Clinical Trials Sponsored by Renalis

Total 212 results

Renovis

Unknown

Dose-Finding Study of REN-1654 in Patients With Post-Herpetic Neuralgia

Neuralgia | Peripheral Nervous System Disease | Shingles

United States
Renovis

Unknown

Study of REN-1654 in Patients With Sciatica Pain

Sciatica | Radiculopathy | Herniated Disc

United States
Renatus, Antonio Renatus, Dent., M.Sc

Completed

Evaluation of a New Self-reported Tool for Periodontitis Screening

Periodontitis and Treatment Need
Renalis
University Hospitals Cleveland Medical Center

Recruiting

Treatment of Overactive Bladder With a Digital Conversational Agent: the MOTIVATION Study (MOTIVATION)

Overactive Bladder | Pelvic Floor Disorders | Urge Incontinence

United States
Venaxis, Inc.

Completed

The Performance of the APPY1 Test in the Evaluation of Possible Acute Appendicitis (APPY1)

Acute Appendicitis

United States
Tenaxis Medical, Inc.

Completed

A Study to Evaluate the Safety and Performance of ArterX™ Vascular Sealant in Sealing Synthetic Arterial Grafts

Vascular Disease

Germany
Tenaxis Medical, Inc.

Completed

ArterX Safety and Efficacy Study for Cardiac Indications

Vascular Disease

Germany
Tenaxis Medical, Inc.

Completed

ArterX Surgical Sealant, A Randomized Prospective Multicenter Trial (StEPS)

Vascular Disease

United States
St. Renatus, LLC

Completed

Comparison of Anesthetic Efficacy of Bilateral and Unillateral Application of Kovacaine Mist in Healthy Volunteers

Anesthesia

United States
Denali Therapeutics Inc.

Recruiting

A Phase 1, Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-DNL343 Following a Single Oral Dose in Healthy Male Participants

Healthy Volunteers

United States
Denali Therapeutics Inc.

Recruiting

A Study of Tividenofusp Alfa (DNL310) in Pediatric Participants With Hunter Syndrome

Mucopolysaccharidosis II

United States, Netherlands, Canada, United Kingdom
Denali Therapeutics Inc.

Enrolling by invitation

An Extension Study of the Long-Term Safety, Tolerability, and Efficacy of Tividenofusp Alfa (DNL310) in Participants With Mucopolysaccharidosis Type II (MPS II) From Study DNLI-E-0002 or Study DNLI-E-0007

Mucopolysaccharidosis II

United States, Canada, Belgium, Czechia, Netherlands
Denali Therapeutics Inc.

Completed

Study to Evaluate DNL747 in Subjects With Alzheimer's Disease

Alzheimer Disease

United States, Netherlands
Denali Therapeutics Inc.

Recruiting

Study of DNL126 in Pediatric Participants With Mucopolysaccharidosis Type IIIA (Sanfilippo Syndrome Type A)

Mucopolysaccharidosis Type IIIA

United States
Denali Therapeutics Inc.

Completed

A Study of Potential Treatment-Responsive Biomarkers and Clinical Outcomes in Hunter Syndrome

Mucopolysaccharidosis II

United Kingdom, United States, Italy, Netherlands
Denali Therapeutics Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL151 in Healthy Volunteers

Healthy Volunteers

Netherlands
Denali Therapeutics Inc.

Completed

A Study to Evaluate the Bioavailability and Safety of DNL343 in Healthy Volunteers

Healthy Volunteers

New Zealand
Denali Therapeutics Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL201 in Healthy Volunteers

Healthy Volunteers

United States
Renal Research Institute
Renal Solutions, Inc.

Unknown

Comparison of Conventional Dialysis and the Allient System

End Stage Renal Disease | Chronic Kidney Failure

United States
Denali Therapeutics Inc.

Recruiting

A Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) vs Idursulfase in Pediatric Participants With Neuronopathic (nMPS II) or Non-Neuronopathic Mucopolysaccharidosis Type II (nnMPS II) (COMPASS)

Mucopolysaccharidosis II

United States, Spain, United Kingdom, Czechia, France, Canada, Italy, Belgium, Netherlands, Germany, Argentina, Sweden, Turkey, Colombia
Denali Therapeutics Inc.

Active, not recruiting

A Study to Determine the Safety, Pharmacokinetics, and Pharmacodynamics of DNL343 in Participants With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

United States, Netherlands
Denali Therapeutics Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL343 in Healthy Volunteers

Healthy Volunteers

Netherlands
Denali Therapeutics Inc.

Completed

Study to Evaluate DNL201 in Subjects With Parkinson's Disease

Parkinson Disease

United States
Vernalis (R&D) Ltd

Completed

Safety, Tolerability, PK & Efficacy of V81444 in Volunteers With Attention Deficit/ Hyperactivity Disorder (ADHD)

ADHD

United States
Vernalis (R&D) Ltd

Completed

Safety and Efficacy Study in Acute Ischaemic Stroke (VASST)

Stroke

United States, Canada
Vernalis (R&D) Ltd

Completed

A Study in Healthy Male Volunteers to Investigate a New Drug for the Treatment of Parkinson's Disease

Parkinson's Disease
Vernalis (R&D) Ltd

Completed

Study of the Safety, Tolerability and Efficacy of V3381 in Patients With Diabetic Peripheral Neuropathic Pain

Diabetic Peripheral Neuropathic Pain

United States, United Kingdom, Canada, Czech Republic
Renovis Surgical Technologies, Inc.

