Clinical Trials Sponsored by TIMI Study Group

Total 593 results

The TIMI Study Group

Completed

Prevention of Arteriovenous Thrombotic Events in Critically-Ill COVID-19 Patients Trial (COVID-PACT)

COVID-19 | Venous Thromboembolism | Arterial Thrombosis

United States
Amgen
TIMI Study Group

Completed

LAPLACE-TIMI 57: Low-density Lipoprotein Cholesterol (LDL-C) Assessment With PCSK9 monoclonaL Antibody Inhibition Combined With Statin thErapy (LAPLACE)

Hyperlipidemia

United States, Canada, Denmark, Czechia, Hungary
Pfizer
TIMI Study Group

Completed

A Dose-Ranging Study With Vupanorsen (TRANSLATE-TIMI 70)

Dyslipidemias | Hyperlipidemias | Hyperlipoproteinemias

United States, Canada, Poland
GlaxoSmithKline
The TIMI Study Group

Completed

The Stabilization Of pLaques usIng Darapladib-Thrombolysis In Myocardial Infarction 52 Trial (SOLID-TIMI 52)

Acute Coronary Syndrome

United States, France, Netherlands, Ukraine, Germany, Taiwan, Bulgaria, Hungary, Poland, Russian Federation, Argentina, Belgium, Peru, Philippines, Sweden, Thailand, Israel, Spain, Korea, Republic of, Australia, Czechia, Japan, New... and more
GlaxoSmithKline
The TIMI Study Group

Completed

A Phase 3 Clinical Outcomes Study to Compare the Incidence of Major Adverse Cardiovascular Events in Subjects Presenting With Acute Coronary Syndrome Treated With Losmapimod Compared to Placebo (LATITUDE-TIMI 60) (LATITUDE)

Acute Coronary Syndrome

United States, Australia, France, Spain, Taiwan, Estonia, Poland, Russian Federation, Belgium, Philippines, Sweden, Thailand, Germany, Israel, Bulgaria, Hong Kong, Netherlands, Norway, Slovakia, South Africa, Korea, Republic of, R... and more
Novartis
The TIMI Study Group

Completed

Efficacy and Safety of Aliskiren and Valsartan Versus Placebo in Patients Stabilized Following an Acute Coronary Syndrome

Myocardial Ischemia | Post Acute Coronary Syndrome

Germany, Spain, United States, Belgium, Canada, Czech Republic, Hungary, Netherlands, Poland, Russian Federation, Sweden
Gilead Sciences
The TIMI Study Group

Completed

Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST Elevation Acute Coronary Syndromes

Myocardial Ischemia

United States
ARCA Biopharma, Inc.
The TIMI Study Group

Completed

Anticoagulation With rNAPc2 to Eliminate MACE/TIMI 32

Coronary Disease

United States
Daiichi Sankyo, Inc.
The TIMI Study Group

Completed

Global Study to Assess the Safety and Effectiveness of Edoxaban (DU-176b) vs Standard Practice of Dosing With Warfarin in Patients With Atrial Fibrillation (EngageAFTIMI48)

Stroke | Embolism | Atrial Fibrillation

United States, Australia, France, Italy, Poland, Taiwan, Ukraine, United Kingdom, China, Belgium, Germany, Spain, Argentina, Colombia, Israel, Mexico, Portugal, Bulgaria, India, Romania, Russian Federation, Serbia, South Africa, Turkey, Korea, Republic of and more
The TIMI Study Group
Bristol-Myers Squibb; Sanofi

Completed

Escalating Clopidogrel by Involving a Genetic Strategy - Thrombolysis In Myocardial Infarction 56 (ELEVATE)

Myocardial Infarction | Percutaneous Coronary Intervention

United States
The TIMI Study Group
AstraZeneca; Worldwide Clinical Trials

Recruiting

Dapagliflozin and Effect on Cardiovascular Events in Acute Heart Failure -Thrombolysis in Myocardial Infarction 68 (DAPA ACT HF-TIMI 68)

Heart Failure | Acute Heart Failure

United States
AstraZeneca
Thrombolysis in Myocardial Infarction (TIMI) Study Group

Completed

Efficacy and Safety of MEDI6570 in Patients With a History of Myocardial Infarction (GOLDILOX)

Coronary Heart Disease (CHD)

United States, Italy, Netherlands, Spain, Japan, Czechia, Hungary, Australia, Poland, Canada, United Kingdom
University of Oxford
Novartis Pharmaceuticals; The TIMI Study Group

Active, not recruiting

A Randomized Trial Assessing the Effects of Inclisiran on Clinical Outcomes Among People With Cardiovascular Disease (ORION-4)

