Clinical Trials Sponsored by RTOG Foundation, Inc.

Total 1002 results

RTOG Foundation, Inc.
NovoCure Ltd.

Terminated

Optune® Plus Bevacizumab in Bevacizumab-Refractory Recurrent Glioblastoma

Glioma | Glioblastoma | Gliosarcoma

United States
RTOG Foundation, Inc.
Bristol-Myers Squibb

Terminated

Cisplatin and Etoposide Plus Radiation Followed By Nivolumab/Placebo For Locally Advanced NSCLC

Non-Small Cell Lung Cancer

United States
RTOG Foundation, Inc.
Bristol-Myers Squibb

Completed

Safety Testing of Adding Nivolumab to Chemotherapy in Patients With Intermediate and High-Risk Local-Regionally Advanced Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma (HNSCC)

United States
RTOG Foundation, Inc.
Pfizer; Astellas Pharma Inc

Active, not recruiting

A Study of Salvage Radiotherapy With or Without Enzalutamide in Recurrent Prostate Cancer Following Surgery (STEEL)

Prostate Cancer

United States, Canada
RTOG Foundation, Inc.
Merck Sharp & Dohme LLC

Recruiting

SBRT +/- Pembrolizumab in Patients With Local-Regionally Recurrent or Second Primary Head and Neck Carcinoma (KEYSTROKE)

Head and Neck Squamous Cell Carcinoma (HNSCC)

Canada, United States
Novartis Pharmaceuticals
Alliance Foundation Trials, LLC.; RTOG Foundation, Inc.

Active, not recruiting

An International Prospective Open-label, Randomized, Phase III Study Comparing 177Lu-PSMA-617 in Combination With SoC, Versus SoC Alone, in Adult Male Patients With mHSPC (PSMAddition)

Prostatic Neoplasms

United States, China, Canada, Spain, United Kingdom, Belgium, Japan, Taiwan, Germany, Singapore, Austria, Netherlands, Korea, Republic of, France, Switzerland, Denmark, Sweden, Poland, Czechia
American College of Radiology
RTOG Foundation

Not yet recruiting

Testing the Safety of Giving a Standard Dose of Radiation Over a Shorter Period of Time for Patients Who Had Surgery for Intermediate-Risk Head and Neck Cancer

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Squamous Cell Carcinoma of the Larynx | Squamous Cell Carcinoma of the Oral Cavity | Squamous Cell Carcinoma of the Oropharynx
NSABP Foundation Inc

Completed

Study of Durvalumab (MEDI4736) After Chemo-Radiation for Microsatellite Stable Stage II-IV Rectal Cancer

Rectal Cancer

United States
NSABP Foundation Inc

Withdrawn

Safety and Efficacy Study of Neratinib and Cetuximab to Treat Patients With Quadruple Wild-Type Metastatic Colorectal Cancer

Colorectal Cancer

United States
NSABP Foundation Inc

Completed

A Study of Gemcitabine, Epirubicin, and Paclitaxel Combination Chemotherapy Given Before Surgery to Patients With Locally Advanced Breast Cancer

Breast Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIB Breast Cancer | Locally Advanced

United States
NSABP Foundation Inc

Completed

NSABP Patient Registry and Biospecimen Profiling Repository

Colorectal Cancer

United States
CHDI Foundation, Inc.

Recruiting

Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

Huntington's Disease

United States, Canada, Belgium, Spain, Australia, Germany, France, Netherlands, United Kingdom, New Zealand, Argentina, Austria, Chile, Colombia, Denmark, Ireland, Italy, Poland, Portugal, Switzerland
NSABP Foundation Inc

Completed

Study of Durvalumab and Tremelimumab After Radiation for Microsatellite Stable Metastatic Colorectal Cancer Progressing on Chemotherapy

Colorectal Cancer Metastatic

United States
CHDI Foundation, Inc.

Unknown

Development of Assessments for Later Stage HD (LSA)

Huntington Disease

United States, United Kingdom
CHDI Foundation, Inc.

Completed

Follow-up Measurement of Brain PDE10A Enzyme Levels in Huntington´s Disease Gene Expansion Carriers (LONGPDE10)

Huntington's Disease

Sweden, Denmark, Netherlands, Norway
CHDI Foundation, Inc.

Completed

[PETDE10] Imaging of PDE10A Enzyme Levels in Huntington's Disease Gene Expansion Carriers and Healthy Controls With PET. (PEARL-HD)

Huntington's Disease

Sweden, Denmark, Netherlands, Norway
CHDI Foundation, Inc.
Medpace, Inc.

Active, not recruiting

Natural History Study in Huntington Disease Gene Expansion Carriers (HDGECs) - SHIELD HD (SHIELD HD)

Huntington Disease

United States, Canada, France, Germany, United Kingdom
NSABP Foundation Inc
Eisai Inc.

Completed

Comparison of Neoadjuvant Chemotherapy With Weekly Paclitaxel or Eribulin Followed by A/C in Women With Locally Advanced HER2-Negative Breast Cancer

Breast Cancer | HER2-negative Breast Cancer

United States, Canada
NSABP Foundation Inc
Puma Biotechnology, Inc.

Completed

A Dose-Escalation Study Evaluating the Combination of Trastuzumab Emtansine (T-DM1) With Neratinib in Women With Metastatic HER2-Positive Breast Cancer

Breast Cancer

United States
NSABP Foundation Inc
Puma Biotechnology, Inc.

Active, not recruiting

Study of Neratinib +Trastuzumab or Neratinib + Cetuximab in Patients With KRAS/NRAS/BRAF/PIK3CA Wild-Type Metastatic Colorectal Cancer by HER2 Status

Metastatic Colorectal Cancer

United States
Life Extension Foundation Inc.

Completed

Efficacy and Safety Study of Propofol Infusion for Refractory Chronic Primary Insomnia

Sleep Disorder | Insomnia | Dyssomnia

United States
GlaxoSmithKline
NSABP Foundation Inc

Completed

Treatment With Pazopanib for Neoadjuvant Breast Cancer

Neoplasms, Breast

United States, Canada
Kessler Foundation
Saebo, Inc.

Completed

Saeboflex Dynamic Hand Orthosis for Inpatient Rehabilitation Stroke Patients

Stroke

United States
COPD Foundation
Viatris Inc.

Recruiting

Impairments That Affect Correct Inhaler Use in COPD (INHALE)

COPD

United States
Agenus Inc.
GOG Foundation

Active, not recruiting

RaPiDS- A Phase 2 Study of Anti-PD-1 Independently or in Combination With Anti-CTLA-4 in Second-Line Cervical Cancer

Cervical Cancer

United States, Korea, Republic of, Taiwan, Brazil, Mexico, Peru, Thailand
NSABP Foundation Inc
Bayer

Terminated

A Study Evaluating Regorafenib Following Completion of Standard Chemotherapy for Patients With Colon Cancer (ARGO)

Stage III (IIIB or IIIC) Colon Cancer

United States
Stern Cardiovascular Foundation, Inc.

Terminated

Implementation of a Protocol Utilizing Adaptive CRT in a Normal AV Conduction, CRT Non-Response Population at Generator Replacement

Heart Failure

United States
Foundation Medicine
Quintiles, Inc.

Completed

FoundationOne™ Test Registry Study (FMI Registry)

Cancer | Neoplasm Metastasis | Tumor

United States
Life Extension Foundation Inc.

Completed

Short Term Efficacy and Safety of Perispinal Administration of Etanercept in Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

United States
Neurologique Foundation, Inc.
Mallinckrodt

Terminated

Efficacy Study of Adrenocorticotropin Hormone to Treat Multiple Sclerosis (MS) Relapses After Sub-responding to an Initial 3 Day Course of Intravenous (IV) Methylprednisolone (RECLAIM)

Multiple Sclerosis

United States
NSABP Foundation Inc
Sanofi

Withdrawn

Safety and Effectiveness Study of Chemotherapy and Ziv-aflibercept to Treat Metastatic Colorectal Cancer

Metastatic Colorectal Cancer | Colorectal Cancer
NSABP Foundation Inc
Amgen

Withdrawn

Study of Panitumumab Given First With Capecitabine and Oxaliplatin (CAPOX) and Then With Capecitabine and Radiation of the Pelvis for Treatment of Patients With Rectal Cancers That May or May Not Have Spread Beyond the Rectum

Neoplasm Metastasis | Rectal Cancer
NSABP Foundation Inc
AstraZeneca

Completed

Therapy With Docetaxel and ZD1839 for Patients Who Have Advanced Breast Cancer

Breast Neoplasms

United States
ETOP IBCSG Partners Foundation
NSABP Foundation Inc

Completed

Adjuvant Chemotherapy in Treating Women Who Have Undergone Resection for Relapsed Breast Cancer; Chemotherapy as Adjuvant for LOcally Recurrent Breast Cancer (CALOR)

Breast Cancer

Spain, United States, Australia, Belgium, Switzerland, Canada, Peru, Netherlands, Hungary, South Africa
NSABP Foundation Inc
Puma Biotechnology, Inc.

Completed

Phase II Randomized Trial Evaluating Neoadjuvant Therapy With Neratinib and/or Trastuzumab Followed by Postoperative Trastuzumab in Women With Locally Advanced HER2-positive Breast Cancer

Breast Cancer

United States, Canada, Puerto Rico, Italy, Spain
ImmunoGen, Inc.
GOG Foundation

Recruiting

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Ovarian, Fallopian Tube, or Peritoneal Cancer (GLORIOSA)

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer

United States, Korea, Republic of, Spain, Australia, Canada, United Kingdom, Italy, Belgium, Czechia, Philippines, Israel
Target ALS Foundation, Inc.

Recruiting

Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures (TALSLB)

Movement Disorders | Motor Neuron Disease | Amyotrophic Lateral Sclerosis | Degenerative Disorder

United States
NSABP Foundation Inc
GlaxoSmithKline

Unknown

A Study of AC Followed by a Combination of Paclitaxel Plus Trastuzumab or Lapatinib or Both Given Before Surgery to Patients With Operable HER2 Positive Invasive Breast Cancer

Invasive Breast Cancer

United States, Canada, Puerto Rico
NSABP Foundation Inc
Pfizer

Completed

Combination of Weekly Paclitaxel With Neratinib and Trastuzumab in Women With Metastatic HER2-positive Breast Cancer

Breast Cancer

United States
Kessler Foundation
Saebo, Inc.

Completed

A Pilot Study Investigating the Feasibility of the Saebo Arm Training Program on an Inpatient Population

Stroke | Hemiplegia

United States
Genentech, Inc.
Flatiron Health, Inc.; Foundation Medicine, Inc.

Completed

Prospective Clinicogenomic Program (PCG)

Non-Small Cell Lung Cancer (NSCLC) | Small-Cell Lung Cancer (SCLC)

United States
NSABP Foundation Inc
Novartis Pharmaceuticals; Natera, Inc.

Withdrawn

A Single Arm Phase II Study to Evaluate Treatment With Gevokizumab in Patients With Stage II/III Colon Cancer Who Are ctDNA-positive After Curative Surgery and Adjuvant Chemotherapy

Colon Cancer

United States
Mylan Inc.
Cystic Fibrosis Foundation

Completed

Observational Study in Cystic Fibrosis Patients Using TOBI® PODHALER® or Other FDA Approved Inhaled Antipseudomonal Antibacterial Drugs

Pseudomonas Aeruginosa in Cystic Fibrosis

United States
Savara Inc.
Cystic Fibrosis Foundation; Synteract, Inc.

Completed

Efficacy and Safety Study of AeroVanc for the Treatment of Persistent MRSA Lung Infection in Cystic Fibrosis Patients

Cystic Fibrosis

United States
Research Foundation for Mental Hygiene, Inc.
FDC Foundation

Completed

Disulfiram: A Test of Symptom Reduction Among Patients With Previously Treated Lyme Disease

Quality of Life | Fatigue

United States
NSABP Foundation Inc
Genentech, Inc.; Celcuity, LLC

Recruiting

Study of Neoadjuvant Chemotherapy Plus Trastuzumab and Pertuzumab in HER2-Negative Breast Cancer Patients With Abnormal HER2 Signaling (FB-12)

HER2-negative Breast Cancer

United States
Public Health Foundation Enterprises, Inc.

Recruiting

mHealth Systems Navigation- Breaking Systems Barriers for Trans Women Living With HIV (mSN)

Substance Use | Mental Health Issue

United States
CHDI Foundation, Inc.
IQVIA Company

Completed

HD-Charge: Indirect and Out-of-Pocket Costs of Huntington's Disease in the United States

Huntington's Disease

United States
The Hawkins Foundation
BREG, Inc

Completed

Effectiveness of BREG Flex in 12-week Peri-operative Total Knee Arthroplasty

Knee Osteoarthritis

United States
FUSMobile Inc.
Focused Ultrasound Foundation

Completed

Safety and Initial Feasibility of Using the Neurolyser for Facet Related Low Back Pain

Facet Related Low Back Pain

Canada

Clinical Trials Sponsored by RTOG Foundation, Inc.

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