Clinical Trials Sponsored by Vall d'Hebron Institute of Oncology (VHIO)

Total 76 results

Vall d'Hebron Institute of Oncology

Recruiting

Predictive Biomarkers of Response to Checkpoint Inhibitors in Triple Negative Breast Cancer: a Multiomics Platform (PORTRAIT)

Triple Negative Breast Cancer

Spain
Vall d'Hebron Institute of Oncology

Active, not recruiting

Phase II Study of Avelumab Plus Chemotherapy in the Peri-operative Treatment for Patients With Resectable Gastric Cancer (GC) or Gastroesophageal Junction Cancer (GEJC) (MONEO)

Stomach Neoplasms | Gastroesophageal Junction Adenocarcinoma

Spain
Vall d'Hebron Institute of Oncology

Completed

Pembrolizumab in Combination With Doxorubicin in Advanced, Recurrent or Metastatic Endometrial Cancer (TOPIC)

Endometrial Neoplasms

Spain
Palobiofarma SL
Vall d'Hebron institute of oncology (VHIO), Catalan institute of oncology...

Completed

Study of PBF-999 in Solid Tumour Advanced Cancer

Cancer

Spain
Grupo Espanol Multidisciplinario del Cancer Digestivo
AstraZeneca; Vall d'Hebron Institute of Oncology (VHIO)

Recruiting

Durvalumab (MEDI4736) Plus Total Neoadjuvant Therapy (TNT) in Locally Advanced Rectal Cancer (DUREC)

Rectal Cancer

Spain
Vall d'Hebron Institute of Oncology
Prostate Cancer Foundation; Instituto de Salud Carlos III; Hospital Vall d'Hebron and other collaborators

Recruiting

Whole-Body Diffusion-Weighted Magnetic Resonance Imaging (MRI) as a Response Biomarker for Metastatic Prostate Cancer (iPROMET)

Prostate Cancer Metastatic

Spain
Vall d'Hebron Institute of Oncology
Banc de Sang i Teixits

Recruiting

Assessment of the Safety and Tolerability of ex Vivo Next-generation Neoantigen-selected Tumor-infiltrating Lymphocyte (TIL) Therapy in Advanced Epithelial Tumors and Immune Checkpoint Blockade (ICB) Resistant Solid Tumors (NEXTGENTIL-ACT)

Epithelial Tumors, Malignant | Malignant Solid Tumor

Spain
Queen Mary University of London
AstraZeneca; Vall d'Hebron Institute of Oncology

Active, not recruiting

MEDI4736 Combinations in Metastatic Renal Cell Carcinoma (CALYPSO)

Renal Clear Cell Carcinoma | Renal Papillary Cell Carcinoma

United Kingdom
Banc de Sang i Teixits
Vall d'Hebron Research Institute (VHIR)

Completed

Autologous Mesenchymal Stromal Cells for Multiple Sclerosis (EMMES)

Relapsing-Remitting Multiple Sclerosis | Secondary Progressive Multiple Sclerosis

Spain
Vall d'Hebron Institute Research
Hospital Clinic of Barcelona

Recruiting

Impact of the Ex-vivo Pulmonary Perfusion System on the Microbiome of Lung Grafts and Their Inflammatory Reaction. (ExBioma)

Lung Transplant Failure

Spain
UNICANCER
SOLTI Breast Cancer Research Group; Vall d'Hebron Institute of Oncology; MSD...

Not yet recruiting

Pembrolizumab and Chemotherapy Treatment or no Treatment Guided by the Level of TILs in Resected Early-stage TNBC (ETNA)

Triple-negative Breast Cancer
Fondazione IRCCS Istituto Nazionale dei Tumori,...
The Netherlands Cancer Institute; Vall d'Hebron Institute of Oncology

Recruiting

Pilot Study on the Use of iENTER, iCONSENT and iPARTICIPATE E-tools

Cancer

Italy
Vall d'Hebron Institute of Oncology
European Organisation for Research and Treatment of Cancer - EORTC

Terminated

Study With Atezolizumab Plus Bevacizumab in Patients With Chemotherapy Resistant, MSI-like, Colorectal Cancer

Chemotherapy | ColoRectal Cancer | MSI | Resistance, APC

Belgium, Netherlands, Spain, Italy
Banc de Sang i Teixits
Hospital Universitario La Fe; Vall d'Hebron Institute of Oncology

