Clinical Trials Sponsored by York Trials Unit

Total 281 results

Scottish Clinical Trials Research Unit
Pfizer

Completed

Study of Axitinib for Reducing Extent of Venous Tumour Thrombus in Renal Cancer With Venous Invasion (NAXIVA)

Renal Cell Carcinoma | Metastatic Renal Cell Carcinoma | Non-metastatic Renal Cell Carcinoma

United Kingdom
University of Plymouth
Peninsula Clinical Trials Unit

Recruiting

Anti-psychotic Drug Prescribing Patterns Within Specialist Adult ID Services in England and Wales (APHID)

Intellectual Disability

United Kingdom
Wales Cancer Trials Unit
Pierre Fabre Laboratories

Completed

Vinorelbine in Mesothelioma (VIM)

Mesothelioma

United Kingdom
Wales Cancer Trials Unit
Velindre NHS Trust

Unknown

Ibandronate or Zoledronate in Treating Patients With Newly Diagnosed Bone Metastases From Breast Cancer

Breast Cancer | Metastatic Cancer | Hypercalcemia of Malignancy

United Kingdom
University of Manchester
Clinical Trials Unit, Manchester

Recruiting

Trial of a Ward-Based Intervention to Improve Access to Psychologically-Informed Care and Psychological Therapy for Mental Health In-Patients (TULIPS)

Mental Health

United Kingdom
Wales Cancer Trials Unit
Cancer Research UK

Unknown

Cisplatin, Capecitabine, and Radiation Therapy With or Without Cetuximab in Treating Patients With Esophageal Cancer

Esophageal Cancer

United Kingdom
Nordic Society of Gynaecological Oncology - Clinical...

Recruiting

Characterization of Epithelial Ovarian Cancer Patients in Terms of Homologous Recombination Phenotype (HERO)

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer

Denmark
Nordic Society of Gynaecological Oncology - Clinical...

Withdrawn

Trial Comparing Niraparib-bevacizumab-Dostarlimab and Niraparib-bevacizumab to Standard of Care in Recurrent Ovarian Cancer

Ovarian Cancer

Norway, Denmark, Finland
Nordic Society of Gynaecological Oncology - Clinical...

Completed

Chemotherapy vs Hormonal Treatment in Platinum-resistant Ovarian Cancer Resistant or Refractory to Platinum and Taxane

Ovarian Cancer | Peritoneal Cancer | Cancer of the Fallopian Tube
Nordic Society of Gynaecological Oncology - Clinical...

Completed

A Phase II Study of Docetaxel and Carboplatin in Late Relapse of Ovarian Cancer

Ovarian Epithelial Cancer Recurrent

Denmark, Finland, Norway
Wales Cancer Trials Unit

Unknown

Standard Medical Care or Urgent Chest X-ray in Diagnosing Lung Cancer in Smokers With Chest Symptoms Who Are Older Than 60 Years

Tobacco Use Disorder | Lung Cancer
Wales Cancer Trials Unit

Unknown

Standard Surgery or Minimal-Access Surgery in Treating Patients With Bladder Cancer

Bladder Cancer

United Kingdom
Nordic Society of Gynaecological Oncology - Clinical...

Completed

Exemestane in Advanced and Recurrent Endometrial Carcinoma

Endometrial Cancer

Norway
Wales Cancer Trials Unit

Unknown

First-Line Chemotherapy With or Without Neuromuscular Electrical Stimulation in Treating Patients With Non-Small Cell Lung Cancer

Fatigue | Lung Cancer | Chemotherapeutic Agent Toxicity | Musculoskeletal Complications

United Kingdom
Oxford University Hospitals NHS Trust
Surgical Intervention Trials Unit (trial oversight); NIHR Direct Delivery Team... and other collaborators

Recruiting

HIFU Ablation of Soft Tissue Sarcoma (SarcAblate)

Soft Tissue Sarcoma | Desmoid; Abdominal

United Kingdom
Cancer Clinical Trials Unit, Scotland

Completed

MRI in Predicting Early Response to Chemotherapy in Patients With Locally Advanced Breast Cancer

Breast Cancer

United Kingdom
The Christie NHS Foundation Trust
Clinical Trials Unit, Manchester

Completed

Multi-maintenance Olaparib After Disease Recurrence in Participants With Platinum Sensitive BRCAm High Grade Serous Ovarian Cancer (MOLTO)

Ovarian Cancer

United Kingdom
Jochen Roessler
Clinical Trials Unit Freiburg

Withdrawn

Open Label Study of Everolimus (RAD001) in Patients With Segmental Overgrowth Syndrome (EPASOS)

Segmental Overgrowth Syndrome

Germany
Copenhagen Trial Unit, Center for Clinical Intervention...

