Clinical Trials Sponsored by UNC Lineberger Comprehensive Cancer Center

Total 5617 results

UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Erlotinib in Treating Patients With Progressive Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

High-Dose Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory Metastatic Breast Cancer

Breast Cancer

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Octreotide in Treating Patients With Locally Advanced or Metastatic Liver Cancer

Liver Cancer

United States
UNC Lineberger Comprehensive Cancer Center
Stand Up To Cancer; University Cancer Research Fund at Lineberger Comprehensive...

Recruiting

Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL

Neoplasms | Immune System Diseases | Lymphoma | Lymphoproliferative Disorders | Lymphatic Diseases | Immunoproliferative Disorders | Mycosis Fungoides | Sezary Syndrome | Cutaneous T Cell Lymphoma | Gray Zone Lymphoma | Cutaneous Lymphoma | Lymphomatoid Papulosis | Cutaneous Anaplastic Large Cell Lymphoma

United States
UNC Lineberger Comprehensive Cancer Center
The Duke Endowment

Recruiting

enCompass Carolina: A Social Support and Coaching Program for Cancer Caregivers

Cancer

United States
UNC Lineberger Comprehensive Cancer Center
Rising Tide Foundation

Completed

High Dose Intravenous Thiamine for the Prevention of Delirium in Allogeneic Hematopoietic Stem Cell Transplantation

Delirium | Hematopoietic Stem Cell Transplantation | Thiamine Deficiency

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Impact of Financial Incentives

Human Papilloma Virus

United States
UNC Lineberger Comprehensive Cancer Center
Breast Cancer Research Foundation

Recruiting

Impact of Home-based Aerobic and Strength Exercises During Chemotherapy for Early Breast Cancer on Biomarkers of Aging

Breast Cancer

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Registry of Older Patients With Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Cognitive/Functional Effects | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Nonmalignant Neoplasm | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Correlation of Molecular Markers With Response to Therapy and Breast Cancer Behavior

Breast Cancer

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

High Intensity Interval Training in Endometrial Cancer

Endometrial Cancer

United States
UNC Lineberger Comprehensive Cancer Center
Golfers Against Cancer Grant

Active, not recruiting

Metformin With the Levonorgestrel-Releasing Intrauterine Device for the Treatment of Complex Atypical Hyperplasia (CAH) and Endometrial Cancer (EC) in Non-surgical Patients

Endometrial Cancer | Complex Atypical Hyperplasia

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Fathers and Mothers Invested in Lives of Their Youth (FAMILY) Study: A Pilot Intervention (FAMILY)

Parenting | Metastatic Breast Cancer

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Effect of Human Papillomavirus Self-Collection on Cervical Cancer Screening in High Risk Women: My Body, My Test 3 (MBMT-3)

Cervical Cancer | Uterine Cervical Neoplasms | Human Papillomavirus

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

A Patient Portal Tool, E-assist, for Supporting CRC Screening

Colorectal Cancer

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Investigating Chemotherapy Treatments, Response and Subsets of HIV-associated Kaposi Sarcoma in Malawi

HIV | Kaposi Sarcoma

Malawi
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Enhancing Source Credibility in Tobacco Regulatory Communications

Cigarette Smoking Behavior

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Comparison of the Sensitivity and Specificity of Acoustic Angiography to the Sensitivity and Specificity of Conventional Ultrasound

Signs and Symptoms

United States
UNC Lineberger Comprehensive Cancer Center
Breast Cancer Research Foundation

Completed

The Impact of a Physical Activity Program on Biomarkers of Aging During Chemotherapy for Breast Cancer

Breast Cancer | Aging

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Everolimus, Fluorouracil, Leucovorin, Panitumumab, and Oxaliplatin in Treating Patients With Tumors That Did Not Respond to Treatment

Unspecified Adult Solid Tumor, Protocol Specific

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Effect of Aprepitant on Cyclophosphamide Pharmacokinetics in Patients With Breast Cancer (NRR)

Breast Cancer | Nausea and Vomiting

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Use of Palliative Performance and Symptom Distress Scales in Older Patients With Advanced Ovarian Cancer

Ovarian Cancer

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Biomarker-Guided Fluorouracil in Treating Patients With Colorectal Cancer Receiving Combination Chemotherapy

Diarrhea | Colorectal Cancer | Neutropenia

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Trastuzumab and External Beam Radiation Therapy in Treating Women With Stage III or Stage IV Breast Cancer

