Clinical Trials Sponsored by SPARK Healthcare

Total 5168 results

West Park Healthcare Centre

Recruiting

Automated Titration for Home Oxygen Therapy

Chronic Respiratory Disease

Canada
West Park Healthcare Centre

Recruiting

Partitioned Training of Patients With Idiopathic Pulmonary Fibrosis

Lung; Disease, Interstitial, With Fibrosis

Canada
West Park Healthcare Centre

Active, not recruiting

Music During Pulmonary Rehabilitation for Patients With COPD

Chronic Obstructive Pulmonary Disease

Canada, Australia
West Park Healthcare Centre

Completed

The Prevalence of Chronic Pain in COPD and Its Clinical Implications

COPD

Canada
West Park Healthcare Centre

Completed

A Sedentary Behaviour Reduction Intervention for People With COPD

COPD

Canada
West Park Healthcare Centre

Completed

Muscle Activity and Sensation During Upright Partitioned Leg Exercise in COPD (MAPLE)

Chronic Obstructive Pulmonary Disease

Canada
West Park Healthcare Centre

Completed

Percussion Palm Cup: Safety and Usability in Infants and Children With Cystic Fibrosis (PPC)

Cystic Fibrosis in Children

Canada
West Park Healthcare Centre

Completed

Powered Assist to Improve Ambulation in Severe Lung Disease (REVIVE)

Lung Disease Chronic

Canada
West Park Healthcare Centre

Completed

Effectiveness and Feasibility of Delivering an Education Program to Patients With an Acute Exacerbation of COPD

Chronic Obstructive Pulmonary Disease With (Acute) Exacerbation

Canada
West Park Healthcare Centre

Completed

Exercise Capacity and Daily Physical Activity in Obese Subjects With Treated Obstructive Sleep Apnea

Obesity | Obstructive Sleep Apnea

Canada
West Park Healthcare Centre

Completed

Unsupported Arm Exercise and Breathing Strategy in Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

Canada
West Park Healthcare Centre

Completed

Arm Training in Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

Canada
West Park Healthcare Centre

Recruiting

Powered Assist Hip Exoskeleton to Improve Ambulation in Severe Lung Disease

Lung Disease Chronic

Canada
West Park Healthcare Centre

Recruiting

Tele-rehabilitation in Chronic Respiratory Disease: an Observational Cohort Study

Chronic Respiratory Disease

Canada
West Park Healthcare Centre

Completed

Pain in Individuals With COPD During Pulmonary Rehabilitation

Chronic Obstructive Pulmonary Disease

Canada
West Park Healthcare Centre

Completed

Single Leg Cycling in COPD: Knowledge Translation to Pulmonary Rehabilitation

Chronic Obstructive Pulmonary Disease (COPD)

Canada
West Park Healthcare Centre

Completed

Walking Speeds in Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

Canada
West Park Healthcare Centre

Completed

Does Pulmonary Rehabilitation Change Self-Selected And Maximum Sustainable Walking Speed In Patients With Lung Disease?

Chronic Lung Disease | COPD

Canada
West Park Healthcare Centre
St. Joseph's Healthcare Hamilton

Recruiting

A Non-pharmacological Cough Control Therapy

Cough | Pulmonary Fibrosis | Pulmonary Disease | ILD

Canada
HealthCore-NERI
Bayer; Besins Healthcare

Completed

Registry of Hypogonadism in Men (RHyMe)

Male Hypogonadism | Testosterone Deficiency | Androgen Deficiency

Italy, United Kingdom, Spain, Netherlands, Germany, Sweden
McMaster University
West Park Healthcare Centre

Completed

Fall Risk Assessment in COPD

Pulmonary Disease | COPD

Canada
McMaster University
West Park Healthcare Centre

Completed

Home Balance Pilot for Fall Reduction in COPD

Pulmonary Disease, Chronic Obstructive

Canada
West Park Healthcare Centre
Canadian Lung Association

Completed

Feasibility of Dance in People With COPD

COPD

Canada
Spark Therapeutics

Active, not recruiting

Long-term Follow-up Study in Subjects Who Received Voretigene Neparvovec-rzyl (AAV2-hRPE65v2)

Inherited Retinal Dystrophy Due to RPE65 Mutations
Spark Therapeutics

Completed

Dose-finding Study of SPK-8016 Gene Therapy in Patients With Hemophilia A to Support Evaluation in Individuals With FVIII Inhibitors

Hematologic Diseases | Blood Coagulation Disorders, Inherited | Coagulation Protein Disorders | Hemorrhagic Disorders | Genetic Diseases, Inborn | Genetic Diseases, X-Linked | Gene Therapy | Blood Coagulation Disorder | Gene Transfer | Adeno-Associated Virus (AAV) | Factor VIII (FVIII) | Factor VIII (FVIII)... and other conditions

United States
Spark Therapeutics

Completed

Lead-in Study to Collect Prospective Efficacy and Safety Data of Current FVIII Prophylaxis Replacement Therapy in Adult Hemophilia A Participants

Hematologic Diseases | Hemophilia A | Blood Coagulation Disorders, Inherited | Coagulation Protein Disorders | Hemorrhagic Disorders | Genetic Diseases, Inborn | Genetic Diseases, X-Linked | Blood Coagulation Disorder | Factor VIII Deficiency

