Clinical Trials Sponsored by Parexel International Ltd

Total 286 results

Debiopharm International SA
Parexel

Completed

A Study of Debio 025 (Alisporivir) Combined With Peg-IFNα2a and Ribavirin in Treatment naïve Chronic Hepatitis C Genotype 1 Patients

Chronic Hepatitis C

Spain, Belgium, Germany, Romania, France, Poland, Italy
Exvastat Ltd.
Parexel

Completed

A Study to Investigate the Effects of Imatinib on Pulmonary Vascular Dysfunction in a Human Model of Lung Injury

Acute Lung Injury

United Kingdom
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Bioequivalence Study of Two Nitisinone Formulations Compared to Orfadin

Hereditary Tyrosinemia, Type I

South Africa
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Bioavailability Food-Effect Study of an Oral Nitisinone Formulation to Treat Hereditary Tyrosinemia (HT-1)

Hereditary Tyrosinemia, Type I

South Africa
Bioblast Pharma Ltd.
Parexel

Completed

A Study to Establish Safety and Maximum Tolerated Dose of IV Trehalose in Healthy Subjects

Healthy Volunteer Subjects

United States
Synairgen Research Ltd.
Parexel

Completed

Pilot Test of COVID-19 Related Clinical Outcome Assessment Methodology and Qualitative Evidence of Content Validity

COVID-19

United States, United Kingdom
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride

Acute Intermittent Porphyria | Anti-Psychotic | Management of Manifestations of Psychotic Disorders | Treatment of Schizophrenia | Control Nausea and Vomiting | Relief of Restlessness and Apprehension Before Surgery | Adjunct in the Treatment of Tetanus | Control Manifestations of the Manic Type... and other conditions

South Africa
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Bioequivalence Study of Two Oral Nitisinone Formulations to Treat Hereditary Tyrosinemia (HT-1)

Hereditary Tyrosinemia, Type I

South Africa
Luye Pharma Group Ltd.
Parexel

Completed

A Pharmacokinetic Similarity Study in Healthy Male Subjects to Evaluate Pharmacokinetics, Pharmacodynamics, Safety and Immunogenicity of LY06006 Versus US-Prolia and EU-Prolia by Single-dose Subcutaneous Injection

Healthy

Germany
Luye Pharma Group Ltd.
Parexel

Completed

A Study to Evaluate the Effectiveness and Safety of LY03003 in Patients With Early Primary PD

Parkinson Disease

China
Futura Medical Developments Ltd.
Parexel

Completed

Assess the Efficacy and Safety in Volunteers of DCF100, TIB200 and SPR300 vs. Placebo and Control(s) in a UV Pain Model

Pain

United Kingdom
Neopharma Japan Co., Ltd.
Parexel

Withdrawn

A Study to Assess the Safety and Efficacy of 5-aminolevulinic Acid Hydrochloride (5-ALA HCl) and Sodium Ferrous Citrate (SFC) Added on Artemisinin-based Combination Therapy (ACT) in Adult Patients With Uncomplicated Malaria

Malaria
Intra-IMMUSG Pte Ltd
Parexel

Recruiting

A Study to Assess Safety and Efficacy of PRL3-Zumab in Patients With Solid Tumors

Solid Tumor

United States
Ono Pharmaceutical Co. Ltd
Parexel

Completed

A First in Human Study to Assess the Safety, Tolerability and Pharmacokinetics of ONO-2808-01 in Healthy Participants

Neurodegenerative Diseases

United Kingdom
AstraZeneca
Parexel; George Clinical Pty Ltd

Terminated

A Study to Evaluate the Safety and Efficacy of AZD5718 in Participants With Proteinuric Chronic Kidney Disease

Chronic Kidney Disease

United States, Taiwan, Germany, Hungary, Malaysia, Japan, Israel, Poland, Brazil, Ukraine, Argentina
Guangzhou Sinogen Pharmaceutical Co., Ltd
Parexel

Recruiting

Study of SGN1 Administered Via Intratumoral Injection in Patients With Advanced Solid Tumor

Advanced Solid Tumor

China, Taiwan
IlDong Pharmaceutical Co Ltd
Parexel; YUNOVIA CO.,LTD.

Recruiting

Safety, Tolerability, and Pharmacokinetics of ID119031166M With the Exploration of Pharmacodynamic Effects

Healthy Participants

United States
UCB Japan Co. Ltd.
Parexel

Completed

Open-label Study to Evaluate the Safety and Tolerability of iv Lacosamide in Japanese Adults With Partial-onset Seizures

Epilepsy | Partial-onset Seizures

Japan
Vitaflo International, Ltd

Recruiting

Evaluation of the Express Plus Range (express plus)

Phenylketonurias | PKU | Maple Syrup Urine Disease | Homocystinuria | Glutaric Acidemia I | Hereditary Tyrosinemia

United Kingdom
Vitaflo International, Ltd

Completed

A Multicenter Study to Evaluate the Nutritional Suitability of Renastart (Renastart)

Chronic Kidney Disease | Hyperkalemia

Germany
Vitaflo International, Ltd

Completed

Evaluation of ZestiVits in Children and Adults on a Ketogenic or Restricted Therapeutic Diet (ZestiVits)

Deficiency of Micronutrients

United Kingdom
Vitaflo International, Ltd

Active, not recruiting

Evaluation of PKU Explore France

Phenylketonurias

France
Vitaflo International, Ltd

Active, not recruiting

Evaluation of TYR Sphere in France (TYR sphere Fra)

Tyrosinemia | AKU

France
Biomedis International Ltd.

Unknown

Recurrent Stroke Prevention Clinical Outcome Study (RESPECTS)

Stroke | Hypertension | Blood Pressure

Japan
Jiangsu ProteLight Pharmaceutical & Biotechnology...
Parexel

Not yet recruiting

Phase II Study to Evaluate Efficacy and Safety of AMP Peptide PL-5 in Mild Infections of Diabetic Foot Ulcers (PL-5)

Diabetic Foot Ulcers

United States
AstraZeneca
PPD; Parexel; Covance; Iqvia Pty Ltd

Completed

PK/PD and Long Term Safety Study of Benralizumab in Children With Severe Eosinophilic Asthma (TATE)

Severe Uncontrolled Asthma

United States, Japan
Lannett Company, Inc.
Parexel; FARMOVS (Pty) Ltd

Completed

A Study to Demonstrate Pharmacokinetic and Pharmacodynamic Biosimilarity Between HEC-Glargine and US-Lantus® in Healthy Male Volunteers

Type 2 Diabetes Mellitus | Type 1 Diabetes Mellitus

South Africa
Linepharma International LTD

Recruiting

Effectiveness and Safety of Combination Mifepristone/Misoprostol for Medical Abortion (MiMAC)

Medical Abortion

Canada
Vitaflo International, Ltd

Completed

Evaluation of PKU Start (PKU Start)

Phenylketonuria | Inborn Errors of Metabolism

United Kingdom
Vitaflo International, Ltd

Completed

Evaluation of Renastep (Renastep)

Chronic Kidney Diseases | Renal Disease

United Kingdom
Vitaflo International, Ltd

Withdrawn

Evaluation of Krio in Children and Adults With Epilepsy (Krio)

Epilepsy | Glucose Transporter Type 1 Deficiency Syndrome | Ketogenic Dieting
Vitaflo International, Ltd

Completed

Evaluation of PKU Sphere in Italy

Phenylketonurias | PKU

Italy
Vitaflo International, Ltd

Completed

Evaluation of PKU Sphere Liquid

Phenylketonurias

United Kingdom
Vitaflo International, Ltd

Completed

Use of Betashot in Children and Adults With Epilepsy

Nervous System Disorder

United Kingdom
Vitaflo International, Ltd

Completed

Evaluation of TYR Sphere

Alkaptonuria | Tyrosinemias | Tyrosinemia, Type I | Tyrosinemia, Type II | Tyrosinemia, Type III

United Kingdom
Vitaflo International, Ltd

Completed

Evaluation of Keyo in Children With Epilepsy (Keyo)

Intractable Epilepsy | Glucose Transporter Type 1 Deficiency Syndrome | Ketogenic Dieting

United Kingdom
Vitaflo International, Ltd

Completed

Evaluation of Ketoflo (Ketoflo)

Glucose Transporter Type 1 Deficiency Syndrome | Ketogenic Dieting | Epilepsy Intractable

United Kingdom
Maxygen Holdings Ltd.
Parexel; Maxygen ApS; Maxygen, Inc.

