Clinical Trials Sponsored by UniQure N.V.

Total 1465 results

UniQure Biopharma B.V.

Not yet recruiting

Safety, PK/PD, and Exploratory Efficacy Study of AMT-191 in Classic Fabry Disease

Fabry Disease
UniQure Biopharma B.V.

Recruiting

Safety and Proof-of-Concept (POC) Study With AMT-130 in Adults With Early Manifest Huntington's Disease

Huntington's Disease

United States
UniQure Biopharma B.V.

Not yet recruiting

Safety, Tolerability, and Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Amyotrophic Lateral Sclerosis (ALS) Patients With SOD1 Mutations

Amyotrophic Lateral Sclerosis
uniQure France SAS

Recruiting

AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy

Mesial Temporal Lobe Epilepsy

United States
UniQure Biopharma B.V.

Recruiting

Safety and Efficacy of AMT-130 in European Adults With Early Manifest Huntington's Disease

Huntington Disease

Germany, Poland, United Kingdom
UniQure Biopharma B.V.

Completed

Glybera Registry, Lipoprotein Lipase Deficient (LPLD) Patients (GENIALL)

Lipoprotein Lipase Deficiency | Familial Hyperlipoproteinemia Type 1 | Familial Hyperchylomicronemia

Germany
Haemnet
UniQure Biopharma B.V.

Completed

An Exploration of the Impact of Gene Therapy on the Lives of People With Haemophilia and Their Families (Exigency)

Hemophilia

United Kingdom
UniQure Biopharma B.V.
Chiesi Farmaceutici S.p.A.

Withdrawn

Alipogene Tiparvovec for the Treatment of LPLD Patients

LPL Deficiency

Canada, United States
Digna Biotech S.L.
University of Navarra; Porphyria Centre Sweden; UniQure N.V.

Completed

Observational Study of Acute Intermittent Porphyria Patients

Acute Intermittent Porphyria

Spain
UniQure Biopharma B.V.
Institut Pasteur; Venn Life Sciences

Completed

Intracerebral Gene Therapy in Children With Sanfilippo Type B Syndrome

Sanfilippo Syndrome B

France
Digna Biotech S.L.
University of Navarra; Porphyria Centre Sweden; UniQure N.V.; Nationales Centrum...

Completed

Phase I Gene Therapy Clinical Trial Using the Vector rAAV2/5-PBGD for the Treatment of Acute Intermittent Porphyria

Acute Intermittent Porphyria

Spain
Merus N.V.

Recruiting

Study Evaluating Zenocutuzumab in Patients With or Without Molecularly Defined Cancers

Metastatic Castration-resistant Prostate Cancer | NSCLC Harboring NRG1 Fusion

United States
Adenobio N.V

Unknown

Phase II Study for the Diagnosis and Functional Assessment of CAD Using Transthoracic-Echodoppler

Ischemic Heart Disease

France
TiGenix n.v.

Terminated

A Prospective, Post-marketing Registry on the Use of ChondroMimetic for the Repair of Osteochondral Defects (OMCM)

Osteochondral Defects

United Kingdom, Germany, Hungary, Belgium
PharmaNeuroBoost N.V.

Completed

Pipamperone/Citalopram (PipCit)Versus Citalopram in the Treatment of Major Depressive Disorder(MDD)

Depression

United Kingdom
PharmaNeuroBoost N.V.

Completed

Pipamperone/Citalopram (PNB01) Versus Citalopram (CIT) and Versus Pipamperone (PIP) in Major Depressive Disorder (MDD)

Major Depressive Disorder

United States, Canada
PharmaNeuroBoost N.V.

Completed

POC Study of Pipamperone Added to Stable Treatment With RIS or PAL in Chronic Schizophrenia

Schizoaffective Disorder | Chronic Schizophrenia

Belgium
ActoGeniX N.V.

Completed

Study to Assess Safety and Tolerability of AG013 in Oral Mucositis in Subjects Receiving Induction Chemotherapy for the Treatment of Cancers of the Head and Neck

Oral Mucositis

United States
ActoGeniX N.V.

Completed

A Phase 2a Study to Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of AG011 in Ulcerative Colitis

Moderately Active Ulcerative Colitis

Canada, Netherlands, Sweden, Belgium
Recoly N.V.