Completed

Virus-specific Activated T Lymphocytes From a Donor in Hematopoietic Progenitor Transplanted Patients

CMV Viremia | Immunosuppression-related Infectious Disease

Spain
Hospital Universitari Vall d'Hebron Research Institute
University of Barcelona

Unknown

Modified Intrapartum Sims Position-related Efficiency in Correction of Persistent Foetal OP Positions (MSIMSFPOP)

Persistent Occiput Posterior Position During Labor

Spain
Hospital Universitari Vall d'Hebron Research Institute
Hospital Clinic of Barcelona

Recruiting

Attempted Suicide Intervention Treatment and Prevention (SAMIT Program) (SAMIT)

Suicide, Attempted | Suicide Prevention

Spain
Hospital Universitari Vall d'Hebron Research Institute
University of South Australia

Unknown

New Educational Tool for FM

Fibromyalgia

Spain
Hospital Universitari Vall d'Hebron Research Institute
Hospital Clinic of Barcelona; Hospital Universitari de Bellvitge; Hospital Vall... and other collaborators

Completed

Multicenter, Randomized Placebo-controlled Clinical Trial to Evaluate the Effect of Perioperative Use of Tranexamic Acid on Transfusion Requirements and Surgical Bleeding in Major Spine Surgery

Hemorrhage | Blood Transfusion | Spinal Fusion | Antifibrinolytic Agents

Spain
Vall d'Hebron Institute of Oncology
Taisho Pharmaceutical Co., Ltd.; Roche Pharma AG; Iqvia Pty Ltd; Janssen, LP

Recruiting

A Modular Multi-Basket Trial to Improve Personalized Medicine in Cancer Patients (Basket of Baskets) (BoB)

Advanced Solid Tumor

Spain, France, Germany, Netherlands, Sweden, United Kingdom, Italy
Hospital Universitari Vall d'Hebron Research Institute
Department of Health, Generalitat de Catalunya

Unknown

Implementation of an Early Rehabilitation Program for the Patient With Lung Transplantation: From the ICU to Home.

Rehabilitation | Lung Transplant

Spain
Cure 51
Centre Leon Berard; Charite University, Berlin, Germany; Gustave Roussy, Cancer... and other collaborators

Recruiting

Analyzing and Solving Exceptional Long-term Survivors in Solid Tumors With Poor Prognosis (ROSALIND)

Pancreas Adenocarcinoma | Small-cell Lung Cancer | Glioblastoma, IDH-wildtype

France
Vall d'Hebron Institute of Oncology
Hospital del Mar; Fundació Institut de Recerca de l'Hospital de la Santa Creu...

Recruiting

Machine Learning Model to Predict HOLS and Mortality After Discharge in Hospitalized Oncologic Patients (PLANTOLOGY)

Quality of Life | Solid Tumor | Artificial Intelligence | Tumor | Oncology | Comorbidities and Coexisting Conditions | Mental Status Change | Nutrition Related Neoplasm/Cancer

Spain
Hospital Universitari Vall d'Hebron Research Institute
Spanish Society of Pneumology and Thoracic Surgery

Unknown

Efficacy of a Coaching Program to Promote Physical Activity and Reduce Sedentary Behavior After a COPD Hospitalization

Chronic Obstructive Pulmonary Disease | Physical Activity | Sedentary Lifestyle

Spain
Fondazione IRCCS Istituto Nazionale dei Tumori,...
University of Chicago; Shaare Zedek Medical Center; Vall d'Hebron Institute of... and other collaborators

Recruiting

I3LUNG: Integrative Science, Intelligent Data Platform for Individualized LUNG Cancer Care With Immunotherapy

Lung Cancer Metastatic | Non Small Cell Lung Cancer | Lung Adenocarcinoma | Lung Cancer, Nonsmall Cell

United States, Spain, Greece, Israel
Fundació Institut Germans Trias i Pujol
Hospital Vall d'Hebron; Department of Health, Generalitat de Catalunya

Not yet recruiting

Feasibility and Impact of Online HIV/STI Screening Addressed to PrEP Users in Spain (TESTATE_PrEP)

HIV | STI
Hospital Universitari Vall d'Hebron Research Institute
Erasme University Hospital; Cyprus Institute of Neurology and Genetics; EuroBloodNet...

