Clinical Trials Sponsored by SEBASTIAN ROCHE

Total 3066 results

SEBASTIAN ROCHE
Sebastián Roche, MD; Santiago Bertone, MD; Claudio Brandi, MD

Completed

Evaluation of Dexamethasone Added to the Usual Infiltration With Bupivacaine in Inguinal Hernia Repair Mesh

Pain, Postoperative

Argentina
Roby Sebastian

Withdrawn

Changes in Cerebral Oxygenation During Laparoscopy in Patients With Single Ventricle Anatomy

Congenital Heart Disease | Single Ventricle

United States
Universidad San Sebastián

Active, not recruiting

Physical Exercise on Physiological Adaptation Capacity and Chronic Pain in Individuals With Cardiovascular Risk

Cardiometabolic Risk Factors

Chile
Universidad San Sebastián

Unknown

Immediate Effects of the C0-C1 Mobilization Technique in Patients With Chronic Neck Pain

Cervical Pain | Musculoskeletal Manipulations

Chile
Hospital de Sao Sebastiao

Completed

Efficacy Comparative Study Between Tears Again®, Opticol® and Optive®

Dry Eye Syndrome

Portugal
Sebastian Koch

Withdrawn

Remote Ischemic PreConditioning (RIPC)

Unruptured Cerebral Aneurysm

United States
Sebastian Kelle

Completed

Analysis of Cardiac Damage Post Infection With SARS-CoV-2 and Post Vaccination Against COVID-19

Myocarditis Acute

Germany
Sebastian Carballo

Recruiting

Prospective Registry of Acute Heart Failure

Acute Heart Failure

Switzerland
Sebastian Zingler

Completed

Mechanical Plaque Control and Gingivitis Reduction in Fixed Appliance Patients

Gingivitis | Dental Plaque

Germany
Sebastian Videla

Recruiting

Effect and Safety of Listening to Music for Chronic Pain Relief

Chronic Pain

Spain
Stec, Sebastian, MD, PhD, FESC
KCRI

Recruiting

Permanent Pacemaker Implantation or Cardioneuroablation in Sinus Node Dysfunction (SANOK)

Sinus Node Dysfunction

Poland
Dr Sebastian Sundaraj

Completed

Does Strepsils® With Lignocaine Lozenges Reduce Post Operative Sore Throat Due To Supraglottic Airway Devices (POSTrepsils)

Sore Throat | Post Operative Sore Throat

Malaysia
Sebastian Videla

Completed

Investigating the Efficacy and Safety ICATIBANT For The Treatment of Patients With SARS-CoV-2 (COVID-19) Infection (ICAT·COVID)

COVID-19 Pneumonia

Spain
Sebastiano Biondo
Hospital Universitari de Bellvitge

Recruiting

PILONIDAL SINUS: CONVENTIONAL CARE VERSUS NEGATIVE PRESSURE THERAPY. (SINUS-TPN)

Wound Heal | Pilonidal Sinus

Spain
Azienda Ospedaliera Sant'Anna e San Sebastiano

Unknown

Non Culprit Functional Evaluation With 3D Angio QFR in STEMI PCI Procedure

Coronary Artery Disease | Percutaneous Coronary Intervention | STEMI - ST Elevation Myocardial Infarction

Italy
Sebastian Findeisen
Bonalive Biomaterials Ltd

Recruiting

Evaluation of the Clinical Effectiveness of Bioactive Glass (S53P4) in the Treatment of Tibia and Femur Non-unions

Pseudoarthrosis of Bone

Germany
Sebastiano Biondo

Recruiting

Prospective and Multicentre Study on Clinical-biological Factors Predictive of Chronic Colon DIverticulitis (DICRO)

Acute Diverticulitis

Spain
Sebastian Wolf
University of Bern

Completed

Evaluation of Retinal Structure With High Resolution Optical Coherence Tomography (OCT)

Macular Edema | CNV

Switzerland
Dr. Jean-Sebastien Delisle, MD, PhD

Recruiting

A Study of the Safety and Efficacy of EBV Specific T-cell Lines (EBV-TCL-01)

Lymphoma | Epstein-Barr Virus Infections | Post-Transplant Lymphoproliferative Disorder

Canada
Hoffmann-La Roche
Roche Diagnostics

Completed

A Study Evaluating the Perception of Insertion Pain With Accu-Chek FlexLink and FlexLink Plus Insulin Pump Devices Under Real Life Conditions in Diabetic Patients.

