Clinical Trials Sponsored by Scios, Inc

Total 35386 results

Scios, Inc.

Completed

A Study of Short-Term Outcomes and Economic Impact For Patients With Worsening Congestive Heart Failure When Natrecor (Nesiritide) is Added to Standard-Care Therapy, Compared to Administration of Placebo With Standard-Care Therapy

Cardiomyopathies | Heart Failure, Congestive | Dyspnea, Paroxysma
Scios, Inc.

Completed

Evaluation of Combined Action Between Natrecor and Furosemide on Kidney and Neurohormone Responses in Chronic Heart Failure: A Phase-IV study704.351 / DSS

Chronic Heart Failure | Congestive Heart Failure
Scios, Inc.

Completed

Clinical Study to Evaluate Nesiritide in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery A014 / NAPA

Coronary Heart Disease | Ischemic Heart Disease | Cardiopulmonary Bypass | Congestive Heart Failure | Coronary Artery Bypass Surgery | Coronary Artery Bypass Grafting
Scios, Inc.

Completed

SPRiNG: SCIO-469 Patients With Rheumatoid Arthritis Not Receiving Methotrexate

Arthritis, Rheumatoid
Scios, Inc.

Completed

Registry for Acute Decompensated Heart Failure Patients Admitted to the ER

Heart Failure, Congestive | Heart Decompensation
Scios, Inc.

Completed

Safety Study of SCIO-469 to Treat Patients With Active Rheumatoid Arthritis Receiving Methotrexate

Rheumatoid Arthritis
Scios, Inc.

Withdrawn

An Efficacy and Safety Study for Nesiritide in Heart Failure Patients With Reduced Kidney Function Undergoing Coronary Artery Bypass Graft Surgery Requiring Cardiopulmonary Bypass (CPB Pump or Heart Lung Machine)

Coronary Heart Disease | Ischemic Heart Disease | Cardiopulmonary Bypass | Heart Failure, Congestive | Coronary Artery Bypass Surgery | Coronary Artery Bypass Grafting
Scios, Inc.

Completed

SCIO-469: Open-Label Study for Patients With Myelodysplastic Syndromes.

Myelodysplastic Syndromes | Bone Marrow Diseases | Hematologic Diseases | Bone Marrow Neoplasms
Scios, Inc.

Completed

A Study of the Safety and Efficacy of Follow-up Serial Infusions of Natrecor(Nesiritide) for the Management of Patients With Heart Failure

Heart Failure, Congestive
Scios, Inc.

Completed

A Study of Oral SCIO-469 Pharmacokinetics (Study of a Drug in the Body to Watch How the Drug is Absorbed, Distributed, Metabolized and Eliminated Over a Period of Time) in the Body of Female Patients With Active Rheumatoid Arthritis

Rheumatoid Arthritis
Scios, Inc.

Completed

Extension Study of the Efficacy and Safety of Oral SCIO-469 in Relapsed, Refractory Patients With Multiple Myeloma

Multiple Myeloma
Scios, Inc.

Completed

Registry for Acute Decompensated Heart Failure Patients

Heart Failure, Congestive | Heart Decompensation
Scios, Inc.

Terminated

Natrecor (Nesiritide) in Transplant-Eligible Management of Congestive Heart Failure-TMAC

Renal Insufficiency | Renal Failure | Congestive Heart Failure | Cardiac Transplantation

United States
Scios, Inc.

Completed

Heart Failure Registry

Heart Failure, Congestive
Scios, Inc.

Completed

A Study Testing the Effectiveness of Nesiritide in Patients With Acute Decompensated Heart Failure

Heart Decompensation

United States, Australia, France, Poland, China, Germany, Taiwan, Argentina, Colombia, Israel, Mexico, Bulgaria, India, Malaysia, Ukraine, Canada, Greece, Korea, Republic of, Chile, New Zealand, Singapore, Brazil, Russian Federation, ... and more
Scios, Inc.

Completed

FUSION I Assesses Safety and Tolerability of Two Doses of NATRECOR (Nesiritide) Administered to Patients With Worsening Congestive (Decompensated) Heart Failure Who Are Concurrently Receiving Their Usual Cardiac Medications and Are at High Risk for Hospitalization.

Heart Failure, Congestive
Scios, Inc.

Completed

A Safety Study Comparing Natrecor (Nesiritide) Versus Dobutamine Therapy for Worsening Congestive Heart Failure

Heart Failure, Congestive
Scios, Inc.

Completed

A Study Comparing Blood Flow and Clinical and Safety Effects of the Addition of Natrecor (Nesiritide), Placebo or Intravenous Nitroglycerin to Standard Care for the Treatment of Worsening Congestive Heart Failure.

Symptomatic Decompensated Congestive Heart Failure | Congestive Heart Failure in Acute Coronary Syndrome
Scios, Inc.

Completed

A Study of Two Doses of Intravenous NATRECOR hBNP (Nesiritide) in Patients With Worsening Congestive Heart Failure Who Have Difficulty Breathing at Rest

Heart Failure, Congestive | Heart Decompensation
Scios, Inc.

Completed

A Study to Develop Additional Safety and Clinical Experience With NATRECOR hBNP (Nesiritide) in the Treatment of Patients With Worsening Congestive Heart Failure Who Require Inpatient Intravenous Therapy With Medications That Influence the Tone and Caliber of Blood Vessels

Heart Failure, Congestive | Heart Decompensation
Scios, Inc.

