Clinical Trials Sponsored by Selecta Biosciences, Inc.

Total 710 results

Selecta Biosciences, Inc.

Completed

Safety and Pharmacodynamics of SEL-212 (Pegsiticase + SEL-110) in Subjects With Elevated Blood Uric Acid Levels

Gout

United States
Selecta Biosciences, Inc.

Completed

Safety and Pharmacodynamics of SEL-068 Vaccine in Smokers and Non-Smokers

Smoking Cessation

Belgium
Selecta Biosciences, Inc.

Completed

A Study to Compare the Efficacy of SEL-212 to KRYSTEXXA® in Gout Participants Refractory to Conventional Therapy (COMPARE)

Chronic Gout

United States
Selecta Biosciences, Inc.

Completed

Safety and Pharmacodynamics of SEL-037 (Pegsiticase) in Subjects With Elevated Blood Uric Acid Levels

Gout

United States
Selecta Biosciences, Inc.

Completed

Multi-Dose Safety/Pharmacodynamic Study of SEL-212/SEL-037 in Subjects With Symptomatic Gout & Elevated Blood Uric Acid

Hyperuricemia | Gout Chronic

United States
Selecta Biosciences, Inc.

Completed

Safety and Pharmacodynamcis of SELA-070 Nicotine Vaccine in Smokers

Smoking Cessation

Belgium
Selecta Biosciences, Inc.
National Human Genome Research Institute (NHGRI)

Suspended

A Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SEL-302 in Pediatric Subjects With MMA (reiMMAgine)

Methylmalonic Acidemia (MMA)

United States
Electra Therapeutics Inc.

Recruiting

Evaluation of the Safety and Efficacy of ELA026 in Participants With Secondary Hemophagocytic Lymphohistiocytosis

Secondary Hemophagocytic Lymphohistiocytosis (sHLH)

Netherlands, United States, Spain, Austria, United Kingdom, Italy
Electra Therapeutics Inc.

Completed

Evaluation of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ELA026 in Single and Multiple Doses in Healthy Volunteers

Healthy Volunteers

United States, Austria
Coherus Biosciences, Inc.
Shanghai Junshi Bioscience Co., Ltd.; Medpace, Inc.

Active, not recruiting

Study to Evaluate Safety and PK of CHS-006 in Combination With Toripalimab in Patients With Advanced Solid Tumors

Hepatocellular Carcinoma | Non-Small Cell Lung Cancer | Advanced Solid Tumor

United States
LegoChem Biosciences, Inc
AntibodyChem Biosciences, Inc.

Recruiting

A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

Advanced Solid Tumors

United States, Canada
IGM Biosciences, Inc.

Recruiting

A Study of Imvotamab in Severe Systemic Lupus Erythematosus

Systemic Lupus Erythematosus | Lupus Erythematosus

United States, Korea, Republic of, Poland
Neodyne Biosciences, Inc.

Recruiting

De-tensioning Patch, in Subjects With Type 1 Diabetes and Lipohypertrophy

Insulin Resistance | Lipohypertrophy

Germany
Arcus Biosciences, Inc.

Recruiting

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers (ARC-25)

Cervical Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Bladder Cancer | Advanced Cancer | Non-Small Cell Lung Cancer (NSCLC) | Advanced Malignancies | Renal Cell Carcinoma (RCC) | Triple Negative Breast Cancer (TNBC) | Head and Neck Squamous Cell Carcinoma (HNSCC) | Gastroesophageal-junction...

United States
Avidity Biosciences, Inc.

Recruiting

Phase 1/2 Study of AOC 1020 in Adults With Facioscapulohumeral Muscular Dystrophy (FSHD) (FORTITUDE)

Muscular Dystrophies | Muscular Dystrophy, Facioscapulohumeral | FSHD | Facio-Scapulo-Humeral Dystrophy | FMD | Facioscapulohumeral Muscular Dystrophy 1 | FSHD2 | FSHD1 | FMD2 | Fascioscapulohumeral Muscular Dystrophy | Fascioscapulohumeral Muscular Dystrophy Type 1 | Fascioscapulohumeral Muscular Dystrophy... and other conditions

United States, United Kingdom, Canada
Tyra Biosciences, Inc

Recruiting

Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations (SURF301)

Solid Tumor | Bladder Cancer | Advanced Solid Tumor | Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Solid Tumor, Adult | FGFR3 Gene Mutation | Urinary Tract Cancer | Locally Advanced Urothelial Carcinoma | Advanced Urothelial Carcinoma | Non-muscle-invasive Bladder Cancer | FGFR3 Gene Alteration | Urinary... and other conditions

Australia, United States, France, Spain
Arcus Biosciences, Inc.