United States, Australia, Thailand, Canada
SPARK Biopharma

Recruiting

SB17170 Phase 1 Clinical Trial in Solid Tumors

Solid Tumor

Korea, Republic of
SPARK Biopharma

Completed

SB17170 Phase1 Trial in Healthy Volunteer

Pharmacokinetics | Pharmacodynamics | Safety Issues | Tolerability

Korea, Republic of
Spark Therapeutics

Active, not recruiting

A Patient Registry Study for Patients Treated With Voretigene Neparvovec in US

Confirmed Biallelic RPE65 Mutation-associated Retinal Dystrophy

United States
Spark Therapeutics

Active, not recruiting

Long-Term Safety and Efficacy of Spark-Sponsored Gene Therapies in Males With Hemophilia A

Hemophilia A

United States, Canada, Australia
Spark Therapeutics

Completed

A Gene Transfer Study for Hemophilia A

Hemophilia A

United States, Australia, Canada, Israel, Thailand
Spark Therapeutics

Completed

Safety and Dose-escalation Study of AAV2-hCHM in Participants With CHM (Choroideremia) Gene Mutations

Choroideremia | CHM (Choroideremia) Gene Mutations

United States
Spark Therapeutics

Active, not recruiting

A Gene Transfer Study for Late-Onset Pompe Disease (RESOLUTE)

Lysosomal Storage Diseases | Glycogen Storage Disease Type II | Glycogen Storage Disease Type 2 | Pompe Disease (Late-onset) | Pompe Disease | LOPD | Acid Maltase Deficiency

United States, Canada, Netherlands, France, Denmark, Germany, Italy, United Kingdom
Spark Therapeutics

Active, not recruiting

Phase 1 Follow-on Study of AAV2-hRPE65v2 Vector in Subjects With Leber Congenital Amaurosis (LCA) 2

Leber Congenital Amaurosis

United States
Spark Therapeutics

Completed

Neutralizing Antibody Seroprevalence Study With a Retrospective Component in Participants With Late-Onset Pompe Disease

Lysosomal Storage Diseases | Glycogen Storage Disease Type 2 | Pompe Disease (Late-onset) | Pompe Disease | LOPD | Acid Maltase Deficiency

United States, Italy, United Kingdom, Netherlands, France, Germany
Spark Therapeutics

Completed

Safety Study in Subjects With Leber Congenital Amaurosis

Leber Congenital Amaurosis

United States
Bruyere Research Institute
Baycrest; West Park Healthcare Centre

Completed

Motivating Videos to Encourage Cycling for Geriatric Rehabilitation

Physical Activity | Aging | Geriatrics

Canada
Spark Neuro Inc.

Recruiting

SPARK Neuro REMIND Study

Cognitive Impairment | Alzheimer Disease

United States
Spark Biomedical, Inc.

Completed

Novel Earpiece for Transcutaneous Auricular Neurostimulation (tAN) for Symptoms of Opioid Withdrawal

Opioid-use Disorder | Opioid Withdrawal

United States
Icahn School of Medicine at Mount Sinai
International Biophysics Corporation; SPARK Healthcare

Terminated

Study of AffloVest in At-Risk Respiratory Patients During COVID-19 Pandemic

Covid19 | Chronic Obstructive Pulmonary Disease | Chronic Cough

United States
West Park Healthcare Centre
The Physicians' Services Incorporated Foundation

Completed

Breathing Helium-Hyperoxia During Exercise in Patients With Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

Canada
Lee Verweel
CapitalCare Group Inc.

Withdrawn

Medication Dispenser to Improve Care at Home for the Elderly

Cognitive Impairment | Medication Adherence
Roger Goldstein
Ontario Lung Association

Completed

Balance Training in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

Canada
Samantha Harrison
Ontario Lung Association

Completed

Balance Training for Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

Canada
Spark Therapeutics, Inc.

Recruiting

Study of a Gene Therapy Treatment for Hemophilia A (KEYSTONE 1)

Hemophilia A

United States
Spark Biomedical, Inc.

Completed

Transcutaneous Auricular Neurostimulation (tAN) for Symptoms of Opioid Withdrawal

Opioid-use Disorder | Opioid Withdrawal

United States
Mayo Clinic
Hennepin Healthcare Research Institute; Mountain Park Health Center

Completed

Stories for Change: Digital Storytelling Intervention for Diabetes Self-Management in the COVID-19 Pandemic (S4C - COVID-19)

Type2 Diabetes

United States
Mayo Clinic
Spark Neuro Inc.

Enrolling by invitation

Development of an EEG Diagnostic for Alzheimer's Disease

Alzheimer Disease | Mild Cognitive Impairment | Dementia With Lewy Bodies | Normal Control APOE e4 Carriers and Noncarriers

United States
Mayo Clinic
Spark Neuro Inc.

Completed

EEG Diagnostic for Repetitive Sub-concussive Head Impacts

Concussion

United States
Stanford University
SPARK (Stanford University)

Suspended

A Study of Esomeprazole in Children With Autism

Autism Spectrum Disorder | Autism

United States

Clinical Trials Sponsored by SPARK Healthcare

Sponsors and Collaborators

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