Unknown

Evaluation of Maxy-G34 in Breast Cancer Patients Treated With TAC (Docetaxel, Adriamycin, Cyclophosphamide) Chemotherapy

Breast Cancer | Chemotherapy-Induced Neutropenia

Poland, Romania, Russian Federation, Ukraine
TaiGen Biotechnology Co., Ltd.
PPD; Parexel; Qualitix Clinical Research Co., Ltd.

Completed

Study to Evaluate the Efficacy and Safety of Oral Administration With Nemonoxacin and Levofloxacin in Patients With CAP

Pneumonia

Taiwan, China
AstraZeneca
Parexel; Iqvia Pty Ltd; Medidata Solutions; CISCRP

Active, not recruiting

Durvalumab Long-Term Safety and Efficacy Study (WAVE)

Solid Tumor

Spain, United Kingdom, United States, Canada, Czechia, Poland, Romania, Thailand, Vietnam, Belgium, France, Korea, Republic of, Brazil, Hungary, Japan, Russian Federation, Malaysia, Taiwan, Australia, Germany, Turkey, Ukraine, Nethe... and more
Gilead Sciences
Parexel; Iqvia Pty Ltd; Medidata Solutions

Active, not recruiting

Asian Study of Sacituzumab Govitecan (IMMU-132) in HR+/HER2- Metastatic Breast Cancer (MBC)

Metastatic Breast Cancer

Korea, Republic of, Taiwan, China
Guangzhou HuiBoRui Biological Pharmaceutical Technology...
Parexel

Unknown

Clinical Evaluation of Safety and Tolerability of KDR2-2 Eye Drops in Healthy Volunteers With Pharmacokinetic Assessment

Corneal Neovascularization

United States
MSD Wellcome Trust Hilleman Laboratories Pvt. Ltd.
Parexel

Completed

Safety, Reactogenicity and Immunogenicity of Heat-stable Rotavirus Vaccine (HSRV) in Adults and Infants (HSRV)

Rotavirus Gastroenteritis

Bangladesh
Pfizer
Parexel; SACT INTERNATIONAL Co., LTD.; Acronet; Bellsystem24 , Inc.; Mitsubishi Kagaku... and other collaborators

Completed

Dalacin-T Gel Post Approval Study

Acne Vulgaris
Telix International Pty Ltd

Recruiting

External Beam Therapy With Theranostic Radioligand Therapy for Oligometastatic Prostate Cancer (ProstACT TARGET)

Prostate Cancer

Australia
Telix International Pty Ltd

Completed

177Lu-DOTA-TLX591 Safety, Biodistribution and Dosimetry Study (ProstACTSelect)

Metastatic Prostate Cancer

Australia
Telix International Pty Ltd

Not yet recruiting

177Lu-DOTA-rosopatamab With Best Standard of Care (SoC) for the Second Line of Treatment for Metastatic Castrate-resistant Prostate Cancer, Which Expresses PSMA (PROSTACT)

Metastatic Prostate Cancer
Telix International Pty Ltd

Completed

131I-IPA and Concurrent XRT in Recurrent GBM (IPAX-1)

Glioblastoma Multiforme

Austria, Australia, Netherlands
Medtentia International Ltd Oy

Terminated

Study on Safety and Performance of Medtentia Mitral Valve Repair System in Surgical Repair of Mitral Regurgitation

Mitral Regurgitation | Mitral Insufficiency

Finland
Schwabe-Wenex International Ltd

Completed

a Clinical Trial to Evaluate the Efficacy and Safety of Agnucaston Tablets in the Treatment of Premenstrual Syndrome (PMS) (ACT-RCT-C 01)

Premenstrual Syndrome

China

Clinical Trials Sponsored by Parexel International Ltd

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Czech Republic

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Rare Diseases

Drug Interventions

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