Active, not recruiting

E-MAX 2nd Gen Vit E Poly On BIOLOX Delta Ceramic Heads

In Need of a Total Hip Arthroplasty

United States
Vernalis (R&D) Ltd

Completed

Single and Multiple Ascending Dose Study of V158866 in Healthy Volunteers

First in Man Study

United Kingdom
Vernalis (R&D) Ltd

Completed

A Clinical Trial to Find Out V81444's Side Effects and Blood Levels in Healthy Men

Parkinson's Disease

United Kingdom
Vernalis (R&D) Ltd

Completed

Safety and Efficacy of Low Doses of V24343 in Obese Subjects

Obesity

United Kingdom
Unidad de Investigacion Medica en Enfermedades...

Completed

The Effect of Enalapril, Losartan or Not Antihypertensive on the Oxidative Status in Renal Transplant Recipients

Oxidative Stress

Mexico
Unidad de Investigacion Medica en Enfermedades...

Completed

ESTEROID WITHDRAWAL STUDY, SAFETY AND EFFICACY IN RENAL TRANPLANTATION (ESWMEX001)

END STAGE RENAL DISEASE

Mexico
Renal Research Institute
Renal Solutions, Inc.

Terminated

Sorbent Treatment Prescriptions Pilot Study (Sorb2)

Renal Failure

United States
Unidad de Investigacion Medica en Enfermedades...

Unknown

Curcumin on NFE2L2 Gene Expression, Antioxidant Capacity and Renal Function According to rs35652124 in Diabetic Nephropathy (CURCUNRF2)

Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Polymorphism

Mexico
Denali Therapeutics Inc.
Takeda

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL919 in Healthy Participants

Healthy Participant

Netherlands
Biogen
Denali Therapeutics Inc.

Completed

A Study to Determine the Absolute Bioavailability of BIIB122/DNL151 in Healthy Subjects

Healthy Volunteers

United States
Biogen
Denali Therapeutics Inc.

Recruiting

A Study to Assess the Safety of BIIB122 Tablets and if it Can Slow the Worsening of Early-Stage Parkinson's Disease in Participants Between the Ages of 30 and 80 (LUMA)

Parkinson Disease

United States, Netherlands, Italy, Spain, Israel, Canada, China, Germany, France, Austria, United Kingdom, Poland, Japan
Biogen
Denali Therapeutics Inc.

Terminated

A Study to Assess if BIIB122 Tablets Are Safe and Can Slow Worsening of Early-Stage Parkinson's Disease in Participants With Specific LRRK2 Genetic Variants Between the Ages of 30 and 80 Using the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (LIGHTHOUSE)

Parkinson Disease

United States, Italy, Spain, Germany, France, United Kingdom
Biogen
Denali Therapeutics Inc.

Completed

A Study of Mass Balance, Pharmacokinetics, Metabolite Profile, and Metabolite Identification of BIIB122/DNL151 in Healthy Male Subjects

Healthy Volunteers

United States
Denali Therapeutics Inc.
Takeda

Active, not recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia (FTD-GRN)

Frontotemporal Dementia

Spain, Turkey, France, Belgium, Netherlands, Portugal, Italy, Colombia, Czechia, Brazil, United Kingdom, Serbia
Sanofi
Denali Therapeutics Inc.

Terminated

Study to Evaluate DNL747 in Subjects With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

United States, Netherlands
Renal Research Institute

Unknown

Identification of Desaturation Episodes by Means of Continuous Measurement of Oxygen Saturation During Hemodialysis

Sleep Apnea | ESRD | Oxygen Deficiency

United States
Renal Research Institute

Terminated

Body Fluid Dynamics in Hemodialysis Patients, an Estimation of Dry Weight

Chronic Kidney Disease
Renal Research Institute

Terminated

Red Blood Cell Lifespan (RBC)

Hemodialysis | Chronic Kidney Disease

United States
Renal Research Institute

Terminated

Comparison of Body Hydration State in Hemodialysis Patients

Hemodialysis | Chronic Kidney Disease

United States
Renal Research Institute

Completed

Hemodialysis Vascular Access Imaging Study

Fistula | Chronic Kidney Disease | Hemodialysis Fistula Thrombosis

United States
Renal Research Institute

Completed

Oxygen Desaturation During Hemodialysis

Hypoxia | Renal Disease

United States
Renal Research Institute

Completed

A Comparison of Physical Activity Levels With and Without Feedback Via Fitbit® Flex™ in Hemodialysis Patients (IAM)

End Stage Renal Disease

United States
Renal Research Institute

Withdrawn

Effects of Intensified Sodium Management in Hemodialysis Patients

Renal Failure Chronic Requiring Hemodialysis

United States

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