Clinical Trials Sponsored by VIVUS, Inc.

Total 35421 results

VIVUS LLC
Synteract, Inc.

Completed

Study of VI-0521 Compared to Placebo in the Glycemic Management of Obese Diabetics

Type 2 Diabetes Mellitus

United States
VIVUS LLC
Medpace, Inc.

Completed

A Study Comparing Multiple Doses of VI-0521 With Placebo and Their Single-agent Constituents for Treatment of Obesity in Adults

Obesity

United States
VIVUS LLC
Medpace, Inc.

Completed

VI-1121 for the Treatment Alzheimer's Disease (AD-201)

Alzheimer's Disease

United States
VIVUS LLC
Medpace, Inc.

Completed

Study of VI-0521 Compared to Placebo in Treatment of Obesity in Adults

Obesity

United States
VIVUS LLC
Medpace, Inc.

Completed

A Safety and Efficacy Study of VI-0521 to Evaluate the Long Term Treatment of Obesity in Adults With Obesity-Related Co-Morbid Conditions. An Extension Study of Protocol OB-303 (NCT00553787)

Obesity
VIVUS LLC

Completed

A Study of VI-0521 for the Treatment of Obstructive Sleep Apnea / Hypopnea Syndrome in Obese Adults

Sleep Apnea

United States
VIVUS LLC

Completed

Long-Term Safety and Efficacy Study of Avanafil in Men With Erectile Dysfunction

Erectile Dysfunction

United States
VIVUS LLC

Completed

Compare the Pharmacokinetics of Omeprazole, Rosiglitazone, and Desipramine When Administered With Avanafil in Healthy Male Subjects

Erectile Dysfunction
VIVUS LLC

Completed

Hemodynamic Study of Avanafil and Two α-Adrenergic Blockers,Doxazosin and Tamsulosin

Erectile Dysfunction

United States
VIVUS LLC

Completed

Assess the Effect of Food on Avanafil Pharmacokinetic (PK), to Compare 2 Oral Formulations of Avanafil,and Investigate Dose Proportionality in Healthy Male Subjects

Healthy
VIVUS LLC

Completed

A Pharmacokinetic Study of Avanfil in Healthy Young Male Subjects

Avanfil ADME | Semen Exposure | Sperm Function

United States
VIVUS LLC

Completed

Evaluate the Effect of VI-0521 on the Pharmacokinetics of Oral Contraceptive in Healthy Female Subjects

Healthy

United States
VIVUS LLC
Medpace, Inc.

Completed

Study of VI-0521 Compared to Placebo in Treatment of Diabetes and Obesity in Adults With Obesity-Related Co-Morbid Conditions

Obesity | Type 2 Diabetes

United States
Rivus Pharmaceuticals, Inc.

Recruiting

Ph 2 Study of the Safety and Efficacy of Three HU6 Dose Levels and Placebo in Nonalcoholic Steatohepatitis

Fatty Liver | Nonalcoholic Steatohepatitis | Non-Alcoholic Fatty Liver Disease

United States
Vivos BioTechnologies, Inc.

Recruiting

Dental Appliance to Treat SDB in Children

Snoring | Sleep-Disordered Breathing | Apnea, Obstructive | Upper Airway Resistance Syndrome

United States
Rivus Pharmaceuticals, Inc.

Completed

Safety and Pharmacokinetics of HU6

Obese

United States
VIVUS LLC
Synteract, Inc.; Sentrx

Terminated

Open-Label Study to Evaluate the Long-Term Safety and Efficacy of VI-0521 in Type 2 Diabetic Adults

Diabetes

United States
VIVUS LLC
Synteract, Inc.; Sentrx

Completed

A VI-0521 Study to Evaluate the Long-term Safety and Efficacy in Type 2 Diabetic Adults

Diabetes

United States
VIVUS LLC

Completed

Safety Study Looking at the Effects of Stendra on Vision

Vision

United States
VIVUS LLC

Completed

Research Evaluating an Investigational Medication for Erectile Dysfunction - Diabetic ED (REVIVE-D) (REVIVE-D)

Erectile Dysfunction

United States
VIVUS LLC

Completed

Research Evaluating an Investigational Medication for Erectile Dysfunction - General ED (REVIVE)

Erectile Dysfunction

United States
VIVUS LLC

Completed

To Assess the Safety of Avanafil in Healthy and Hepatically Impaired Male Subjects. (avanafil)

Erectile Dysfunction
VIVUS LLC

Completed

Study the Effect of Avanafil on the Pharmacodynamics and Pharmacokinetics of Warfarin in Healthy Male Subjects

Erectile Dysfunction
Rivus Pharmaceuticals, Inc.

Recruiting

A Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-HU6

Healthy

United States
Rivus Pharmaceuticals, Inc.

Active, not recruiting

Exploratory Ph 2A, Double-Blind, Placebo-Controlled Dose Escalation Study of Safety, Tolerability, PD, & PK of HU6 for Subjects With Obese HFpEF (HFpEF)

Heart Failure With Preserved Ejection Fraction

United States
Rivus Pharmaceuticals, Inc.

Completed

Phase 2a Study of HU6 in Subjects With Elevated Liver Fat and High BMI Volunteers

NASH - Nonalcoholic Steatohepatitis

United States
Rivus Pharmaceuticals, Inc.

Withdrawn

Ph 2a Study of HU6 on Energy Metabolism, Muscle and Liver Substrate Metabolism, and Mitochondrial Function in Subjects Who Are Overweight or Obese With Type 2 Diabetes

Obesity | Diabete Type 2

United States
Rivus Pharmaceuticals, Inc.

Completed

Multiple Ascending Dose Study of HU6 in High BMI Volunteers

NASH - Nonalcoholic Steatohepatitis

United States
Rivus Pharmaceuticals, Inc.

Completed

Ascending Dose Study of HU6 in Healthy Volunteers

NASH - Nonalcoholic Steatohepatitis

United States
VIVUS LLC

Completed

A Study of VI-0521 on Ambulatory Blood Pressure in Overweight or Obese Subjects

Blood Pressure

United States
VIVUS LLC

Completed

A Phase IV Safety and Efficacy Study of VI-0521 in Adolescents With Obesity

Adolescent Obesity | Obesity in Adolescence | Adolescent Overweight

United States
VIVUS LLC

Completed

A Pharmacokinetic Study Comparing VI-0521 With Placebo in Obese Adolescents

Pediatric Obesity | Childhood Obesity

United States
VIVUS LLC

Completed

Effect of VI-0521 (Qsymia®) on Glomerular Filtration Rate (GFR) in Overweight or Obese Healthy Subjects

Obesity

United States
VIVUS LLC

Completed

Study Evaluating the Effects of Avanafil on Semen Parameters

Erectile Dysfunction

United States
VIVUS LLC

Completed

Research Evaluating a PDE5 Inhibitor for Erectile Dysfunction

Erectile Dysfunction

United States
VIVUS LLC

Completed

Research Evaluating an Investigational Medication for Erectile Dysfunction - Post-Prostatectomy

Erectile Dysfunction

United States
VIVUS LLC

Completed

Study to Evaluate Hemodynamic Response to to a Sublingual Dose of Glyceryl Trinitrate in Subjects Receiving TA-1790, Sildenafil Citrate, and Placebo

Erectile Dysfunction

United States
VIVUS LLC

Completed

Drug Interaction Study of Avanafil and Enalapril or Amlodipine

Erectile Dysfunction

United States
VIVUS LLC

Terminated

A Pharmacokinetic (PK) Study to Compare the Absorption of Two Formulations of Transdermal Testosterone Spray and Intrinsa®

Hypoactive Sexual Desire Disorder

United States
VIVUS LLC

Completed

Pharmacokinetic Comparison of Multiple Formulations of Topiramate and Phentermine in Obese Adults

Obesity

United States
VIVUS LLC

Completed

A Phase I Crossover Study of the Hemodynamic Interactions of Avanafil & Alcohol in Healthy Male Subjects.

Erectile Dysfunction
VIVUS LLC

Completed

To Compare the Pharmacokinetics of Avanafil in Subjects With Mild and Moderate Renal Impairment to Subjects With Normal Renal Function.

Renal
VIVUS LLC

Completed

A Study to Evaluate How VI-0521 Affect Cardiac Repolarization in Healthy Male and Female Volunteers (TQT)

Torsades de Pointes

United States
VIVUS LLC

Completed

A Drug Interaction Study of VI-0521 With Metformin, Sitagliptan and Probenecid in Healthy Subjects.

Obesity

United States
VIVUS LLC

Completed

To Evaluate The Effect Of Ketoconazole, Ritonavir and Erythromycin on the Safety and Pharmacokinetics of Avanafil

Erectile Dysfunction

United States
VIVUS LLC

Completed

A Study to Evaluate the Pharmacokinetics of VI-0521 Subjects With Renal Impairment

Renal Impairment

United States
VIVUS LLC

Completed

Topical Alprostadil for Female Sexual Arousal Disorder

Sexual Dysfunction, Physiological

United States
VIVUS LLC
Covance

Completed

A Thorough EKG Safety Study of TA-1790 (Avanafil)

Erectile Dysfunction

United States
Vicus Therapeutics

Terminated

Efficacy and Safety Study of Etodolac and Propranolol in Patients With Clinically Progressive Prostate Cancer

Prostatic Neoplasms

United States
Vicus Therapeutics

Completed

Regimen for the Treatment of Cachexia in Subjects With NSCLC (VT-122)

Cachexia

India, United States

3

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