Recruiting

RADeep Multicenter European Epidemiological Platform for Patients Diagnosed With Rare Anemia Disorders (RADs) (RADeep)

Iron Metabolism Disorders | Sickle Cell Disease | Thalassemia | Hemolytic; Anemia, Hereditary, Due to Enzyme Disorder | Anemia Due to Membrane Defect | CDA | Sideroblastic Anemia | Constitutional Aplastic Anemia | Hereditary Anemia

Spain
Hospital Universitari Vall d'Hebron Research Institute
Institut Català d'Oncologia ICO Girona; Servicio de Geriatría Complejo Hospitalario... and other collaborators

Enrolling by invitation

PeRsonalizing the Approach to the Oncologic Frail Individual Through Tailored Assessment and Intervention (PROFIT Study) (PROFIT)

Lung Cancer | Frail Elderly Syndrome | Prostate Cancer | Older Adults | Gastro-Intestinal Cancer

Andorra, Spain
PIQUR Therapeutics AG
Hospital Universitari Vall d'Hebron Research Institute; Institut Català d'Oncologia and other collaborators

Completed

PQR309 and Eribulin in Metastatic HER2 Negative and Triple-negative Breast Cancer (PIQHASSO)

Metastatic Breast Cancer

Spain, United Kingdom
Laminar Pharmaceuticals
Royal Marsden NHS Foundation Trust; Vall d'Hebron Institute of Oncology; Specialized... and other collaborators

Completed

A Phase 1/2A Study of LAM561 in Adult Patients With Advanced Solid Tumours

Glioma | Other Solid Tumours

Spain, United Kingdom
Vall d'Hebron Institute of Oncology
Hospital del Mar; Clinica Universidad de Navarra, Universidad de Navarra; Puerta... and other collaborators

Recruiting

A Study of Allogenic Natural Killer Cells in Combination With Trastuzumab and Pertuzumab in Adult Patients With Refractory Metastatic Her2 Positive Breast Cancer. NK-ACT-BC_2020

Breast Neoplasms

Spain
Hospital Clinic of Barcelona
Hospital Universitari Vall d'Hebron Research Institute; Fundació Institut de...

Completed

Ambulatory Adaptation to Non-Invasive Mechanical Ventilation

Chronic Respiratory Failure
Corporacion Parc Tauli
Hospital Universitari Vall d'Hebron Research Institute; Hospital Clinic of... and other collaborators

Completed

Biomarkers in Patients Undergoing Mechanical Ventilation (VAP)

Ventilator Associated Pneumonia

Spain
Hospital Universitari Vall d'Hebron Research Institute
University of Vienna; University of Helsinki; Aalto University; Firstbeat Technologies... and other collaborators

Completed

PREventive Care Infrastructure Based On Ubiquitous Sensing (PRECIOUS). VHIR Pilot. (PRECIOUS)

Obesity

Spain
Hospital Universitari Vall d'Hebron Research Institute
Department of Health, Generalitat de Catalunya; GETTEII ( Grupo Enfermero de...

Completed

Telephone-based Motivational Interviewing for Smoking Cessation in Crohn's Disease Patients

Crohn Disease
NanoString Technologies, Inc.
Hospital General Universitario Gregorio Marañon; Cedar Associates LLC; Illumina... and other collaborators

Completed

A Prospective Observational Study of Clinical Outcomes for the NanoString® Technologies Prosigna Gene Signature Assay

Breast Cancer

Spain
Hospital Universitari de Bellvitge
Hospital Clinic of Barcelona; Institut d'Investigació Biomèdica de Girona Dr... and other collaborators

Completed

Refractory Status Epilepticus Treatment Study

Grand Mal Status Epilepticus | Non-convulsive Status Epilepticus

Spain
Institut Català d'Oncologia
Hospital Clinic of Barcelona; Hospital Universitari de Bellvitge; Fundació Institut... and other collaborators

Completed

Effectiveness of a Smoking Cessation Quit Line for Mental Health Patients (QUITMENTAL)

Smoking Cessation | Motivation | Mental Disorder

Spain
Fundación para la Investigación del Hospital Clínico...
Pontificia Universidad Catolica de Chile; Amsterdam UMC, location VUmc; Vall... and other collaborators

Recruiting

Gastric Cancer Risk Factors Knowledge in European and Latinamerican Population (LEGACY-3)

Gastric Cancer

Argentina, Chile, Mexico, Netherlands, Paraguay, Portugal, Spain
Fundación para la Investigación del Hospital Clínico...
Pontificia Universidad Catolica de Chile; Amsterdam UMC, location VUmc; Vall... and other collaborators

Recruiting

Advanced GC Multi-omic Characterization in EU and CELAC Populations (LEGACY-2)

Gastric Cancer

Spain, Chile, Netherlands, Paraguay, Portugal, Argentina, Mexico
Fundación para la Investigación del Hospital Clínico...
Pontificia Universidad Catolica de Chile; Amsterdam UMC, location VUmc; Vall... and other collaborators

Recruiting

Gastric Cancer Risk Factors Associated With EU and CELAC Populations (LEGACY-1)

Cancer, Gastric

Spain, Argentina, Chile, Netherlands, Paraguay, Portugal, Mexico
Technische Universität Dresden
Radboud University Medical Center; UMC Utrecht; Cambridge University Hospitals... and other collaborators

Active, not recruiting

A Retrospective Analysis of Magnetic Resonance Imaging Data for Breast Cancer Screening in the Open Consortium for Decentralized Medical Artificial Intelligence (ODELIA)

Breast Cancer

Germany
The Netherlands Cancer Institute
Eli Lilly and Company; Universitaire Ziekenhuizen KU Leuven; European Organisation... and other collaborators

Unknown

Vinorelbine in Advanced BRAF-like Colon Cancer (EORTC1616)

Colon Cancer

Netherlands
Parc Sanitari Pere Virgili
Consorci Sanitari Integral; Vall d'Hebron Institute of Research; Health and Ageing... and other collaborators

Recruiting

IMAGINE Study Protocol (IMAGINE)

Patients (>=60 Years Old) Suffering From Mild-moderate Stroke (Ischemic or Hemorrhagic, Stroke Severity Assessed by NIHSS <16 Points)

Spain, Sweden
The Netherlands Cancer Institute
Eli Lilly and Company; Universitaire Ziekenhuizen KU Leuven; European Organisation... and other collaborators

Withdrawn

Galunisertib and Capecitabine in Advanced Resistant TGF-beta Activated Colorectal Cancer (EORTC1615)

Colorectal Cancer Metastatic

Netherlands
The Netherlands Cancer Institute
Eli Lilly and Company; Universitaire Ziekenhuizen KU Leuven; European Organisation... and other collaborators

Unknown

LY3200882 and Capecitabine in Advanced Resistant TGF-beta Activated Colorectal Cancer (EORTC1615)

Colorectal Cancer Metastatic
Hospital Mutua de Terrassa
Institut Català de la Salut; Hospital Vall d'Hebron; Public Health Agency of... and other collaborators

Unknown

Tuberculosis In Children Visiting Friends and Relatives

Tuberculosis Infection

Spain
Prof. Tobias Feuchtinger
European Commission; Simbec-Orion Group Ltd, Merthyr Tydfil, UK; Miltenyi Biotec... and other collaborators

Recruiting

Multivirus-specific T-cell Transfer Post SCT vs AdV, CMV and EBV Infections (TRACE)

CMV Infection | EBV Infection | Stem Cell Transplant Complications | AdV Infection

Belgium, Spain, France, Germany, Italy, Netherlands
University of Pittsburgh
National Institute on Alcohol Abuse and Alcoholism (NIAAA); King's College... and other collaborators

Completed

Integrated Approaches for Identifying Molecular Targets in Alcoholic Hepatitis (InTeam)

Alcoholic Hepatitis | Control Patients

United States
Yaqrit Ltd
Assistance Publique - Hôpitaux de Paris; IRCCS Azienda Ospedaliero-Universitaria... and other collaborators

Withdrawn

Safety and Tolerability of Yaq-001 in Patients With Non-Alcoholic Steatohepatitis

Non-Alcoholic Steatohepatitis

France, Italy, Portugal, Spain, Switzerland, United Kingdom
Yaqrit Ltd
Assistance Publique - Hôpitaux de Paris; IRCCS Azienda Ospedaliero-Universitaria... and other collaborators

Terminated

Safety and Tolerability of Yaq-001 in Patients With Cirrhosis

Liver Cirrhosis

France, Italy, Portugal, Spain, United Kingdom, Switzerland

Clinical Trials Sponsored by Vall d'Hebron Institute of Oncology (VHIO)

Sponsors and Collaborators

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