Clinical Trials Sponsored by TenNor Therapeutics Limited

Total 135 results

TenNor Therapeutics Limited

Completed

TNP-2092 to Treat Acute Bacterial Skin and Skin Structure Infection (P2_ABSSSI)

Gram-Positive Bacterial Infections | Skin and Subcutaneous Tissue Bacterial Infections

United States
TenNor Therapeutics Limited

Completed

Tissue Distribution, Pharmacokinetics, Safety, and Tolerability After a Single Dose of TNP-2092 in Participants Undergoing Primary Total Hip or Knee Arthroplasty

Prosthetic Joint Infection

United States
TenNor Therapeutics Limited

Completed

Absorption, Metabolism, and Excretion Study of [14C]-TNP-2092

Healthy

United States
TenNor Therapeutics (Suzhou) Limited

Completed

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of TNP-2198 Capsules in Asymptomatic Participants With Helicobacter Pylori Infection

Helicobacter Pylori Infection

China
TenNor Therapeutics (Suzhou) Limited

Completed

Efficacy and Safety of Rifasutenizol (TNP 2198) in Participants With H. Pylori Infection

H.Pylori Infection

China
TenNor Therapeutics (Suzhou) Limited

Completed

A Phase 1, Single-center, Double-blind, Placebo-controlled Study of TNP-2092 Capsules, and the Food Effect Study After Single-dose Oral Administration of TNP-2092 Capsules

Hyperammonemia

China
TenNor Therapeutics (Suzhou) Limited

Completed

Efficacy and Safety After Multiple Doses of TNP-2198 Capsules, Rabeprazole Sodium Enteric-coated Tablets and Amoxicillin Capsules in Helicobacter Pylori Infected-positive Participants

Helicobacter Pylori Infection

China
TenNor Therapeutics (Suzhou) Limited

Completed

A Study to Evaluate Preliminary Helicobacter Pylori Eradication After Multiple Doses of TNP-2198 Capsules Combined With Rabeprazole Sodium Enteric-coated Tablets, or Rabeprazole Sodium Enteric-coated Tablets and Amoxicillin Capsules

Helicobacter Pylori Infection

China
TenNor Therapeutics (Suzhou) Limited

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Food Effect of TNP-2198 Capsules After Single Oral Dose in Healthy Participants

Helicobacter Pylori Infection

China
TenNor Therapeutics (Suzhou) Limited

Completed

Human Mass Balance and Biotransformation Study of [14C]TNP-2198

Helicobacter Pylori Infection

China
TenNor Therapeutics (Suzhou) Limited

Completed

Safety, Tolerability, Pharmacokinetic Characteristics and Preliminary Efficacy of TNP-2092 Capsules in Liver Cirrhosis Patients With Hyperammonemia

Hyperammonemia

China
TenNor Therapeutics Inc.

Completed

The Safety and Tolerability, Pharmacokinetics of TNP-2092 Capsules in Combination With Rabeprazole Sodium Enteric-coated Tablets

Helicobacter Pylori Infection

China
TenNor Therapeutics Inc.

Completed

A Phase 1, Multiple Oral Administrations of TNP-2092 Capsules in Asymptomatic Healthy People With Helicobacter Pylori Infection

Helicobacter Pylori Infection
Heptares Therapeutics Limited
P1vital Limited

Completed

Phase 1 Study Investigating Effects of HTL0009936 on Cognition and BOLD fMRI Signals in Healthy Elderly Subjects

Alzheimer's Disease

United Kingdom
Autifony Therapeutics Limited

Recruiting

Safety, Blood Levels and Effects of AUT00201 in Patients With MEAK (AUT022201)

Myoclonus Epilepsies, Progressive

United States
Amplia Therapeutics Limited

Recruiting

ACCENT: AMP945 in Combination With Nab-paclitaxel and Gemcitabine for Treatment of Pancreatic Cancer

Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma | PDAC

Australia, Korea, Republic of
Quell Therapeutics Limited

Recruiting

Prospective Study of White Blood Cells

Autoimmune Diseases | Inflammation | Rejection; Transplant, Liver

United Kingdom
Heptares Therapeutics Limited

Completed

Comparison of Blood Levels of HTL0016878 From an Oral Capsule and an Oral Solution

Healthy Subjects

United Kingdom
Heptares Therapeutics Limited

Completed

Measurement of HTL0016878 in Cerebrospinal Fluid

Healthy Subjects

United Kingdom
Heptares Therapeutics Limited

Completed

Pharmacokinetics of Oral Capsule in Healthy Japanese vs. Caucasian Subjects (HTL0018318)

Pharmacokinetics | Safety Issues

United Kingdom
Autifony Therapeutics Limited

Completed

Evaluating Possible Improvement in Speech and Hearing Tests After 28 Days of Dosing of the Study Drug AUT00063 Compared to Placebo (QuicKfire)

Hearing Loss | Hearing Impairment

United Kingdom
Heptares Therapeutics Limited

Completed

Relative Bioavailability of HTL0018318 Oral Aqueous Solution Versus Capsules

Bioavailability and Pharmacokinetics

United Kingdom
SynOx Therapeutics Limited

Not yet recruiting

Study of Emactuzumab for Tenosynovial Giant Cell Tumor (TGCT) (TANGENT)

TGCT

United States
Carrick Therapeutics Limited

Completed

Modular Study to Evaluate CT7001 Alone in Cancer Patients With Advanced Malignancies

Advanced Solid Malignancies

United States, United Kingdom
Heptares Therapeutics Limited

Terminated

A Study in Healthy Subjects to Assess the Safety, Tolerability and Pharmacokinetics of HTL0022562

Healthy

United Kingdom
Karus Therapeutics Limited

Completed

The Safety, Pharmacokinetic and Pharmacodynamic Effect of KA2237 (PI3 Kinase p110β/δ Inhibitor) In B Cell Lymphoma

Lymphoma, B Cell

United States
Autifony Therapeutics Limited

Completed

Efficacy and Safety of AUT00063 Versus Placebo in Age-Related Hearing Loss (CLARITY-1)

Age-Related Hearing Loss

United States
Heptares Therapeutics Limited

Completed

Phase I, Healthy Subject, Safety, Tolerability and Pharmacokinetic Study of an M1 Agonist to Treat Cognitive Impairment

Alzheimer's Disease

United Kingdom
Cynata Therapeutics Limited

Recruiting

A Study of CYP-001 in Combination With Corticosteroids in Adults With High-risk aGvHD

Graft Versus Host Disease, Acute

United States, Australia, Turkey
Quell Therapeutics Limited

Recruiting

Safety and Clinical Activity of QEL-001 in A2-mismatch Liver Transplant Patients (LIBERATE)

Liver Diseases | Liver Failure | Rejection; Transplant, Liver

Belgium, United Kingdom, Spain
Cynata Therapeutics Limited

Recruiting

Safety, Tolerability and Efficacy of CYP-006TK in Adults With Diabetic Foot Ulcers

Diabetic Foot Ulcer | Cutaneous Ulcer

Australia
Kazia Therapeutics Limited

Recruiting

Safety, Tolerability, and Pharmacokinetics of EVT801 in Patients With Advanced Solid Tumours

Solid Tumor, Adult

France
Kazia Therapeutics Limited

Completed

Safety, Pharmacokinetics and Efficacy of Paxalisib (GDC-0084) in Newly-diagnosed Glioblastoma

Glioblastoma, Adult

United States
Everstar Therapeutics Limited

Active, not recruiting

A Phase 3 Study of Etrasimod in Subjects With Moderately to Severely Active Ulcerative Colitis

Moderately to Severely Active Ulcerative Colitis

China
GammaDelta Therapeutics Limited

Terminated

Study of GDX012 in Patients With MRD Positive AML

Acute Myeloid Leukemia

United States
Heptares Therapeutics Limited

Completed

Study to Investigate the Receptor Occupancy of HTL0014242 Using [18F] FPEB in Healthy Male Subjects

Healthy

United Kingdom
Autifony Therapeutics Limited

Completed

Safety, Blood Levels and Effects of AUT00201

Healthy Volunteer

United Kingdom
Heptares Therapeutics Limited

Completed

A Study in Healthy Subjects to Assess the Safety, Tolerability, PK and PD of HTL0030310

Healthy

United Kingdom
Karus Therapeutics Limited

Completed

Safety,Tolerability and MTD KA2507 (HDAC6 Inhibitor) in Patients With Solid Tumours (HDAC6i)

Solid Tumor, Adult

United States
Cynata Therapeutics Limited

Completed

A Study of CYP-001 for the Treatment of Steroid-Resistant Acute Graft Versus Host Disease

Graft vs Host Disease

Australia, United Kingdom
Kazia Therapeutics Limited

Completed

Phase I Study of Cantrixil in Patients With Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer.

Ovarian Neoplasms | Fallopian Tube Neoplasms | Peritoneal Neoplasms

United States, Australia
Autifony Therapeutics Limited

Completed

Safety, Blood Levels and Effects of AUT00206

Schizophrenia

United Kingdom
KGK Science Inc.
Gencor Pacific Limited

Completed

A Study Investigating the Effects of Activamp on Body Weight, Fat Loss, and Metabolic Markers in Healthy Overweight Participants (14AWHG)

Body Weight

Canada
Visirna Therapeutics HK Limited

Not yet recruiting

A Phase 3 Study of VSA001 in Chinese Adults With Familial Chylomicronemia Syndrome

Familial Chylomicronemia Syndrome
Visirna Therapeutics HK Limited

Not yet recruiting

A VSA003 Phase 1 Study in Chinese Adult Healthy Volunteers

Dyslipidemias | Hypertriglyceridemia | Familial Hypercholesterolemia
Achilles Therapeutics UK Limited

Recruiting

ATL001 in Patients With Advanced Unresectable or Metastatic NSCLC

Advanced Non Small Cell Lung Cancer

United States, Germany, France, Spain, United Kingdom
Achilles Therapeutics UK Limited

Recruiting

Prospective Tissue Collection Research Protocol

Solid Tumor

Spain, United Kingdom, United States
Achilles Therapeutics UK Limited

Terminated

Long-Term Follow-Up Study of Patients Receiving ATL001

Melanoma | Advanced Non Small Cell Lung Cancer

United Kingdom
Iterum Therapeutics, International Limited

Available

Expanded Access Use of Sulopenem Etzadroxil/Probenecid for Complicated Urinary Tract Infection

Acute Pyelonephritis | Complicated Urinary Tract Infection
Heptares Therapeutics Limited
Covance

Completed

Phase 1, Healthy Subject, Safety, Tolerability and Pharmacokinetic Study of mGlu5 NAM HTL0014242

Healthy

United Kingdom

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