Clinical Trials Sponsored by TRB Chemedica

Total 329 results

Global Alliance for TB Drug Development

Completed

Evaluation of the Pharmacokinetic Interaction Between PA-824 and Midazolam

Tuberculosis

United States
Global Alliance for TB Drug Development

Completed

A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TBA-354 in Healthy Adult Subjects

Tuberculosis

United States
Global Alliance for TB Drug Development

Completed

A Phase 2 Trial to Evaluate the Efficacy and Safety of Linezolid in Tuberculosis Patients. (LIN-CL001)

Pulmonary Tuberculosis

South Africa
Global Alliance for TB Drug Development

Completed

PA-824-CL-007: Phase IIa Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis

Pulmonary Tuberculosis

South Africa
Ilya Sivokozov

Recruiting

A Trial of Radial EBUS Versus VBN for the Peripheral Pulmonary Lesions

Pneumonia | Lung Cancer | Tuberculosis

Russian Federation
Global Alliance for TB Drug Development

Completed

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis (CL-010)

Pulmonary Tuberculosis
Global Alliance for TB Drug Development

Terminated

A Multiple Ascending Dose Study With a Dose Formulation Comparison Cohort to Evaluate the Safety, Tolerability, and Pharmacokinetics of TBA-354 in Healthy Adult Subjects

Tuberculosis
Global Alliance for TB Drug Development

Completed

PK Interaction Between Rifapentine or Rifampicin and a Single Dose of TMC207 in Healthy Subjects (TMC207-CL002)

Tuberculosis

United States
Global Alliance for TB Drug Development

Completed

A Phase 2 to Evaluate the Efficacy, Safety and Tolerability of Combinations of Bedaquiline, Moxifloxacin, PA-824 and Pyrazinamide in Adult Subjects With Drug-Sensitive or Multi Drug-Resistant Pulmonary Tuberculosis. (NC-005)

Tuberculosis

Tanzania, South Africa, Uganda
Global Alliance for TB Drug Development

Completed

Shortening Treatment by Advancing Novel Drugs (STAND)

Tuberculosis, Pulmonary, Drug Sensitive | Tuberculosis, Pulmonary, Multi Drug-resistant

South Africa, Zambia, Georgia, Philippines, Kenya, Malaysia, Tanzania, Uganda
Global Alliance for TB Drug Development

Completed

A Study of the Safety, Tolerability, and Absorption, Metabolism, and Excretion of PA-824 in Healthy Adult Male Subjects. (CL-004)

Tuberculosis

United States
Global Alliance for TB Drug Development

Completed

Evaluation of 8 Weeks of Treatment With the Combination of Moxifloxacin, PA-824 and Pyrazinamide in Patients With Drug Sensitive and Multi Drug-Resistant Pulmonary Tuberculosis (TB) (NC-002)

Pulmonary Tuberculosis

Tanzania, South Africa
Global Alliance for TB Drug Development

Completed

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Sutezolid

Tuberculosis | Tuberculosis, Pulmonary

United States
Global Alliance for TB Drug Development

Completed

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis (TMC207-CL001)

Pulmonary Tuberculosis

South Africa
Global Alliance for TB Drug Development

Completed

Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects (CL-003)

Tuberculosis

United States
Kaohsiung Medical University Chung-Ho Memorial...
Tri-Service General Hospital

Recruiting

Impact of Propofol-Based Total Intravenous Anesthesia Versus Anesthesia With Sevoflurane on Long-term Outcomes With Patients Undergoing Elective Excision of Primary Liver Tumors

Hepatocellular Carcinoma

Taiwan
University of South Florida
Florida High Tech Corridor Council; TRS, Inc.

