Clinical Trials Sponsored by Quotient Clinical

Total 18978 results

Estetra
Quotient Clinical

Completed

Study Conducted to Further Understand the Elimination Pathways, Metabolite Profile and PK Profile of 14C-estetrol

Menopause | Contraception

United Kingdom
Enterome
Quotient Clinical

Completed

First-in-Human Single and Multiple Dose of EB8018

Healthy Volunteers

United Kingdom
GlaxoSmithKline
Quotient Clinical

Completed

A Study to Compare the Pharmacokinetics (PK) of GSK2982772 Following Administration of Different Modified Release (MR) Formulations in Capsule and MR Tablet Formulations Relative to an Immediate Release (IR) Tablet Formulation and to Check the PK of MR Formulation in Capsule Following Repeat Doses

Autoimmune Diseases

United Kingdom
3M
Quotient Clinical

Completed

Cross-over Study in Volunteers to Compare the Pharmacokinetics of Tiotropium Delivered From Test and Reference Products

Healthy

United Kingdom
3M
Quotient Clinical

Completed

Comparison of the Pharmacokinetics of Tiotropium Delivered From Test Inhaler Products With Two Reference Products

Healthy

United Kingdom
NeuroDerm Ltd.
Quotient Clinical

Completed

A Single Period Investigation to Assess the Tolerability of Healthy Subjects to Oral Sinemet® (Levodopa/Carbidopa)

Parkinson's Disease
Genentech, Inc.
Quotient Clinical

Completed

Bioavailability of GDC-0134 and the Effect of Food and Proton Pump Inhibitor on Pharmacokinetics of GDC-0134 in Healthy Female Participants

Amyotrophic Lateral Sclerosis

United Kingdom
Alzheon Inc.
Quotient Clinical

Completed

Single Dose Study of ALZ-801 Prototype Tablets

Alzheimer Disease
Alzheon Inc.
Quotient Clinical

Completed

Multiple Ascending Dose Study of ALZ-801

Alzheimer Disease

United Kingdom
Pulmatrix Inc.
Quotient Clinical

Completed

A Safety, Pharmacokinetic and Pharmacodynamic Study of PUR0200 in COPD Patients

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
NeuroDerm Ltd.
Quotient Clinical

Completed

A Sequential Two-Part, Open-Label Study in Healthy Male and Female Subjects

Parkinson's Disease

United Kingdom
Heptares Therapeutics Limited
Quotient Clinical

Completed

Relative Bioavailability Study in Healthy Subjects to Evaluate the Pharmacokinetics of HTL0009936 After One Dose of Prototype Formulation

Alzheimer's Disease

United Kingdom
TauRx Therapeutics Ltd
Quotient Clinical

Completed

Multiple Dose Study of TRx0037

Alzheimer's Disease
TauRx Therapeutics Ltd
Quotient Clinical

Completed

Comparative Bioavailability in Healthy Elderly Volunteers

Alzheimer's Disease
HUYABIO International, LLC.
Quotient Clinical

Completed

A Phase 1 Study of HBI-3000

Atrial Fibrillation

United Kingdom
Oxford Pharmascience Ltd
Quotient Clinical

Completed

Pilot Study of OXP001(2) and Brufen in Healthy Subjects

Gastroduodenal Erosions

United Kingdom
Kadmon Corporation, LLC
Quotient Clinical

Completed

Bioavailability of Belumosudil (KD025) in Healthy Male Subjects

Bioavailability

United Kingdom
F2G Biotech GmbH
Quotient Clinical

Withdrawn

Radiolabelled IV and Oral Metabolism Study of F901318 (ADME)

Invasive Aspergillosis

United Kingdom
Nabriva Therapeutics AG
Quotient Clinical

Completed

A Study to Assess Mass Balance Recovery, Metabolite Profile and Identification of IV and Oral 14C-BC-3781

Healthy

United Kingdom
F2G Biotech GmbH
Quotient Clinical

Withdrawn

Pharmacokinetics of IV Formulation

Invasive Aspergillosis
MEI Pharma, Inc.
Quotient Clinical

Completed

Assessment of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Various Formulations and Doses of PWT-143

Malignancies

United Kingdom
F2G Biotech GmbH
Quotient Clinical

Completed

Evaluation of Immediate Release Tablet

Invasive Aspergillosis

United Kingdom
Ardea Biosciences, Inc.
Quotient Clinical

Completed

IVIVR Assessing PK Parameters Used to Establish Bioequivalence

Healthy

United Kingdom
Orion Corporation, Orion Pharma
Quotient Clinical

Completed

Impact of Changing the Dosing Regimen on the PK Profile of ODM-203 (KIPEV)

Healthy

United Kingdom
Alan Richardson
Quotient Clinical

Terminated

First in Human Single Ascending Dose Study of MOR107

Safety

United Kingdom
Medicines for Malaria Venture
Quotient Clinical

Completed

Bioavailability Study of Oral OZ439 Prototype Granule Formulations Administered With Piperaquine Phosphate (PQP) Tablets

