Clinical Trials Sponsored by New England Research Institutes

Total 564 results

Community Research Initiative of New England

Completed

Efficacy Study of Substitution of Darunavir/Ritonavir (DRV/r) for Dual-boosted Protease Inhibitors (DVD)

HIV Infections

United States
Community Research Initiative of New England

Completed

BRAVO: Background Regimen of Raltegravir on Virologic Outcome (BRAVO)

HIV Infections

United States
Community Research Initiative of New England
Abbott

Terminated

BOOST: Study of Increased Dosage of Lopinavir/Ritonavir (LPV/r)

HIV Infections

United States
Community Research Initiative of New England
Gilead Sciences

Completed

A Pilot Study of Treating HCV at a Psychiatrist-staffed Outpatient Addiction Clinic

Hepatitis C | Hepatitis C, Chronic | Opiate Dependence

United States
Community Research Initiative of New England
Tibotec Pharmaceutical Limited

Completed

Lopinavir/r or Fosamprenavir/r Switch to Atazanavir/r or Darunavir/r (LARD)

HIV Infections

United States
Community Research Initiative of New England
The Campbell Foundation

Completed

FOTO: Five Consecutive Days on Treatment With Efavirenz, Tenofovir, and Emtricitabine Followed by Two Days Off Treatment Versus Continuous Treatment

HIV Infections

United States
Northeastern University
National Eye Institute (NEI); New England College of Optometry; Lighthouse Guild

Recruiting

Eye Movement Rehabilitation in Low Vision Patients

Age Related Macular Degeneration | Low Vision

United States
Community Research Initiative of New England
Merck Sharp & Dohme LLC

Withdrawn

A Pilot Study to Determine if Raltegravir Eradicates HIV From Peripheral Blood Mononuclear Cells

HIV Infections | Acquired Immune Deficiency Syndrome
Community Research Initiative of New England

Completed

An Evaluation of Pentoxifylline in HIV-Positive Persons With Symptomatic HIV Infection and a Karnofsky Score > 40 Percent and < 100 Percent

HIV Infections

United States
Community Research Initiative of New England

Completed

A Study to Evaluate the Effect of Cimetidine on CD4 Lymphocyte Counts in HIV Infection

HIV Infections

United States
Community Research Initiative of New England
Bristol-Myers Squibb; Merck Sharp & Dohme LLC

Completed

BATAR: Individuals Currently Taking Boosted Atazanavir as Part of an HIV Treatment Regimen Will be Evaluated to See if Substituting Raltegravir for Nucleoside Transcriptase Inhibitors Will be Safe and Well Tolerated. (BATAR)

HIV

United States
Institute of Cancer Research, United Kingdom
Public Health England

Active, not recruiting

Transcriptional Responses as an Indicator of Individualised Responses to Radiation Effects (RTGene 2)

Cancer

United Kingdom
Institute of Cancer Research, United Kingdom
Public Health England

Completed

Feasibility Study Testing Transcriptional Responses as an Indicator of Individualised Responses to Radiation Effects (RTGene)

Cancer

United Kingdom
University of New England
Boston University; Institute of Population, Health and Development, Vietnam

Completed

Supporting Adolescent Adherence in Vietnam (SAAV) (SAAV)

HIV/AIDS | Patient Adherence | Adolescents

Vietnam
New York Glaucoma Research Institute

Unknown

A Study to Assess the Effect of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Patients With Uncontrolled Advanced Glaucoma With Prior Failed Trabeculectomy or Tube Shunt

Advanced Glaucoma

United States
New York Glaucoma Research Institute

Unknown

A Study to Assess the Effect of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Patients With Chronic Angle-closure Glaucoma (ROCK - CACG)

Chronic Angle-closure Glaucoma

United States
New York Glaucoma Research Institute

Unknown

A Compassionate Case Study to Assess the Hypotensive Efficacy of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Glaucoma Patients With Uncontrolled Intraocular Pressure to Avoid Surgical Intervention

Glaucoma

United States
Yale University
National Institutes of Health (NIH); National Institute on Aging (NIA); Trinity...

