Clinical Trials Sponsored by PTEN Research

Total 39634 results

Ohio State University
Pfizer; PTEN Research

Active, not recruiting

Sirolimus for Cowden Syndrome With Colon Polyposis

Cowden Syndrome | Polyposis | PTEN Gene Mutation | PTEN Hamartoma Tumor Syndrome | PTEN Hamartoma Syndrome | Bannayan Syndrome | Bannayan Zonana Syndrome

United States
Laboratorios Poen

Recruiting

Dorzolamide+Timolol Multidose Preservative-free vs Dorzolamida+Timolol BAK Preserved Efficacy and Safety

Ocular Hypertension | Glaucoma, Open-Angle

Argentina
Laboratorios Poen

Completed

Efficacy and Toxicity of Bepotastine 1,5% PF vs Olopatadine 0,2% With BAK on Allergic Conjunctivitis Treatment

Allergic Conjunctivitis

Argentina
Laboratorios Poen

Completed

Difluprednate vs. a Prednisolone Acetate - Phenylephrine on Post-operative Inflammation Following Cataract Surgery.

Cataract

Argentina
Laboratorios Poen

Completed

Efficacy and Tolerability of an Innovative Formulation of BAK-free Latanoprost

Primary Open-angle Glaucoma

Argentina
David VanderWeele

Terminated

Neoadjuvant Androgen Deprivation, Darolutamide, and Ipatasertib in Men With Localized, High Risk Prostate Cancer (ADDItion)

Castrate Resistant Prostate Cancer

United States
Biofourmis Singapore Pte Ltd.
Mundipharma Research Limited

Completed

Continuous Monitoring of Physiology and Self-reported Pain Score Amongst Post-surgical Knee Patients (ObservePAIN)

Knee Arthroplasty

Singapore
Sherif Farag

Withdrawn

Azacitidine Plus Nivolumab Following Reduced-intensity Allogeneic PBSC Transplantation for Patients With AML and High-risk Myelodysplasia

Aml | AML, Adult
Danone Asia Pacific Holdings Pte, Ltd.
Nutricia Research

Completed

New Infant Formula Trial in Healthy Term Subjects on Growth, Body Composition, Tolerance and Safety (Venus)

Healthy

Singapore
Danone Asia Pacific Holdings Pte, Ltd.
Danone Research

Withdrawn

Colonisation Resistance Study (ColoR)

Healthy Infants

Thailand
Geriatric Education and Research Institute
Neeuro Pte Ltd; Ministry of Health, Singapore; ProAge Pte Ltd; KKT Technology Pte...

Completed

Evaluation of Pilot Community-based Multi-domain Program Older Adults at Risk of Cognitive Impairment

Cognitive Decline | Cognitive Impairment, Mild

Singapore
Geriatric Education and Research Institute
Neeuro Pte Ltd

Completed

Evaluation of Implementation and Effectiveness of Computerised Brain Training for Older Adults

Cognition

Singapore
Muhammad Furqan
AstraZeneca

Recruiting

Chemo-Immunotherapy Followed by Durvalumab and Ceralasertib in Treatment Naïve Patients With Extensive Stage Small Cell Lung Cancer

Extensive Stage Small Cell Lung Cancer

United States
Nelson Yee
Ipsen

Active, not recruiting

Liposomal Irinotecan in Combination With Oxaliplatin, Leucovorin, and 5-fluorouracil for Patients With Locally Advanced Pancreatic Carcinoma:

Locally Advanced Pancreatic Carcinoma(LAPC)

United States
Danone Asia Pacific Holdings Pte, Ltd.
Nutricia Research

Terminated

Meal Tolerance Trial in Pregnant Women Diagnosed With Gestational Diabetes Mellitus. (GDM-MTT)

Gestational Diabetes Mellitus in Pregnancy

Singapore
Dwight Owen
Genentech, Inc.

