Clinical Trials Sponsored by Quotient Bioresearch

Total 139 results

Pulmatrix Inc.
Quotient Bioresearch

Completed

Safety, Tolerability, and Pharmacodynamic Effect Study of PUR118

Chronic Obstructive Pulmonary Disease

United Kingdom
Laboratorio Farmaceutico Ct S.r.l.
Latis S.r.l.; Quotient Bioresearch; Voisin Consulting, Inc.

Completed

Safety and Pharmacodynamic Study of GET 73 in Alcohol Dependent (SPAD)

Alcohol Dependence

United States
Praxis Bioresearch, LLC

Completed

Microdose Pharmacokinetic Study of PRX-P4-003 In Healthy Volunteers

Healthy Volunteers

United States
Bridge BioResearch Ltd.

Unknown

Oral BBR-012 in the Treatment of Diabetic Foot Ulcers, Proof of Concept Study (BBR-012)

Diabetic Foot Ulcer

United Kingdom
Asklepios proresearch

Completed

Long-Standing Persistant Atrial Fibrillation-Pulmonary Vein Isolation With or Without Ablation (Alster-Lost)

Atrial Fibrillation | Tachycardia

Germany
Norgine
Quotient Sciences

Completed

A Pharmacokinetic Study of PLENVU® in Healthy Subjects (PKPU)

Pharmacokinetic

United Kingdom
AstraZeneca
Quotient Sciences

Completed

A Randomised, Open-Label Study to Evaluate the Relative and Absolute Bioavailability of Cotadutide in Healthy Subjects

Chronic Kidney Disease | Type 2 Diabetes Mellitus (T2DM) | Non-alcoholic Steatohepatitis

United Kingdom
AstraZeneca
Quotient Sciences

Completed

A Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]AZD9833

ER-positive, HER2-negative Breast Cancer

United Kingdom
AstraZeneca
Quotient Sciences

Completed

AZD4635 Relative Bioavailability Study (Rel Bio)

Healthy Volunteers

United Kingdom
Estetra
Quotient Clinical

Completed

Study Conducted to Further Understand the Elimination Pathways, Metabolite Profile and PK Profile of 14C-estetrol

Menopause | Contraception

United Kingdom
Enterome
Quotient Clinical

Completed

First-in-Human Single and Multiple Dose of EB8018

Healthy Volunteers

United Kingdom
Quotient Diagnostics Limited

Terminated

Reproducibility and Method Comparison Studies of the Quo-Test™ A1C System and the Quo-Lab A1C Test and CLIA Waiver Study of the Quo-Test™ A1C System

Diabetes

United States
AstraZeneca
Quotient Sciences

Completed

A Study to Investigate the Absolute Bioavailability, Absorption, Metabolism, Distribution and Excretion of [14C]AZD5363 (Capivasertib)

Healthy Volunteer

United Kingdom
GlaxoSmithKline
Quotient Clinical

Completed

A Study to Compare the Pharmacokinetics (PK) of GSK2982772 Following Administration of Different Modified Release (MR) Formulations in Capsule and MR Tablet Formulations Relative to an Immediate Release (IR) Tablet Formulation and to Check the PK of MR Formulation in Capsule Following Repeat Doses

Autoimmune Diseases

United Kingdom
AstraZeneca
Quotient Sciences

Completed

A Study to Assess the Rel Bioavailability, Food Effect and Absolute Bioavailability on the Pharmacokinetics of AZD9833

Healthy Volunteers

United Kingdom
GlaxoSmithKline
Quotient Sciences

Completed

A Study to Investigate the Pharmacokinetics (PK) of Modified Release (MR) Prototype Coated Tablet Formulations of GSK2982772

Autoimmune Diseases

United Kingdom
3M
Quotient Clinical

Completed

Cross-over Study in Volunteers to Compare the Pharmacokinetics of Tiotropium Delivered From Test and Reference Products

Healthy

United Kingdom
Asklepios proresearch

Terminated

Alster Stem Cells - Intramyocardial Stem Therapy

Acute Myocardial Infarction | Early Left Ventricular Dysfunction

Germany
AstraZeneca
Quotient Sciences

Active, not recruiting

An ADME Study of [14C]AZD4604 and the Absolute Bioavailability of AZD4604

Asthma

United Kingdom
AstraZeneca
Quotient Sciences

Completed

An ADME Study of [14C]AZD0780 in Healthy Male Subjects

Cardiovascular Diseases

United Kingdom
Bayer
Quotient Sciences

Completed

Mass Balance Study of [14C]-NT-814 Oral Suspension in Healthy Male Subjects

Healthy

United Kingdom
AstraZeneca
Quotient Sciences

Completed

Absolute Bioavailability and ADME Study of [14C]AZD9977 in Healthy Male Subjects

Cardiovascular Disease

United Kingdom
AstraZeneca
Quotient Sciences

Completed

Absolute Bioavailability and ADME Study of Savolitinib in Healthy Male Subjects

Cancer

United Kingdom
AstraZeneca
Quotient Sciences

Completed

A Study to Assess the Mass Balance Recovery, Pharmacokinetics, Metabolite Profile and Metabolite Identification of [14C]AZD4831

