Clinical Trials Sponsored by Wellcome Trust Sanger Institute, UK

Total 427 results

University of Dundee
Wellcome Trust; Diabetes UK

Completed

Genetics of Diabetes Audit and Research in Tayside Scotland (DOLORisk Dundee) (GoDARTS)

Diabetic Neuropathic Pain

United Kingdom
University of Oxford
Wellcome Trust; National Institute for Health Research, United Kingdom; Arthritis...

Completed

Epidemiology and Outcomes of Upper Limb Surgery: Analysis of Routine Data

Osteoarthritis | Rotator Cuff Tear | Avascular Necrosis | Inflammatory Arthritis | Shoulder Dislocation | Dupuytren Contracture | Impingement Syndrome, Shoulder | Elbow Arthropathy | Trigger Digit | Shoulder Arthropathy | Upper Limb Nerve Lesion | Wrist Arthropathy | Fracture Elbow | Dislocations | Fracture, Shoulder | Arthropathy... and other conditions
Bill & Melinda Gates Medical Research Institute
Wellcome Trust

Completed

Safety and Immunogenicity of a Mycobacterium Tuberculosis Vaccine M72/AS01E in Participants With Well-controlled HIV (MESA-TB)

Human Immunodeficiency Virus

South Africa
Velindre NHS Trust
AstraZeneca; Cancer Research UK

Unknown

Fulvestrant +/- Vandetanib in Advanced Aromatase Inhibitor Resistant Breast Cancer (FURVA)

Neoplasms

United Kingdom
National Heart, Lung, and Blood Institute (NHLBI)
Wellcome Trust

Completed

INTERSALT: International Study of Sodium, Potassium, and Blood Pressure

Heart Diseases | Cardiovascular Diseases | Hypertension
Lisette Nixon
Cancer Research UK

Recruiting

Study of Chemoradiotherapy in Oesophageal Cancer Including PET Response and Dose Escalation (SCOPE2)

Oesophageal Cancer

United Kingdom
The Christie NHS Foundation Trust
Cancer Research UK

Completed

Active Symptom Control Alone or With mFOLFOX Chemotherapy for Locally Advanced/ Metastatic Biliary Tract Cancers (ABC06)

Cholangiocarcinoma | Biliary Tract Cancer | Gallbladder Cancer | Ampullary Cancer

United Kingdom
Lisette Nixon
Cancer Research UK

Unknown

A Feasibility Study of Chemo-radiotherapy to Treat Operable Oesophageal Cancer (NeoSCOPE)

Oesophageal Cancer

United Kingdom
The Christie NHS Foundation Trust
Prostate Cancer UK

Recruiting

Hypoxia-driven Prostate Cancer Genomics (HYPROGEN) (HYPROGEN)

Hypoxia | Prostate Cancer

United Kingdom
The Christie NHS Foundation Trust
Pancreatic Cancer UK

Completed

Pancreatic Cancer Dietary Assessment Study (PanDA)

Pancreas Adenocarcinoma | Pancreatic Neoplasm | Malignant Neoplasm of Pancreas | Well-Differentiated Neuroendocrine Carcinoma

United Kingdom
Royal Marsden NHS Foundation Trust
Cancer Research UK

Unknown

CHOP vs GEM-P in 1st Line Treatment of T-cell Lymphoma, Multicentre Phase II Study (CHEMO-T)

Angioimmunoblastic T-cell Lymphoma | Enteropathy-Associated T-Cell Lymphoma | Anaplastic Large Cell Lymphoma, ALK-Negative | Peripheral T-cell Lymphoma NOS | Hepatosplenic Gamma/ Delta T-cell Lymphoma

United Kingdom
Oxford University Hospitals NHS Trust
Cancer Research UK

Completed

Effect of Metformin on Breast Cancer Metabolism

Breast Cancer

United Kingdom
University of Oxford
Norwegian Institute of Public Health; Wellcome Trust

Completed

MenPF-1 - A New Vaccine Against Meningococcal Disease

Serogroup B Meningococcal Disease

United Kingdom
Royal Marsden NHS Foundation Trust
Wellcome Trust; Institute of Cancer Research, United Kingdom; Biomedical Research...

Completed

A Phase I, First in Man Study to Evaluate the Safety and Tolerability of a panRAF Inhibitor (CCT3833/BAL3833)in Patients With Solid Tumours (PanRAF)

Melanoma | Cancer

United Kingdom
University of Oxford
Sanaria Inc.; KEMRI-Wellcome Trust Collaborative Research Program; University... and other collaborators

Unknown

Controlled Human Malaria Infection in Semi-Immune Kenyan Adults. (CHMI-SIKA) (CHMI-SIKA)

Malaria

Kenya
The Christie NHS Foundation Trust
AstraZeneca; Cancer Research UK

Terminated

Dual REctcal Angiogenesis or MEK Inhibition radioTHERAPY Trial (DREAMtherapy)

Rectal Cancer

United Kingdom
University Hospital Birmingham NHS Foundation Trust
Pancreatic Cancer UK

Recruiting

The Development of a Metabolomic Test to Diagnose and Quantify Pancreatic Exocrine Insufficiency (The DETECTION Study) (DETECTION)

Pancreatic Exocrine Insufficiency

United Kingdom
The Leeds Teaching Hospitals NHS Trust
Cancer Research UK

Recruiting

Experiences and Perceptions of Colonoscopy and New Technologies

Bowel Cancer | Colonoscopy

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Cancer Research UK

Completed

A Feasibility Study for a Multicentre Randomised Controlled Trial to Compare Surgery With Needle Ablation Techniques in People With Small Renal Masses (4cm) (CONSERVE)

Renal Cancer

United Kingdom
The Leeds Teaching Hospitals NHS Trust
Cancer Research UK

Completed

Hepatitis C Rimantadine and Antiviral Combination Therapy (HepRiACT)

Hepatitis C

United Kingdom
The Christie NHS Foundation Trust
AstraZeneca; Cancer Research UK

Unknown

Radiotherapy & Olaparib in COmbination for Carcinoma of the Oesophagus (ROCOCO)

Carcinoma of the Oesophagus

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
AstraZeneca; Cancer Research UK Cambridge Institute

Recruiting

DLBCL Interim Response Evaluation for Customised Therapy (DIRECT)

High-grade B-cell Lymphoma

United Kingdom
Barts & The London NHS Trust
Cancer Research UK; Amgen

Unknown

Comparison Study of Standard Care Against Combination of Growth Factors Agents for Low-risk Myelodysplastic Syndromes (REGIME)

Myelodysplastic Syndrome

United Kingdom
Nottingham University Hospitals NHS Trust
Wellcome Trust; National Institute for Health Research, United Kingdom

Unknown

The Use of Interactive Binocular Treatment (I-BiT) for the Management of Anisometropic, Strabismic and Mixed Amblyopia in Children Aged 3.5 - 12 Years (I-BiT Plus)

Strabismus | Amblyopia
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Cancer Research UK

Recruiting

UK Genetic Prostate Cancer Study: Epidemiology and Molecular Genetics Studies (UKGPCS)

Prostate Cancer

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Cancer Research UK

Completed

Preoperative Imaging in Retroperitoneal Sarcoma (PIRS)

Cancer

United Kingdom
Cancer Research UK

Unknown

Study of Blood and Tissue Samples From Patients Receiving Androgen Deprivation for Newly Diagnosed Prostate Cancer

Prostate Cancer

United Kingdom
Cancer Research UK

Unknown

Study of Genes and the Environment in Patients With Ovarian Cancer in the East Anglia, Oxford, Trent, or West Midlands Regions of the United Kingdom

Ovarian Cancer

United Kingdom
Cancer Research UK

Unknown

Study of Genes and the Environment in Patients With Colorectal Cancer in the East Anglia Region of the United Kingdom

Colorectal Cancer

United Kingdom
Cancer Research UK

Unknown

Study of Genes and the Environment in Patients With Endometrial Cancer in the East Anglia, Oxford, Trent, or West Midlands Regions of the United Kingdom

Endometrial Cancer

United Kingdom
Cancer Research UK

Unknown

Combination Chemotherapy and Rituximab in Treating Patients With Diffuse Large B-Cell Non-Hodgkin Lymphoma