Breast Cancer
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Sorafenib in Treating Patients With Locally Advanced or Metastatic Liver Cancer and Cirrhosis

Liver Cancer

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Celecoxib in Treating Patients With Relapsed Prostate Cancer Following Radiation Therapy or Radical Prostatectomy

Prostate Cancer

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Irinotecan, Cisplatin, and Radiation Therapy With or Without Celecoxib in Treating Patients With Stage II, Stage III, or Stage IV Esophageal Cancer

Esophageal Cancer
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Doxorubicin Hydrochloride Liposome and Bortezomib in Treating Patients With Refractory Hematologic Cancer or Malignant Solid Tumor or Metastatic Breast Cancer

Lymphoma | Leukemia | Breast Cancer | Ovarian Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Carboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced or Metastatic Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Withdrawn

Carboplatin, Ixabepilone, and Cetuximab in Patients With Stage III or Stage IV Non-Small Cell Lung Cancer Previously Untreated With Chemotherapy

Lung Cancer
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Capecitabine, Paclitaxel, and Trastuzumab in Treating Patients With Metastatic Breast Cancer

Breast Cancer

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Urine HPV Testing for Cervical Cancer Screening Among Women Living With HIV in South Africa

Cervical Cancer | CIN2 | CIN3

South Africa
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Acceptability and Feasibility of Combination Treatment for Cervical Precancer Among South African Women Living With HIV (ACT2)

Cervical Cancer | Human Immunodeficiency Virus | Human Papillomavirus | CIN2 | CIN3

South Africa
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Addressing Cancer-Related Financial Toxicity in Rural Oncology Care Settings

Neoplasms | Carcinoma

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Study of Kappa Chimeric Antigen Receptor (CAR) T Lymphocytes Co-Expressing the Kappa and CD28 CARs for Relapsed/Refractory Kappa+ Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.

Follicular Lymphoma | Splenic Marginal Zone Lymphoma | Mantle Cell Lymphoma | Indolent Non-hodgkin Lymphoma | Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue | Nodal Marginal Zone Lymphoma

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

3-D Super Resolution Ultrasound Microvascular Imaging

Breast Cancer | Thyroid Cancer

United States
UNC Lineberger Comprehensive Cancer Center
Breast Cancer Research Foundation

Suspended

LCCC1931:Post-treatment Intervention in Women With Breast Cancer (70y/o+)

Breast Cancer

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Little Cigar and Cigarillo Warnings Among US Adults Who Use LCCs

Tobacco Use

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Correcting Public Misperceptions About Very Low Nicotine Content Cigarettes

Tobacco Use, Cigarette Use

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Biomarkers in Patients With Rectal Cancer Undergoing Chemotherapy and Radiation Therapy

Colorectal Cancer

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Clinical Evaluation of Primary Sampling Scatter Correction for Chest Tomosynthesis

Pulmonary Nodule, Solitary | Pulmonary Nodule, Multiple

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Comparison of Stationary Breast Tomosynthesis and 2-D Digital Mammography in Patients With Known Breast Lesions

Breast Neoplasms

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Sorafenib Tosylate and Chemoembolization With Doxorubicin Hydrochloride and Mitomycin in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery

Liver Cancer

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Carboplatin, Pemetrexed Disodium, and Bevacizumab for Patients With Stage III or IV Non-Small Cell Lung Cancer Who Are Light/Never Smokers

Lung Cancer

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Studying Blood Samples From Women With Breast Cancer or Ductal Carcinoma In Situ Who Are Receiving Tamoxifen (NRR)

Breast Cancer | Menopausal Symptoms

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Reduced-Intensity Busulfan and Fludarabine With or Without Antithymocyte Globulin Followed by Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Lapatinib and Radiation Therapy in Treating Patients With Locally Recurrent or Chemotherapy-Refractory Locally Advanced or Metastatic Breast Cancer

Breast Cancer

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Mammography Reminders for Encouraging Women to Undergo Regular Mammography Screenings for Breast Cancer

Breast Cancer
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Genistein in Preventing Breast or Endometrial Cancer in Healthy Postmenopausal Women

Breast Cancer | Endometrial Cancer

United States

Clinical Trials Sponsored by UNC Lineberger Comprehensive Cancer Center

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Uganda

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations