Clinical Trials Sponsored by PLx Pharma

Total 9411 results

PLx Pharma

Completed

Pharmacodynamic and Pharmacokinetic Study of PL-ASA

Healthy Volunteers

United States
PLx Pharma

Completed

Pharmacodynamic Evaluation of PL2200 Versus Enteric-Coated Aspirin in Diabetic Patients (RITE)

Diabetes Mellitus, Type 2

United States
PLx Pharma

Completed

Pharmacokinetic and Pharmacodynamic Assessment of a Novel, Pharmaceutical Lipid-Aspirin Complex

Bioequivalence
PLx Pharma

Completed

Endoscopic Evaluation of Upper Gastrointestinal (GI) Mucosal Damage Induced by PL-2200 Versus Aspirin in Healthy Volunteers

Upper Gastrointestinal Mucosal Damage

United States
PLx Pharma

Completed

Evaluation of Upper GI Ulceration Induced by PL2200 Versus Aspirin in At-Risk Subjects

Gastroduodenal Ulceration

United States
PLx Pharma

Completed

Randomized, Crossover Bioequivalence Study of PL-ASA Versus Immediate Release Aspirin in Healthy Volunteers.

Bioequivalence

United States
PLx Pharma

Completed

Pharmacodynamic Evaluation of PL2200 Versus Enteric-Coated and Immediate Release Aspirin in Diabetic Patients

Diabetes Mellitus, Type 2

United States
PLx Pharma

Completed

Food-Effect Pharmacokinetic Study of PL2200

Healthy

United States
Herantis Pharma Plc.
Renishaw plc.

Completed

Safety of CDNF by Brain Infusion in Patients With Parkinson's Disease. Extension to HP-CD-CL-2002 Clinical Study

Brain Diseases | Nervous System Diseases | Parkinson Disease | Movement Disorders | Neuro-Degenerative Disease

Sweden, Finland
Herantis Pharma Plc.
Renishaw plc.

Completed

Clinical Study to Test the Safety of CDNF by Brain Infusion in Patients With Parkinson's Disease

Brain Diseases | Nervous System Diseases | Parkinson Disease | Movement Disorders | Neurodegenerative Diseases

Sweden, Finland
Redx Pharma Plc

Recruiting

A Study to Assess Efficacy of RXC004 +/- Nivolumab in Ring Finger Protein 43 (RNF43) or R-spondin (RSPO) Aberrated, Metastatic, Microsatellite Stable, Colorectal Cancer After Progression on Standard of Care (SOC)

Colorectal Cancer

Korea, Republic of, Spain, United States, United Kingdom
Redx Pharma Plc

Active, not recruiting

Study to Evaluate the Safety and Tolerability of RXC004 in Advanced Malignancies

Cancer | Solid Tumor

United Kingdom
4D pharma plc

Withdrawn

Study of MRx0518 and Avelumab in Patients With Urothelial Carcinoma (AVENU)

Urothelial Carcinoma

United States
4D pharma plc

Withdrawn

A Study for Efficacy and Safety of Live Biotherapeutic MRx4DP0004 to Treat COVID-19

COVID-19

United Kingdom
4D pharma plc

Completed

Study of Bacteroides Thetaiotaomicron in Young People Aged 16 to 18 Years With Stable Crohn's Disease

Crohn's Disease

United Kingdom
Verona Pharma plc

Completed

The Effects of RPL554 on Top of Standard COPD Reliever Medications

Chronic Obstructive Pulmonary Disease

United Kingdom
4D pharma plc

Terminated

A Study of MRx-4DP0004 in Asthma

Asthma

United States, United Kingdom
Herantis Pharma Plc.

Active, not recruiting

Clinical Study With Lymfactin® in the Treatment of Patients With Secondary Lymphedema (AdeLE) (AdeLE)

Secondary Lymphedema

Finland, Sweden
4D pharma plc

Terminated

A Study of Live Biotherapeutic Product MRx0518 With Hypofractionated Radiation Therapy in Resectable Pancreatic Cancer

Pancreatic Cancer

United States
Herantis Pharma Plc.

Terminated

A Phase I Study With Lymfactin® in the Treatment of Patients With Secondary Lymphedema

Secondary Lymphedema

Finland
Poolbeg Pharma plc

Completed

Effects of p38 MAPK Inhibitor POLB 001 on in Vivo LPS Challenge Responses

Influenza, Human

Netherlands
Verona Pharma plc

Completed

Dose Ranging Study of RPL554 in Chronic Obstructive Pulmonary Disease (COPD) Patients

COPD

United Kingdom, Poland, Germany, Bulgaria, Czechia, Romania
Verona Pharma plc

Completed

The Effects of RPL554 in Addition to Tiotropium in COPD Patients

Chronic Obstructive Pulmonary Disease Moderate
Destiny Pharma Plc

Completed

Study of the Nasal Decolonisation of Staphylococcus Aureus (SA) and the Safety and Tolerability of XF-73 Nasal Gel in Healthy Subjects

Staphylococcus Aureus Infection

United Kingdom
Verona Pharma plc

Completed

Comparison of RPL554 With Placebo and Salbutamol in Asthmatic Patients

Asthma

Sweden, United Kingdom
Destiny Pharma Plc

Completed

Effect of Exeporfinium Chloride (XF-73) Gel on Nasal S.Aureus in Patients at Risk of Post-op Staphylococcal Infection

Staphylococcal Infections | Surgical Site Infection

United States, Serbia, Georgia
4D pharma plc

Completed

A Trial for New Treatment of Adult Participants With Irritable Bowel Syndrome

Irritable Bowel Syndrome

United States, United Kingdom, Ireland
Verona Pharma plc

Completed

Bronchodilator Effect of RPL554 Administered in Addition to Tiotropium/Olodaterol in Patients With COPD