Completed

QBSAfe: A Novel Approach to Diabetes Management Focused on Quality of Life, Burden of Treatment, Social Integration and Avoidance of Future Events (QBSAfe)

Diabetes Mellitus | Diabetes

United States
University of Maine
National Institutes of Health (NIH); National Institute on Aging (NIA); University...

Completed

Balancing Act: Impact on Falls in Older Adults With Vision Impairment

Postural Balance

United States
Boston University Charles River Campus
National Institute on Aging (NIA); University of New England

Completed

Amped-PD: Amplifying Physical Activity Through Music in Parkinson Disease (Amped-PD)

Parkinson Disease

United States
New England College of Optometry
University of California, Los Angeles; National Institute on Disability, Independent...

Completed

Community Access Through Remote Eyesight (CARE) Study (CARE)

Low Vision

United States
David J. Gagnon
National Institute of General Medical Sciences (NIGMS); University of New England and other collaborators

Recruiting

Ceftriaxone to PRevent pneumOnia and inflammatTion aftEr Cardiac arresT (PROTECT) (PROTECT)

Pneumonia | Out-Of-Hospital Cardiac Arrest

United States
West Virginia School of Osteopathic Medicine
University of New England; American Academy of Osteopathy; Osteopathic Research...

Completed

Osteopathic Otitis Media Research Study (OOMRS)

Otitis Media With Effusion

United States
Heart of England NHS Trust
National Institute for Health Research, United Kingdom

Unknown

Evaluation of the Effect of Cooled Haemodialysis on Cognitive Function in Patients Suffering With End-stage KD (E-CHECKED)

Cognitive Impairment

United Kingdom
University of New Mexico
Heffter Research Institute

Completed

Effects and Therapeutic Potential of Psilocybin in Alcohol Dependence

Alcohol Dependence

United States
New York Stem Cell Foundation Research Institute

Recruiting

NYSCF Scientific Discovery Biobank

PTSD | Multiple Sclerosis | Cervical Cancer | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Diabetes | Macular Degeneration | Diabetes Mellitus, Type 1 | Parkinson Disease | Amyotrophic Lateral Sclerosis | Dementia | Ovarian Cancer | Alzheimer Disease | ALS | Vulvar Cancer | Post Traumatic Stress Disorder | Lewy Body Disease and other conditions

United States
The Miriam Hospital
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Planned Parenthood...

Completed

Women SHARE Study: Reducing Sexual Risk (HIV)

Sexually Transmitted Diseases | Alcohol and Substance-Related Mental Disorders

United States
King's College London
Public Health England; National Institute for Health Research, United Kingdom

Completed

Improving the Behavioural Impact of Air Quality Alerts

Health Behavior | Pollution; Exposure

United Kingdom
King's College London
Public Health England; National Institute for Health Research, United Kingdom

Completed

Improving Communication During a Pandemic Flu Outbreak

Healthy
New York State Psychiatric Institute
Stanley Medical Research Institute

Completed

Kuvan in People With Schizophrenia and Schizoaffective Disorder

Schizophrenia | Schizoaffective Disorder

United States
New York State Psychiatric Institute
Stanley Medical Research Institute

Completed

TDCS for Auditory Hallucinations in Schizophrenia

Schizophrenia

United States
New York State Psychiatric Institute
Stanley Medical Research Institute

Completed

Tocilizumab as Add-On Treatment For Residual Positive, Negative, and Cognitive Symptoms of Schizophrenia

Schizophrenia | Schizoaffective Disorder

United States
George Washington University
University of Pittsburgh; Medstar Health Research Institute; Quality Insights; Renal... and other collaborators

Completed

Advance Care Planning Coaching for Patients With Chronic Kidney Disease (MY WAY)

Chronic Kidney Diseases

United States
Foundation for Innovative New Diagnostics, Switzerland
Burnet Institute; Papua New Guinea Institute of Medical Research

Unknown

Clinical Performance of the Histidine Rich Protein 2 (HRP2) Highly Sensitive Rapid Diagnostic Test (HS-RDT) for Malaria Diagnosis in Pregnant Women in Papua New Guinea

Diagnoses Disease | Plasmodium Falciparum Malaria | Pregnancy Malaria
University of New Mexico
University of Miami; The City College of New York; The Mind Research Network; New... and other collaborators

Completed

High-Definition Transcranial Direct Current Stimulation (HD-tDCS) for Sensory Deficits in Complex Traumatic Brain Injury (NAVIGATE-TBI)

Mild Traumatic Brain Injury

United States
New York State Psychiatric Institute
Feinstein Institute for Medical Research

Completed

Exercise and Inflammation

Cardiovascular Disease

United States
Telethon Kids Institute
Papua New Guinea Institute of Medical Research

Completed

PCV13 in Non-pregnant Papua New Guinean Women

Pneumococcal Infections

Papua New Guinea
Ludwig Institute for Cancer Research
Cancer Research Institute, New York City; MedImmune LLC

Completed

A Study of Tremelimumab and IV Durvalumab Plus Poly-ICLC in Subjects With Biopsy-accessible Cancers

Melanoma | Sarcoma | Breast Cancer | Solid Tumor | Prostate Cancer | Bladder Cancer | Head and Neck Squamous Cell Carcinoma | Cutaneous T-Cell Lymphoma | Renal Cancer | Merkel Cell Carcinoma | Testicular Cancer

United States
Volcano Corporation
Duke Clinical Research Institute; Cardiovascular Research Foundation, New York

Completed

Physiologic Assessment of Coronary Stenosis Following PCI (DEFINE PCI)

Coronary Artery Disease | Angina, Stable | Angina, Unstable | Coronary Stenosis

United States, Netherlands, United Kingdom
Ludwig Institute for Cancer Research
Cancer Research Institute, New York City; MedImmune LLC

Completed

A Phase 1 Study to Evaluate MEDI4736 in Combination With Tremelimumab

Renal Cell Carcinoma | Cervical Cancer | Breast Cancer | Colorectal Cancer | Ovarian Cancer

United States
HeartFlow, Inc.
Duke Clinical Research Institute; Cardiovascular Research Foundation, New York

Completed

The PRECISE Protocol: Prospective Randomized Trial of the Optimal Evaluation of Cardiac Symptoms and Revascularization (PRECISE)

Coronary Artery Disease

United States
New York Stem Cell Foundation Research Institute
Silverstein Foundation

Recruiting

Drug Discovery for Parkinson's With Mutations in the GBA Gene

Healthy | Parkinson Disease | Gaucher Disease | GBA Gene Mutation

United States
Leap Therapeutics, Inc.
Cancer Research Institute, New York City

Completed

Trial of TRX518 (Anti-GITR mAb) in Stage III or IV Malignant Melanoma or Other Solid Tumors (TRX518-001)

Unresectable Stage III or Stage IV Malignant Melanoma or Other Solid Tumor Malignancies

United States
University of New Mexico
Patient-Centered Outcomes Research Institute

Completed

Effectiveness of Peer-Delivered Trauma-Specific Treatment

Substance Use Disorders | Post-Traumatic Stress Disorder

United States
Heart of England NHS Trust
University of Birmingham; National Institute for Health Research, United Kingdom

Completed

A Study of Home Monitoring in Adults With Cystic Fibrosis (HOMECF) (HOME-CF)

Cystic Fibrosis

United Kingdom
Foundation for Innovative New Diagnostics, Switzerland
National Institute of Malaria Research, New Delhi, India

Completed

Clinical Evaluation of the STANDARD™ Q Malaria/CRP Duo Test

Fever Malaria

India
New Mexico Cancer Care Alliance
Lovelace Respiratory Research Institute

Active, not recruiting

Expression & Epigenetic Silencing of MicroRNA for Predicting Therapeutic Response and Prognosis of HPV-negative HNSCC

Head and Neck Squamous Cell Carcinoma

United States
New York University
National Institute of Nursing Research (NINR)

Completed

MBSR During AI Therapy for Breast Cancer

Breast Cancer | Cognitive Symptom

United States
JoAnn Harnar
Allergan

Completed

Efficacy and Safety Study of Botulinum Neurotoxin A With Rehabilitation Versus Botulinum Neurotoxin A Alone in Treatment of Post-stroke Spasticity

Upper Limb Spasticity

United States
University of New Mexico
Patient-Centered Outcomes Research Institute

Completed

Comparing Program Options for Latinos With Diabetes

Diabetes Mellitus

United States

Clinical Trials Sponsored by New England Research Institutes

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