Diabetes Mellitus Type 2, Diabetes Mellitus Type 1

Germany
Sebastian Zschaeck
Helmholtz Zentrum Dresden Rossendorf, Dresden, Germany

Recruiting

Functional Imaging to Identify Radiosensitive Esophageal Cancer - a Biomarker Validation Study (FIRASE)

Esophagus Cancer

Germany
University of Göttingen
UZ Gent, Belgium; Policlinica de Guipuzcoa, San Sebastian, Spain

Completed

Efficacy of a Convective Prewarming System in Prevention of Perioperative Hypothermia

Perioperative Hypothermia

Belgium, Germany, Spain
Hoffmann-La Roche
nv Roche sa

Completed

An Observational Study to Evaluate the Clinical Effectiveness, Quality of Life, Safety and Tolerability of Tocilizumab (TCZ) in Patients With Rheumatoid Arthritis (RA) in Daily Clinical Practice

Rheumatoid Arthritis

Belgium, Luxembourg
Hoffmann-La Roche
Roche Pharma AG

Completed

Influence of Ribavirin on the Initial Virological Response in Treatment Naïve Patients With Hepatitis C Genotype 1 Infection

Hepatitis C, Chronic

Germany
Hoffmann-La Roche
Roche Pharma AG

Terminated

Comparison of Ibandronate - Zoledronate Regarding Nephrotoxicity in Multiple Myeloma (COMPARE)

Multiple Myeloma

Germany
Hoffmann-La Roche
Roche Pharma AG

Completed

A Study of Trastuzumab Emtansine (Trastuzumab-MCC-DM1, T-DM1) in Combination With Pertuzumab Administered to Patients With Human Epidermal Growth Factor Receptor-2 (HER2)-Positive Locally Advanced or Metastatic Breast Cancer Who Have Previously Received Trastuzumab

Metastatic Breast Cancer

Italy, Spain, Canada, United States, Belgium, France, Germany
Hospital General Ajusco Medio
Horacio Marquez-Gonzalez; Carlos Torruco-Sotelo; Sebastian Rodriguez-Llamazares

Completed

Risk Factors for Barotrauma in COVID-19

Covid19 | Barotrauma

Mexico
Hoffmann-La Roche
Roche Molecular Systems, Inc

Not yet recruiting

A Study of the Cobas® Liat CT/NG/MG Test Versus Current Standard Practice for Managing Participants at Increased Risk of Sexually Transmitted Infections

Chlamydia Trachomatis Infection | Mycoplasma Genitalium Infection | Neisseria Gonorrhoeae Infection
Hoffmann-La Roche
Roche Diabetes Care GmbH

Completed

Comparing Continuous Subcutaneous Insulin Infusion With Multiple Daily Injections to Reach HbA1c Targets in Children and Adolescents With Type 1 Diabetes (Insight Kids)

Diabetes Mellitus Type 1

Germany, Austria, United Kingdom
Hoffmann-La Roche
Roche Diabetes Care GmbH

Completed

ACCU-CHEK Connect Personal Diabetes Management Study (PDM CONNECT)

Diabetes Mellitus, Type 1

United States
Hoffmann-La Roche
Roche Diabetes Care Deutschland GmbH

Completed

A German Study Evaluating the Efficacy and the Benefit of Integrated Personalized Diabetes Management (PDM) for Type 2 Diabetes Patients. (PDM-ProValueGP)

Diabetes Mellitus, Type 2

Germany
Hoffmann-La Roche
Roche Diabetes Care Deutschland GmbH

Completed

A Study Evaluating the Efficacy and the Benefit of Integrated Personalized Diabetes Management (PDM) for Diabetic Patients. (PDMProValueDSP)

Type II Diabetes Mellitus

Germany
Hoffmann-La Roche

Recruiting

A Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamics Of Satralizumab In Participants With Thyroid Eye Disease (SatraGO-2) (SatraGO-2)

Thyroid Eye Disease

Korea, Republic of, United States, United Kingdom, China, Canada, France, Spain
Hoffmann-La Roche

Recruiting

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma (GLOBRYTE)

Lymphoma

Korea, Republic of, United States, France, Brazil, China, Spain, Australia, Sweden, Taiwan, Italy, United Kingdom
Hoffmann-La Roche

Recruiting

A Study to Evaluate the Effectiveness and Safety of Polatuzumab in Real World Clinical Practice Among Adult Chinese Participants With Diffuse Large B-Cell Lymphoma

Diffuse Large B-Cell Lymphoma

China
Hoffmann-La Roche

Recruiting

A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States, Belgium, Australia, Israel, Bulgaria, Spain, France, United Kingdom, Denmark, Argentina, Germany, New Zealand, South Africa, Korea, Republic of, Poland, Canada, Chile, Czechia, Mexico, Netherlands, Romania, Sweden
Hoffmann-La Roche