COPD

United States, United Kingdom
Destiny Pharma Plc

Completed

Study to Assess Eradication of Nasal Carriage of Staphylococcus Aureus (SA) With Mupirocin (Bactroban 2% Nasal Ointment)

Staphylococcal Infection

United Kingdom
Verona Pharma plc

Completed

SAD/MAD Study of a New Formulation of Nebulised RPL554 in Healthy Subjects and COPD Subjects

Chronic Obstructive Pulmonary Disorder | Inflammatory Disorder of the Respiratory Tract

United Kingdom
Verona Pharma Inc

Completed

Pilot Study of Ensifentrine or Placebo Delivered Via pMDI in Hospitalized Patients With COVID-19

Coronavirus Infection | Covid-19 | SARS-CoV-2

United States
LEO Pharma
ICON plc

Completed

A Single and Multiple Ascending-dose Trial of LEO 153339 in Healthy Adults

Healthy Volunteers

Netherlands
Renishaw
Herantis Pharma Plc.

Active, not recruiting

Long-Term Follow-up Safety After DDS Implantation With/Without CDNF Infusions

Brain Diseases | Nervous System Diseases | Parkinson Disease | Movement Disorders | Neuro-Degenerative Disease

Finland, Sweden
Redx Pharma Plc
Simbec Research

Recruiting

Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of RXC007 in Idiopathic Pulmonary Fibrosis

Fibrosis | IPF

Italy, Spain, United States, Belgium, United Kingdom, Austria, Czechia, Poland, Switzerland
Redx Pharma Plc
Simbec Research

Completed

A 3-part Study to Evaluate Safety, Tolerability, Food Effect and Drug-drug Interactions of RXC007 in Healthy Volunteers

Liver Diseases | Fibrosis | Kidney Diseases | Inflammation | Idiopathic Pulmonary Fibrosis | Non-alcoholic Steatohepatitis

United Kingdom
Herantis Pharma Plc.
ORA, Inc.

Completed

Phase 2 Study With Cis-UCA Ophthalmic Solutions in Subjects With Dry Eye

Dry Eye Syndrome

United States
4D pharma plc
ICON plc; Labcorp Drug Development Inc

Withdrawn

Study to Assess the Safety of MRx0029 or MRx0005 Compared to Placebo, in People With Parkinson's

Idiopathic Parkinson Disease
Verona Pharma plc
Iqvia Pty Ltd

Completed

A Phase 3 Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD

Chronic Obstructive Pulmonary Disease

Denmark, United States, Bulgaria, Belgium, Poland, Spain, Canada, Estonia, Hungary, Slovakia
Evgen Pharma
Premier Research Group plc

Completed

SFX-01 in the Treatment and Evaluation of Metastatic Breast Cancer (STEM)

Breast Neoplasm

United Kingdom, Belgium, France, Spain
Verona Pharma plc
Iqvia Pty Ltd

Completed

Study Evaluating 5 Doses of RPL554 and Placebo in COPD Patients Via a Dry Powder Inhaler

Pulmonary Disease, Chronic Obstructive

United States
Verona Pharma plc
Iqvia Pty Ltd

Completed

A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD

Chronic Obstructive Pulmonary Disease

Korea, Republic of, United States, Bulgaria, Czechia, Germany, Greece, Hungary, Poland, Romania, Russian Federation, Slovakia, United Kingdom
Verona Pharma plc
Iqvia Pty Ltd

Completed

A Study of RPL554 Drug Administered by Metered Dose Inhaler to Treat Chronic Obstructive Pulmonary Disease

COPD

United Kingdom
Imperial College London
4D pharma plc

Active, not recruiting

MRx0518 in Patients With Solid Tumours Waiting Surgical Removal of the Tumour (MICROBIOME)

Melanoma | Breast Cancer | Head and Neck Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Bladder Cancer | Renal Cancer | Urethral Cancer | Uterine Cancer

United Kingdom
Verona Pharma plc
Cystic Fibrosis Trust

Completed

A Study of RPL554 in Patients With Cystic Fibrosis

Cystic Fibrosis

United Kingdom
HEM Pharma Inc.
Premier Research Group plc

Not yet recruiting

HEM1036 Phase 2 Study in Low Anterior Resection Syndrome

LARS - Low Anterior Resection Syndrome
Redx Pharma Plc
Merck Sharp & Dohme LLC

Completed

A Study to Assess RXC004 Efficacy in Advanced Solid Tumours After Progression on Standard of Care (SoC) Therapy (PORCUPINE2) (KEYNOTE-E86)

Advanced Solid Tumours

United Kingdom, Australia
Tris Pharma, Inc.
Premier Research Group plc

Completed

Amphetamine Extended-Release Tablets in the Treatment of Adults With ADHD

ADHD

United States
4D pharma plc
Merck Sharp & Dohme LLC

Terminated

Live Biotherapeutic Product MRx0518 and Pembrolizumab Combination Study in Solid Tumors

Melanoma | Renal Cell Carcinoma | Solid Tumor | Non Small Cell Lung Cancer | Bladder Cancer | Oncology

United States
Chinese PLA General Hospital
Roche Pharma AG

Completed

Intrapleural Bevacizumab and Cisplatin Therapy for Malignant Pleural Effusion Caused by Non-small Cell Lung Cancer

Malignant Pleural Effusion

China
Danisco
ICON plc; 4Pharma Ltd.; Daacro

Completed

A Study to Assess the Safety and Efficacy of Probiotic to Modulate Psychological Stress

Healthy | Stress, Psychological

Ireland, United Kingdom

Clinical Trials Sponsored by PLx Pharma

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