Clinical Trials Sponsored by SPIRE Hospitals

Total 99728 results

Spire, Inc.

Completed

Spire Medical Health Tag Actigraphy and Sleep Validation in Adults

Healthy Volunteers

United States
Mclean Hospital
Shire

Completed

Lisdexamfetamine Dimesylate in Residual Symptoms and Cognitive Impairment in Major Depressive Disorder.

Major Depressive Disorder

United States
Spire, Inc.
ResMed

Completed

An Exploratory, Observational, Non-interventional, Open Label, Remote Pilot Study to Assess Adherence in COPD Subjects

Severe Chronic Obstructive Pulmonary Disease | Moderate Chronic Obstructive Pulmonary Disease

United States
Seattle Children's Hospital
Shire

Completed

Sequencing Treatments for Mothers With ADHD and Their At - Risk Children (TMF)

Attention Deficit Hyperactivity Disorder

United States
Children's Specialized Hospital
Shire

Terminated

Effect of Guanfacine Extended-Release on Attention Deficit Hyperactivity Disorder (ADHD)-Associated Insomnia

Insomnia | Sleep Disorders | Attention-Deficit/Hyperactivity Disorder | Attention Deficit Disorder

United States
Massachusetts General Hospital
Shire

Completed

Healthy Lifestyle in Adults With Attention Deficit Hyperactivity Disorder

ADHD | Attention Deficit Hyperactivity Disorder

United States
Massachusetts General Hospital
Shire

Completed

Low Phosphate Diets in Patients With Early Stages of Chronic Kidney Disease

Chronic Kidney Disease

United States
Massachusetts General Hospital
Shire

Active, not recruiting

An SMS Intervention to Improve Adherence to Stimulant Medications in Adults With ADHD

Attention Deficit/Hyperactivity Disorder

United States
University Hospital, Lille
Shire

Completed

IgG Level in Primary Immunodeficiency Switching From Standard SCIG to Every Other Week HyQvia

Primary Immunodeficiency

France
Massachusetts General Hospital
Shire

Completed

Effect of Vyvanse on Driving in Young Adults With ADHD

Attention Deficit/Hyperactivity Disorder(ADHD)

United States
Massachusetts General Hospital
Shire

Completed

Cardiovascular Study of Lisdexamfetamine in Healthy and Hypertensive Attention Deficit Hyperactivity Disorder Adults

Attention Deficit Hyperactivity Disorder (ADHD)

United States
Massachusetts General Hospital
Shire

Completed

Equetro for the Treatment of Mania in Children Ages 6-12 With Bipolar Disorder

Bipolar Disorder | Mania

United States
Spire, Inc.
Clinimark, LLC

Completed

Spire Medical Health Tag Respiratory Rate Validation in Adults

Respiratory Rate

United States
William Beaumont Hospitals
Stryker Spine

Recruiting

Anterior Cervical Disectomy And Fusion Using The Tritanium® C Anterior Cervical Cage For One Or Two-Levels (STRYKER)

Degenerative Disc Disease | Cervical Disc Herniation | Cervical Disc Degeneration

United States
Stryker Spine

Not yet recruiting

Clinical Outcome Measure at Stryker Spine (COMPASS)

Degenerative Disc Disease | Degenerative Scoliosis
Shire

Recruiting

A Survey to Assess Participants' and Physicians' Knowledge, Attitudes and Behavior When Using GATTEX (GATTEX KAB)

Short Bowel Syndrome (SBS)

United States
Shire

Recruiting

Gaucher Disease Outcome Survey (GOS)

Gaucher Disease

United States
Shire

Active, not recruiting

An Extension Study of HGT-HIT-045 Evaluating Long-Term Safety and Clinical Outcomes of Idursulfase-IT in Conjunction With Elaprase in Pediatric Participants With Hunter Syndrome and Cognitive Impairment

Hunter Syndrome

United States, United Kingdom, Canada
Shire

Completed

Hunter Outcome Survey (HOS) (HOS)

Hunter Syndrome

United States
Shire

Terminated

A Study of VPRIV in Participants With Gaucher Disease Previously Treated With Other Enzyme Replacement Therapies or Substrate Reduction Therapies

Gaucher Disease

Canada
Shire

Completed

A Study to Learn if Recombinant Human Parathyroid Hormone [rhPTH(1-84)] Can Improve Symptoms and Metabolic Control in Adults With Hypoparathyroidism (BALANCE)

Hypoparathyroidism

United States, Spain, United Kingdom, Denmark, France, Norway, Belgium, Canada, Portugal, Sweden, Italy, Netherlands, Germany
Shire

Completed

Efficacy and Safety of Lanadelumab (SHP643) in Japanese Participants With Hereditary Angioedema (HAE)

Hereditary Angioedema (HAE)

Japan
Premia Spine

Active, not recruiting

A Pivotal Study of the Premia Spine TOPS™ System

Lumbar Spinal Stenosis | Degenerative Spondylolisthesis

United States
Shire

Completed

A Study of Lanadelumab to Prevent Hereditary Angioedema (HAE) Attacks in Children (SPRING)

Hereditary Angioedema

United States, Canada, Germany, Hungary, Spain
Shire
Takeda

Completed

A Study in Japanese Children With Short Bowel Syndrome Who Completed SHP633-302

Short Bowel Syndrome

Japan
Shire

Completed

Dose-Optimization Study Evaluating the Efficacy, Safety and Tolerability of Vyvanse (Lisdexamfetamine Dimesylate) in Children Aged 6-12 Diagnosed With ADHD

Attention Deficit Hyperactivity Disorder (ADHD)

United States
Shire

Completed

An Efficacy and Safety Study of Ontamalimab as Maintenance Therapy in Participants With Moderate to Severe Ulcerative Colitis (FIGARO UC 303)

Ulcerative Colitis

Spain, United States, Korea, Republic of, Lebanon, Australia, Russian Federation, Romania, Hungary, Portugal, Israel, Italy, Turkey, Croatia, Belgium, Bulgaria, Germany, Netherlands, Poland, New Zealand, Argentina, United Kingdom, Greec... and more
Shire

Completed

Fabry Outcome Survey (FOS) (FOS)

Fabry Disease

United States
Shire

Completed

Drug Use Study With Intuniv® in Australia

Attention Deficit Hyperactivity Disorder (ADHD)

Australia
Shire

Completed

Safety of SPD465 in Treating Adults With ADHD.

Attention Deficit Disorder With Hyperactivity
Shire

Completed

Replagal Enzyme Replacement Therapy for Children With Fabry Disease

Fabry Disease

Canada, United States
Shire

Completed

A Study of Extended Use of Recombinant Human Parathyroid Hormone (rhPTH(1-84)) in Hypoparathyroidism

Hypoparathyroidism | Chronic Hypoparathyroidism

United States
Shire

Completed

Long-term Effect of Lanthanum Carbonate on Bone

Hyperphosphatemia

United States, Germany, United Kingdom
Shire

Completed

Efficacy and Safety of Lanthanum Carbonate and Sevelamer Hydrochloride in Patients Receiving Haemodialysis for End Stage Renal Disease

Kidney Failure, Chronic
Shire

Completed

Efficacy and Safety of Extended-release Guanfacine Hydrochloride in Children and Adolescents Aged 6-17 Years With Attention-Deficit/Hyperactivity Disorder (ADHD)

Attention Deficit Hyperactivity Disorder

Spain, United States, Germany, Poland, Italy, Ukraine, Romania, United Kingdom, Sweden, Austria, Canada, France, Ireland
Shire

Terminated

A Phase IV Study in Subjects With Neurogenic Orthostatic Hypotension

Hypotension, Orthostatic

United States
Shire

Completed

Study of Velaglucerase Alfa Enzyme Replacement Therapy in Japanese Patients With Gaucher Disease

Gaucher Disease

Japan
Shire

Completed

Dose-optimization in Adolescents Aged 13-17 Diagnosed With Attention-deficit/Hyperactivity Disorder (ADHD) Using Extended-release Guanfacine HCl

Attention-Deficit/Hyperactivity Disorder

United States
Shire

Terminated

DELFT (Dynepo Evaluation of Long-Term Follow-Up Treatment) (DELFT)

Kidney Diseases | Anemia | Kidney Failure, Chronic | Renal Failure, Chronic

Germany
Shire

Completed

FST-100 in the Treatment of Acute Adenoviral Conjunctivitis

Acute Adenoviral Conjunctivitis

United States, India
Shire

Completed

FST-100 in the Treatment of Acute Viral Conjunctivitis

Acute Viral Conjunctivitis

United States, Brazil
Shire

Completed

The Effect of Food on the Bioavailability of a Single Dose of SSP-004184SS in Healthy Adult Subjects

Healthy

United States
Shire

Completed

Safety and Efficacy of SPD465 in Adults With ADHD

Attention Deficit Disorder With Hyperactivity

United States
Shire

Completed

Effect of SSP-004184 (SPD602) on the Pharmacokinetics of Simvastatin in Healthy Adult Subjects

Healthy

United States
Shire

Completed

Safety and Efficacy of Vyvanse in Adults With Attention-Deficit/Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder

United States
Shire

Terminated

Adjunctive SPD489 to Antipsychotic Medication in Clinically Stable Adults With Persistent Predominant Negative Symptoms of Schizophrenia

Schizophrenia

United States
Shire

Completed

Comparing Absorption of Dietary Phosphorus When Administering FOSRENOL® or RENVELA® in Healthy Adult Volunteers

Kidney Failure, Chronic

United States
Shire

Completed

The Pharmacokinetics of Rocaltrol When Administered Alone or in Combination With Fosrenol or Renvela in Healthy Volunteers

Healthy

United States
Shire

Completed

Long-term Study of Teduglutide in Pediatric Subjects With Short Bowel Syndrome Who Completed the TED-C13-003 Study

Short Bowel Syndrome

United States, United Kingdom
Shire

Completed

Safety, Tolerability, Ascending Dose and Dose Frequency Study of rhHNS Via an IDDD in MPS IIIA Patients

Mucopolysaccharidosis (MPS)

United Kingdom, Netherlands

3

Subscribe