple Sclerosis
Merck KGaA, Darmstadt, Germany
Merck N.V.-S.A., Belgium

Terminated

An Observational Study to Compare the Dose of Gonal-fTM FbM Prescribed by the Doctor With the Recommendation of the Dose Calculator Consort and to Evaluate the Ease of Use of Pre-filled Pen of Gonal-fTM FbM Pen

Multifollicular Stimulation

Belgium
Merck KGaA, Darmstadt, Germany
Merck Serono S.A., Geneva

Completed

First Year Growth Response Associated Genetic Markers Validation Phase IV Open-label Study in Growth Hormone Deficient and Turner Syndrome Pre-pubertal Children: the PREDICT Pharmacogenetics Validation Study

Turner Syndrome | Idiopathic Growth Hormone Deficiency

Spain, France, Canada, United Kingdom, Czech Republic, Argentina, Germany, Italy, Sweden
Merck KGaA, Darmstadt, Germany
Merck Serono S.A., Geneva

Completed

An Observational Study for the Assessment of Adherence, Effectiveness and Convenience of Rebif® Treatment in Relapsing Multiple Sclerosis Patients Using RebiSmart™. (SMART)

Multiple Sclerosis, Relapsing-Remitting

Netherlands
Merck KGaA, Darmstadt, Germany
Merck Serono S.A., Geneva

Completed

Study of AS902330 (rhFGF-18) Administered Intra-articularly in Patients With Knee Primary Osteoarthritis Who Are Candidates for Total Knee Replacement

Knee Osteoarthritis

Denmark, Finland, Sweden, United Kingdom, Bulgaria, South Africa
Merck KGaA, Darmstadt, Germany
Merck Serono S.A., Geneva

Completed

Saizen in Intra-uterine Growth Retardation

Children Born With Serious Intra-uterine Growth Retardation
Merck KGaA, Darmstadt, Germany
Merck Serono S.A., Geneva

Completed

Trial of MSC1936369B in Subjects With Solid Tumors

Cancer | Solid Tumors

France, Belgium, Australia, Netherlands
Merck KGaA, Darmstadt, Germany
Merck S.A. de C.V., Mexico

Completed

To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in Mexico (ECOS MEX)

Growth Disorders

Mexico
Merck KGaA, Darmstadt, Germany
Merck S.A. de C.V., Mexico

Completed

Neuropathic Pain Management (M-F0434)

Diabetic Neuropathies | Polyneuropathies

Mexico
Merck KGaA, Darmstadt, Germany
Merck S.A. de C.V., Mexico

Completed

Efficacy and Safety of Gabapentin/B-complex Versus Pregabalin in Diabetic Peripheral Neuropathy Pain Management

Diabetic Peripheral Neuropathic Pain

Mexico
Merck KGaA, Darmstadt, Germany
Merck, S.L., Spain

Completed

Cetuximab in Refractory Colorectal Cancer With K-RAS Mutated and Favorable FcγRIIa (CD32) Genotype (MUTEX)

Colorectal Neoplasms

Spain
Merck KGaA, Darmstadt, Germany
Merck, S.L., Spain

Terminated

A Phase II Study to Assess the Efficacy and Safety of Luveris® (Lutropin Alfa) in Mid Follicular Phase for Controlled Ovarian Stimulation (COS) in Advanced Reproductive Age

Infertility | Ovulation Induction

Spain
Merck KGaA, Darmstadt, Germany
Merck, S.L., Spain

Terminated

A Clinical Trial to Determine the Effect of Lutropin Alfa on Embryo Quality and Implantation Rate in Advanced Reproductive Age

Infertility | Ovulation Induction

Spain
Merck KGaA, Darmstadt, Germany
Merck, S.L., Spain

Completed

Growth Hormone in Neuroendocrine Dysfunction With Severe Fibromyalgia Syndrome

Fibromyalgia

Spain
Merck KGaA, Darmstadt, Germany
Merck, S.L., Spain

Completed

Follow-up to Adult Height of a Cohort of Subjects Born Small for the Gestational Age and Treated With Growth Hormone (SGA)

Infant, Small for Gestational Age

Spain
Merck KGaA, Darmstadt, Germany
Merck, S.L., Spain

Completed

To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in Spain (ECOS ESP)

Growth Disorders

Spain
Merck KGaA, Darmstadt, Germany
Merck, S.L., Spain

Withdrawn

Evaluate Adherence to Treatment With Glucophage Sachets Versus Tablets in Diabetes Type 2 Patients Previously Treated With Metformin Tablets

Diabetes Mellitus Type 2
Spanish Cooperative Group for the Treatment of...
Merck, S.L., Spain; Pierre Fabre Ibérica, S.A.

Not yet recruiting

Study to Evaluate the Efficacy and Safety of Cetuximab in Combination With Encorafenib Plus Binimetinib as Induction Treatment in BRAF V600E Mutated MSS Initially Resectable or Potentially Resectable Advanced Colorectal Cancer (CEBBRA)

Colorectal Cancer
Faes Farma, S.A.
Merck Sharp & Dohme LLC; Allied Research International

Completed

Efficacy, Safety and PK of Once or Twice Daily Bilastine (10 or 20 mg) Compared With Placebo in the Symptomatic Treatment of SAR

Hypersensitivity | Allergic Conjunctivitis | Seasonal Allergic Rhinitis | Hay Fever

United States
Isala
Merck Serono International SA

Unknown

Predicting Ovarian Response in Artificial Insemination With Low Stimulation

Subfertility

Netherlands
Merck KGaA, Darmstadt, Germany
Merck Serono GmbH, Germany; Merck B.V., Netherlands; Merck A.E., Greece; Merck... and other collaborators

Completed

PERgoveriS In Stratified Treatment for Assisted Reproductive Technique (PERSIST)

Assisted Reproductive Techniques | Reproductive Technology, Assisted

Italy, Russian Federation, United Kingdom, Germany, Poland, Finland, Slovakia, Netherlands, Denmark, France, Greece
Associació per a la Recerca Oncologica, Spain
Pivotal S.L.; Merck, S.L., Spain

Completed

Avelumab Plus Carboplatin-gemcitabine in Urothelial Carcinoma (INDUCOMAIN)

Metastatic Urothelial Cancer

Spain
EMD Serono
Merck Serono International SA

Completed

Tolerability of Rebif® Injection With and Without the Use of Rebiject™Mini in Relapsing-Remitting Multiple Sclerosis Subjects

Multiple Sclerosis, Relapsing-remitting
EMD Serono
Merck Serono International SA

Completed

A Study of Rebif® Compared With Avonex® in the Treatment of Relapsing-remitting Multiple Sclerosis (MS)

Multiple Sclerosis, Relapsing-Remitting
Ambrx, Inc.
Merck Serono International SA

Completed

Safety, Tolerability and PK/PD Study in Young Adult Patients With Childhood Onset Growth Hormone Deficiency (GHD).

Growth Hormone Deficiency

Hungary
Maimónides Biomedical Research Institute of Córdoba
MERCK SHARP & DOHME DE ESPAÑA S.A.

Not yet recruiting

Efficacy of Letermovir in Preventing Cytomegalovirus (CMV) Infection in Lung Transplant Recipients vs. Valganciclovir. (LETERCOR)

Infections, Cytomegalovirus

Spain
Trial Form Support S.L.
Merck KGaA, Darmstadt, Germany

Unknown

Cetuximab & Concomitant-Boost Accelerated RT in Patients With Locally Advanced Oropharynx Squamous Cell Carcinoma.

Oropharyngeal Neoplasms

Spain
Laval University
Merck Serono International SA

Unknown

Control Ovarian Stimulation Timing Test (COST2)

Infertility

Canada
EMD Serono
Merck Serono International SA

Completed

Safety and Efficacy of Interferon-Beta-1a (Rebif®) for Treating Subjects With Acute Symptoms of Ulcerative Colitis

Ulcerative Colitis

Sweden, Germany, Netherlands, Israel, Singapore, Switzerland, United Kingdom
Pontificia Universidade Católica do Rio Grande...
Merck S.A., Brazil, an affiliate of Merck KGaA, Darmstadt, Germany

Active, not recruiting

Effects of Oral Cladribine on Remyelination and Inflammation in Multiple Sclerosis Patients (CLAREMI)

Multiple Sclerosis, Relapsing-Remitting

Brazil
Istituti Clinici Scientifici Maugeri SpA
Merck Sharp & Dohme LLC

Recruiting

Pembrolizumab in High-risk Thyroid Cancer (NePenThe)

Differentiated Thyroid Cancer

Italy
Hadassah Medical Organization
Merck Serono International SA

Terminated

Cetuximab Therapy for Third Line Rechallenge in Metastatic Colorectal Cancer

Cancer of Colon

Israel
Universitair Ziekenhuis Brussel
Merck Serono International SA

Completed

Endometrial Advancement After Rec or u-HCG Triggering

Infertility

Belgium
Nordica Fertility Clinic
Merck Serono International SA

Unknown

A Prospective Randomized Multicentre Study to Compare Crinone 8% Once Daily Versus Other Vaginal Progesterone.

IVF - Luteal Phase Support After Embryo Transfer

Denmark, Sweden
Grupo Espanol Multidisciplinario del Cancer Digestivo
Merk Sharp & Dohme España S.A.

Recruiting

Pembrolizumab and Olaparib in Homologous-recombination Deficient (HRD) Advanced Colorectal Cancer (CRC). (PEMBROLA)

Metastatic Colorectal Cancer

Spain
University of Malaya
Merck Serono International SA

Terminated

Induction and Concurrent Chemoradiotherapy With Cetuximab for Patients With Locally Advanced Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

Malaysia
Universitair Ziekenhuis Brussel
Merck Serono International SA

Unknown

Luteal Supplementation With Rec-LH After GnRH-agonist Triggering in In Vitro (IVF)

Pregnancy | Pregnancy Loss

Belgium
Universitair Ziekenhuis Brussel
Merck Serono International SA

Unknown

Pregnancy Rates in IVF After Ovulation Triggering With Recombinant or Urinary Human Chorionic Gonadotrophin (HCG)

Pregnancy | Embryonic Development | VEGF

Belgium
French Cardiology Society
Merck Serono International SA

Completed

Assessment of Endothelial Vasomotricity After Treatment by Nicotinic Acid in Acute Coronary Syndrome (EVANACS)

Acute Coronary Syndrome (ACS)

France
Istituti Clinici Scientifici Maugeri SpA
Merck Sharp & Dohme LLC

Not yet recruiting

Pembrolizumab in Locally Advanced Sinonasal Carcinoma (NeoPeSino)

Sinonasal Undifferentiated Carcinoma

Italy
Celyad Oncology SA
Merck Sharp & Dohme LLC

Recruiting

Study of Pembrolizumab Treatment After CYAD-101 With FOLFOX Preconditioning in Metastatic Colorectal Cancer

Unresectable Metastatic Colorectal Cancer

Belgium, United States
Istituto Clinico Humanitas
Merck Serono International SA

Completed

Retrospective Trial on Low Prognosis Infertile Patients

Infertility, Female | Fertility Disorders
Instituto Valenciano de Infertilidad, IVI Alicante
Fundación IVI; Syntax for Science, S.L; Merck, S.L., Spain

Recruiting

Recombinant LH Prior to Ovarian Stimulation in Poor Ovarian Responders (PRE-LH) (PRE-LH)

Infertility, Female

Spain
ART Fertility Clinics LLC
Merck Serono International SA

Completed

Step Down FSH Approach and Late Follicular Phase in Progesterone Level (FSH)

Progesterone Resistance

United Arab Emirates
Fundación Santiago Dexeus Font
Merck, S.L., Spain

Recruiting

PErsonalized Addition of Recombinant LH in Ovarian Stimulation (PEARL)

Infertility

Spain
University Hospital, Basel, Switzerland
Merck Serono International SA

Completed

Comparing Ovarian Stimulation for Assisted Reproduction With Two Different Forms of Pituitary Suppression (Pergoveris)

Complications Associated With Artificial Fertilization | Female Infertility Due to Nonimplantation of Ovum

Switzerland
Centre Hospitalier Universitaire, Amiens
Merck Serono International SA

Completed

May Metformin be Used in Renal Failure?

Renal Disorder Associated With Type II Diabetes Mellitus

France

Clinical Trials Sponsored by Merck, S.A., Portugal

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