Not yet recruiting

Safeguarding the Brain of Our Smallest Children-IIIv (SafeBoosC-IIIv) (SafeBoosC-IIIv)

Infant, Newborn, Diseases | Hypoxia
Imperial College London
Wellcome Trust; Imperial Clinical Trials Unit (ICTU)

Completed

PROState Pathway Embedded Comparative Trial (IP3-PROSPECT)

Prostate Cancer | Metastatic Prostate Cancer | Prostate Adenocarcinoma | Prostate Cancer Metastatic | Metastatic Prostate Carcinoma in the Soft Tissue | Non-metastatic Prostate Cancer

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Kings Clinical Trials Unit

Completed

Muscle Stimulation in Advanced Idiopathic Pulmonary Fibrosis (MUST-IPF)

Idiopathic Pulmonary Fibrosis

United Kingdom
Queen's University, Belfast
Innovate UK; Northern Ireland Clinical Trials Unit

Active, not recruiting

Clinical Evaluation of a Point of Care (POC) Assay to Identify Phenotypes in the Acute Respiratory Distress Syndrome (PHIND)

Acute Respiratory Distress Syndrome (ARDS)

United Kingdom, Ireland
Sofia Perea, Director Clinical Trials Unit.

Unknown

Chemotherapy Selection Based on Therapeutic Targets for Advanced Pancreatic Cancer

Carcinoma, Pancreatic Ductal

Spain
Imperial College London
University of Oxford; Clinical Trial Service Unit and Epidemiological Studies...

Completed

An Observational Study of Natural History of Cardiovascular Diseases

Cardiovascular Diseases | Stroke | TIA | Heart Attack

United Kingdom
Cancer Trials Ireland
University College Cork

Active, not recruiting

Dose Escalation Study of Lithium With Oxaliplatin and Capecitabine in Advanced Oesophago-Gastric or Colorectal Cancer (Lithium)

Colorectal Neoplasms | Esophageal Neoplasms | Stomach Neoplasm

Ireland
Kancera AB
Nordic Society of Gynaecological Oncology - Clinical Trials Unit

Recruiting

A Study to Evaluate the Safety of KAND567, in Combination With Carboplatin Therapy, in Women With Recurrent Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (KANDOVA)

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Peritoneal Cancer

Denmark, Norway, Sweden
Sofia Perea, Director Clinical Trials Unit.

Unknown

RAS Switch in Patients With Metastatic RAS Native Colorectal Tumors Treated With 1st Line FOLFIRI-Cetuximab (BEAMING)

Colorectal Cancer Metastatic

Spain
Hull University Teaching Hospitals NHS Trust
National Institute for Health Research, United Kingdom; University of York; South... and other collaborators

Completed

Feasibility Study of Early Review and Early Cardiac Rehabilitation After Coronary Artery Bypass (FARSTER-I)

Coronary Artery Disease | Quality of Life

United Kingdom
Scandinavian Critical Care Trials Group
Rigshospitalet, Denmark; University of Copenhagen; Copenhagen Trial Unit, Center...

Completed

Transfusion-requirements in Septic Shock Trial (TRISS)

Septic Shock

Sweden, Norway, Finland, Denmark
Medela AG
Clinical Trial Unit, University Hospital Basel, Switzerland

Completed

Influence of the Brownie Breast Shield on the Dynamics of Milk Removal (BDM)

Lactation

Switzerland
Cancer Trials Ireland
Southampton Clinical Trials Unit; Region H Rigshospitalet; Centre Hospitalier...

Completed

NEOadjuvant Trial in Adenocarcinoma of the oEsophagus and oesophagoGastric Junction International Study (Neo-AEGIS)

Oesophageal Cancer | Adenocarcinoma of the Oesophagus | Adenocarcinoma of the Oesophago-gastric Junction | Oesophageal Tumours | Junctional Tumours

Ireland, United Kingdom, Denmark, France, Sweden
Belfast Health and Social Care Trust
Northern Ireland Clinical Trials Unit

Completed

A Comparison of Standard Laser With Micropulse Laser for the Treatment of Diabetic Macular Oedema. (DIAMONDS)

Diabetic Macular Edema

United Kingdom
University Hospital Southampton NHS Foundation...
Warwick University Clinical Trials Unit

Not yet recruiting

Ventricular Fibrillation Following Out-of-hospital Cardiac Arrest

Ventricular Fibrillation | Cardiac Arrest, Out-Of-Hospital

United Kingdom
Imperial College London
Prostate Cancer UK; Imperial Clinical Trials Unit (ICTU)

Recruiting

Comparative Health Research Outcomes of NOvel Surgery in Prostate Cancer (IP4-CHRONOS)

Prostate Cancer | Prostate Adenocarcinoma | Non-metastatic Prostate Cancer

United Kingdom
Unity Health Toronto
CIHR Canadian HIV Trials Network

Completed

Bone Antiresorptive Therapy With Antiretroviral Initiation (BATARI) Pilot Trial (BATARI)

HIV

Canada
Sofia Perea, Director Clinical Trials Unit.
Novartis

Completed

Pharmacodynamic Study of BKM120 in Breast Cancer

Breast Cancer

Spain
Naestved Hospital
Copenhagen Trial Unit, Center for Clinical Intervention Research; Research...

Completed

The Transfusion Triggers in Vascular Surgery Trial (TV)

Arterial Occlusive Diseases | Atherosclerosis | Anemia | Aortic Aneurysm, Abdominal

Denmark
Dr. Morten Hylander Møller
Rigshospitalet, Denmark; Copenhagen Trial Unit, Center for Clinical Intervention...

Completed

Stress Ulcer Prophylaxis in the Intensive Care Unit (SUP-ICU)

Gastrointestinal Bleeding | Stress Ulcers

Denmark, Netherlands, Switzerland, Norway, Finland, United Kingdom
Ente Ospedaliero Cantonale, Bellinzona
Clinical Trial Unit Ente Ospedaliero Cantonale

Recruiting

A Study to Compare Two Techniques for the Reconstruction of the Anterior Cruciate Ligament (ACL)

Complete Tear, Knee, Anterior Cruciate Ligament

Italy, Switzerland
Cantonal Hosptal, Baselland
Clinical Trial Unit, University Hospital Basel, Switzerland

Withdrawn

Iron Substitution With Ferric Carboxymaltose as Treatment Strategy for Heart Failure Patients With Preserved Ejection Fraction (IRON-HFpEF)

Iron-deficiency | Heart Failure With Normal Ejection Fraction
Naestved Hospital
Copenhagen Trial Unit, Center for Clinical Intervention Research

Completed

Effect of Dexamethasone as Analgesic Treatment After Total Knee Arthroplasty

Postoperative Pain

Denmark
Copenhagen Trial Unit, Center for Clinical Intervention...
Bispebjerg Hospital

Completed

Eccentric Exercise in Treatment of Achilles Tendinopathy

Achillodynia

Denmark
Insel Gruppe AG, University Hospital Bern
Clinical Trials Unit University of Bern

Not yet recruiting

Closed Incision Negative Pressure Wound Therapy for the Prevention of Surgical Site Infections in Abdominal Surgery (CISSI)

Surgical Wound Infection

Switzerland
Copenhagen Trial Unit, Center for Clinical Intervention...
Bispebjerg Hospital

Completed

KATHY:Cognitive-behavioural Therapy for Hypochondriasis

Hypochondriasis
Rigshospitalet, Denmark
Copenhagen Trial Unit, Center for Clinical Intervention Research

Unknown

The FEEDBACK Trial, a Randomized Controlled Trial (Feedback)

Laparoscopic Proficiency

Denmark
IGLESIAS Juan Fernando
Clinical Trials Unit University of Bern

Not yet recruiting

STEMI Treated With a Polymer-free Sirolimus-coated Stent and P2Y12 Inhibitor-based SAPT Versus Conventional DAPT (STARS DAPT)

ST Elevation Myocardial Infarction

Switzerland
Norfolk and Norwich University Hospitals NHS Foundation...
Norwich Clinical Trials Unit

Recruiting

Treating People With Idiopathic Pulmonary Fibrosis With the Addition of Lansoprazole (TIPAL)

Idiopathic Pulmonary Fibrosis

United Kingdom
Prof. Dr. Nikolas von Bubnoff
Clinical Trials Unit Freiburg

Terminated

Ruxolitinib In GvHD (RIG)

Graft vs Host Disease

Germany
Rigshospitalet, Denmark
Copenhagen Trial Unit, Center for Clinical Intervention Research

Recruiting

The Anesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury (KETA-BID)

Traumatic Brain Injury | Subarachnoid Hemorrhage, Aneurysmal | Intracerebral Hemorrhage

Denmark
University of Basel
Clinical Trial Unit, University Hospital Basel, Switzerland

Recruiting

High-intensity Interval Training in Heart Failure Patients With Preserved Ejection Fraction (HIT-HF)

Heart Failure With Normal Ejection Fraction

Switzerland

Clinical Trials Sponsored by York Trials Unit

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