Clinical Trials Sponsored by Public Health England (PHE)

Total 408 results

Public Health England

Completed

CMO Letter to Reduce Unnecessary Antibiotic Prescribing March 2018

Prescribing, Off-Label

United Kingdom
Public Health England

Completed

A Study to Gather Safety Data Following Administration of a Hib-containing Booster Vaccine in Children Aged Two to Five Years (DIPS)

Haemophilus Infections

United Kingdom
Public Health England

Completed

A Study to Assess the Carriage of Pneumococci in Children Aged 1-5 Years, and Their Household Contacts (PIN)

Nasal Carriage of Pneumococci

United Kingdom
Public Health England

Completed

Evaluation of the Immunogenicity and Reactogenicity of a Pneumococcal Conjugate Vaccine in Healthy Adults

Streptococcus Pneumoniae
Public Health England

Withdrawn

Childhood Influenza Immunisation Invitation Trial in Schools

Influenza, Human
Public Health England

Completed

Response of United Kingdom (UK) Infants to a Reduced Primary Schedule With Meningococcal C and Pneumococcal Conjugate Vaccines (sched1)

Pneumococcal Infections | Meningococcal Infections

United Kingdom
Public Health England

Completed

Comparison of Two Meningococcal ACWY Conjugate Vaccines (PRIME)

Meningococcal Meningitis

United Kingdom
Public Health England

Completed

CMO Letter to Reduce Inappropriate Antibiotic Prescribing Winter 2019/2020

Prescribing, Off-Label

United Kingdom
Public Health England

Completed

PRIME Follow up - Quadri Meningo Vacinees (PRIMEfollowup)

Meningococcal Disease
Public Health England

Completed

CMO Letter to Reduce Unnecessary Antibiotic Prescribing and Broad Spectrum Prescribing Winter 2018-9 (CMO2018-9)

Prescribing, Off-Label

United Kingdom
Public Health England

Completed

Immunogenicity of a Reduced Primary Schedule for Pneumococcal Conjugate Vaccine in UK Infants

Streptococcus Pneumoniae
Public Health England

Withdrawn

Host-pathogen Interactions in Meningococcal Disease: Finding the Key That Fits the Lock (Lock and Key)

Meningitis

United Kingdom
Public Health England

Completed

A Study to Validate a New Oral Fluid/Saliva Antibody Test for Novel H1N1v Influenza (Snuffles)

H1N1 Virus
Public Health England

Completed

Reactogenicity Study of Cervarix and Gardasil in UK Adolescent Girls (HPV CSP01)

HPV Infections

United Kingdom
Public Health England

Withdrawn

Ethnicity Data in HIV Positive Men Who Have Sex With Men

HIV

United Kingdom
Public Health England

Completed

Randomized Controlled Trial on Uptake of NHS Health Checks

Cardiovascular Diseases

United Kingdom
Public Health England

Completed

A Study to Assess the Carriage of Pneumococci in Children Aged ≤8 Years, and Their Household Contacts (PIN2)

Immunization; Infection

United Kingdom
Public Health England

Completed

Assessment of Viral Shedding in Children Previously in Receipt of Multiple Doses of Live Attenuated Influenza Vaccine (LAIV) Compared to Influenza Vaccine-naïve Controls (Flushed)

Influenza | Vaccination | Influenza Vaccination

United Kingdom
Public Health England

Completed

Observational Follow up of Prior HPV Vaccinees (HPVfollowup)

Human Papillomavirus Virus

United Kingdom
Public Health England

Completed

A Study to Assess the Impact of Pneumococcal Conjugate Vaccination Programme on the Carriage of Pneumococci (Pneucast)

Pneumococcal Disease

United Kingdom
Public Health England

Completed

A Phase IV Study to Evaluate the Immunogenicity and Safety in UK Laboratory Workers of Menitorix

Vaccination

United Kingdom
Public Health England

Completed

Pertussis and Meningitis C Concomitant Vaccination in Adolescents (Mutliboost)

Pertussis | Meningitis | Immunization | Preventive Immunization; Meningitis

United Kingdom
Public Health England

Completed

Meningococcal B Vaccination in University Students (MNB3)

Neisseria Meningitidis Serogroup B

United Kingdom
Public Health England

Completed

Immunogenicity and Reactogenicity of a Meningococcal B Outer Membrane Vesicle Vaccine Given in a 0,6,12 Month Schedule to Health UK Adults

Neisseria Meningitidis
Public Health England

Completed

The Immediate and Longterm Immune Responses of UK Infants and Young Children to a Booster Dose of Hib Vaccine

Haemophilus Influenzae Type b
Public Health England

Unknown

Improving the Detection of Active Tuberculosis in Accident and Emergency Departments (ACE)

Latent Tuberculosis | Active Tuberculosis

United Kingdom
Public Health England
Bavarian Nordic

Completed

Cohort Study of Healthcare Workers Receiving Imvanex®

Monkeypox

United Kingdom
Nabi Biopharmaceuticals
Public Health England

Completed

StaphVAX Immunogenicity and Safety in Orthopaedic Joint Surgery

Staphylococcal Infections

United Kingdom
St Stephens Aids Trust
Public Health England; NHS England

Unknown

PrEP Impact Trial: A Pragmatic Health Technology Assessment of PrEP and Implementation

HIV Infections
Imperial College London
Public Health England

Recruiting

Screening for HPV and Cervical Cancer in Young Women With Perinatally Acquired HIV (SHiP)

HIV Infections | Cervical Cancer | Human Papillomavirus Infection

United Kingdom
Imperial College London
Public Health England

Completed

Assessment of Viral Shedding Week Following Administration of Live Attenuated Influenza Vaccine in Children (FluSHED-2)

Influenza Vaccines

United Kingdom
University College, London
Public Health England

Completed

COG-UK Project Hospital-Onset COVID-19 Infections Study (COG-UK HOCI)

Coronavirus Infection | Covid-19 | SARS-CoV 2 | Coronavirus | Nosocomial Infection

United Kingdom
University College, London
Public Health England

Completed

Specific Respiratory Infections as Triggers of Acute Medical Events

Cardiovascular Diseases | Influenza, Human | Respiratory Syncytial Virus Infections | Adenovirus | Rhinovirus | Parainfluenza | Human Metapneumovirus Pneumonia

United Kingdom
University College, London
Public Health England

Completed

Predictive Values of Next Generation Interferon Gamma Release Assays for Latent Tuberculosis Infection (NextGen)

Tuberculosis

United Kingdom
Imperial College London
Public Health England

Completed

Efficacy & Safety of Nasal Influenza Immunisation in Children (SNIFFLE-3)

Influenza Vaccines Efficacy and Safety

United Kingdom
Prof. Elizabeth Miller

Completed

Evaluating Vaccine Responses in Healthy Infants Receiving Their Routine Primary Immunisation According to the Accelerated United Kingdom Schedule at 2, 3 and 4 Months (P13UK)

Streptococcus Pneumoniae

United Kingdom
Public Health England
Institute of Child Health

Completed

A Phase III/IV Open-label Study of the Immunogenicity and Safety of a Single Dose of a Live Attenuated Influenza Vaccine (LAIV) (FluenzTM) for Each of Three Successive Years in Children naïve to, or in Previous Receipt of the AS03B Adjuvanted H1N1 (2009) Influenza Vaccine (Pandemrix ™). (LAIV Immuno)

Live Attenuated Influenza Vaccine

United Kingdom
University of Warwick
Public Health England

Enrolling by invitation

Patient Outcomes From Second Film-readers and Test Threshold Relaxation in Breast Screening (POSTBOx)

Breast Cancer | Ductal Carcinoma in Situ

United Kingdom
University of Nottingham
Public Health England

Completed

Flu and Mood in Older Adults (For-ME)

Infection | Vaccination

United Kingdom
Imperial College London
Public Health England

Completed

Safety of Nasal Influenza Immunisation in Children With Asthma (SNIFFLE-4)

Asthma
Public Health England
National Health Service, United Kingdom

Completed

Childhood Influenza Immunisation in General Practice Invitation Trial

Influenza, Human
Public Health England
Department of Health, United Kingdom; Institute of Child Health, London, England

Completed

Hepatitis B Vaccination in Infants (Infanrix)

Pneumococcal Disease | Meningococcal Disease | Diphtheria, Tetanus and Pertussis | Haemophilus Influenzae Serotype b Disease | Hepatitis b

United Kingdom
Prof. Elizabeth Miller
Novartis Vaccines

Completed

Study of Meningococcal B Vaccine and ACWY Conjugate Vaccine in Healthy Adults (MenOccy)

Meningococcal Meningitis, Serogroup A | Meningococcal Meningitis, Serogroup B | Meningococcal Meningitis, Serogroup C | Meningococcal Meningitis, Serogroup Y | Meningococcal Meningitis, Serogroup W

United Kingdom
St George's, University of London
Public Health England

Recruiting

Propositive (Protecting Positive People From Meningococcal Infection) Follow-up Study

HIV/AIDS | Meningococcal Disease

United Kingdom
University Hospitals, Leicester
Public Health England; Novartis Vaccines

Completed

Safety and Immunogenicity of A/H1N1v Vaccines in Healthy Adults

Influenza

United Kingdom
Public Health England
Cardiff University; Aneurin Bevan University Health Board

Unknown

Validation of Molecular and Protein Biomarkers in Sepsis (VAMp-sepsis)

Pneumonia | Sepsis | Cardiac Arrest | SIRS | Abdominal Sepsis

United Kingdom
The Behavioural Insights Team
Public Health England; Department of Health and Social Care; NHS England and...

Completed

Using Text Messages to Boost COVID-19 Vaccine Booking Rate

COVID-19 | Vaccination Hesitancy

United Kingdom
Public Health England
Imperial College London; Institute of Child Health

Withdrawn

Assessment of Novel Pneumococcal Conjugate Vaccination Scheduled in UK Infants (PINC)

Vaccination | Immunization

United Kingdom
Institute of Cancer Research, United Kingdom
Public Health England

Active, not recruiting

Transcriptional Responses as an Indicator of Individualised Responses to Radiation Effects (RTGene 2)

Cancer

United Kingdom
University of Oxford
Imperial College London; Public Health England

Unknown

Genetic Susceptibility to Severe Streptococcal Infections

Invasive Streptococcal Infection | Invasive Group A Streptococcal Disease | Invasive Group B Streptococcal Disease | Necrotising Fasciitis

United Kingdom

Clinical Trials Sponsored by Public Health England (PHE)

Sponsors and Collaborators

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