Recruiting

A Study of Participants in China With Non-Small-Cell Lung Cancer That is Unable to be Treated With Surgery

Carcinoma, Non-Small-Cell Lung

China
Hoffmann-La Roche

Recruiting

A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study (UmbrellaMAX)

Cancer

Korea, Republic of, United Kingdom, Japan, Costa Rica, Belgium, Taiwan, Russian Federation, Mexico, Poland, France
Hoffmann-La Roche

Not yet recruiting

A Study to Investigate the Pharmacokinetics and Safety of Risdiplam in Infants With Spinal Muscular Atrophy (PUPFISH)

Muscular Atrophy, Spinal
Hoffmann-La Roche

Recruiting

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7565020 in Healthy Participants and in Participants With Chronic Hepatitis B Virus Infection

Chronic Hepatitis B

Korea, Republic of, United States, Thailand, Hong Kong, Spain, New Zealand, Bulgaria, Taiwan, France
Hoffmann-La Roche

Recruiting

GENERATION HD2. A Study to Evaluate the Safety, Biomarkers, and Efficacy of Tominersen Compared With Placebo in Participants With Prodromal and Early Manifest Huntington's Disease.

Huntington Disease

United States, Australia, Argentina, Canada, Germany, Italy, Spain, France, United Kingdom, Portugal, New Zealand, Austria, Poland, Switzerland, Denmark
Hoffmann-La Roche

Recruiting

A Study to Evaluate the Safety and Pharmacokinetics of the Intravenous Fixed-Dose Combination (IV FDC) of Tiragolumab and Atezolizumab in Participants With Locally Advanced, Recurrent or Metastatic Solid Tumors (SKYSCRAPER-11)

PD-L1-selected Solid Tumors

Korea, Republic of, United States, Spain, Taiwan, Turkey, Greece, Canada, Croatia, Serbia, Mexico, Cyprus, Georgia
Hoffmann-La Roche

Recruiting

A Study Evaluating Different Immunotherapies (LAG-3 and PD-1 With or Without TIGIT, Compared to PD-L1 Alone) in Participants With Untreated Locally Advanced Metastatic Urothelial Cancer

Urothelial Cancer

Korea, Republic of, United States, Brazil, China, France, Germany, Mexico, Poland, Denmark, Turkey, Australia, Greece, Spain, United Kingdom, Italy
Hoffmann-La Roche

Recruiting

A Study to Investigate Vamikibart in Participants With Uveitic Macular Edema (Meerkat)

Uveitic Macular Edema

Korea, Republic of, United Kingdom, China, United States, Netherlands, Canada, Israel, Austria, Brazil, Italy, Taiwan, Poland, Portugal, Mexico
Hoffmann-La Roche

Recruiting

A Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Anti-tumor Activity of RO7616789 in Advanced Small Cell Lung Cancer and Other Neuroendocrine Carcinomas

Small Cell Lung Cancer | Neuroendocrine Carcinoma

United States, Japan, Denmark, Spain, Poland
Hoffmann-La Roche

Recruiting

A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (ARNASA)

Chronic Obstructive Pulmonary Disease (COPD)

United States, China, Spain, Italy, Germany, Belgium, Korea, Republic of, Poland, Taiwan, Israel, New Zealand, Sweden, United Kingdom, Japan, Czechia, Philippines, Hong Kong, Greece, Australia, Thailand, Netherlands, Argentina, Brazil, Fran... and more
Hoffmann-La Roche

Recruiting

A Study Evaluating the Safety and Efficacy of Multiple Treatments in Participants With Multiple Myeloma (PLYCOM)

Multiple Myeloma

Korea, Republic of, Australia, Spain, France, Poland
Hoffmann-La Roche

Recruiting

A Study Of The Efficacy, Safety, And Pharmacokinetics Of The Port Delivery System With Ranibizumab In Chinese Patients With Neovascular Age-Related Macular Degeneration

Neovascular Age Related Macular Degeneration | nAMD

China
Hoffmann-La Roche

Recruiting

A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)

Locally Advanced or Metastatic Breast Cancer

France, Belgium, United States, Korea, Republic of, Taiwan, China, Italy, Argentina, Jordan, Mexico, Brazil, Germany, Portugal, Thailand, Turkey, United Kingdom, Kenya, Spain, Hungary, Colombia, India, Oman, Poland, Uganda, United Arab...
Hoffmann-La Roche

Recruiting

A Study To Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, And Pharmacodynamics Of Satralizumab In Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD) (SAkuraSun)

Neuromyelitis Optica Spectrum Disorder | NMOSD

Poland, United Kingdom, Argentina, Italy, France, United States

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