Clinical Trials Sponsored by Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)

Total 30 results

Spanish Cooperative Group for the Treatment of...

Completed

Study of FOLFIRI + Panitumumab Using Ultra-selection Technology of Patients With Stage IV Colorectal Cancer Refractory to Irinotecan Without Any Mutation on KRAS, PIK3Ca, BRAF and NRAS Genes Detected With Highly Sensitive Techniques (ULTRA)

Stage IV Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...

Completed

Safety and Efficacy Study of mFOLFOX-6 Plus Cetuximab for 8 Cycles Followed by mFOLFOX-6 Plus Cetuximab or Single Agent Cetuximab as Maintenance Therapy in Patients With Metastatic Colorectal Cancer and WT KRAS Tumours (MACRO-2)

Metastatic Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...

Completed

Phase I/II Study of Nab-paclitaxel and Gemcitabine Followed by AG-mFOLFOX in Patients With Metastatic Pancreatic Adenocarcinoma (SEQUENCE)

Metastatic Pancreatic Adenocarcinoma

Spain
Spanish Cooperative Group for the Treatment of...

Completed

Safety and Efficacy Study of XELOX vs. Oxaliplatin+5-FU CI as First Line Treatment in Metastatic Colorectal Cancer

Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...

Terminated

Axitinib as Maintenance Treatment in Patients With Metastatic CRC (TTD-11-01)

Colorectal Carcinoma

Spain
Spanish Cooperative Group for the Treatment of...
Bayer

Completed

Study Comparing Different Dose Approaches of Induction Treatment of Regorafenib in MCRC (RE-ARRANGE)

Metastatic Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Sanofi

Completed

Phase II Trial to Assess FOLFIRI+Aflibercept Efficacy in Patients With Oxaliplatin-pretreated Metastatic Colorectal Cancer With or Without ACE Polymorphisms (POLAF)

Metastatic Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Amgen

Completed

Safety and Efficacy Study of Panitumumab+Irinotecan in Patients Wild-Type (WT) KRAS Metastatic Colorectal Cancer Refractory to Irinotecan Based Chemotherapy (SPECTRA) (SPECTRA)

Metastatic Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Amgen

Completed

Safety and Efficacy Study of FOLFOX4+Panitumumab vs.FOLFIRI+Panitumumab in Subjects WT KRAS Colorectal Cancer and Liver-only Metastases (PLANET)

Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Amgen

Completed

Study of First-line Single-agent Panitumumab in Frail Elderly Patients With Advanced Wild Type K-RAS Colorectal Cancer (FRAIL)

Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Amgen

Completed

Panitumumab in Combination With Irinotecan Chemotherapy as 2nd-line Therapy in Subjects With mCRC

Metastatic Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...
AstraZeneca

Recruiting

Olaparib and Durvalumab (MEDI4736) in Patients With Metastatic Pancreatic Cancer and DNA Damage Repair Genes Alterations

Metastatic Pancreatic Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Amgen

Active, not recruiting

Study to Evaluate the Efficacy of FOLFOX + Panitumumab Followed by FOLFIRI + Bevacizumab (Sequence 1) Versus FOLFOX + Bevacizumab Followed by FOLFIRI + Panitumumab (Sequence 2) in Untreated Patients With Wild-type RAS Metastatic, Primary Left-sided, Unresectable Colorectal Cancer (CR-SEQUENCE)

Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Sanofi

Completed

Study to Assess the Efficacy and Safety of Treatment With FOLFIRI-aflibercept Compared to Initial Treatment With FOLFIRI-aflibercept (for 6 Cycles) Followed by Maintenance With 5FU-aflibercept, in an Elderly Population With mCRC After Failure of an Oxaliplatin-based Regimen (AFEMA)

Metastatic Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Bayer

Terminated

Regorafenib as Single Agent in Patients With Metastatic Colorectal Cancer (mCRC) With Any RAS or BRAF Mutation Previously Treated With FOLFOXIRI Plus Bevacizumab (PREVIUM)

Colorectal Neoplasms | Metastatic Disease

Spain
Spanish Cooperative Group for the Treatment of...
Bayer

Completed

Regorafenib in Frail and/or Unfit for Chemotherapy Patients With Metastatic Colorectal Cancer (REFRAME)

Colorectal Neoplasms | Metastatic Disease

Spain
Spanish Cooperative Group for the Treatment of...
Roche Pharma AG

Completed

Study of 5-Fluorouracil/Leucovorin/Oxaliplatin (FOLFOX) + Bevacizumab Versus 5-Fluorouracil/Leucovorin/Oxaliplatin/Irinotecan (FOLFOXIRI) + Bevacizumab as First Line Treatment of Patients With Metastatic Colorectal Cancer Not Previously Treated and With Three or More Circulating Tumoral Cells (VISNU-1)

Metastatic Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Hoffmann-La Roche

Completed

Safety and Efficacy Study of Gemcitabine-erlotinib Versus Gemcitabine-erlotinib-capecitabine in Patients With Metastatic Pancreatic Cancer (GECA)

Metastatic Pancreatic Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Hoffmann-La Roche

Completed

Safety and Efficacy Study to Compare Capecitabine + Bevacizumab Versus Capecitabine, Concomitantly With Radiotherapy as Neoadjuvant Treatment for Patients With Localized and Resectable Rectal Cancer (AVAXEL)

Rectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Hoffmann-La Roche

Completed

Selecting Treatment in Colorectal Cancer:Capecitabine or 5-fluorouracil Selection to be Combined With Oxaliplatin or Irinotecan as First-line Chemotherapy in Advanced Colorectal Cancer (SETICC)

Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Roche Pharma AG

Completed

Influence of BRAF and PIK3K Status on the Efficacy of 5-Fluorouracil/Leucovorin/Oxaliplatin (FOLFIRI) Plus Bevacizumab or Cetuximab in Patients With RAS Wild-type Metastatic Colorectal Carcinoma and < 3 Circulating Tumor Cells (CTC) (VISNU-2)

Colorectal Cancer Metastatic

Spain
Spanish Cooperative Group for the Treatment of...
Hoffmann-La Roche

Completed

Irinotecan, Capecitabine and Bevacizumab in Metastatic Colorectal Cancer Patients (AVAXIRI)

Metastatic Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Merck Sharp & Dohme LLC

Terminated

Phase II Study to Evaluate Safety and Efficacy of Cetuximab in Combination With XELOX for 12 Weeks Followed by Maintenance Treatment With Cetuximab Plus Capecitabine as First-line Treatment in Elderly Patients With Metastatic Colorectal Cancer.

Metastatic Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Sanofi; Hoffmann-La Roche

Completed

Efficacy and Safety Study of Combination Therapy With Docetaxel-oxaliplatin-capecitabine in Patients With Advanced Gastric Adenocarcinoma and Intermediate General Status

Gastric Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Sanofi; Roche Pharma AG

Completed

Study of Bevacizumab Alone or Combined With Capecitabine and Oxaliplatin as Support Therapy in Metastatic Colorectal Cancer Patients

Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy Study of Combination Therapy With Cetuximab and FOLFOX4 in Patients With Colorectal Cancer

Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Sanofi; Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Combination of Cetuximab and Chemotherapy as Neoadjuvant Therapy Followed Concomitant Chemoradiotherapy Plus Cetuximab in Locoregional Esophageal Carcinoma

Esophageal Carcinoma

Spain
Spanish Cooperative Group for the Treatment of...
Merck, S.L., Spain; Pierre Fabre Ibérica, S.A.

Not yet recruiting

Study to Evaluate the Efficacy and Safety of Cetuximab in Combination With Encorafenib Plus Binimetinib as Induction Treatment in BRAF V600E Mutated MSS Initially Resectable or Potentially Resectable Advanced Colorectal Cancer (CEBBRA)

Colorectal Cancer
European Organisation for Research and Treatment...
National Cancer Institute (NCI); Medical Research Council; NCIC Clinical Trials... and other collaborators

Completed

Cisplatin Plus Gemcitabine With or Without Paclitaxel in Treating Patients With Stage IV Urinary Tract Cancer

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter | Urethral Cancer

France, Spain, Canada, United States, Denmark, Poland, Belgium, Germany, Netherlands, Italy, United Kingdom, Austria, Australia, Hungary, Slovakia, Israel
European Organisation for Research and Treatment...
Federation Francophone de Cancerologie Digestive; Arbeitsgemeinschaft fur Internistische... and other collaborators

Completed

Celecoxib Combined With Fluorouracil and Leucovorin in Treating Patients With Resected Stage III Adenocarcinoma (Cancer) of the Colon

Colorectal Cancer

Netherlands, Belgium, Austria

3

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