Clinical Trials Sponsored by Murdoch Childrens Research Institute

Total 1067 results

Murdoch Childrens Research Institute

Recruiting

Beat to Beat A Study in Paediatric, Adolescent and Young Adult Patients Who Are Undergoing or Have Undergone Cancer Therapy to Evaluate the Agreement Between QTc Measured Using 12 Lead Electrocardiogram (ECG) and a Wearable Device ECG

Neoplasms | Cardiac Arrhythmia

Australia
Murdoch Childrens Research Institute

Recruiting

Pilot Study of MC in Paediatric Palliative Care

Palliative Care

Australia
Murdoch Childrens Research Institute

Recruiting

Methylphenidate in Childhood Apraxia of Speech

Childhood Apraxia of Speech

Australia
Murdoch Childrens Research Institute

Completed

Nitric Oxide During Bypass for Arterial Switch Operation (NASO)

Transposition of Great Vessels | Low Cardiac Output Syndrome

Malaysia, Australia, Canada, Indonesia
Murdoch Childrens Research Institute

Active, not recruiting

Micronised Resveratrol as a Treatment for Friedreich Ataxia

Friedreich Ataxia

Australia
Murdoch Childrens Research Institute

Completed

Investigating COVID-19 Vaccine Immunity in Children in the Melbourne Infant Study of BCG for Allergy and Infection Reduction (COSI BAIR)

COVID-19 | Vaccine Reaction | Immunization; Infection

Australia
Murdoch Childrens Research Institute

Completed

Effect of Creatine Monohydrate on Functional Muscle Strength in Children With FSHD

Facio-Scapulo-Humeral Dystrophy | FSHD2 | FSHD1

Australia
Murdoch Childrens Research Institute

Completed

Safety of Autologous Cord Blood Cells in HLHS Patients During Norwood Heart Surgery

Heart Defects, Congenital | Hypoplastic Left Heart Syndrome | Pediatric Disorder

Australia
Murdoch Childrens Research Institute
Royal Children's Hospital

Completed

What is the Incidence of an Immune Disorder in Children With Invasive Pneumococcal Disease (IPD)?

Primary Immunodeficiency | Invasive Pneumococcal Disease, Protection Against | Invasive Pneumococcal Disease, Recurrent Isolated, 1 | Invasive Pneumococcal Disease, Recurrent Isolated, 2

Australia, New Zealand
Murdoch Childrens Research Institute

Recruiting

The Egg Up Trial - Testing a New Treatment Pathway for Infants With Newly Diagnosed Egg Allergy

Food Allergy | Food Allergy in Infants

Australia
Murdoch Childrens Research Institute

Recruiting

Nausea and Vomiting in Postoperative Paediatric Patients With Patient-Controlled Analgesia (PCA): Morphine vs Oxycodone (POPCORN)

Patient-Controlled Analgesia

Australia
Murdoch Childrens Research Institute

Recruiting

Minimising Adverse Drug Reactions and Verifying Economic Legitimacy in Children (MARVEL-PIC) (MARVEL-PIC)

Neoplasms | Bone Marrow Transplantation

Australia
Murdoch Childrens Research Institute

Recruiting

Low Dose Multi-Nut Oral Immunotherapy in Pre-schoolers With a Multi-Nut Allergy (LMNOP)

Allergy, Nut

Australia
Murdoch Childrens Research Institute

Recruiting

BonE and Joint Infections - Simplifying Treatment in Children Trial (BEST)

Osteomyelitis | Septic Arthritis | Bone Infection | Bone and Joint Infection

New Zealand, Australia
Murdoch Childrens Research Institute

Completed

Is Medicinal Cannabis an Effective Treatment for Tourette Syndrome in Adolescents? A Pilot Study

Tourette Syndrome in Adolescence

Australia
Murdoch Childrens Research Institute

Completed

A Mobile Phone Self-Monitoring Tool to Increase Emotional Self-Awareness and Reduce Depression in Young People (mobiletype)

Depression

Australia
Murdoch Childrens Research Institute

Completed

A Phase II Dose-ranging Study of Oral RV3-BB Rotavirus Vaccine

Rotavirus Infections

Malawi
Murdoch Childrens Research Institute

Completed

Comparing the Intravenous Treatment of Skin Infections in Children, Home Versus Hospital (CHOICE)

Cellulitis

Australia
Murdoch Childrens Research Institute

Not yet recruiting

Analysing HIgh Dose Probiotic Peanut Oral Immunotherapy (PPOIT) and High Dose Peanut Oral Immunotherapy (OIT) Versus LOw Dose Peanut OIT for Peanut Allergy (HILO)