Completed

Study of the Efficacy of Human Recombinant Factor VIII (Kogenate FS) Reconstituted in Pegylated Liposomes.

Haemophilia A

Russian Federation
Merus N.V.

Recruiting

A Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR and Anti-c-MET Bispecific Antibody, in Patients With Advanced NSCLC and Other Solid Tumors

Gastric Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Non-Small Cell Lung Cancer Metastatic

United States, Spain, France, Italy, Netherlands, Belgium, Korea, Republic of, Germany, Singapore
Merus N.V.

Recruiting

A Study of Zenocutuzumab (MCLA-128) in Patients With Solid Tumors Harboring an NRG1 Fusion (eNRGy)

NSCLC Harboring NRG1 Fusion | Solid Tumours Harboring NRG1 Fusion | Pancreatic Cancer Harboring NRG1 Fusion | NRG1 Fusion

Spain, France, Israel, Belgium, Denmark, United States, Korea, Republic of, Japan, Germany, Netherlands, Austria, Canada, Italy, Norway, Singapore, Sweden, Taiwan, United Kingdom
Merus N.V.

Completed

MCLA-128 With Trastuzumab/Chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer.

Breast Cancer Metastatic

United States, France, Belgium, Spain, United Kingdom, Netherlands, Portugal
Merus N.V.

Available

Early Access Program Providing HER2/HER3 Bispecific Antibody, MCLA-128, for a Patient With Advanced NRG1-Fusion Positive Solid Tumor

Renal Cell Carcinoma | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Pancreatic Cancer | Prostate Cancer | Non Small Cell Lung Cancer | Cholangiocarcinoma | Solid Tumor, Unspecified, Adult | Unknown Primary Tumors | NRG1 Fusion
Merus N.V.

Active, not recruiting

MCLA-117 in Acute Myelogenous Leukemia

Acute Myeloid Leukemia | Acute Myelogenous Leukemia

United States, Italy, Netherlands, Belgium, France
TiGenix n.v.

Completed

RCT of ChondroCelect® (in an ACI Procedure) vs Microfracture in the Repair of Cartilage Defects of the Knee (TIGACT01)

Articular Cartilage Lesion of the Femoral Condyle

Belgium, Croatia, Germany, Netherlands
Sequana Medical N.V.

Recruiting

Management of Volume Overload HF Patients by Individual DSR Treatment adJustment-a clinicAl inVestigation of InfusatE2.0 (MOJAVE)

Heart Failure | Volume Overload

United States
Terumo Europe N.V.

Recruiting

Ultimaster Nagomi™ Sirolimus Eluting Coronary Stent System in Complex PCI Patients (NAGOMI COMPLEX)

Cardiovascular Disease | Ischemic Heart Disease | Coronary Artery Occlusion

Switzerland, Spain, Netherlands, Belgium, United Kingdom, Ireland, Italy, Estonia
Terumo Europe N.V.

Active, not recruiting

Prospective Multicenter Study to Confirm the Performance of the Renzan Stent in Treatment of SFA/POP Artery Disease (PRIZER)

Superficial Femoral Artery Disease | Popliteal Artery Disease

Spain, Belgium, Germany, France, Netherlands
Terumo Europe N.V.

Completed

Holmium-166 Retrospective Collection of Real-World Data (RECORD)

Hepatocellular Carcinoma | Metastatic Cancer

Netherlands, Germany, Switzerland, Belgium, Spain, Portugal, Italy
Terumo Europe N.V.

Terminated

QuiremSpheres Observational Study (Hope166)

Liver, Cancer of, Non-Resectable

Netherlands, Germany
Sequana Medical N.V.

Withdrawn

Malignant Ascites Alfapump® Study (ProMAS)

Malignant Ascites

United Kingdom
Terumo Europe N.V.

Completed

Safety and Efficacy Study of Kaname Coronary Stent System for the Treatment of Patients With Coronary Artery Disease (KARE)

Coronary Artery Disease | Angioplasty, Transluminal, Percutaneous Coronary

Spain, Germany, Serbia, France, Italy
Terumo Europe N.V.

Completed

Safety and Efficacy of TCD-10023 (Ultimaster) Drug-eluting Stent in STEMI Patients - MASTER Study (MASTER)

Acute ST Segment Elevation Myocardial Infarction

Brazil, Serbia, Italy, Spain, Macedonia, The Former Yugoslav Republic of
Sequana Medical N.V.

