Clinical Trials Sponsored by Polaris Group

Total 11041 results

Polaris Group

Recruiting

ADI-PEG 20 Plus Radiotherapy and Temozolomide in Subjects With Glioblastoma Multiforme (GBM)

Glioblastoma Multiforme (GBM)

Taiwan
Polaris Group

Terminated

Ph 1-2 Study ADI-PEG 20 Plus FOLFOX in Subjects With Advanced GI Malignancies Focusing on Hepatocellular Carcinoma

Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Advanced Gastrointestinal (GI) Malignancies

United States, Taiwan, Korea, Republic of, United Kingdom, China, Italy
Polaris Group

Completed

Ph 1B Trial With ADI-PEG 20 Plus Nab-Paclitaxel and Gemcitabine in Subjects With Pancreatic Cancer

Advanced Pancreatic Cancer

United States
Polaris Group

Completed

Ph 2 Trial of ADI PEG 20 Plus Concurrent Transarterial Chemoembolization (TACE) Vs TACE Alone in Patients With Unresectable Hepatocellular Carcinoma (TACE)

Unresectable Hepatocellular Carcinoma

Taiwan
Polaris Group

Completed

Ph 1 Study of ADI PEG 20 in Pediatric Subjects Who Are Argininosuccinate Synthetase (ASS) Deficient

Argininosuccinate Synthetase Deficient

United States
Polaris Group

Recruiting

Study of ADI-PEG 20 Versus Placebo in Subjects With High Arginine Level and Unresectable Hepatocellular Carcinoma

Hepatocellular Carcinoma | Advanced Hepatocellular Carcinoma

Taiwan, Vietnam
Polaris Group

Terminated

Study ADI-PEG 20 Plus Pembrolizumab in Advanced Solid Cancers

Advanced Solid Cancers

Taiwan
Polaris Group

Completed

PH 2 ADI-PEG 20 Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States, Taiwan
Polaris Group

Completed

Ph 3 ADI-PEG 20 Versus Placebo in Subjects With Advanced Hepatocellular Carcinoma Who Have Failed Prior Systemic Therapy (ADI-PEG 20)

Hepatocellular Carcinoma

United States, Korea, Republic of, Taiwan, Italy, United Kingdom, China
Polaris Group

Completed

Ph 1 Trial of ADI-PEG 20 Plus Docetaxel in Solid Tumors With Emphasis on Prostate Cancer and Non-Small Cell Lung Cancer

Prostate Cancer | Solid Tumors

United States
Polaris Group

Completed

Ph 1 ADI-PEG 20 Plus Doxorubicin; Patients With HER2 Negative Metastatic Breast Cancer

HER2 Negative Metastatic Breast Cancer

United States
Polaris Group

Recruiting

Study of ADI-PEG 20 Versus Placebo in Subjects With NASH

Nonalcoholic Steatohepatitis (NASH)

Taiwan
Polaris Group

Recruiting

Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)

Soft Tissue Sarcoma

United States
Polaris Group

Recruiting

Study of ADI-PEG 20, Venetoclax and Azacitidine in Acute Myeloid Leukemia

Acute Myeloid Leukemia, Adult

United States
Polaris Group

Completed

Ph 2/3 Study in Subjects With MPM to Assess ADI-PEG 20 With Pemetrexed and Cisplatin (ATOMIC)

Mesothelioma

United States, United Kingdom, Taiwan, Australia, Italy
Polaris Group

Terminated

Ph 1 Study in Subjects With Tumors Requiring Arginine to Assess ADI-PEG 20 With Pemetrexed and Cisplatin (TRAP)

Glioma | Hepatocellular Carcinoma | Uveal Melanoma | Sarcomatoid Carcinoma | Pleural Mesothelioma Malignant Advanced | Peritoneal Mesothelioma Malignant Advanced | Non-squamous Non-small Cell Lung Carcinoma

United States, United Kingdom
Polaris Group

Terminated

Ph 1 Study of ADI-PEG 20 Plus Low Dose Cytarabine in Older Patients With AML

Acute Myeloid Leukemia

Taiwan
Polaris Group

Completed

PH 2 ADI-PEG 20 Study in Non-Hodgkin's Lymphoma Subjects Who Have Failed Prior Systemic Therapy

Non-Hodgkin's Lymphoma

Taiwan
Polaris Group

Completed

Ph 1 Trial of ADI PEG 20 Plus Sorafenib to Treat Patients With Liver Cancer

Hepatocellular Carcinoma

United States
Polaris Group

Completed

Ph 1 Trial of ADI-PEG 20 Plus Cisplatin in Patients With Metastatic Melanoma

Cutaneous Melanoma, Uveal Melanoma, Ovarian Carcinoma or Other Advanced Solid Tumors

Taiwan, United States
Washington University School of Medicine
Polaris Group

Recruiting

Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma

Soft Tissue Sarcoma | Sarcoma,Soft Tissue | Sts

United States
Washington University School of Medicine
Polaris Group

Recruiting

ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers

Small Cell Lung Carcinoma | Non Small Cell Lung Cancer | Non-small Cell Lung Cancer | Small-cell Lung Cancer

United States
Queen Mary University of London
Hoffmann-La Roche; Polaris Group

Withdrawn

Study in Patients With Tumours Requiring Arginine to Assess ADI-PEG 20 With Atezolizumab, Pemetrexed and Carboplatin (iTRAP)

Carcinoma, Non-Small-Cell Lung
Groupe Hospitalier Paris Saint Joseph

Recruiting

Assessing Women's Preferences for Postpartum Thromboprophylaxis: the PREFER-PostPartum (PREFER-PP)

Pregnancy

France
Groupe Hospitalier Paris Saint Joseph

Recruiting

Percutaneous Treatment of Iatrogenic False Femoral Aneurysms by Ultrasound-guided Thrombin Injection (EGTI)

Femoral; Aneurysm

France
Groupe Hospitalier Paris Saint Joseph

Recruiting

Prospective Cohort of Patients With Critical Limb Ischemia Undergoing Revascularization (CLI ENDOVASC)

Critical Limb Ischemia

France
Groupe Hospitalier Paris Saint Joseph

Active, not recruiting

Cardiac Thrombus in Early Cardiac CT Scan in Etiological Workup of Ischemic Stroke: Prospective Study (CCT STROKE)

Stroke

France
Groupe Hospitalier Paris Saint Joseph

Completed

Evaluation of the Impact of the XEN® Implant on Endothelial Cell Density, 3 Years After Surgery (RETROXEN)

Glaucoma

France
Groupe Hospitalier Paris Saint Joseph

Completed

Evaluation of the Efficacy of Selecta Laser Trabeculoplasty in Patients Undergoing Filtering Surgery (SLT)

Glaucoma

France
Groupe Hospitalier Paris Saint Joseph

Active, not recruiting

Anatomical and Functional Assessment of Ex-vivo Coronary Perfusion (ECHORONEX)

Cardiac Transplantation

France
Groupe Hospitalier Paris Saint Joseph

Completed

Effectiveness of an Exercise Re-training Program on Dyspnea in Patients After Acute Respiratory Distress Syndrome Secondary to Severe COVID-19 Pneumonia in Post-ICU (RECOVER)

Dyspnea

France
Groupe Hospitalier Paris Saint Joseph

Completed

Comparison of Fissurectomy to Fissurectomy With Anoplasty (ANOFIS)

Fissure Rectal

France
Groupe Hospitalier Paris Saint Joseph

Terminated

Kinesio Taping and Manual Therapy Efficacity on Lumbar Pain During Pregnancy

Manual Therapy

France
Groupe Hospitalier Paris Saint Joseph

Active, not recruiting

OCT Angiography in the Glaucoma Diagnosis (OCTA)

Glaucoma

France
Groupe Hospitalier Paris Saint Joseph

Completed

Study "HEMORROIDAL SURGERY AND Chronic Inflammatory Bowel Disease" (CHRMICI)

Hemorrhoids | Chronic Inflammatory Bowel Disease

France
Groupe Hospitalier Paris Saint Joseph

Active, not recruiting

Evaluation of Medical Care and Patient's Knowledge About the Behavior to Take on Secondary Prevention of Anaphylaxis

Anaphylaxis

France
Groupe Hospitalier Paris Saint Joseph

Completed

Development of a Predictive Algorithm for the Risk of Rehospitalization of Patients With Heart Failure

Heart Failure

France
Groupe Hospitalier Paris Saint Joseph

Completed

Evaluation of the Implementation of Neonatal Phototherapy With BiliCocoon® in Maternity Wards (BiliCocoon)

Neonatal Phototherapy

France
Groupe Hospitalier Paris Saint Joseph

Completed

Validation of Hemorrhoidal Bleeding Score

Hemorrhoid Bleeding

France
Groupe Hospitalier Paris Saint Joseph

Completed

Interest of the Second Phase of the Oral Challenge Test in Patients With Suspected Long-standing Penicillin Allergy (PENI)

Allergy Penicillin

France
Groupe Hospitalier Paris Saint Joseph

Completed

Evaluation of the Modalities of Administration of Synthetic Oxytocin During Spontaneous Labor (LAMA)

Oxytocin

France
Groupe Hospitalier Paris Saint Joseph

Completed

Is There a Place for Pre-operative Temporary Embolization of Uterine Fibroids (EMBOFIB)

Uterine Fibroid

France
Groupe Hospitalier Paris Saint Joseph

Active, not recruiting

Study of Left Ventricular Function of Patients With Type 2 Diabetes Without Cardiovascular Disease (DIACAR)

Type2 Diabetes

France
Groupe Hospitalier Paris Saint Joseph

Active, not recruiting

Feasibility Study on an Immersive Virtual Reality Tool in the Treatment of Chronic Low Back Pain (RIVAGE)

Chronic Low-back Pain

France
Groupe Hospitalier Paris Saint Joseph

Completed

Impact of Iron Infusion in Anemic Patients on Their Postoperative Outcome After Colorectal Surgery (IRON_PREHAB)

Colorectal Surgery | Anemia, Iron Deficiency

France
Groupe Hospitalier Paris Saint Joseph

Completed

Clinical Impact of Rapid AST Directly From Blood Cultures (MHR-BC)

Bacterial Infections

France
Groupe Hospitalier Paris Saint Joseph

Completed

Predictors of Non-accESs to therapeutiC EducAtion Programs Among Patients With Type 2 Diabetes, and/or Asthma, and/or Chronic Heart Failure in an Emergency Setting (ESCAPE)

Heart Failure | Diabetes | Emergencies | Asthma | Therapeutic Education Program

France
Groupe Hospitalier Paris Saint Joseph

Active, not recruiting

Evaluation of Pharmacokinetic / Pharmacodynamic Data and Interest Individualized Therapeutic Drug Monitoring Glycopeptides and β-lactam-aminoglycoside ICU

Severe Infection

France
Groupe Hospitalier Paris Saint Joseph

Completed

Multicenter Evaluation of the Susceptibility of Enterobacteriaceae and Pseudomonas Aeruginosa to Ceftolozane/Tazobactam Combination (GMC-9)

Antibiotic Resistant Strain

France
Groupe Hospitalier Paris Saint Joseph

Completed

Pelvic Ring Fractures: New Analysis Method and Treatment Decision Algorithm (BASSINJO)

Pelvic Fracture

France

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