Completed

Study of Oral SCIO-469 in Relapsed, Refractory Patients With Multiple Myeloma

Multiple Myeloma
Scios, Inc.

Completed

Longitudinal Registry for Advanced Heart Failure Patients

Heart Failure, Congestive | Heart Decompensation
Stanford University
Scios, Inc.

Completed

BNP for Cardio-Renal Decompensation Syndrome (BNP-CARDS)

Renal Insufficiency | Congestive Heart Failure Exacerbation

United States
Emory University
Scios, Inc.

Terminated

BNP Therapy Observation Unit Outcomes STudy (BOOST) (BOOST)

Congestive Heart Failure

United States
Mayo Clinic
Scios, Inc.

Completed

Brain Natriuretic Peptide (BNP) to Preserve Renal Function in Hospitalized Patients With Heart Failure

Kidney Diseases | Congestive Heart Failure | Cardiomyopathy

United States
Mayo Clinic
Scios, Inc.

Completed

BNP (Nesiritide) vs. Placebo to Protect Kidney Function in Patients Undergoing Heart Bypass Surgery.

Acute Kidney Failure

United States
Massachusetts General Hospital
Scios, Inc.

Completed

Study of Nesiritide in Diastolic Heart Failure.

Diastolic Heart Failure
University of Rochester
Scios, Inc.

Completed

Nesiritide and Vo2 Max in Heart Failure Patients

Heart Failure

United States
University of Chicago
Scios, Inc.

Terminated

Nesiritide in Chronic Heart Failure

Heart Failure

United States
University of Wisconsin, Madison
Scios, Inc.

Completed

Catheterization Laboratory Study: Acute Responses in Diastolic Heart Failure

Heart Failure, Congestive

United States
University of Wisconsin, Madison
Scios, Inc.

Completed

Heart and Blood Pressure Study: The Effect of Aortic Impedance on Myocardial Relaxation

High Blood Pressure

United States
Brigham and Women's Hospital
Scios, Inc.

Completed

Nesiritide Infusion for the Treatment of Decompensated Heart Failure and Renal Dysfunction

Renal Insufficiency | Congestive Heart Failure

United States
University of California, Los Angeles
Scios, Inc.

Completed

Nesiritide - Dilated Cardiomyopathy

Dilated Cardiomyopathy

United States
University of Texas Southwestern Medical Center
Scios, Inc.

Completed

Impact of Nesiritide Infusion for Decompensated Heart Failure in the Emergency Department

Heart Failure, Congestive | Cardiomyopathy

United States
Scion NeuroStim

Recruiting

STEM-Parkinson's Disease

Parkinson Disease | Parkinson's Disease and Parkinsonism

United States, United Kingdom
Scion NeuroStim

Enrolling by invitation

STEM-PD Open Label Extension (OLE)

Parkinson Disease | Parkinson's Disease and Parkinsonism

United States
Scion NeuroStim

Terminated

A Non-Invasive Neuromodulation Device for Prevention of Episodic Migraine Headache

Intervention

United States, United Kingdom
Scion NeuroStim

Completed

A Non-Invasive Neuromodulation Device for Treatment of Migraine Headache

Migraine Headache, Episodic

United States, United Kingdom
Scion NeuroStim

Completed

A Pilot Study of a Non-Invasive Neuromodulation Device for Treatment of Parkinson's Disease

Parkinson's Disease

United States
Scion NeuroStim

Completed

Neurostimulation Device for Treatment of Migraine Headache

Migraine Headache

United States
Scion NeuroStim

Completed

Examining the Effects of Neuromodulation on Glucose Metabolism in Type 2 Diabetes

Type 2 Diabetes

United States
Scion NeuroStim

Not yet recruiting

WeArable Neuromodulation DeVice for the TrEatment of Alzheimer's Disease (WAVE-AD)

Alzheimer Disease
Duke University
Scion NeuroStim

Completed

Caloric Stimulation on Cerebral Blood Flow

Healthy Volunteer

United States
Scion NeuroStim
Duke University

Completed

Effects of Neuromodulation on Verbal Fluency in Post-stroke Aphasia

Post-stroke Aphasia

United States
University of Miami
Scion NeuroStim

Withdrawn

Neuromodulation Treatment of Vestibular Migraines

Headache

United States
Scius Healthcare Solutions Pty Ltd
Chiesi Australia

Not yet recruiting

Interpreting Respiratory Oscillometry in Adult Asthma and COPD: a Delphi Study

Chronic Obstructive Pulmonary Disease | Asthma
University of Medicine and Dentistry of New Jersey
Scios, Inc.

Withdrawn

Double Blind Randomized Placebo Controlled Trial of Natrecor in Acute Decompensated Heart Failure With Normal EF

Pulmonary Edema | Dyspnea | Heart Failure, Congestive

United States
Centre for Addiction and Mental Health
Scion NeuroStim

Recruiting

The Effects of Non-invasive Neuromodulation on Illness Awareness in Schizophrenia

Schizophrenia | Anosognosia

Canada
Scion NeuroStim
Centre for Addiction and Mental Health

Not yet recruiting

Neuromodulation for Schizophrenia

Schizophrenia

Canada
Scion NeuroStim
National Institute of Neurological Disorders and Stroke (NINDS)

Not yet recruiting

SHARPEN - Parkinson's Disease Dementia (SHARPEN)

Parkinson Disease Dementia

3

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