Atherosclerotic Cardiovascular Disease

United Kingdom, United States
MedImmune LLC
Thrombolysis in Myocardial Infarction (TIMI) Study Group

Completed

A Study to Evaluate the Safety and Efficacy of MEDI6012 in Acute ST Elevation Myocardial Infarction (REAL-TIMI 63B)

ST Elevation Myocardial Infarction

Netherlands, United Kingdom, Brazil, Spain, Slovakia, Israel, Czechia, Hungary, Poland, Russian Federation
Eli Lilly and Company
Daiichi Sankyo, Inc.; The TIMI Study Group

Completed

Trial in Subjects Undergoing Cardiac Catheterization With Planned Percutaneous Coronary Intervention With Stenting (PRINCIPLE)

Coronary Artery Disease

France, United States, Israel, Germany
Anthos Therapeutics, Inc.
Laboratory Corporation of America; The TIMI Study Group

Active, not recruiting

Safety and Tolerability of Abelacimab (MAA868) vs. Rivaroxaban in Patients With Atrial Fibrillation (AZALEA-TIMI 71)

Stroke | Atrial Fibrillation (AF)

United States, Canada, Czechia, Hungary, Korea, Republic of, Poland, Taiwan
AstraZeneca
Bristol-Myers Squibb; Hadassah Medical Organization; The TIMI Study Group

Completed

Multicenter Trial to Evaluate the Effect of Dapagliflozin on the Incidence of Cardiovascular Events (DECLARE-TIMI58)

Diabetes Mellitus, Non-Insulin-Dependent | High Risk for Cardiovascular Event

United States, Canada, France, Italy, Netherlands, Spain, Belgium, Thailand, Vietnam, Bulgaria, Korea, Republic of, Brazil, Philippines, Russian Federation, Turkey, Taiwan, Australia, Israel, South Africa, Germany, Japan, Czechia, H... and more
Merck Sharp & Dohme LLC
The Thrombolysis in Myocardial Infarction Study (TIMI) Group

Completed

Trial to Assess the Effects of Vorapaxar (SCH 530348; MK-5348) in Preventing Heart Attack and Stroke in Patients With Atherosclerosis (TRA 2°P - TIMI 50) (P04737)

Myocardial Infarction | Ischemia | Peripheral Arterial Disease | Atherosclerosis | Cerebrovascular Accident
Danish Study Group

Not yet recruiting

Coronary Artery Bypass Grafts or Percutaneous Coronary Intervention for High Risk Patients

LV Dysfunction | IHD

Denmark
SURPRISE Study Group

Completed

Success of Tocilizumab in RA Patients With Remission Induction and Sustained Efficacy After Discontinuation (SURPRISE)

Rheumatoid Arthritis

Japan
AGO Study Group

Completed

Liposomal Doxorubicin and Carboplatin in Treating Patients With Gynecologic Cancer

Sarcoma | Cervical Cancer | Ovarian Cancer | Fallopian Tube Cancer | Endometrial Cancer

Germany
AGO Study Group

Completed

Randomized, Multicenter, 2-Dose Level. Open-Label, Phase IIa Study With the Intraperitoneally Infused Trifunctional Bispecific Antibody Removab(TM) (Anti-EpCAM x Anti-CD3) to Select the Better Dose Level in Platinum Refractory Epithelial Ovarian Cancer Patients

Fallopian Tube Neoplasms | Peritoneal Neoplasms | Ovarian Cancer

Germany
Tokyo Study Group

Completed

Intervention to Preserve Beta-Cell Function in GAD Ab-Positive Diabetes

GAD Ab Positive Clinically Type 2 Diabetic Patients

Japan
AGO Study Group

Terminated

Reinduction Chemotherapy Containing Carboplatin and Paclitaxel With or Without Epoetin Alpha in Recurrent Platinum Sensitive Ovarian Cancer, Cancer of the Fallopian Tube or Peritoneum

Anemia | Epithelial Ovarian Cancer, Fallopian Tube or Peritoneum | Platinum Sensitve Relapse

Germany
Ataxia Study Group

Recruiting

The EUROSCA Natural History Study (EUROSCA-NHS)

Spinocerebellar Ataxia

Austria, Belgium, France, Germany, Hungary, Italy, Netherlands, Poland, Spain, United Kingdom
Huntington Study Group

Completed

Making HD Voices Heard

Huntington Disease

United States
Huntington Study Group

Completed

Development of the Virtual Unified Huntington's Disease Rating Scale (vUHDRS)

Huntington Disease

United States
AGO Study Group

Active, not recruiting

Trial on Radical Upfront Surgery in Advanced Ovarian Cancer (TRUST)