Completed

Functional Performance of Voluntary Opening and Closing Body Powered Prostheses

Upper Limb Amputation

United States
Global Alliance for TB Drug Development

Completed

Trial to Evaluate the Efficacy, Safety and Tolerability of BPaMZ in Drug-Sensitive (DS-TB) Adult Patients and Drug-Resistant (DR-TB) Adult Patients

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Tuberculosis, MDR | Drug-Resistant Tuberculosis

Tanzania, Georgia, Russian Federation, Brazil, Malaysia, Philippines, South Africa, Uganda
Global Alliance for TB Drug Development

Completed

Study to Evaluate Safety, Tolerability, and the PK Profile of TBI-223 in Healthy Subjects

Tuberculosis | Tuberculosis, Pulmonary

United States
Global Alliance for TB Drug Development

Completed

A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics of TBI-223 in Healthy Adults

Tuberculosis | Tuberculosis, Pulmonary

United States
Global Alliance for TB Drug Development

Completed

A Study in Two Panels of Healthy Adult Participants to Assess Single-Dose Immediate-Release and Single-Dose Dispersible Formulations of Pretomanid

Multi-drug Resistant Tuberculosis

United States
Global Alliance for TB Drug Development

Completed

Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects (CL-009) (CL-009)

Tuberculosis

United States
Global Alliance for TB Drug Development

Completed

A Phase 1 Study to Evaluate Safety, Tolerability, PK, and PK Interactions of TBA-7371

Tuberculosis | Tuberculosis, Pulmonary

United States
Global Alliance for TB Drug Development

Completed

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With(J-M-Pa-Z) (NC-001)

Pulmonary Tuberculosis

South Africa
Global Alliance for TB Drug Development

Completed

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With Clofazimine (C)-TMC207 (J)-PA-824 (Pa)-Pyrazinamide (Z) (NC-003)

Pulmonary Tuberculosis

South Africa
Mackay Medical College
Tri-Service General Hospital; National Defense Medical Center, Taiwan

Completed

Effects of Cognitive-Oriented Intervention on Major Depressive Disorder

Mental Health Issue
National Taipei University of Nursing and Health...
Tri-Service General Hospital

Completed

Decision Support for the Renal Replacement Therapy With End-stage Renal Disease

Chronic Renal Disease

Taiwan
National Taiwan University Hospital
Chang Gung Memorial Hospital; Tri-Service General Hospital

Unknown

Evaluation of Collagen Dermal Filler With Lidocaine for the Correction of Nasolabial Folds

Nasolabial Fold

Taiwan
NPO International TRI Network
Duke Clinical Research Institute; European Cardiovascular Research Center

Unknown

Radial Artery Patency and Bleeding, Efficacy, Adverse evenT Trial (RAPandBEAT)

Percutaneous Coronary Intervention
National Taipei University of Nursing and Health...
Tri-Service General Hospital

Not yet recruiting

Study on the Effect of Incentive Spirometer-based Respiratory Training on the Long COVID-19

Hypertension | Diabetes | Long COVID | Cardiac Disease | COVID-19 Pandemic
National Defense Medical Center, Taiwan
Tri-Service General Hospital; Cardinal Tien Hospital

Completed

GSP as an Novel Indicator for Residual Liver Function in Patients With Fatty Liver (GSP)

Galactose Single Point (GSP), Residual Liver Function
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator...

Not yet recruiting

Pharmacogenomics IND EXEMPT SNP Clinical Study - Alectinib and Single Nucleotide Polymorphisms (Drugs-SNPs)

Non-small Cell Lung Cancer

United States
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator...

Active, not recruiting

Early Phase Clinical Trial About Therapeutic Biological Product Mix for Treating HPV (9vHPV-BCG)

HPV Infection

United States
National Taiwan Normal University
Division of Endocrinology and Metabolism, Tri-Service General Hospital

Completed

Effects of Breaking Sitting on Human Behaviour and Metabolic Health

Cognition | Energy Balance | Metabolic Health | Physical Activity Level

Taiwan
IRB of NTUH Hsin-Chu Branch

Completed

Needlescopic-assisted Uniportal vs Uniportal VATS (UNeed)

Lung Cancer | Lung Cancer Metastatic | Mediastinal Tumor | Nodule Solitary Pulmonary | Bullous Disease Lung

Taiwan
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator...

Not yet recruiting

Pharmacogenomics IND EXEMPT SNP Clinical Study - Crizotinib and Single Nucleotide Polymorphisms (Drugs-SNPs)

Non-Small Cell Lung Cancer

United States
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator...

Active, not recruiting

Pharmacogenomics IND EXEMPT SNP Clinical Study - Abiraterone and Single Nucleotide Polymorphisms (Drugs-SNPs)

Prostate Cancer

United States
On-X Life Technologies, Inc.
Clinipace Worldwide; Avania; Acelis Connected Health; WCG IRB

Active, not recruiting

Randomized On-X Anticoagulation Trial (PROACT)

Heart Valve Disease

United States, Canada
IRB of NTUH Hsin-Chu Branch

Unknown

Difference of Information Gain Between Video-base and Doctor Interview After Preanesthetic Visit

Anesthesia
National Taiwan University Hospital
Taipei Veterans General Hospital, Taiwan; Tri-Service General Hospital

Completed

Axitinib as Second-line Treatment for Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma

Taiwan
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator...
UnitedHealthcare

Active, not recruiting

Pharmacogenomics IND EXEMPT SNP Clinical Study - Etoposide and Single Nucleotide Polymorphisms (Drugs-SNPs)

Small Cell Lung Cancer

United States
University of Arkansas
Coalition for a Tobacco Free Arkansas; Tri-County Rural Health Network

Completed

Reducing Tobacco Exposures Among African American Women and Children (FRESH)

Tobacco Use | Second Hand Tobacco Smoke

United States
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator...
PPD

Active, not recruiting

Proof-of-Concept Clinical Pharmacology Trial for COVID-19 Antigen Presentation Therapeutic Biologics (COV19-APTP-B)

Covid19

United States
Ivy Life Sciences, Co., Ltd
Taipei Veterans General Hospital, Taiwan; Tri-Service General Hospital

Completed

A Study to Evaluate the Safety and Efficacy of Ex Vivo Expanded Autologous Immune Killer Cells (IKC) in Stage IV Non-small Cell Lung Cancer (NSCLC) in Patients Who Failed Chemotherapy or Target Therapy (IVY03)

Non-small Cell Lung Cancer (NSCLC) Stage IV

Taiwan
Stemedica Cell Technologies, Inc.
University of California, San Diego; Mercy Gilbert Medical Center at AZ; Chandler... and other collaborators

Completed

A Study of Allogeneic Mesenchymal Bone Marrow Cells in Subjects With Ischemic Stroke

Ischemic Stroke

United States
Global Alliance for TB Drug Development
QPS Holdings LLC

Completed

Evaluation of the Safety, Tolerability, PK of TBAJ-587 in Healthy Adults

Tuberculosis

Netherlands
Germans Trias i Pujol Hospital
CIBERES CRP-TB program

Unknown

Study of Latent Tuberculosis Infection (LTBI) by High Resolution Scanner (GRANLATHU)

Tuberculosis

Spain
National Health Research Institutes, Taiwan
Tri-Service General Hospital; Academia Sinica, Taiwan; Fu Jen Catholic University

Completed

Vegetable Signature From Human Metabolomics Responses

Vegetable Signature Documentation With Metabolomic Technique
National Institute of Allergy and Infectious Diseases...
TB Alliance

Not yet recruiting

Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis (RAD-TB)

Pulmonary Tuberculosis

Botswana, Brazil, Haiti, India, Kenya, Malawi, Mexico, Peru, Philippines, South Africa, Thailand, Uganda, Zimbabwe
Desmond Tutu TB Centre
University of Stellenbosch; UNITAID; Chiang Mai University

Recruiting

Pharmacokinetics and Safety of DolutegravIr in Neonate (PETITE-DTG)

Hiv

South Africa

Clinical Trials Sponsored by TRB Chemedica

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Indonesia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations