Clinical Trials Sponsored by Rottapharm Biotech

Total 1797 results

Rottapharm Biotech

Completed

A Study of the EP4 Antagonist CR6086 in Combination With Methotrexate, in DMARD-naïve Patients With Early Rheumatoid Arthritis

Rheumatoid Arthritis, DMARD-naive and Early Disease Patients

Czechia
Rottapharm Biotech

Completed

Intra-articular PVA Hydrogel in Knee Osteoarthritis

Knee Osteoarthritis

Poland
Takis
Rottapharm Biotech

Terminated

Safety and Immunogenicity of COVID-eVax, a Candidate Plasmid DNA Vaccine for COVID-19, in Healthy Adult Volunteers

COVID-19 | COVID-19 Immunisation | Protection Against COVID-19 and Infections With SARS-CoV- 2

Italy
Rottapharm Biotech
Agenus Inc.

Active, not recruiting

A Phase Ib/IIa Study of CR6086 in Combination With Balstilimab in pMMR-MSS Metastatic Colorectal Cancer Patients

Solid Tumor | Metastatic Microsatellite-stable Colorectal Cancer | Mismatch Repair Protein Proficient | Refractory Metastatic Colorectal Cancer

Italy
Rottapharm

Completed

DARWIN Study: A Randomization/Withdrawal Efficacy Study of Dexloxiglumide in Constipation-Predominant Irritable Bowel Syndrome (C-IBS)

Irritable Bowel Syndrome

United Kingdom
Rottapharm

Completed

Metabolic and Cardiovascular Effects of Armolipid Plus in Subjects With Metabolic Syndrome (ARMP-11)

Metabolic Syndrome | Left Ventricular Hypertrophy | Insulin-resistance

Italy
Rottapharm Spain

Completed

Study to Evaluate the Effect of Megestrol Acetate in Severe Chronic Obstructive Pulmonary Disease With Loss of Weight

Chronic Obstructive Pulmonary Disease

Spain
Rottapharm Spain

Completed

Effect of the Plantago Ovata Husk on the Lipid Profile of Patients With Hypercholesterolemia

Cardiovascular Disease | Hypercholesterolemia

Spain
Rottapharm

Withdrawn

Randomized Study for the Assessment of Silibinin (Legalon® SIL) in the Treatment of naïve Genotype 4 Patients With Chronic Hepatitis C (HEPASIL)

Hepatitis C, Chronic

Egypt
Rottapharm

Unknown

Estromineral Serena Plus and Symptomatic Menopause

Menopause

Italy
Rottapharm

Terminated

Legalon SIL for the Treatment of HCV Recurrence in Liver Transplanted Patients

HCV Recurrence After Liver Transplantation
Rottapharm

Completed

Glucosamine Unum In Die [Once A Day] Efficacy (GUIDE) Trial: Glucosamine Sulfate in Patients With Knee Osteoarthritis

Knee Osteoarthritis

Spain, Portugal
Rottapharm Spain

Completed

Pharmacodynamic-pharmacokinetic Trial, of Slow Release ASA, in the Platelet Functionalism.

Cardiovascular Disease

Spain
Rottapharm Spain

Completed

Study of the Modification of the Pharmacokinetic Profile of Levodopa by the Fiber Plantago Ovata Husk

Parkinson's Disease, Idiopathic

Spain
Rottapharm Spain

Completed

Isoflavones and Magnolia Extract in the Quality of Life in Menopausal Women (ESTROCALVI)

Menopause

Spain
Rottapharm Spain

Terminated

Trial to Evaluate the Effect of Plantago Ovata Husk in the Remission of Metabolic Syndrome in Children and Adolescents

Metabolic Syndrome

Spain
Rottapharm Spain

Terminated

Study to Evaluate the Effect of Megestrol Acetate in Weight Loss in Dementia Patients

Dementia

Spain
Rottapharm Spain

Completed

Pharmacodynamic Trial, of Slow Release ASA, in Platelet Functionalism, a Long Term Treatment Period

Cardiovascular Disease

Spain
University of Malaya
Rottapharm

Completed

Silymarin for the Treatment of Non-Alcoholic Fatty Liver Disease (NAFLD)

Non-alcoholic Fatty Liver Disease

Malaysia
Rottapharm
Federico II University

Completed

Armolipid Plus and Metabolic Syndrome

Metabolic Syndrome

Italy
Federico II University
Rottapharm

Completed

Effects of Armolipid Plus on Cholesterol Levels and Endothelial Function

Endothelial Dysfunction | Hyperlipidemia

Italy
University of Milano Bicocca
Rottapharm

Completed

ElectroPoration In a Clinical Setting (EPIC)

Tolerance

Italy
Rottapharm
Azienda Ospedaliera Universitaria Policlinico

Terminated

Effect of LEGALON SIL on Hepatitis C Virus Recurrence in Stable Liver Transplanted Patients (LEG-SIL-LTX-02)

Hepatitis C Virus Recurrence

Italy
Theratocular Biotek Co.

Recruiting

A Study to Investigate the Effect on Central Macular Thickness of Treatment With MG-O-1002 Eye Drops in Participants Aged Over 45 With Neovascular Age-related Macular Degeneration (nAMD)

Age-Related Macular Degeneration

Thailand
Rottapharm Spain
Centro Tecnológico de Nutrición y Salud

Completed

Combined Effects of Bioactive Compounds in Lipid Profile (ARM-PLUS-LDL)

Hyperlipidemia | Elevated Triglycerides | Low-density-lipoprotein-type

Spain
Sotio Biotech Inc.
SOTIO Biotech AG; SOTIO Biotech a.s.

Recruiting

BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors (DUET-1)

Hepatocellular Carcinoma | Squamous Cell Carcinoma of the Lung | Merkel Cell Carcinoma | Myxoid/Round Cell Liposarcoma

United States
SOTIO Biotech AG
SOTIO Biotech a.s.

Active, not recruiting

Study of SO-C101 and SO-C101 in Combination With Pembro in Adult Patients With Advanced/Metastatic Solid Tumors

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Gastric Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Mesothelioma | Bladder Cancer | Triple Negative Breast Cancer | Small-cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Thyroid | Anal Cancer | Merkel Cell Carcinoma | Biliary... and other conditions

United States, France, Spain, Czechia
Neovii Biotech
Fresenius Biotech North America

Completed

Safety and Efficacy Study of Catumaxomab to Treat Ovarian Cancer After a Complete Response to Chemotherapy

Ovarian Cancer

United States
Neovii Biotech
Fresenius Biotech North America

Terminated

Phase II Study With the Trifunctional Antibody Ertumaxomab to Treat Metastatic Breast Cancer After Progression on Trastuzumab Therapy

Advanced Breast Cancer | Metastatic Breast Cancer

United States, Canada
Impact Biotech Ltd
Impact biotech Ltd.

Not yet recruiting

Padeliporfin VTP Using Robotic Assisted Bronchoscopy in Peripheral Lung Cancer

Peripheral Lung Tumor
J2H Biotech

Recruiting

Phase 2a Study to Evaluate Safety and Explore Efficacy of J2H-1702 for NASH

Non-alcoholic Steatohepatitis

Korea, Republic of
Essen Biotech

Not yet recruiting

Fourth-gen CAR T Cells Targeting CD19/CD22 for Highly Resistant B-cell Lymphoma/Leukemia (PMBCL/CNS-BCL). (BAH241)

Lymphoma, Follicular | Diffuse Large B Cell Lymphoma | Acute Lymphoblastic Leukemia, in Relapse | MCL | Central Nervous System Lymphoma | Acute Lymphoblastic Leukemia, Adult B-Cell | Non-Hodgkin Lymphoma, B-cell

China
Meccellis Biotech

Recruiting

Evaluation of a Non-cross-linked Porcine Acellular Dermal Matrix Used in Dental Surgery

Dental Surgery

France
HoHo Biotech

Recruiting

To Evaluate the Safety of Treating Rheumatologic and Metabolic Patients With Molecular Hydrogen Supplement.

Autoimmune Diseases | Metabolic Disease

Taiwan
Acticor Biotech

Completed

Glenzocimab in SARS-Cov-2 Acute Respiratory DistrEss syNdrome Related to COVID-19 (GARDEN)

COVID-19 | Acute Respiratory Distress Syndrome | ARDS | SARS-CoV Infection

France
Neovii Biotech

Completed

Study of US-ATG-F to Prevent Chronic Graft Versus Host Disease (GVHD)

Myelodysplastic Syndrome | GVHD | Adult Acute Myeloid Leukemia | Adult Acute Lymphoid Leukemia

United States, Australia
Activartis Biotech

Completed

Dendritic Cell Cancer Vaccine for High-grade Glioma (GBM-Vax)

Glioblastoma Multiforme

Austria
Trinity Biotech

Unknown

Clinical Study to Validate the Use of a New Point of Care Troponin I Test

Acute Coronary Syndrome

United States
Oncolytics Biotech

Completed

Phase 2 Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Patients With Head and Neck Carcinoma

Carcinoma, Squamous Cell of the Head and Neck

United States
Oncolytics Biotech

Completed

Safety and Efficacy Study of REOLYSIN® in the Treatment of Recurrent Malignant Gliomas

Malignant Glioma

United States
Neovii Biotech

Completed

Safety Study of Second Intraperitoneal (I.P.) Infusion Cycle of Catumaxomab in Patients With Malignant Ascites (SECIMAS)

Malignant Ascites Due to Epithelial Carcinoma

Germany
Facet Biotech

Withdrawn

A Randomized, Double-blinded, Placebo-controlled, Dose-ranging Study of Cardene® I.V. in Pediatric Subjects With Hypertension

Hypertension

United States
Facet Biotech

Completed

Research Study of Visilizumab for Treatment of Acute Graft Versus Host Disease

Graft vs Host Disease

United States
Facet Biotech

Completed

Research Study in Patients With Severe Ulcerative Colitis

Ulcerative Colitis

United States
Facet Biotech

Withdrawn

A Study of Ularitide in the Treatment of Subjects With Acute Decompensated Heart Failure

Heart Failure, Congestive

United States
Neovii Biotech

Terminated

Phase II Study With the Trifunctional Antibody Ertumaxomab to Treat Metastatic Breast Cancer Progressing After Endocrine Treatment

Advanced Breast Cancer | Metastatic Breast Cancer

Spain, Austria, France, Germany, Italy
Neovii Biotech

Completed

Safety and Efficacy Study With Catumaxomab in Patients After Curative Resection of a Gastric Adenocarcinoma

Gastric Cancer | Gastric Adenocarcinoma

Germany
Global Biotech

Completed

Safety Study of a Recombinant Human Plasminogen Activator to Treat Acute Ischemic Stroke.

Cerebrovascular Accident

Taiwan
Aurion Biotech

Recruiting

A Phase 1/2 Study of AURN001 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction (ABA-1) (CLARA)

Corneal Edema | Corneal Endothelial Dysfunction

United States, Canada
Meccellis Biotech

Recruiting

Safety and Clinical Performance of a Biological Matrix Used in Implant-based Breast Reconstruction

Breast Reconstruction Following Mastectomy

France

Clinical Trials Sponsored by Rottapharm Biotech

Sponsors and Collaborators

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