Completed

ALFApump System Versus Standard of Care in Ascites Treatment

Refractory or Recurrent Ascites

Spain, United Kingdom, Italy, France, Austria
Terumo Europe N.V.

Completed

Assessment of the Manageability and Safety of ADBLOCK Adhesion Barrier System in Laparoscopic Gynaecological Surgery (ADBEE)

UTERINE MYOMAS

Germany
Nipro Europe N.V.

Completed

In Vivo Evaluation of the Nipro Elisio™ Dialyzer

Chronic Kidney Disease

France
Philips Electronics Nederland B.V. acting through...
suAzio N.V.

Completed

Norms and Validation for IntelliSpace Cognition Spanish Version

Cognitive Functioning of Healthy Individuals | Hispanic

United States
Comenius University
Sanatórium of Dr. Guhr, n.o.; Kaneka Pharma Europe N.V.

Completed

Spa Rehabilitation, Antioxidant and Bioenergetic Supportive Treatment of Patients With Post-Covid-19 Syndrome (SpaCOVID)

COVID-19 Respiratory Infection

Slovakia
Terumo Europe N.V.

Recruiting

Holmium-166 Transarterial Radioembolization in Unresectable, Early Stage Hepatocellular Carcinoma. (HOMIE-166)

Hepatocellular Carcinoma

Germany
Sequana Medical N.V.

Withdrawn

Optimal Balance Alfapump® System Feasibility Study (OPTIMALBALANCE)

Heart Failure

Hungary
Sequana Medical N.V.

Completed

ALFApump System Post Marketing Surveillance Registry (2011-AAR-004)

Liver Cirrhosis | Malignant Ascites | Refractory Ascites

Germany, Switzerland, Spain, United Kingdom
Terumo Europe N.V.

Completed

e-NOBORI Observational Registry of Nobori DES (e-NOBORI)

Coronary Artery Disease

Ireland, France, Taiwan, Spain, United Kingdom, Israel, Netherlands, Czechia, Sweden, Bangladesh, Russian Federation, Brazil, Bulgaria, Serbia, Chile, Germany, Hungary, Indonesia, Georgia, Austria, Belarus, Denmark, Egypt, Estonia, Latvia, Lithuan... and more
Terumo Europe N.V.

Unknown

Prospective, Single-arm, Multi Centre Observations Ultimaster Des Registry (e-Ultimaster)

Coronary Artery Disease

Netherlands, France, United Kingdom, Austria, Ireland, Spain, Bulgaria, South Africa, Israel, Hungary, Switzerland, Chile, Belgium, Japan, Argentina, Portugal, United Arab Emirates, Serbia, Malaysia, Brazil, India, Poland, Indonesia, ... and more
Terumo Europe N.V.

Completed

Optical Frequency Domain Imaging (OFDI) Assessed Strut Coverage of New Terumo DES (DISCOVERY123)

Coronary Artery Disease

France, Netherlands, Germany
Trod Medical N.V.

Unknown

Focal Prostate Radiofrequency Ablation (ProRAFT)

Prostate Cancer

United Kingdom
Sequana Medical N.V.

Completed

A (M)Ulti-center, Prospective, (O)Pen Label, Uncontrolled Feasibility (S)Tudy to Assess the Safety and Effectiveness of an Automatic Low Flow (A)Scites (Alfa) Pump (I)n Patients With (C)Irrhosis and Refractory or Recurrent Ascites (MOSAIC)

Cirrhosis | Ascites

Canada, United States
Sequana Medical N.V.

Unknown

Effects of Treatment of Ascites by the ALFApump System on Renal and Circulatory Function

Cirrhosis, Liver | Refractory Ascites

Spain
Terumo Europe N.V.

Recruiting

BioPearl™ Microspheres Loaded With Doxorubicin for the Treatment of Unresectable Hepatocellular Carcinoma (HCC) (BIOPEARL-ONE)

Hepatocellular Carcinoma Non-resectable

Belgium, Germany, Italy
Sequana Medical N.V.

Recruiting

International Alfapump Cohort Study (TOPMOST)

Liver Cirrhoses | Malignant Ascites

Germany, Switzerland

Clinical Trials Sponsored by UniQure N.V.

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bangladesh

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations