Clinical Trials Sponsored by UNC Lineberger Comprehensive Cancer Center

Total 5619 results

Case Comprehensive Cancer Center

Completed

Paclitaxel Plus Radiation Therapy in Treating Women With Stage II or Stage III Breast Cancer

Breast Cancer

United States
Case Comprehensive Cancer Center

Active, not recruiting

CPX-351 as a Novel Approach for the Treatment of Older Patients With AML and MDS

Myelodysplastic Syndromes | Refractory Acute Myeloid Leukemia | Relapsed Acute Myelomonocytic Leukemia

United States
Case Comprehensive Cancer Center

Active, not recruiting

Leveraging ctDNA Analysis to Improve Early Detection of Cancer Recurrence in the High-Risk Melanoma Setting

Stage III Melanoma | Stage IV Cutaneous Melanoma

United States
Case Comprehensive Cancer Center

Withdrawn

Captopril Use on the Degree of Marrow Fibrosis in Bone Marrow Fibrosis/Myeloproliferative Neoplasms

Myeloproliferative Neoplasm | Bone Marrow Fibrosis

United States
Case Comprehensive Cancer Center

Suspended

Integrated Imaging System for In Vivo Visualization of Free Flap Perfusion Using Indocyanine Dye

Breast Reconstruction

United States
Case Comprehensive Cancer Center

Completed

Carboplatin, Nab-Paclitaxel and Pembrolizumab for Metastatic Triple-Negative Breast Cancer

Metastatic Triple Negative Breast Cancer

United States
Case Comprehensive Cancer Center

Active, not recruiting

Improving Understanding of Brain Tumors Through Preservation of Biologically Active Brain Tissue

Glioblastoma

United States
Case Comprehensive Cancer Center

Completed

Tac, Mini-MTX, MMF Versus Tac, MTX for GVHD Prevention

Acute Myeloid Leukemia | Multiple Myeloma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Chronic Myelogenous Leukemia | Myeloproliferative Neoplasm | Acute Biphenotypic Leukemia | Hodgkins Disease

United States
Case Comprehensive Cancer Center

Withdrawn

Dendritic Cell DKK1 Vaccine for Monoclonal Gammopathy and Stable or Smoldering Myeloma

Myeloma | Smoldering Myeloma | Monoclonal Gammopathy

United States
Case Comprehensive Cancer Center

Completed

Axitinib Given on an Individualized Schedule for Metastatic Renal Cell Cancer

Metastatic Renal Cell Cancer

United States
Case Comprehensive Cancer Center

Withdrawn

Prepectoral vs Partial Subpectoral Two-Stage Implant-Based Breast Reconstruction

Breast Reconstruction Following Mastectomy

United States
Jonsson Comprehensive Cancer Center

Completed

68Ga-PSMA-11 PET/CT in Imaging Patients With Intermediate or High Risk Prostate Cancer Before Surgery

Prostate Adenocarcinoma | Stage IV Prostate Cancer AJCC v7 | Stage III Prostate Cancer AJCC v7 | Stage IIB Prostate Cancer AJCC v7

United States
Case Comprehensive Cancer Center

Withdrawn

Correlation of Imaging Findings With Clinical Findings and Patient Outcomes in Prostate Cancer

Prostate Cancer
Case Comprehensive Cancer Center

Completed

Hematopoietic Stem Cell Transplant for Sickle Cell Disease

Sickle Cell Disease | Sickle Cell Anemia | SCD

United States
Case Comprehensive Cancer Center

Completed

Prehabilitation in Pancreatic Surgery

Pancreatic Resection | Preoperative Frailty

United States
Jonsson Comprehensive Cancer Center

Terminated

Anti-tumor Immune Response in Patients With Cancer Undergoing Radiation Therapy

Malignant Neoplasm

United States
Case Comprehensive Cancer Center

Completed

Assessment of Candidate Protein Expression in Breast Cancer Specimens

Breast Cancer

United States
Case Comprehensive Cancer Center

Completed

Assessment of Novel MRI Quantification Free Breathing Technique in Evaluation of Liver Lesions

Hepatocellular Carcinoma

United States
Case Comprehensive Cancer Center

Terminated

Weight-based Dosing for Dense Weekly Paclitaxel and Carboplatin in Overweight Patients w/ Body Surface Area (BSA) > 2.0

Gynecologic Malignancies

United States
Case Comprehensive Cancer Center

Terminated

Adolescent and Young Adult Survivor Transition (AYAST)

Adolescent and Young Adult Cancer

United States
Case Comprehensive Cancer Center

Completed

Temporally Feathered Radiation Therapy (TFRT) for Head and Neck Squamous Cell Carcinoma

Head and Neck Cancer

United States
Case Comprehensive Cancer Center

Completed

Efficacy of Digital Breast Tomosynthesis + Standard 2- Dimensional Mammography in Breast Cancer

Breast Cancer

United States
Case Comprehensive Cancer Center

Completed

Comparison of Yttrium-90 Absorbed Doses Using PET/CT Versus PET/MR Imaging for Hepatic Malignancies

Hepatic Malignancies

United States
Case Comprehensive Cancer Center

Completed

Apalutamide and Leuprolide in Intermediate and High-risk Prostate Cancer

Prostate Cancer

United States
Jonsson Comprehensive Cancer Center

Terminated

Quantifying Oxygen Utilization of Tumors Using Oxygen-Enhanced Molecular MRI

Malignant Brain Neoplasm

United States
Case Comprehensive Cancer Center

Withdrawn

Fluciclovine (Axumin) PET/CT vs. NaF PET/CT in Prostate Cancer Osseous Metastatic Disease

Malignant Neoplasm of Prostate

United States
Case Comprehensive Cancer Center

Completed

Improved Intra-operative Safety From Optimal Selection of Anti-slip Surface

Laparoscopic Surgery | Vaginal Surgery

United States
Case Comprehensive Cancer Center

Completed

Debulking Surgery in Ovarian Cancer (MIID-SOC)

Malignant Neoplasm of Ovary | Malignant Neoplasm of Fallopian Tube | Malignant Neoplasm of Peritoneum

United States
Case Comprehensive Cancer Center

Active, not recruiting

Eltrombopag Olamine in Improving Platelet Recovery in Older Patients With Acute Myeloid Leukemia Undergoing Chemotherapy

Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic... and other conditions

United States
Case Comprehensive Cancer Center

Completed

DRIHNC - Dehydration Reduction in Head & Neck Cancer

Esophageal Cancer | Dehydration | Head & Neck Cancer

United States
Jonsson Comprehensive Cancer Center

Approved for marketing

Expanded Access Protocol of 68Ga-PSMA-11 for PET Imaging

Prostate Cancer

United States
Case Comprehensive Cancer Center

Withdrawn

Intervention for Caregivers of Patients Who Have Recently Undergone HSCT

Caregiver Distress | Caregiver Anxiety | Caregiver Health Related QOL
Case Comprehensive Cancer Center

Completed

Optimal Timing of Postoperative Magnetic Resonance Imaging (MRI) in Patients With Extradural Spinal

Spinal Tumor

United States
Case Comprehensive Cancer Center

Completed

Feasibility of a Social Media-based Weight Loss Program for Low Socioeconomic Status Individuals

Obesity

United States
Case Comprehensive Cancer Center

Completed

KV-CBCT and Ultrasound Imaging in Guiding Radiation Therapy in Patients With Prostate, Liver, or Pancreatic Cancer

Prostate Carcinoma | Adult Liver Carcinoma | Malignant Pancreatic Neoplasm

United States
Jonsson Comprehensive Cancer Center

Completed

Bevacizumab, Temozolomide, and External Beam Radiation Therapy as First-Line Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

Brain and Central Nervous System Tumors

United States
Jonsson Comprehensive Cancer Center

Completed

Fluorine F 18 Clofarabine PET/CT in Imaging Patients With Autoimmune or Inflammatory Diseases

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Crohn Disease | Takayasu Arteritis | Autoimmune Disease | Inflammatory Disorder

United States
Case Comprehensive Cancer Center

Completed

Radiation Therapy in Treating Patients With Recurrent Breast Cancer

Breast Cancer

United States
Case Comprehensive Cancer Center

Completed

Radiation Therapy Cisplatin With or Without Fluorouracil Patients With Stage III or Stage IV Head and Neck Cancer

Head and Neck Cancer

United States
Jonsson Comprehensive Cancer Center

Completed

Vaccine Therapy in Treating Young Patients Who Are Undergoing Surgery for Malignant Glioma

Brain and Central Nervous System Tumors

United States
Jonsson Comprehensive Cancer Center

Completed

Radiation Therapy With or Without Surgery in Treating Patients Who Have Brain Metastases

Metastatic Cancer

United States
Jonsson Comprehensive Cancer Center

Completed

Vaccine Therapy in Treating Patients With Stage IV or Relapsed Malignant Melanoma

Melanoma

United States
Jonsson Comprehensive Cancer Center

Completed

Celecoxib in Preventing Non-Small Cell Lung Cancer in Tobacco Smokers

Lung Cancer

United States
Jonsson Comprehensive Cancer Center

Completed

Voriconazole Compared With Itraconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Cancer

United States
Jonsson Comprehensive Cancer Center

Completed

Irinotecan and Paclitaxel in Treating Patients With Metastatic or Recurrent Cancer of the Esophagus or Stomach

Gastric Cancer | Esophageal Cancer

United States
Jonsson Comprehensive Cancer Center

Withdrawn

SCH 66336 With or Without Gemcitabine Followed by Surgery Compared With Surgery Alone in Treating Patients With Primary Liver Cancer

Liver Cancer
Jonsson Comprehensive Cancer Center

Withdrawn

Bimatoprost Ophthalmic Solution in Increasing Eyebrow and Eyelash Growth in Patients Who Have Undergone Chemotherapy for Breast Cancer and in Healthy Participants

Breast Cancer | Alopecia

United States
Case Comprehensive Cancer Center

Completed

Arsenic Trioxide, Ascorbic Acid, Dexamethasone, and Thalidomide in Myelofibrosis/Myeloproliferative Disorder

Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Myelodysplastic/Myeloproliferative Diseases

United States
Case Comprehensive Cancer Center

Completed

Docetaxel,Carboplatin,Trastuzumab and Bevacizumab for Breast Cancer and Bone Marrow Micrometastases

Breast Cancer

United States
Case Comprehensive Cancer Center

Completed

Low-Residue Diet in Treating Diarrhea in Patients Receiving Pelvic Radiation Therapy.

Sarcoma | Cervical Cancer | Diarrhea | Prostate Cancer | Radiation Toxicity

United States

Clinical Trials Sponsored by UNC Lineberger Comprehensive Cancer Center

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