Clinical Trials Sponsored by Sanger Institure, Cambridge

Total 20713 results

Cambridge University Hospitals NHS Foundation Trust
University of Cambridge; Cambridge Stem Cell Institute, Cambridge; Anne McLarent... and other collaborators

Unknown

Regenerative Cellular Therapies, Physiology, Pathology and Developmental Biology (RCT)

Diabetes Mellitus | Graft Rejection | Transplantation

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge; Cancer Research UK Cambridge Institute

Completed

EVIS - Ex-vivo Assessment of T-lymphocyte Homing in Primary Pancreatic Cancer (EVIS)

Pancreatic Cancer

United Kingdom
Instituto Nacional de Cancer, Brazil
Cancer Research UK Cambridge Institute

Unknown

A Study Evaluating Megestrol Acetate Modulation in Hormone Receptor Positive Advanced Breast Cancer (MEGA)

Breast Neoplasm

Brazil
Cambridge University Hospitals NHS Foundation Trust
AstraZeneca; Cancer Research UK Cambridge Institute

Recruiting

DLBCL Interim Response Evaluation for Customised Therapy (DIRECT)

High-grade B-cell Lymphoma

United Kingdom
CCTU- Cancer Theme
Breast Cancer Now; CRUK Cambridge Institute

Recruiting

Neo-RT: A Study Investigating Whether Changing the Sequence of Treatments (Starting Radiotherapy Followed by Hormone Therapy Before Surgery) is Feasible (Neo-RT)

Breast Cancer

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust; Institute of Cancer Research...

Completed

Primary Thrombocythaemia 1 Trial (PT-1)

Myeloproliferative Disorder | Thrombocythemia

United Kingdom
University of Cambridge
Cancer Research UK

Not yet recruiting

How Does Skin Tone Affect Quantitative Photoacoustic Imaging (PAISKINTONE)

Skin Abnormalities | Vitiligo
CCTU- Cancer Theme
Cambridge University Hospitals NHS Foundation Trust; University of Cambridge

Unknown

LUCID - LUng Cancer CIrculating Tumour Dna Study (LUCID)

Non Small Cell Lung Cancer

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Unknown

Neoadjuvant Epirubicin, Cyclophosphamide, and Paclitaxel With or Without Gemcitabine in Treating Women Who Are Undergoing Surgery for Early Breast Cancer

Breast Cancer

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Unknown

Pyridoxine in Preventing Hand-Foot Syndrome in Patients Who Are Receiving Capecitabine for Advanced Colorectal Cancer or Breast Cancer

Breast Cancer | Colorectal Cancer | Palmar-plantar Erythrodysesthesia

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Unknown

Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Nonmetastatic Breast Cancer

Breast Cancer | Perioperative/Postoperative Complications | Cardiac Toxicity

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Completed

Capecitabine and Streptozocin With or Without Cisplatin in Treating Patients With Unresectable or Metastatic Neuroendocrine Tumors

Islet Cell Tumor | Gastrointestinal Carcinoid Tumor

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Completed

Vatalanib in Treating Patients With Metastatic Cutaneous Melanoma That Cannot be Removed by Surgery

Melanoma (Skin)

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Completed

Symptom Control With or Without Docetaxel in Treating Patients With Relapsed Esophageal Cancer or Stomach Cancer

Pain | Gastric Cancer | Esophageal Cancer | Adenocarcinoma of the Gastroesophageal Junction | Nausea and Vomiting

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Completed

Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors

Testicular Germ Cell Tumor | Teratoma | Extragonadal Germ Cell Tumor

United Kingdom
CCTU- Cancer Theme
AstraZeneca; Cancer Research UK; University of Cambridge

Recruiting

WIRE - Novel Treatments in Renal Cell Cancer (WIRE)

Renal Cell Cancer

United Kingdom
CCTU- Cancer Theme
University of Cambridge; Microsoft Research

Recruiting

Heuristics, Algorithms and Machine Learning: Evaluation & Testing in Radiation Therapy (Hamlet rt)

Cancer

United Kingdom
CCTU- Cancer Theme
Sanofi; National Institute for Health Research, United Kingdom; Stand Up To Cancer and other collaborators

Completed

To Assess the Safety of Continuous IV Administration of Plerixafor in Patients With Advanced Pancreatic, Ovarian and Colorectal Cancers (CAM-PLEX)

Colorectal Cancer Metastatic | Ovarian Serous Adenocarcinoma | Pancreatic Adenocarcinoma Metastatic

United Kingdom
CCTU- Cancer Theme
Cambridge Cellular Therapies Laboratory; The Evelyn Trust

Unknown

A Study to Collect Bone Marrow for Process Development and Production of BM-MSC to Treat Severe COVID19 Pneumonitis (COMET20d)

Healthy Volunteers for Bone Marrow Donation

United Kingdom
CCTU- Cancer Theme

Unknown

Evaluation of Novel Diagnostic Tests for COVID-19 (COVIDx)

Acute Disease | Coronavirus | Respiratory Viral Infection

United Kingdom
Cambridge Health Alliance
National Institute of Mental Health (NIMH)

Recruiting

Prevention and Early Identification for High Risk Youth in School-based Clinics

Resilience, Psychological | Screening | Health Equity | Community Mental Health Services | Adolescent Well Being

United States
University of Cambridge
Medical Research Council; Cancer Research UK

Active, not recruiting

The European Prospective Investigation Into Cancer in Norfolk Prospective Population Study (EPIC-Norfolk)

Cardiovascular Diseases | Neoplasms | Death
International Agency for Research on Cancer
University of Cambridge; Kilimanjaro Clinical Research Institute

Completed

Cytosponge™ Feasibility Study in Tanzania (CytoSCCAPE)

Esophageal Diseases | Esophagus SCC

Tanzania
CCTU- Cancer Theme

Recruiting

Metabolic and Immunological Phenotyping in Patients With Cancer (MIPPaC)

Cancer | Non-Hematologic Malignancy

United Kingdom
CCTU- Cancer Theme

Unknown

Identification of Novel Biomarkers of Response to Systemic Treatments in Renal Cell Cancer (ARTIST_RCC)

Carcinoma, Renal Cell
Quadram Institute Bioscience
Cambridge University Hospitals NHS Foundation Trust

Terminated

Utilizing MRI to Study the Effect of Sulforaphane on Prostate Cancer (ESCAPE-ING)

Prostate Cancer

United Kingdom
Cambridge Health Alliance
Stanley Medical Research Institute; Mclean Hospital

Terminated

Taurine in Adolescents With Bipolar Disorder

Bipolar Disorder

United States
Cambridge University Hospitals NHS Foundation Trust
Boehringer Ingelheim; Cancer Research UK; University of Cambridge; The Brain Tumour...

Terminated

Cambridge Brain Mets Trial 1 (CamBMT1)

Breast Cancer | Advanced Breast Cancer | Lung Cancer | Brain Cancer | Advanced Lung Cancer

United Kingdom
University of Cambridge
Medical University of Graz; Cambridge University Hospitals NHS Foundation Trust and other collaborators

Completed

Short Term Closed-loop Glucose Control in Adults With Type 1 Diabetes (AP@home02)

Type 1 Diabetes

United Kingdom, Germany, Austria
CCTU- Cancer Theme
AstraZeneca

Recruiting

AZD6738 & Gemcitabine as Combination Therapy (ATRiUM)

Cancer

United Kingdom
CCTU- Cancer Theme
AstraZeneca

Unknown

Cambridge Liquid Biopsy and Tumour Profiling Study for Patients on Experimental Therapeutics Trials (CALIBRATE)

Cancer

United Kingdom
CCTU- Cancer Theme
Celgene

Completed

Scheduling Nab-paclitaxel With Gemcitabine (SIEGE)

Pancreatic Adenocarcinoma Metastatic

United Kingdom
Cambridge Health Alliance
National Institute of General Medical Sciences (NIGMS)

Not yet recruiting

Healing Lodge First Face Training Evaluation Study

Addiction | Self-harm | Trauma, Psychological | Depression/Anxiety

United States
Cambridge University Hospitals NHS Foundation Trust
AstraZeneca; Cancer Research UK

Recruiting

Platinum and Polyadenosine 5'Diphosphoribose Polymerisation Inhibitor for Neoadjuvant Treatment of Triple Negative Breast Cancer and/or Germline BRCA Positive Breast Cancer (PARTNER)

Breast Cancer

United Kingdom
CCTU- Cancer Theme
AstraZeneca

Active, not recruiting

Pre-operative Stereotactic Ablative Body Radiotherapy Followed by Immediate Surgery for Pancreatic Cancer (PORTICO-SABR)

Cancer of Pancreas

United Kingdom
Cambridge Health Alliance
National Cancer Institute (NCI); National Center for Complementary and Integrative...

Recruiting

Patients' Attitudes Toward and Experiences With Buprenorphine Treatment

Opioid-Related Disorders | Opioid-use Disorder | Acceptability of Health Care

United States
CCTU- Cancer Theme
Cambridge University Hospitals NHS Foundation Trust; Cancer Research UK; Celgene

Terminated

Pancreatic Resectability in Cancers With Known Limited Extension (PRICKLE) (PRICKLE)

Pancreatic Adenocarcinoma

United Kingdom
Papworth Hospital NHS Foundation Trust
Cancer Research UK; University of Cambridge

Recruiting

Second Primary Lung Cancer Cohort Study (SPORT) (SPORT)

Lung Cancer

United Kingdom
CCTU- Cancer Theme
Microbiotica Ltd

Recruiting

Microbiome Immunotherapy Toxicity and Response Evaluation

Melanoma | Lung Cancer | Renal Cancer

United Kingdom
Owlstone Ltd
Cambridge University Hospitals NHS Foundation Trust; Cancer Research UK

Completed

PAN-study: Pan-Cancer Early Detection Study (PAN)

Gastric Cancer | Esophageal Cancer | Liver Cancer

United Kingdom
Centre Hospitalier du Luxembourg
University of Cambridge; Luxembourg Institute of Health

Completed

Adolescence and Diabetes:Can an Automated Closed Loop System Improve Control ? (SPIDIMAN2)

Type1 Diabetes Mellitus

Luxembourg
University of Cambridge
Imperial College London; Cambridge University Hospitals NHS Foundation Trust; Wellcome Trust and other collaborators

Active, not recruiting

PET Imaging of Giant Cell and Takayasu Arteritis (PITA)

Giant Cell Arteritis | Takayasu Arteritis

United Kingdom
Mount Sinai Hospital, Canada
Cambridge University Hospitals NHS Foundation Trust; University of Cambridge; Jaeb Center for Health Research and other collaborators

Completed

Continuous Glucose Monitoring in Women With Type 1 Diabetes in Pregnancy Trial (CONCEPTT)

Type 1 Diabetics Who Are Pregnant or Planning Pregnancy

Canada, United Kingdom, Spain, United States, Ireland, Italy
Cambridge University Hospitals NHS Foundation Trust
Juvenile Diabetes Research Foundation; Wellcome Trust; University of Cambridge; National Institute for Health Research, United Kingdom

Completed

Regulatory T Cells in Type 1 Diabetes Patients Treated With IL-2 (DILT1D)

Type 1 Diabetes

United Kingdom
CCTU- Cancer Theme
Janssen-Cilag Ltd.

Completed

Therapeutics in Active Prostate Cancer Surveillance (TAPS01)

Prostate Cancer

United Kingdom
Boston VA Research Institute, Inc.
Mclean Hospital; Cambridge Health Alliance; Northeastern University

Recruiting

Real-time fMRI Neurofeedback in Patients With Schizophrenia and Auditory Hallucinations

Schizophrenia | Treatment-resistant Schizophrenia | Auditory Hallucination

United States
CCTU- Cancer Theme
Cambridge University Hospitals NHS Foundation Trust; Cancer Research UK; Experimental...

Active, not recruiting

Predicting Sites of Tumour Progression in the Invasive Margin of Glioblastomas (PRaM-GBM Study) (PRaM-GBM)

High Grade Glioma

United Kingdom
CCTU- Cancer Theme
Pierre Fabre Medicament

Not yet recruiting

Perioperative Encobini in BRAFV600 Mutant Stage III (B/C/D) or Oligometastatic Stage IV Melanoma (PREMIUM)

Melanoma | Cancer

United Kingdom
University of Cambridge
University of Oxford; Stanley Medical Research Institute; McPin Foundation

Completed

Study of Immunotherapy in Autoantibody Positive Psychosis (SINAPPS-1)

Schizophrenia | Psychosis | Auto Immune Disorders

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Cambridge University Hospitals NHS Foundation...

Completed

Quantification of Breast RadioTherapy Associated Late Toxicity Using Novel UltraSound Techniques (QuaRTUS)

Breast Radiotherapy Toxicity

United Kingdom

Clinical Trials Sponsored by Sanger Institure, Cambridge

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Malawi

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Rare Diseases

Drug Interventions

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