Ovarian Cancer

United States, France, Germany, Austria, Sweden, Denmark, Italy, United Kingdom
AGO Study Group

Completed

Efficacy,Tolerability,Safety of Temsirolimus in Women With Platinum-refractory Ovarian Carcinoma or Advanced Endometrial Carcinoma

Ovarian Diseases | Ovarian Neoplasms | Endometrial Neoplasms | Genital Diseases, Female

Germany
AGO Study Group

Completed

Paclitaxel Plus Carboplatin With or Without Topotecan in Treating Patients With Stage IIB, Stage III, or Stage IV Ovarian Epithelial Cancer

Ovarian Cancer | Fallopian Tube Cancer

Germany
AGO Study Group

Completed

Comparison of Paclitaxel/Carboplatin and Lonafarnib to Paclitaxel/Carboplatin for First-line Treatment of Ovarian Cancer

Epithelial Ovarian Cancer

Germany
AGO Study Group

Completed

Paclitaxel, Carboplatin, and Topotecan in Patients With Ovarian Cancer

Ovarian Cancer

Germany
Famirea Study Group

Terminated

A Communication Strategy for Families of Patients Dying in the ICU

Family of Dying Patient in the ICU
ALDUS Study Group

Enrolling by invitation

Surveillance Study for HCC by Combining Biomarkers With Imaging (ALDUS) (ALDUS)

Liver Cirrhosis

Japan
AGO Study Group

Completed

Combination Chemotherapy in Treating Patients With Ovarian Epithelial, Fallopian Tube, or Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer

Germany
Bistro Study Group

Completed

Quality of Chest Compressions After a Night Shift (WeCAN)

Cardiac Arrest

France
AGO Study Group

Completed

A Phase II Study of ZD1839 and Tamoxifen in Patients With Epithelial Ovarian Carcinoma, Cancer of the Fallopian Tube or the Peritoneum Refractory to Platinum- and Taxane-based Therapy

Ovarian Cancer | Peritoneal Cancer | Cancer of the Fallopian Tube

Germany
NORDynamIC Study Group

Completed

Multicenter Study Evaluating 12 Versus 24 Weeks Therapy With Peginterferon and Ribavirin for Hepatitis C Virus (HCV) Genotype 2 or 3

Hepatitis C Virus

Sweden
AGO Study Group

Completed

Gemcitabine Plus Carboplatin Versus Carboplatin Monotherapy in Patients With Advanced Ovarian Cancer

Ovarian Cancer
AGO Study Group

Completed

Use of ACA 125 in Patients With Ovarian Cancer: Safety and Immune Response

Fallopian Tube Neoplasms | Peritoneal Neoplasms | Ovarian Cancer

Germany
Czech Lymphoma Study Group

Not yet recruiting

Study of PV in Combination With Bendamustine and Rituximab for Patients With R/R MCL (CLSGMCLPOLA)

Lymphoma, Mantle-Cell

Czechia
German CLL Study Group

Active, not recruiting

Efficacy and Safety of Zanubrutinib Plus Tislelizumab for Treatment of Patients With Richter Transformation (CLL-RT1)

Richter Transformation

Denmark, Germany, Austria
West German Study Group

Active, not recruiting

Adjuvant Dynamic Marker-Adjusted Personalized Therapy Trial Optimizing Risk Assessment and Therapy Response Prediction in Early Breast Cancer (ADAPT)

Breast Cancer

Germany
West German Study Group

Active, not recruiting

ADAPT - Adjuvant Dynamic Marker-Adjusted Personalized Therapy Trial Optimizing Risk Assessment and Therapy Response Prediction in Early Breast Cancer (ADAPT)

Breast Cancer

Germany
German CLL Study Group

Completed

Fludarabine or Observation in Treating Patients With Stage 0, Stage I, or Stage II Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

Germany, Austria
German CLL Study Group

Completed

Alemtuzumab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

Germany
German CLL Study Group

Completed

Fludarabine With or Without Cyclophosphamide in Treating Patients With Advanced Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

Germany, Austria
German CLL Study Group

Completed

Combination Chemotherapy Followed By Alemtuzumab in Treating Patients With Chronic Lymphocytic Leukemia or Prolymphocytic Leukemia

Prolymphocytic Leukemia

Germany, Austria
German CLL Study Group

Completed

Combination Chemotherapy, Total-Body Irradiation, and Alemtuzumab in Treating Patients Undergoing an Autologous Stem Cell Transplant for Stage I, Stage II, Stage III, or Stage IV Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

Germany
Bergen Orthopedic Study Group

Completed

Results at 10 to 14 Years After Microfracture in the Knee

Articular Chondral Defect

Norway

Clinical Trials Sponsored by TIMI Study Group

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Congo, DR of

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations