Clinical Trials Sponsored by Wellcome Trust

Total 6204 results

Kineta Inc.
Wellcome Trust

Completed

Multiple Ascending Oral Dose 14-Day Trial of LHF-535 in Healthy Participants

Healthy

Australia
GE Healthcare
Wellcome Trust

Terminated

Development of a MR Scanner Capable of Being Sited in a Neonatal Intensive Care Unit (Firefly)

Image Evaluation

United States
GE Healthcare
Wellcome Trust

Completed

Development of a MR Scanner Capable of Being Sited in a Neonatal Intensive Care Unit (Firefly Sheffield)

Neonatal Neuroimaging

United Kingdom
Summit Therapeutics
Wellcome Trust

Completed

A Study of SMT19969 Compared With Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhoea (CDAD)

Clostridium Difficile Infection

United States, Canada
University of Oxford
Wellcome Trust

Recruiting

A Controlled Human Vivax Malaria Infection Study Through Inoculation of Infected Erythrocytes (MIST2)

Plasmodium Vivax Infection

Thailand
Imperial College London
Wellcome Trust

Recruiting

Additional Treatments to the Local Tumour for Metastatic Prostate Cancer: Assessment of Novel Treatment Algorithms (IP2-ATLANTA)

Prostate Cancer | Metastatic Prostate Cancer

United Kingdom
University of Oxford
Wellcome Trust

Completed

Complement 2: Blood Donations to Develop Vaccines Against Infectious Diseases (C2)

Complement Mediated Bacterial Killing in Healthy Adults

United Kingdom
University of Exeter
Wellcome Trust

Completed

Forearm Immobilization, Metabolic Health, and Nutrition

Healthy

United Kingdom
Imperial College London
Wellcome Trust

Completed

Guanfacine for the Treatment of Spatial Neglect and Impaired Vigilance (GASNIV)

Stroke | Hemispatial Neglect

United Kingdom
Queen's University, Belfast
Wellcome Trust

Completed

Tailored Mediterranean Lifestyle Education in Patients With Mild Cognitive Impairment

Mild Cognitive Impairment

United Kingdom
University of KwaZulu
Wellcome Trust

Completed

Vertical Transmission Study (VTS)

HIV

South Africa
Johns Hopkins University
Wellcome Trust

Completed

Effect of Intensive Fly Control on Trachoma and Ocular Chlamydia Infection in Tanzania

Trachoma

United States
University of Oxford
Wellcome Trust

Unknown

Neonatal Sepsis and GBS Carriage Study (NSS)

Neonatal Sepsis | Maternal GBS Carriage

Thailand
Nottingham University Hospitals NHS Trust
Wellcome Trust

Completed

I-BiT - Evaluation of a Novel Binocular Treatment System (I-BiTTM) in Children With Amblyopia (I-BiT)

Amblyopia

United Kingdom
University of Oxford
Wellcome Trust

Recruiting

Mechanisms of Neurodynamic Treatments (MONET)

Carpal Tunnel Syndrome | Physiotherapy | Neurodynamic Treatment | Nerve Mobilisation | Diffusion MRI | Mechanistic Trial

United Kingdom
Queen's University, Belfast
Wellcome Trust

Completed

Tailored Mediterranean Lifestyle Education in Participants With Subjective Cognitive Impairment

Subjective Cognitive Impairment

United Kingdom
University of Oxford
Wellcome Trust

Completed

Oxford Haemodynamic Adaptation to Reduce Pulsatility Trial (OxHARP)

Small Vessel Cerebrovascular Disease

United Kingdom
University of Exeter
Wellcome Trust

Completed

Forearm Immobilization, Metabolic Health, and Muscle Loss

Healthy

United Kingdom
University College, London
Wellcome Trust

Unknown

A Phase I Clinical Trial of DARC

Ocular Hypertension | Glaucoma | Glaucoma, Suspect

United Kingdom
Imperial College London
Wellcome Trust

Completed

The Development of a Human Model of Respiratory Syncytial Virus Infection

Respiratory Syncytial Virus Infections | Respiratory Viral Infections

United Kingdom
University of Oxford
Wellcome Trust

Completed

A Study to Assess the Safety and Immunogenicity of a New Influenza Vaccine Candidate MVA-NP+M1 in Healthy Adults

Influenza

United Kingdom
University College, London
Wellcome Trust

Unknown

Differential Effects of Lipids on Cardiovascular Diseases: A CALIBER Study

ST Elevation Myocardial Infarction | Stable Angina | Unstable Angina | Non ST Elevation Myocardial Infarction | Myocardial Infarction Not Otherwise Specified

United Kingdom
University of Oxford
Wellcome Trust

Completed

A Study to Assess the Safety and Efficacy of a New Influenza Candidate Vaccine MVA-NP+M1 In Healthy Adults

Influenza

United Kingdom
University of Oxford
Wellcome Trust

Unknown

Immediate Versus Deferred Antiretroviral Therapy for HIV-Associated Tuberculous Meningitis

HIV Infections | Tuberculous Meningitis

Vietnam
Aga Khan University
Wellcome Trust

Unknown

Comparison of Screening Tools for Coronary Artery Disease

Cardiovascular Disease

Pakistan
University of Oxford
Wellcome Trust

Recruiting

Simvastatin and Emotional Processing (OxSTEP) (OxSTEP)

Depression | Inflammation

United Kingdom
University of Oxford
Wellcome Trust

Terminated

Neurofeedback for Stroke Rehabilitation

Stroke

United Kingdom
Novartis Pharmaceuticals
Wellcome Trust

Completed

Study to Assess Safety, Tolerability and Phamacokinetics of KAE609 Administered Intravenously in Healthy Subjects

Malaria

Belgium
University of Oxford
Wellcome Trust

Completed

7-day Atorvastatin and Emotional Processing

Healthy

United Kingdom
University of Oxford
Wellcome Trust

Completed

The Clinical and Molecular Epidemiology of Streptococcus Agalactiae Colonisation on the Kenyan Coast (GBS)

Streptococcus Agalactiae (Streptococcus Group B)

Kenya
University of Oxford
Wellcome Trust

Completed

The Study of Chest Infections in Infants Living in a Refugee Camp on the Thai-Burmese Border (ARI)

Childhood Pneumonia | Pneumococcal Carriage

Thailand
University of Reading
Wellcome Trust

Completed

Study Into Genetic Influence on Cholesterol Response to Dietary Fat (Satgene)

Cardiovascular Diseases

United Kingdom
Medical Research Council
Wellcome Trust

Unknown

Evaluation of the Efficacy of Hydroxychloroquine in Decreasing Immune Activation in Asymptomatic HIV-infected Patients (HCQ-01)

HIV Infections
Aga Khan University
Wellcome Trust

Unknown

Effects of Low Salt Diet Versus High Salt Diet on Blood Pressure

Hypertension

Pakistan
Sheffield Teaching Hospitals NHS Foundation Trust
Wellcome Trust

Completed

Virtual Coronary Physiology: an Angiogram is All You Need

Coronary Artery Disease

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Wellcome Trust

Unknown

Mitochondrial Donation: An 18 Month Outcome Study.

Mitochondrial Diseases

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Wellcome Trust

Completed

Biomarker-based Exclusion of VAP for Improved Antibiotic Stewardship (VAPRapid-2)

Ventilator-associated Pneumonia

United Kingdom
KEMRI-Wellcome Trust Collaborative Research Program

Completed

Dynamics of the Immune Response in Children to the 23-valent Pneumococcal Capsular Polysaccharide Vaccine (Pneumovax)

Pneumonia, Pneumococcal

Kenya
Federal University of Pelotas
Wellcome Trust

Completed

The 2015 Pelotas (Brazil) Birth Cohort Study

Physical Activity | Preterm Birth | Pregnancy Related | Breast Feeding | Mother-Child Relations | Infant Development | Medicine, Narrative

Brazil
KEMRI-Wellcome Trust Collaborative Research Program

Completed

Effect of Enhanced Feedback to Hospitals in an Emerging Clinical Information Network

Pneumonia

Kenya
Sangath
Wellcome Trust DBT India Alliance

Completed

The Preliminary Evaluation of Supporting Addiction Affected Families Effectively

Addiction

India
University of Leicester
Wellcome Trust; Medtronic

Completed

Rowing Away From Diabetes

Hyperglycemia | Diabetes Mellitus, Type 2 | Glucose Intolerance

United Kingdom
St George's, University of London
Wellcome Trust; Rosetrees Trust

Unknown

Early Biomarkers for ARthritic PAIN to Guide Improved Treatments for Arthritis (ARPAIN)

Rheumatoid Arthritis | Osteoarthritis, Knee | Psoriatic Arthritis | Spondyloarthritis

United Kingdom
University of Edinburgh
Wellcome Trust; Simbec Research

Completed

A Phase I Study of Oral UE2343 in Healthy Subjects (UE2343)

Healthy

United Kingdom
KEMRI-Wellcome Trust Collaborative Research Program
GlaxoSmithKline

Unknown

An Extended Follow up of a RTS,S/AS01E Malaria Vaccine Trial (MAL059)

Malaria

Kenya
Imperial College London
Wellcome Trust; Imperial College Healthcare NHS Trust

Terminated

Safety, Tolerability and Efficacy Study of PP1420 in HV (PP14201b1c)

Obesity

United Kingdom
Imperial College London
Wellcome Trust; Imperial College Healthcare NHS Trust

Completed

A First-Time-in-Human Study to Assess the Safety and Tolerability of PP 1420 in Healthy Subjects

Obesity

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Wellcome Trust; Newcastle University

Completed

Biomarkers of Remission in Rheumatoid Arthritis (BioRRA) (BioRRA)

Rheumatoid Arthritis

United Kingdom
University of California, Los Angeles
Wellcome Trust

Enrolling by invitation

Investigating LIFUP in Anhedonic Depression (ILIAD)

Depression | Anhedonia

United States
University of Dundee
Wellcome Trust; Diabetes UK

Completed

Genetics of Diabetes Audit and Research in Tayside Scotland (DOLORisk Dundee) (GoDARTS)

Diabetic Neuropathic Pain

United Kingdom

Clinical Trials Sponsored by Wellcome Trust

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