Cardiovascular Disease

United Kingdom
AstraZeneca
Quotient Sciences

Completed

Mass Balance Recovery, Pharmacokinetics and Metabolite Profile and Identification of [14C]AZD7594

Asthma

United Kingdom
AstraZeneca
Quotient Sciences

Completed

Study Evaluating the Pharmacokinetic and Mass Balance of Single Dose [14C] AZD5718 in Volunteers

Cardiovascular Disease

United Kingdom
Estetra
Quotient Sciences

Completed

Estetrol (E4)/Drospirenone (DRSP) Drug-drug Interaction (DDI) Study

Contraception

United Kingdom
3M
Quotient Clinical

Completed

Comparison of the Pharmacokinetics of Tiotropium Delivered From Test Inhaler Products With Two Reference Products

Healthy

United Kingdom
Biosearch S.A.

Recruiting

Effect of Consuming a Mixture of Extracts and DHA on the Mild Cognitive Impairment

Mild Cognitive Impairment

Spain
Biosearch S.A.

Unknown

Effect of Consuming a Combination of Probiotic Strains and a Combination of Plant Extracts and a Probiotic Strain on the Production and Nutritional Composition of Breast Milk

Breast Milk Expression

Spain
Biosearch S.A.

Unknown

Evaluation of a Combination of Plant Extracts (BSL_EP028) on Joint Mobility

Joint Diseases

Spain
Biosearch S.A.

Completed

Evaluation of the Effect of a Combination of Plant Extracts (BSL_EP027) on the Incidence of Respiratory Infections

Immune Response | Respiratory Diseases

Spain
Biosearch S.A.

Completed

Evaluation of the Mixture Myoinositol:D-chiro-inositol 3.6:1 in Women With Polycystic Ovary Syndrome

Infertility | Polycystic Ovarian Syndrome
Biosearch S.A.

Completed

Evaluation of Lactobacillus Fermentum CECT5716 on the Incidence of Mastitis

Mastitis

Spain
Biosearch S.A.

Active, not recruiting

Effect of the Consumption of a Lactobacillus Strain on the Incidence of Covid-19 in the Elderly

Elderly | SARS CoV-2 Infection

Spain
Biosearch S.A.

Unknown

Effect of a Lactobacillus Strain on the Prevention of Recurrent Vaginal Candidiasis

Recurrent Vulvovaginal Candidiasis

Spain
Biosearch S.A.

Unknown

Evaluation of a Combination of a Plant Extract and a Probiotic on Glucidic Metabolism in Women With PCOS and High Insulin Levels

Insulin Resistance | Polycystic Ovarian Syndrome

Spain
Biosearch S.A.

Completed

Effect of the Combination of Plant Extracts (BSL_EP025) in Cardiovascular Health

Cardiovascular Disease

Spain
Biosearch S.A.

Recruiting

Effect of Probiotics Consumed During Pregnancy on the Incidence of Mastitis

Women's Health | Lactation | Mastitis | Breast Milk | Infant Health

Spain
Biosearch S.A.

Unknown

Evaluation of the Probiotic Lactobacillus Coryniformis K8 on COVID-19 Prevention in Healthcare Workers

Covid-19

Spain
Biosearch S.A.

Completed

Effect of a Combination of Plant Extracts (BSL_EP024) on the Immune Response

Immune Response

Spain
Biosearch S.A.

Completed

Evaluation of a Probiotic on LDL-cholesterol Levels

Cardiovascular Diseases | LDL-cholesterol

Spain
Biosearch S.A.

Completed

Effects of Lactobacillus Coryniformis CECT5711 on Immune Response to Influenza Vaccination in Adults Over 65.

Immune Response | Probiotics | Influenza Vaccination
NeuroDerm Ltd.
Quotient Clinical

Completed

A Single Period Investigation to Assess the Tolerability of Healthy Subjects to Oral Sinemet® (Levodopa/Carbidopa)

Parkinson's Disease
Genentech, Inc.
Quotient Clinical

Completed

Bioavailability of GDC-0134 and the Effect of Food and Proton Pump Inhibitor on Pharmacokinetics of GDC-0134 in Healthy Female Participants

Amyotrophic Lateral Sclerosis

United Kingdom
Alzheon Inc.
Quotient Clinical

Completed

Single Dose Study of ALZ-801 Prototype Tablets

Alzheimer Disease
EtectRX, Inc.
Quotient Sciences

Completed

Performance of the ID-Cap System, an Ingestion Event Marker, in the Clinical Setting as an Aid to Measure Medication Adherence

Healthy Volunteers

United States
Alzheon Inc.
Quotient Clinical

Completed

Multiple Ascending Dose Study of ALZ-801

Alzheimer Disease

United Kingdom
Celtaxsys, Inc.
Quotient Sciences

Completed

Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-Acebilustat (CTX-4430)

Heathy Volunteers

United Kingdom
GlycoMimetics Incorporated
Quotient Sciences

Completed

A Study in Healthy Volunteers to Investigate How Much Test Medicine [14C]-Uproleselan is Taken up by the Body When Administered Directly Into the Vein (IV)

Healthy Subjects

United Kingdom

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