Recruiting

A Phase 1 Study of AB521 in Renal Cell Carcinoma and Other Solid Tumors (ARC-20)

Clear Cell Renal Cell Carcinoma | Solid Tumors

Korea, Republic of, United States
LegoChem Biosciences, Inc

Recruiting

A Phase 2a Study, Effect of Vancomycin With vs Without Delpazolid (LCB01-0371) in Patients With MRSA Bacteremia

MRSA Bacteremia

Korea, Republic of
Cogent Biosciences, Inc.

Recruiting

(Peak) A Phase 3 Randomized Trial of CGT9486+Sunitinib vs. Sunitinib in Subjects With Gastrointestinal Stromal Tumors

Metastatic Cancer | Advanced Gastrointestinal Stromal Tumors

United States, Korea, Republic of, Spain, United Kingdom, Australia, France, Italy, Netherlands, Taiwan, Germany, Denmark, Hong Kong, Canada, Sweden, Norway, Mexico, Czechia, Argentina, Hungary, Brazil, Chile, Poland
Senhwa Biosciences, Inc.

Recruiting

Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation

Advanced Solid Tumor

United States, Canada
FlightPath Biosciences, Inc.

Recruiting

Biomarker Study of Previously Treated Lyme Disease Volunteers in Comparison to Healthy Volunteers

Lyme Disease

United States
Precision BioSciences, Inc.

Recruiting

Dose-escalation Study of Safety of PBCAR19B in Participants With CD19-expressing Malignancies

Hematologic Malignancy | CD19 Expressing Malignancies

United States
IGM Biosciences, Inc.

Recruiting

Phase 1a/1b Study of Aplitabart (IGM-8444) Alone or in Combination in Participants With Relapsed, Refractory, or Newly Diagnosed Cancers

Sarcoma | Acute Myeloid Leukemia | Colorectal Cancer | Solid Tumor | Chronic Lymphocytic Leukemia | Non Hodgkin Lymphoma | Chondrosarcoma | Small Lymphocytic Lymphoma

United States, Korea, Republic of, France, Spain, Australia
LigaChem Biosciences, Inc.

Active, not recruiting

Study to Evaluate the Efficacy of Delpazolid as Add-on Therapy in Refractory Mycobacterium Abscessus Complex

Mycobacterium Abscessus Infection | Nontuberculous Mycobacterium Infection

Korea, Republic of
Scioto Biosciences, Inc.

Completed

28-Day Daily-dose Crossover Study of the Safety and Tolerability of SB-121 (Lactobacillus Reuteri With Sephadex® and Maltose) in Subjects, Ages 15 to 45 Years, Diagnosed With Autistic Disorder

Autistic Disorder

United States
Avidity Biosciences, Inc.

Completed

Study of AOC 1001 in Adult Myotonic Dystrophy Type 1 (DM1) Patients (MARINA)

Myotonic Dystrophy | Myotonic Disorders | Myotonic Dystrophy Type 1 (DM1) | Myotonic Dystrophy 1 | Myotonic Muscular Dystrophy | DM1 | Dystrophy Myotonic | Steinert Disease

United States
Senhwa Biosciences, Inc.

Completed

A Study of Silmitasertib (CX-4945) in Healthy Subject

COVID-19

Taiwan
Aptose Biosciences Inc.

Active, not recruiting

A Study of CG-806 in Patients With Relapsed or Refractory CLL/SLL or Non-Hodgkin's Lymphomas

Non-Hodgkin's Lymphoma | Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
Pulse Biosciences, Inc.

Completed

CellFX Comparison to Cryosurgery in Cutaneous Non-Genital Common Warts

Warts | Warts Hand | Verruca

United States
Pulse Biosciences, Inc.

Terminated

Nano-Pulse Stimulation (NPS) in Seborrheic Keratosis Optimization Study

Skin Lesion | Seborrheic Keratosis | Lesion Skin | Benign Skin Tumor

United States
Emalex Biosciences Inc.

Completed

Ecopipam Tablets to Study Tourette's Syndrome in Children and Adolescents (D1AMOND)

Tourette Syndrome

United States, Poland, France, Canada, Germany
Precision BioSciences, Inc.

Terminated

A Dose-escalation Study to Evaluate the Safety and Clinical Activity of PBCAR269A, With or Without Nirogacestat, in Study Participants With Relapsed/Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma

United States
Evelo Biosciences, Inc.

Terminated

A Long-Term Extension Trial in Participants With Atopic Dermatitis Who Participated in Previous EDP1815 Trials

Atopic Dermatitis

United States, Australia, Bulgaria, Canada, Germany, Poland
Pulse Biosciences, Inc.

Completed

Nano-Pulse Stimulation (NPS) in Seborrheic Keratosis Study

Seborrheic Keratosis | Lesion Skin

United States
Altesa Biosciences, Inc.

Enrolling by invitation

Phase 1 Study Into Pharmacokinetics and Food Effect of Vapendavir in Healthy Participants and Participants With COPD

Healthy | Pulmonary Disease | COPD | Respiratory Disease | Lower Respiratory Disease

United States
Avidity Biosciences, Inc.

Active, not recruiting

Extension of AOC 1001-CS1 (MARINA) Study in Adult Myotonic Dystrophy Type 1 (DM1) Patients (MARINA-OLE)

Nervous System Diseases | Genetic Diseases, Inborn | Musculoskeletal Diseases | Muscular Diseases | Neuromuscular Diseases | Neurodegenerative Diseases | Muscular Dystrophies | Muscular Disorders, Atrophic | Heredodegenerative Disorders, Nervous System | Myotonic Dystrophy | Myotonic Disorders | Myotonic Dystrophy... and other conditions

United States
Vedanta Biosciences, Inc.

Completed

Phase 2 Study of VE303 for Prevention of Recurrent Clostridioides Difficile Infection (CONSORTIUM)

Clostridium Difficile Infection | Clostridium Difficile Infection Recurrence | Clostridium Difficile | CDI | Clostridioides Difficile Infection | Clostridioides Difficile | Clostridioides Difficile Infection Recurrence

United States, Canada
Evelo Biosciences, Inc.

Completed

Evaluation of the Immunopharmacology of EDP1815 and EDP2939

KLH and Imiquimod Induced Skin Inflammation in Healthy Volunteers

Netherlands
Nanospectra Biosciences, Inc.

Active, not recruiting

An Extension Study MRI/US Fusion Imaging and Biopsy in Combination With Nanoparticle Directed Focal Therapy for Ablation of Prostate Tissue

Neoplasms of the Prostate

United States
Cellectar Biosciences, Inc.

Active, not recruiting

Dose Escalation Study of CLR 131 in Children, Adolescents, and Young Adults With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma (CLOVER-2)

Osteosarcoma | Ewing Sarcoma | Neuroblastoma | Rhabdomyosarcoma | Pediatric Brain Tumor | DIPG | Pediatric Solid Tumor | Pediatric Lymphoma

United States, Australia, Canada
Aramis Biosciences, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, and Efficacy of A197 in Subjects With Dry Eye Disease

Dry Eye Disease

United States
Calithera Biosciences, Inc

Terminated

Study of Mivavotinib (CB-659) in Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

Non-GCB/ABC Diffuse Large B-Cell Lymphoma | With and Without MyD88 and/or CD79B Mutations

United States
Pardes Biosciences, Inc.

Active, not recruiting

PBI-0451 (Pomotrelvir) Phase 2 Study in Nonhospitalized Symptomatic Adults With COVID-19

COVID-19

United States
Cortice Biosciences, Inc.

Suspended

Dose-Escalation Study of TPI 287 + Avastin Followed by Randomized Study of the Same Versus Avastin for Glioblastoma

Glioblastoma Multiforme

United States
Evopoint Biosciences Inc.

Completed

Pharmacokinetics of XNW4107 in Subjects With Various Degrees of Renal Function

Bacterial Infections

United States
Evopoint Biosciences Inc.

Completed

Study to Evaluate Safety, Tolerability, and Pharmacokinetics of XNW4107 Alone or in Combination With Imipenem/Cilastatin

Bacterial Infections

United States
Calithera Biosciences, Inc

Completed

Safety and Efficacy Study of Sapanisertib in Combination With Exemestane or Fulvestrant in Postmenopausal Women With Estrogen Receptor Positive/Human Epidermal Growth Factor Receptor 2 Negative (ER+/HER2-) Metastatic Breast Cancer

Breast Cancer

United States, Belgium, France
Calithera Biosciences, Inc

Withdrawn

A Study to Assess Mass Balance, Pharmacokinetics (PK), and Metabolism of Orally Administered [14 C]-TAK-659 in Participants With Advanced Solid Tumor and/or Lymphoma Malignancies

Advanced Solid Neoplasms | Lymphoma Neoplasms
Precision BioSciences, Inc.

Completed

Dose-escalation Study of Safety of PBCAR20A in Subjects With r/r NHL or r/r CLL/SLL

Lymphoma, Non-Hodgkin | Chronic Lymphocytic Leukemia | B-cell Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma | B-cell Non Hodgkin Lymphoma | Leukemia, Lymphocytic, Chronic | Non-Hodgkin's Lymphoma, Relapsed | Non-Hodgkin's Lymphoma Refractory | Chronic Lymphoid Leukemia in Relapse

United States
Calithera Biosciences, Inc

Completed

Effect of Sapanisertib (MLN0128) on the QTc Interval in Participants With Advanced Solid Tumors

Advanced Solid Tumors

United States

Clinical Trials Sponsored by Selecta Biosciences, Inc.

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mauritania

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Rare Diseases

Drug Interventions

Dietary Supplements

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