Peanut Allergy

Australia
Murdoch Childrens Research Institute

Recruiting

Early Versus Late Stopping of Antibiotics in Children With Cancer and High-risk Febrile Neutropenia (ELSA-FN)

Febrile Neutropenia

Australia
Murdoch Childrens Research Institute

Suspended

Can Vitamin D Treatment Help Treat Moderate to Severe Atopic Dermatitis in Young Children? The D-Vex Pilot Study (D-Vex)

Atopic Dermatitis

Australia
Murdoch Childrens Research Institute

Active, not recruiting

The TreEat Study- Can Early Introduction of Tree Nuts Prevent Tree Nut Allergy in Infants With Peanut Allergy (TreEat)

Food Allergy in Infants | Nut Allergy

Australia
Murdoch Childrens Research Institute

Active, not recruiting

Can Vitamin D Supplementation in the First Year of Life Prevent Food Allergy in Infants? The VITALITY Trial: Parts 1&2 (VITALITY)

Food Allergy

Australia
Murdoch Childrens Research Institute

Completed

Clinical Hypnosis and Home Blood Pressure Monitoring in Children With Neurofibromatosis Type 1

Hypertension | Blood Pressure | Neurofibromatosis 1

Australia
Murdoch Childrens Research Institute
Royal Children's Hospital

Recruiting

Single Dose Intravenous Antibiotics for Complicated Urinary Tract Infections in Children (CHOICE UTI)

Infection | Pediatric Infectious Disease | Complicated Urinary Tract Infection

Australia, New Zealand
Murdoch Childrens Research Institute
Royal Children's Hospital; Monash Health

Recruiting

Intranasal Steroid as Medical Therapy For Sleep-Disordered Breathing in Children (MIST+)

Snoring | Tonsillar Hypertrophy | Sleep Disorder; Breathing-Related | Obstructive Sleep Apnea of Child | Sleep Disorders in Children | Adenoidal Disorder

Australia
Murdoch Childrens Research Institute
Monash University

Completed

Does Treatment With Montelukast Improve Symptoms of Atopic Dermatitis in Children?

Dermatitis, Atopic

Australia
Murdoch Childrens Research Institute
Monash Medical Centre

Terminated

HPV Vaccination in Special Risk Groups: 5 Year Follow-up

PRD (Paediatric Rheumatological Disease) | IBD (Inflammatory Bowel Disease)

Australia
Murdoch Childrens Research Institute
Rhinomed Pty Ltd

Completed

Diagnosis of Respiratory Viruses in Children With Rhinoswab Junior

COVID-19 | SARS CoV 2 Infection

Australia
Bandim Health Project
Murdoch Childrens Research Institute

Completed

Does Timeliness of DTaP-IPV-Hib Vaccination Affect Development of Atopic Dermatitis Before 1 Year of Age?

Atopic Dermatitis
Bandim Health Project
Murdoch Childrens Research Institute

Completed

Bacille Calmette-Guérin (BCG) Vaccine and Atopy

Food Hypersensitivity | Asthma | Eczema

Guinea-Bissau
Murdoch Childrens Research Institute
Friedreich's Ataxia Research Alliance

Completed

A Study of Resveratrol as Treatment for Friedreich Ataxia

Friedreich Ataxia

Australia
Murdoch Childrens Research Institute
La Trobe University

Completed

CanMove: A Physical Activity Program for Children With Cancer

Pediatric Cancer

Australia
Murdoch Childrens Research Institute
University of Melbourne

Completed

Neurobehavioural Development of Infants Born <30 Weeks Gestational Age Between Birth and Five Years of Age (VIBeS-2)

Neurodevelopmental Disorders | Motor Activity | Developmental Coordination Disorder | Preterm Infant

Australia
Murdoch Childrens Research Institute
Royal Children's Hospital; Royal Hospital For Women

Completed

RCT of Continuous Versus Intermittent Infusion of Vancomycin in Neonates

Sepsis | Bacteremia | Infection

Australia
Murdoch Childrens Research Institute
Australian Wool Innovation Limited

Completed

Wool Clothing for the Management of Childhood Atopic Dermatitis

Dermatitis, Atopic
Murdoch Childrens Research Institute
Ministry of Health, Fiji

Completed

Preventing Young Infant Infections Using Azithromycin in Labour (PreYIAL) Trial (PreYIAL)

Bacterial Infections

Fiji
Murdoch Childrens Research Institute
Bill and Melinda Gates Foundation; Royal Children's Hospital

Completed

BCG Vaccination to Protect Healthcare Workers Against COVID-19 (BRACE)

COVID-19 | Corona Virus Infection | Coronavirus Disease 2019 (COVID-19) | Respiratory Illness

Australia, Brazil, Netherlands, Spain, United Kingdom
Murdoch Childrens Research Institute
Royal Children's Hospital; Mercy Hospital for Women, Australia

Completed

A Trial Investigating the Influence of BCG and Hepatitis B Immunisation at Birth on Neonatal Immune Responses: The Early Life Vaccines and Immunity Study (ELVIS)

Innate Immune Response

Australia
Murdoch Childrens Research Institute
Royal Children's Hospital; Peter MacCallum Cancer Centre, Australia

Not yet recruiting

A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations (TARGET-VM)

Arteriovenous Malformations | Vascular Malformations | MAP2K1 Gene Mutation | PIK3CA-related Overgrowth Spectrum | Vascular Anomalies | Lymphangioma | Lymphatic Malformation | KRAS G12D | Venous Malformation | Vascular Anomaly | KRAS G12C | PI3K Gene Mutation | Slow-Flow Vascular Malformation | Fast-Flow Vascular... and other conditions

Australia
Murdoch Childrens Research Institute
Pasteur Institute, Ho Chi Minh City

Completed

Trial of Simplified Pneumococcal Vaccination in Vietnam II (VPTII)

Pneumococcal Vaccine

Vietnam
Boston Children's Hospital
Food and Drug Administration (FDA); Royal Children's Hospital; Murdoch Childrens... and other collaborators

Completed

A Multi-site Randomized Controlled Trial Comparing Regional and General Anesthesia for Effects on Neurodevelopmental Outcome and Apnea in Infants (GAS)

Inguinal Hernia

United States, Canada, Australia, Italy, United Kingdom, Netherlands, New Zealand
Murdoch Childrens Research Institute
Brockhoff Foundation Australia; Shepherd Foundation Australia

Completed

Protecting Young Special Risk Females From Cervical Cancer Through Human Papilloma Virus (HPV) Vaccination (HPV)

Cervical Cancer

Australia
Great Ormond Street Hospital for Children NHS Foundation...
The Hospital for Sick Children; Boston Children's Hospital; Murdoch Childrens...

Recruiting

Gene-STEPS: Shortening Time of Evaluation in Paediatric Epilepsy Services (Gene-STEPS)

Epilepsy

United States, Canada, Australia, United Kingdom
Murdoch Childrens Research Institute
Burnet Institute; Lao Tropical and Public Health Institute

Active, not recruiting

Ivermectin Therapy for Scabies Infection in Children Younger Than 5 Years of Age (ITCHY Study) (ITCHY)

Scabies | Scabies; Itch

Lao People's Democratic Republic
Murdoch Childrens Research Institute
Sydney Children's Hospitals Network; Royal Children's Hospital; Monash Health; Royal...

Not yet recruiting

Improving Therapeutic Drug Monitoring and Dosing for Vancomycin in Young Infants With Infections (VANCAPP) (Part 2) (VANCAPP)

Infections | Sepsis | Bacteremia

Australia
Murdoch Childrens Research Institute
Lao-Oxford-Mahosot Hospital Wellcome Trust Research Unit

Recruiting

Laos Out-Of-Pocket Costs: an Observational Study on the Impact of Severe Childhood Illness on the Health, Wealth and Wellbeing of Household Members in Laos (LOOP)

Child Health | Health Care Economics | Cost of Illness | Burden of Illness

Lao People's Democratic Republic
Murdoch Childrens Research Institute
Royal Children's Hospital; RCH League of Former Trainees and Associates Inc

Completed

Vaccination Coverage and Uptake in Young People Experiencing or at Risk of Homelessness

Homeless Youth

Australia
Murdoch Childrens Research Institute
Royal Children's Hospital; University of Melbourne; Mercy Hospital for Women,...

Active, not recruiting

Melbourne Infant Study - Bacille Calmette Guérin (BCG) for Allergy & Infection Reduction (MIS BAIR)

Respiratory Tract Infections | Allergy | Eczema

Australia
Children's Hospital Medical Center, Cincinnati
Uganda Heart Institute; Murdoch Children's Research Institute, Melbourne Australia

Active, not recruiting

A Long-term Follow up Study for Patients Who Participated in the GOAL Trial (GOAL-Post)

Rheumatic Heart Disease

Uganda

Clinical Trials Sponsored by Murdoch Childrens Research Institute

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