Lymphoma

United Kingdom
Cancer Research UK

Completed

Capecitabine and Oxaliplatin or Standard Follow-Up Care in Treating Patients Who Have Undergone Surgery for Locally Advanced Rectal Cancer

Colorectal Cancer

United Kingdom
Cancer Research UK

Unknown

Study of Blood and Tissue Samples From Patients With Stomach Cancer, Esophageal Cancer, or Gastroesophageal Junction Cancer

Gastric Cancer | Esophageal Cancer | Adenocarcinoma of the Gastroesophageal Junction

United Kingdom
Cancer Research UK

Unknown

Carmustine, Etoposide, Cytarabine, Melphalan, and Alemtuzumab Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

Lymphoma
Cancer Research UK

Completed

Combination Chemotherapy With or Without Rituximab in Treating Patients With Previously Treated Chronic Lymphocytic Leukemia

Leukemia

United Kingdom
Cancer Research UK

Unknown

Donor Stem Cell Transplant in Treating Patients With Mantle Cell Lymphoma

Lymphoma
Cancer Research UK

Completed

Radiation Therapy With or Without Chemotherapy in Treating Patients With Advanced Head and Neck Cancer

Head and Neck Cancer

United Kingdom, India
Cancer Research UK

Completed

Bryostatin 1 In Treating Patients With Progressive Kidney Cancer

Kidney Cancer

United Kingdom
Cancer Research UK

Completed

Gemcitabine With or Without Capecitabine in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

Pancreatic Cancer

United Kingdom
Cancer Research UK

Unknown

Blood Samples From Healthy Volunteers for Genetic Studies in the East Anglia Region of the United Kingdom

Healthy, no Evidence of Disease

United Kingdom
Cancer Research UK

Unknown

High-Dose Chemotherapy Given Together With Peripheral Blood Stem Cell Transplant in Treating Patients With Intestinal T-Cell Lymphoma

Lymphoma | Small Intestine Cancer

United Kingdom
Cancer Research UK

Unknown

Study of Genes and the Environment in Patients With Prostate Cancer Residing in the East Anglia, Trent, or West Midlands Regions of the United Kingdom

Prostate Cancer

United Kingdom
Cancer Research UK

Unknown

Study of Genes and Environment in Patients With Cancer in East Anglia, Trent, or West Midlands Regions of the United Kingdom

Lymphoma | Kidney Cancer | Pancreatic Cancer | Esophageal Cancer | Brain and Central Nervous System Tumors | Bladder Cancer | Intraocular Melanoma | Melanoma (Skin) | Transitional Cell Cancer of the Renal Pelvis and Ureter

United Kingdom
Cancer Research UK

Unknown

Study of Genes and Environment in Patients With Breast Cancer in the East Anglia Region of the United Kingdom

Breast Cancer

United Kingdom
Cancer Research UK

Unknown

Alemtuzumab and Combination Chemotherapy in Treating Patients With Stage I, Stage II, Stage III, or Stage IV Peripheral T-Cell Lymphoma

Lymphoma | Small Intestine Cancer

United Kingdom
Cancer Research UK

Unknown

Adjuvant Hormone Therapy in Treating Women With Operable Breast Cancer

Breast Cancer

United Kingdom, Belgium
Cancer Research UK

Unknown

Fludarabine Phosphate, Melphalan, and Alemtuzumab Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed Hodgkin Lymphoma

Lymphoma
Cancer Research UK

Terminated

Carboplatin With or Without Decitabine in Treating Patients With Progressive, Advanced Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cavity Cancer

United Kingdom
Cancer Research UK

Terminated

Exemestane With or Without ATN-224 in Treating Postmenopausal Women With Recurrent or Advanced Breast Cancer

Breast Cancer

United Kingdom
Cancer Research UK

Completed

Single-Dose Local Radiation Therapy Compared With Ibandronate in Treating Patients With Localized Metastatic Bone Pain

Pain | Prostate Cancer | Metastatic Cancer

United Kingdom

Clinical Trials Sponsored by Wellcome Trust Sanger Institute, UK

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