Recruiting

Temozolomide and Atezolizumab as Second or Third Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Extensive Stage Lung Small Cell Carcinoma | Metastatic Lung Small Cell Carcinoma | Recurrent Lung Small Cell Carcinoma

United States
John Quigley
Pfizer; AbbVie

Active, not recruiting

Study of the Safety and Efficacy of Gemtuzumab Ozogamicin (GO) and Venetoclax in Patients With Relapsed or Refractory CD33+ Acute Myeloid Leukemia:Big Ten Cancer Research Consortium BTCRC-AML17-113

Acute Myeloid Leukemia

United States
Clinical Nutrition Research Centre, Singapore
Barilla Singapore Pte Ltd

Completed

Glycemic and Insulinemic Response of Pasta Products in Comparison to Asian Foods

Diabetes

Singapore
Monika Joshi, MD
AstraZeneca

Active, not recruiting

Durvalumab And Radiation Therapy Followed by Adjuvant Durvalumab in Patients With Urothelial Cancer (T2-4 N0-2 M0) of the Bladder (DUART)

Urothelial Cancer

United States
PranaQ Pte. Ltd.

Recruiting

TipTraQ Home Sleep Test Validation Study

Obstructive Sleep Apnea

United States
Nalagenetics Pte Ltd

Recruiting

Implementation of Pre-emptive Pharmacogenomics Testing in Singapore-based Private Hospital Institutions (PPT Study)

Pre-emptive Pharmacogenomics

Singapore
Moleac Pte Ltd.

Recruiting

MLC1501 Study Assessing Efficacy in Post STrOke Subjects With mOtor Deficits (MAESTOSO)

Stroke | Stroke, Ischemic | Stroke Sequelae | Stroke, Cardiovascular | Strokes Thrombotic | Stroke, Embolic | Stroke, Cryptogenic

Singapore, Philippines
Respiree Pte Ltd

Completed

Respiratory Rate Validation Study - RS001.2 Respiree Cardio-Respiratory Monitor

A Minimum of 30 Adults, Ages 18 Years and Older

United States
Respiree Pte Ltd

Completed

Accuracy of Pulse Oximeters With Profound Hypoxia

Healthy Volunteers

United States
Tychan Pte Ltd.

Completed

Safety of TY027, a Treatment for COVID-19, in Humans

Coronavirus Disease-2019 (COVID-19)

Singapore
H Scott Boswell
Takeda

Terminated

Study Augmenting TAK-659 Action in Relapsed/Refractory AML by Addition Ofthe Proteasome Inhibitor Ixazomib

AML | AML, Adult

United States
Nasser Hanna
Genentech, Inc.

Terminated

Carboplatin Plus Pemetrexed Plus Atezolizumab Plus Bevacizumab in Chemotherapy and Immunotherapy-naïve Patients With Stage IV Non-squamous Non-small Cell Lung Cancer

NSCLC Stage IV | NSCLC, Recurrent

United States
F-star Therapeutics, Inc.
CSI Medical Research Pte Ltd

Terminated

Evaluating the Effects of Inarigivir on Immune Response and Viral Markers in Chronic Hepatitis B Patients

Hepatitis B | Hepatitis B, Chronic | HBV

Singapore
Clinical Nutrition Research Centre, Singapore
Prince September Pte. Ltd.

Recruiting

Singapore Healthy Alternative Protein Evaluation Study (SHAPES)

Cardiovascular Diseases | Diabetes Mellitus | Protein Metabolism Disorder

Singapore
Nasser Hanna
Genentech, Inc.

Recruiting

Adjuvant Treatment With Cisplatin-based Chemotherapy Plus Concomitant Atezolizumab in Patients With Stage I (Tumors ≥ 4cm), IIA, IIB, and Select Stage III [Any T1-3 N1-2 and T4N0-2] Resected Non-small Cell Lung Cancer (NSCLC) and the Clearance of Circulating Tumor DNA (ctDNA)

NSCLC | Lung Cancer

United States
Oana Danciu, MD
Pfizer; Big Ten Cancer Research Consortium

Active, not recruiting

Palbociclib in Combination With Tamoxifen as First Line Therapy for Metastatic Hormone Receptor Positive Breast Cancer

Metastatic Breast Cancer | Hormone Receptor Positive Malignant Neoplasm of Breast | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Estrogen Receptor Positive Breast Cancer | Progesterone Receptor Positive Tumor

United States
Ajjai Alva, MD
AstraZeneca; Big Ten Cancer Research Consortium

Active, not recruiting

Study of Durvalumab and Guadecitabine in Advanced Kidney Cancer

Kidney Cancer | Clear Cell Renal Cell Carcinoma | Advanced Kidney Cancer

United States
Moleac Pte Ltd.

Recruiting

CognivAiD Real-World Evidence Clinical Registry (CONNECT Registry) (CONNECT)

Dementia, Vascular | Memory Impairment

Singapore
Moleac Pte Ltd.

Not yet recruiting

MLC1501 Study Assessing Efficacy in STROke Recovery (MAEStro)

Stroke | Stroke, Ischemic | Stroke Sequelae | Stroke, Cardiovascular | Strokes Thrombotic | Stroke, Embolic | Stroke, Cryptogenic
Moleac Pte Ltd.

Completed

Spinal Cord Injury - Assessing Tolerability and Use of Combined Rehabilitation and NeuroAiD (SATURN)

Spinal Cord Injury

Malaysia
Moleac Pte Ltd.

Completed

NeuroAiD II™ (MLC901) in Mild Traumatic Brain Injury (SAMURAI)

Traumatic Brain Injury

Russian Federation
Nalagenetics Pte Ltd

Completed

Tamoxifen Dose Adjustment on Indonesian Female ER+ Breast Cancer Patients Based on CYP2D6 Genotype and Endoxifen Levels

ER+ Breast Cancer

Indonesia
Mundipharma Pte Ltd.

Terminated

Efficacy and Safety of MedifoamⓇ and BetafoamⓇ in Pressure Ulcer

Pressure Ulcer

Korea, Republic of
BioSyngen Pte Ltd

Unknown

A Study of Syngenon (BSG-001) for Inhalation in Subjects With Malignant Pleural Effusion and/or Malignant Ascites

Malignant Ascites | Malignant Pleural Effusion

Australia
Mundipharma Pte Ltd.

Completed

Analgesic Treatment for Cancer Pain in South East Asia (ACE)

Pain
Moleac Pte Ltd.

Completed

Study of NeuroAid In Enhancing Recovery After Stroke (TIERS)

Stroke | Cerebral Infarction

Singapore
BioSyngen Pte Ltd

Not yet recruiting

A Phase 1 Study of BRG01 in Subjects With Relapsed/Metastatic Epstein-Barr Virus (EBV)-Positive Nasopharyngeal Carcinoma

EBV-positive Nasopharyngeal Carcinoma

China
MiRXES Pte Ltd

Recruiting

Project CADENCE (CAncer Detected Early caN be CurEd) (CADENCE)

Breast Cancer | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Prostate Cancer | Thoracic Cancer | Liver Cancer

Singapore
Biorithm Pte Ltd

Completed

This Clinical Study Evaluates the Performance and Safety of Biorithm Research Kit Versus CTG in Prenatal Monitoring of Pregnant Participants.

Pregnancy

United Kingdom
Tychan Pte Ltd.

Terminated

Efficacy and Safety of TY027, a Treatment for COVID-19, in Humans

Coronavirus Disease-2019 (COVID-19)

Singapore
Tysana Pte Ltd

Completed

Safety and Tolerability of an Antibody Against Yellow Fever Virus (TY014) in Humans

Treatment of Acute Yellow Fever Virus Infection

Singapore
Göteborg University
The Sten A Olsson foundation for Research and Culture

Completed

The Effects of a Rhythm and Music-based Therapy Program and Therapeutic Riding in Late Recovery Phase Following Stroke

Stroke

Sweden
Kari Wisinski
Pfizer; Celcuity Inc

Active, not recruiting

Gedatolisib Plus Talazoparib in Advanced Triple Negative or BRCA1/2 Positive, HER2 Negative Breast Cancers

TNBC - Triple-Negative Breast Cancer

United States
Clinical Nutrition Research Centre, Singapore
Prince September Pte Ltd Singapore

Completed

Energy and Nutrient Profiles When Asians Transit From a Meat-based to a Plant-based Diet: A Modelling Exercise

Nutrition, Healthy

Singapore
Kathy Miller
Millennium Pharmaceuticals, Inc.; Big Ten Cancer Research Consortium

Terminated

MLN0128 Compared to Sorafenib in Advanced or Metastatic Hepatocellular Carcinoma

HCC | Hepatocellular Carcinoma | Liver Cancer

United States

Clinical Trials Sponsored by PTEN Research

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