Clinical Trials Sponsored by Sirius Medicine

Total 14312 results

Sirius Medicine

Completed

Radiation Therapy and Sargramostim in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
Sirius Genomics Inc.

Unknown

Pharmacogenomic Biomarker Study for Recombinant Human Activated Protein C Treatment in Severe Sepsis

Septic Shock | Severe Sepsis

United States, Canada, France, United Kingdom
Sirius Therapeutics Co., Ltd.

Recruiting

A Phase 1 Study to Evaluate the Safety, Tolerability, PK/PD of SRSD107 in Healthy Participants

Thrombosis

Australia
Heinrich-Heine University, Duesseldorf
SIRIO MEDICINE

Withdrawn

The RESTORE-SIRIO Randomized Controlled Trial (RESTORE-SIRIO)

Percutaneous Coronary Intervention | Acute ST-segment Elevation Myocardial Infarction | No-reflow Phenomen

Germany
Cirius Therapeutics, Inc.

Not yet recruiting

A Study of MSDC-0602K to Assess Glycemic Control and Cardiovascular Outcomes in Patients With Pre-T2D or T2D and NAFLD/NASH

Type2 Diabetes | Nonalcoholic Steatohepatitis | NASH - Nonalcoholic Steatohepatitis | Non-Alcoholic Fatty Liver Disease
Osiris Therapeutics

Terminated

Study to Evaluate the Safety and Efficacy of CHAM* for the Treatment of Diabetic Foot Ulcers (*OTI-15-01)

Chronic Diabetic Foot Ulcers

United States
Osiris Therapeutics

Completed

GrafixPRIME® for the Treatment of Chronic Diabetic Foot Ulcers

Foot Ulcer, Diabetic

United States
Osiris Therapeutics

Terminated

TruSkin®: Study for Treatment of Chronic Venous Leg Ulcers

Chronic Venous Leg Ulcers

United States
Osiris Therapeutics

Completed

Study to Evaluate Safety and Efficacy of GrafixPL for the Treatment of Venous Leg Ulcers

Venous Leg Ulcer

United States
Osiris Therapeutics

Completed

GrafixCORE®: Open-Label Study to Evaluate the Safety and Efficacy of GrafixCORE® for Complex Diabetic Foot Wounds

Complex Diabetic Foot Wounds

United States
Osiris Therapeutics

Completed

Grafix® DFU: Open-Label Extension Option to Evaluate Safety & Efficacy of Grafix® for Chronic Diabetic Foot Ulcers (DFU)

Diabetic Foot Ulcers

United States
Osiris Therapeutics

Terminated

TruSkin®: Study for the Treatment of Chronic Diabetic Foot Ulcers

Diabetic Foot Ulcers

United States
Circius Pharma AB

Recruiting

Performance and Safety of Otinova® Ear Spray

Otitis Externa

Sweden
Virios Therapeutics, Inc.

Completed

Fibromyalgia Outcome Research Trial Evaluating Synergistic Suppression of HSV-1 (FORTRESS)

Fibromyalgia

United States
Citius Pharmaceuticals, Inc.

Completed

Safety and Efficacy of Hydrocortisone and Lidocaine Treatment of Grade I and II Hemorrhoids (Hydro/Lido)

Hemorrhoids
Sirion Therapeutics, Inc.

Completed

Study of Cyclosporine in the Treatment of Dry Eye Syndrome (ST-603-007)

Dry Eye Syndromes

United States
Sirion Therapeutics, Inc.

Completed

Study of Difluprednate in the Treatment of Inflammation Following Ocular Surgery (ST-601A-002b)

Inflammation

United States
Sirion Therapeutics, Inc.

Completed

Study of Difluprednate in the Treatment of Inflammation Following Ocular Surgery (ST-601A-002a)

Inflammation

United States
Sirion Therapeutics, Inc.

Completed

Study of Difluprednate Ophthalmic Emulsion in the Treatment of Uveitis

Panuveitis | Anterior Uveitis
Sirion Therapeutics, Inc.

Completed

Study of Difluprednate Ophthalmic Emulsion in the Treatment of Uveitis

Anterior Uveitis
Cirius Therapeutics, Inc.
Chiltern International Inc.

Completed

A Study to Evaluate the Safety, Tolerability & Efficacy of MSDC-0602K in Patients With NASH (EMMINENCE)

Non-alcoholic Fatty Liver Disease | NASH - Nonalcoholic Steatohepatitis | Non-alcoholic Steatohepatitis

United States
Sirion Therapeutics, Inc.

Completed

Study of Difluprednate in the Treatment of Inflammation Following Ocular Surgery (ST-601-004)

Inflammation

United States
Sirion Therapeutics, Inc.

Completed

Study of Cyclosporine in the Treatment of Dry Eye Syndrome (ST-603-005)

Dry Eye Syndromes

United States
Sirion Therapeutics, Inc.

Completed

Study of Difluprednate in the Treatment of Inflammation Following Ocular Surgery (ST-601-003)

Inflammation

United States
Sirion Therapeutics, Inc.

Completed

Study of Difluprednate in the Treatment of Uveitis

Uveitis

United States
Sirion Therapeutics, Inc.

Completed

Study of Difluprednate Ophthalmic Emulsion in the Treatment of Postoperative Inflammation

Inflammation
Sirion Therapeutics, Inc.

Completed

Study of Difluprednate Ophthalmic Emulsion in Postoperative Inflammation

Inflammation
Signus Medizintechnik GmbH

Withdrawn

Single Center Study Comparing MOBIS II ST vs MOBIS PEEK (MOBIS_US)

Lumbar Disc Disease

United States
Sirion Therapeutics, Inc.

Completed

Study of Cyclosporine in the Treatment of Dry Eye Syndrome (ST-603-006)

Dry Eye Syndromes

United States
Sirion Therapeutics, Inc.

Completed

Study of Difluprednate Ophthalmic Emulsion in the Treatment of Postoperative Inflammation

Inflammation
Sirion Therapeutics, Inc.

Completed

Study of Difluprednate Ophthalmic Emulsion in the Treatment of Severe Uveitis

Panuveitis | Uveitis
Indiana University
Karius, Inc.

Completed

Next-Generation Sequencing for Pathogen Detection and Quantification in Children With Musculoskeletal Infections (KDG-002)

Osteomyelitis | Septic Arthritis | Musculoskeletal Infection | Acute Hematogenous Osteomyelitis | Pyomyositis

United States
Karius, Inc.
Stanford University

Completed

Use of NGS Cell-free Pathogen Test for Identification of Low Risk Fever & Neutropenia in Pediatric Patients

Neutropenia | Fever

United States
Karius, Inc.
Duke University

Completed

Diagnosis of Bacteremia/Septicemia and Culture Negative Endocarditis by the Karius Sequencing-Based Infectious Disease Diagnostic Assay

Bacteremia | Septicemia

United States
Karius, Inc.
Stanford University

Completed

SEP-SEQ Trial - Determining the Etiology of Sepsis Using an Infectious Disease Diagnostic Sequencing Assay

Sepsis

United States
Marius Pharmaceuticals
Syneos Health

Completed

Efficacy and Safety of Oral Testosterone Undecanoate in Hypogonadal Men

Hypogonadism, Male

United States
Bio Sidus SA

Recruiting

Switch Over Study of Biosimilar AGA for Fabry Disease (SMILE)

Fabry Disease

Argentina
Hospital Sirio-Libanes

Recruiting

Effects of Electrical Stimulation for Preventing Loss of Muscle Mass in Patients With Sepsis

Sepsis | Septic Shock

Brazil
Bio Sidus SA

Completed

PK/PD Study of 2 Agalsidase Formulations in Single Dose of 1 mg/kg Administered to Healthy Volunteers as IV Infusion

Fabry Disease

Argentina
Hospital Sirio-Libanes

Completed

Assessing the Agreement Between Endoscopic and Histopathological Diagnosis of Colorectal Sessile Serrated Lesions.

Colorectal Cancer | Colonoscopy | Adenoma Detection Rate | Adenoma Colon | Colorectal Polyp | Sessile Serrated Adenoma | Quality Indicator

Brazil
Bio Sidus SA

Unknown

Study of HEMAX PFS Versus EPREX/ ERYPO® in Predialysis Chronic Kidney Disease

Anemia of Chronic Kidney Disease

Argentina, Paraguay
Trius Therapeutics LLC

Completed

Phase 2 Study of TR-701 in Patients With Complicated Skin and Skin Structure Infections

Skin Diseases, Infectious | Skin Diseases, Bacterial

United States
Trius Therapeutics LLC

Completed

Evaluate the Absorption, Metabolism, And Excretion Of Orally Administered [14C] TR 701 In Healthy Adult Male Subjects

Healthy

United States
Trius Therapeutics LLC

Completed

TR-701 FA vs. Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infections. (ABSSSI)

Skin and Subcutaneous Tissue Bacterial Infections

United States, Argentina, Brazil, Canada, Czechia, Germany, Hungary, Latvia, Peru, Slovakia, Ukraine
Trius Therapeutics LLC

Completed

A Phase 1 Crossover Study of Blood Pressure and Heart Rate Response

Healthy Subjects

United States
Trius Therapeutics LLC

Completed

Food Effects of Single Oral Dose of 600mg TR-701

Healthy

United States
Trius Therapeutics LLC

Completed

Pharmacokinetics, Safety, and Tolerability of TR-701 Free Acid (FA) in Elderly Subjects

Healthy Subjects

United States
Trius Therapeutics LLC

Completed

Single and Multiple Ascending Dose Pharmacokinetic Study of TR701 in Healthy Adults (SAD/MAD)

Healthy Subjects

United States
Hospital Sirio-Libanes

Completed

Exploratory Study to Determine Tissue Alterations of Advanced Hepatocellular Carcinoma Induced by Electromagnetic Waves of Low Energy Amplitude Modulated to Specific Frequencies During Imaging Study by MRI

Primary or Metastatic Tumor in the Liver Parenchyma

Brazil
Trius Therapeutics LLC

Completed

A PK and Safety Study in Subjects With Hepatic Impairment

Hepatic Impairment

United States

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