Malaria

United Kingdom
Aquinox Pharmaceuticals (Canada) Inc.
Quotient Clinical

Completed

Phase 1 Absorption Distribution Metabolism and Excretion of AQX-1125 (ADME)

Healthy Volunteer

United Kingdom
Medicines for Malaria Venture
Quotient Clinical

Completed

Bioavailability Study of Oral OZ439 Prototype Formulations Administered With Piperaquine Phosphate (PQP)

Malaria

United Kingdom
Norgine
Quotient Sciences

Completed

A Pharmacokinetic Study of PLENVU® in Healthy Subjects (PKPU)

Pharmacokinetic

United Kingdom
AstraZeneca
Quotient Sciences

Completed

A Randomised, Open-Label Study to Evaluate the Relative and Absolute Bioavailability of Cotadutide in Healthy Subjects

Chronic Kidney Disease | Type 2 Diabetes Mellitus (T2DM) | Non-alcoholic Steatohepatitis

United Kingdom
AstraZeneca
Quotient Sciences

Completed

A Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]AZD9833

ER-positive, HER2-negative Breast Cancer

United Kingdom
AstraZeneca
Quotient Sciences

Completed

AZD4635 Relative Bioavailability Study (Rel Bio)

Healthy Volunteers

United Kingdom
Quotient Diagnostics Limited

Terminated

Reproducibility and Method Comparison Studies of the Quo-Test™ A1C System and the Quo-Lab A1C Test and CLIA Waiver Study of the Quo-Test™ A1C System

Diabetes

United States
AstraZeneca
Quotient Sciences

Completed

A Study to Investigate the Absolute Bioavailability, Absorption, Metabolism, Distribution and Excretion of [14C]AZD5363 (Capivasertib)

Healthy Volunteer

United Kingdom
AstraZeneca
Quotient Sciences

Completed

A Study to Assess the Rel Bioavailability, Food Effect and Absolute Bioavailability on the Pharmacokinetics of AZD9833

Healthy Volunteers

United Kingdom
GlaxoSmithKline
Quotient Sciences

Completed

A Study to Investigate the Pharmacokinetics (PK) of Modified Release (MR) Prototype Coated Tablet Formulations of GSK2982772

Autoimmune Diseases

United Kingdom
AstraZeneca
Quotient Sciences

Active, not recruiting

An ADME Study of [14C]AZD4604 and the Absolute Bioavailability of AZD4604

Asthma

United Kingdom
AstraZeneca
Quotient Sciences

Completed

An ADME Study of [14C]AZD0780 in Healthy Male Subjects

Cardiovascular Diseases

United Kingdom
Bayer
Quotient Sciences

Completed

Mass Balance Study of [14C]-NT-814 Oral Suspension in Healthy Male Subjects

Healthy

United Kingdom
AstraZeneca
Quotient Sciences

Completed

Absolute Bioavailability and ADME Study of [14C]AZD9977 in Healthy Male Subjects

Cardiovascular Disease

United Kingdom
AstraZeneca
Quotient Sciences

Completed

Absolute Bioavailability and ADME Study of Savolitinib in Healthy Male Subjects

Cancer

United Kingdom
AstraZeneca
Quotient Sciences

Completed

A Study to Assess the Mass Balance Recovery, Pharmacokinetics, Metabolite Profile and Metabolite Identification of [14C]AZD4831

Cardiovascular Disease

United Kingdom
AstraZeneca
Quotient Sciences

Completed

Mass Balance Recovery, Pharmacokinetics and Metabolite Profile and Identification of [14C]AZD7594

Asthma

United Kingdom
AstraZeneca
Quotient Sciences

Completed

Study Evaluating the Pharmacokinetic and Mass Balance of Single Dose [14C] AZD5718 in Volunteers

Cardiovascular Disease

United Kingdom
Estetra
Quotient Sciences

Completed

Estetrol (E4)/Drospirenone (DRSP) Drug-drug Interaction (DDI) Study

Contraception

United Kingdom
Pulmatrix Inc.
Quotient Bioresearch

Completed

Safety, Tolerability, and Pharmacodynamic Effect Study of PUR118

Chronic Obstructive Pulmonary Disease

United Kingdom
EtectRX, Inc.
Quotient Sciences

Completed

Performance of the ID-Cap System, an Ingestion Event Marker, in the Clinical Setting as an Aid to Measure Medication Adherence

Healthy Volunteers

United States
Celtaxsys, Inc.
Quotient Sciences

Completed

Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-Acebilustat (CTX-4430)

Heathy Volunteers

United Kingdom
GlycoMimetics Incorporated
Quotient Sciences

Completed

A Study in Healthy Volunteers to Investigate How Much Test Medicine [14C]-Uproleselan is Taken up by the Body When Administered Directly Into the Vein (IV)

Healthy Subjects

United Kingdom
Exscientia Limited
Quotient Sciences

Completed

3-part Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of EXS21546

Oncology

United Kingdom

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