Clinical Trials Sponsored by Orthopaedic Research UK

Total 623 results

Anderson Orthopaedic Research Institute
DePuy Orthopaedics

Completed

Comparison of High Flex and Standard Rotating Platform Total Knee Arthroplasty (TKA)

Knee Osteoarthritis
Anderson Orthopaedic Research Institute
DePuy Orthopaedics

Completed

Marathon and Enduron Polyethylene at Long-Term Follow-up

Arthritis | Joint Diseases | Musculoskeletal Diseases | Rheumatic Diseases | Osteoarthritis

United States
Anderson Orthopaedic Research Institute
DePuy Orthopaedics

Completed

A Five-Year Metal-on-Metal Retrospective Clinical Study

Osteoarthritis

United States
Anderson Orthopaedic Research Institute
DePuy Orthopaedics

Completed

Study Comparing Marathon Polyethylene and Enduron Polyethylene Acetabular Liners Used in Total Hip Arthroplasty

Arthritis | Joint Diseases | Musculoskeletal Diseases | Rheumatic Diseases | Osteoarthritis

United States
Anderson Orthopaedic Research Institute
DePuy Orthopaedics

Completed

A Comparison of Wear Among Mobile and Fixed Bearing Knee Replacements

Osteoarthritis

United States
Heekin Orthopedic Research Institute
Stryker Orthopaedics

Completed

Midvastus Versus Medial Parapatellar Approach for Minimally Invasive Total Knee Arthroplasty

Osteoarthritis

United States
Heekin Orthopedic Research Institute
Stryker Orthopaedics

Completed

Anterior Referencing Versus Posterior Referencing in Minimally Invasive Total Knee Arthroplasty (AR vs PR)

Osteoarthritis

United States
Heekin Orthopedic Research Institute
DePuy Orthopaedics; ConforMIS, Inc.; Stryker Orthopaedics

Unknown

Total Hip Registry

Osteoarthritis

United States
Heekin Orthopedic Research Institute
DePuy Orthopaedics; ConforMIS, Inc.; Stryker Orthopaedics

Unknown

Knee Arthroplasty Registry

Osteoarthritis, Knee

United States
Foundation for Orthopaedic Research and Education
Stryker Orthopaedics

Completed

MAKO-Uni-Knee Arthroplasty Clinical Outcomes and Function

Clinical Outcomes

United States
Bournemouth University
Stryker Orthopaedics; Nuffield Health Bournemouth; Orthopaedic Research Institute

Recruiting

An Evaluation of Health Outcomes for Mako Hip Replacement (HELLO)

Osteoarthritis, Hip

United Kingdom
Anderson Orthopaedic Research Institute
DePuy Orthopaedics; Orthopaedic Biomechanics and Biomaterials Laboratory at...

Unknown

Analysis of Crosslinked and Conventional Polyethylene Explants

Osteoarthritis

United States
Orthopaedic Education and Research Institute (dba...
Irrimax Corporation

Recruiting

Wound Irrigation Comparative Effectiveness Study

Wound Irrigation

United States
Anderson Orthopaedic Research Institute
DePuy Orthopaedics; University of Western Ontario, Canada

Completed

Metal Ion Release From an FDA-Approved Metal-on-Metal Total Hip Replacement Implant

Non-inflammatory Degenerative Joint Disease

United States, Canada
Orthopaedic Research Foundation

Completed

Energy Dispersive Bracing for Conservative Treatment of Knee Osteoarthritis

Arthritis | Knee Osteoarthritis

United States
Fraser Orthopaedic Research Society

Completed

INfrapatellar Versus SUprapatellar Reamed Intramedullary Nailing for Fractures of the Tibia (INSURT)

Tibial Fractures | Anterior Knee Pain Syndrome

Canada, Spain
Anderson Orthopaedic Research Institute

Enrolling by invitation

Cemented vs. Cementless Unicompartmental Knee Arthroplasty

Partial Knee Replacement

United States
Anderson Orthopaedic Research Institute

Completed

Knee Arthroplasty Performed With Conventional and Customized Instrumentation (CPI)

Knee Arthritis

United States
Fraser Orthopaedic Research Society

Recruiting

Study Comparing SBS and LRTI for Treatment of CMC Arthritis (SBSvsLRTI)

Arthritis

Canada
Fraser Orthopaedic Research Society

Completed

Immediate Weight-Bearing Ankle Study

Surgery | Ankle Fractures

Canada
Fraser Orthopaedic Research Society

Terminated

PRCT: Ligament Reconstruction & Tendon Interposition With a Joint Spacer for Trapeziometacarpal OA (TMC/PyroDisk)

Joint Disease

Canada
Cancer Research UK
Vaccitech (UK) Limited

Recruiting

A Trial of ChAdOx1 and MVA Vaccines Against MAGE-A3 and NY-ESO-1

Non-small Cell Lung Cancer (NSCLC)

United Kingdom
Fraser Orthopaedic Research Society

Recruiting

Strength After Elbow Fractures in the Elderly (STAND-UP)

Fracture;Elbow

Canada
Fraser Orthopaedic Research Society

Completed

Proximal Humerus Fracture Dislocation Direction and Avascular Necrosis (PHF-D)

Avascular Necrosis | Proximal Humeral Fracture | Avascular Necrosis of Humerus | Dislocation | Dislocation Shoulder

Canada
Anderson Orthopaedic Research Institute

Unknown

Pharmacogenetics for Pain Management in Joint Replacement Patients (PGx)

Arthroplasty Complications

United States
Anderson Orthopaedic Research Institute

Completed

Study of Total Hip Arthroplasty Using Radlink Surgical Positioning Software

Total Hip Replacement
Orthopaedic Research Foundation
OrthoIndy

Completed

A Comparison of INSORB Staples With Metal Staples in Total Hip Replacement

Pain | Erythema | Drainage | Bruising

United States
Fraser Orthopaedic Research Society

Withdrawn

Platelet Rich Plasma Study With Meniscal Repair

Meniscus Lesion

Canada
Fraser Orthopaedic Research Society

Terminated

PRCT: Comparing Two Procedures for Ulno-Carpal Abutment Syndrome. (UAS)

Joint Disease

Canada
Cancer Research UK

Completed

Phase I Study of MOv18 IgE

Human Cancers

United Kingdom
Cancer Research UK

Completed

AST-VAC2 Vaccine in Patients With Non-small Cell Lung Cancer

Advanced Non-small Cell Lung Cancer

United Kingdom
Cancer Research UK

Completed

A Phase I Trial of Anti-GD2 T-cells (1RG-CART)

Relapsed or Refractory Neuroblastoma

United Kingdom
Cancer Research UK

Completed

AT9283 in Children and Adolescents With Relapsed and Refractory Solid Tumors

Unspecified Childhood Solid Tumor, Protocol Specific

United Kingdom
Cancer Research UK

Terminated

A Phase I Study of AZD0424 Alone and in Combination in Advanced Solid Tumours (AZD0424)

Advanced Solid Tumours

United Kingdom
Cancer Research UK

Terminated

NG-Nitro-L-Arginine in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United Kingdom
Cancer Research UK

Terminated

GSAO in Treating Patients With Advanced Solid Tumors That Have Not Responded to Therapy

Unspecified Adult Solid Tumor, Protocol Specific

United Kingdom
Cancer Research UK

Completed

Vaccine Therapy in Treating Patients With Epstein-Barr Virus-Related Cancer

Lymphoma | Head and Neck Cancer | Gastric Cancer | Nonneoplastic Condition | Lymphoproliferative Disorder

United Kingdom
Cancer Research UK

Withdrawn

Comparing PET-CT Using C-11 Choline and 18F-Fluoromethylcholine in Patients With Metastatic Prostate Cancer

Prostate Cancer

United Kingdom
Cancer Research UK

Terminated

AMG 319 in HPV Positive and Negative HNSCC

Human Papillomavirus (HPV) | Positive or Negative Head and Neck Squamous Cell Carcinoma (HNSCC) of the Hypopharynx, Oropharynx, Oral Cavity, Supraglottis or Larynx

United Kingdom
Cancer Research UK

Completed

Olaparib and Temozolomide in Treating Patients With Relapsed Glioblastoma

Brain and Central Nervous System Tumors

United Kingdom
Cancer Research UK

Completed

Abiraterone Acetate in Treating Postmenopausal Women With Advanced or Metastatic Breast Cancer

Breast Cancer

United Kingdom
Cancer Research UK

Completed

Rucaparib(CO-338;Formally Called AG-014699 or PF-0136738) in Treating Patients With Locally Advanced or Metastatic Breast Cancer or Advanced Ovarian Cancer

Breast Cancer | Ovarian Cancer | brca1 Mutation Carrier | brca2 Mutation Carrier

United Kingdom
Cancer Research UK

Completed

AT9283 in Treating Young Patients With Relapsed or Refractory Acute Leukemia

Leukemia

United Kingdom
Cancer Research UK

Completed

A Phase I Study of the Chimeric Anti-CD40 Monoclonal Antibody ChiLob 7/4 to Treat Advanced Malignancies Refractory to Conventional Anti-cancer Treatment

Neoplasms | Lymphoma | Cancer | B-Cell | Non-Hodgkin

United Kingdom
Cancer Research UK

Terminated

Boron Phenylalanine With or Without Mannitol in Treating Patients With Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United Kingdom
Cancer Research UK

Terminated

Technetium Tc 99m Demobesin-4 for Imaging Procedures in Patients With Prostate Cancer

Prostate Cancer

United Kingdom
Cancer Research UK

Terminated

Treated Blood Cells, Cyclophosphamide, Fludarabine Phosphate, and Aldesleukin in Treating Patients With Cancer

Breast Cancer | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific

United Kingdom
Cancer Research UK

Active, not recruiting

A CR-UK Phase I Trial of LY3143921

a. Colorectal Cancer | b. High Grade Serous Ovarian Cancer | c. Non Small-cell Lung Cancer (Squamous Cell Variant) | d. Squamous Carcinoma of the Oesophagus | e. Squamous Carcinoma of the Head and Neck (HPV Negative) | f. Urothelial Cancer | g. Breast Cancer (Triple Negative Type) | h. Pancreatic...

United Kingdom
Cancer Research UK

Completed

A Phase I/II Study of [124I]mIBG PET/CT in Neuroblastoma

Metastatic Neuroblastoma

United Kingdom
Cancer Research UK

Completed

Phase I Study of AT13148, a Novel AGC Kinase Inhibitor

Advanced Solid Tumours

United Kingdom

Clinical Trials Sponsored by Orthopaedic Research UK

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