Clinical Trials Sponsored by Zhang Lei

Total 7388 results

Lai Wei

Active, not recruiting

Safety and Efficacy of Celecoxib Plus Nucleos(t)Ide Analogues on the Hepatitis B Surface Antigen of Virally Suppressed Subjects With Chronic Hepatitis B

To Evaluate the Safety and Efficacy of Celecoxib Plus Nucleos(t)Ide Analogues in Nucleos(t)Ide-treated Patients With Chronic Hepatitis B

China
Lai Wei

Not yet recruiting

Registry-based Study in Patients With Hepatitis D Virus (HDV) Infection in China

Hepatitis D

China
Wei Zhang

Recruiting

Efficacy and Safety of Regorafenib Maintenance Therapy in Patients With Metastatic Colorectal Cancer (mCRC)

Colorectal Cancer

China
Mei Zhang

Active, not recruiting

Follow up Study of Crocin on Cardiac Function Protection in Patients With Breast Cancer Undergoing Neoadjuvant Chemotherapy Based on Color Doppler Ultrasound Combined With Myocardial Zymogram

Breast Cancer

China
Mei Zhang

Recruiting

Neoadjuvant Effect of Albumin Binding Paclitaxel Compared With Common Paclitaxel in Breast Cancer：an Observational Single Center Study of Clinical Efficacy in Adjuvant Chemotherapy

Breast Cancer

China
Zhang Lei

Recruiting

Evaluation of Immune Status Before and After Splenectomy in Immune Thrombocytopenia Patients

Thrombocytopenia | Splenectomy

China
Zhang Lei

Recruiting

A Prospective, One-arm and Open Clinical Study of Zanubrutinib in the Treatment of Immune Thrombocytopenia

Immune Thrombocytopenia | Treatment

China
Li Zhang

Recruiting

Cardenilimab Combined With Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma | Neoadjuvant Therapies

China
Zhang Lei, MD

Recruiting

Safety and Efficacy of Zanubrutinib in the Treatment of Antiphospholipid Syndrome With Secondary Thrombocytopenia

Thrombocytopenia | Antiphospholipid Syndrome | Treatment

China
Li Zhang

Unknown

Evaluate Erlotinib Efficacy and Safety as the 2nd/3rd Treatment in NSCLC With EGFR M(-) and C-met(-)

Non-small Cell Lung Cancer

China
Li Zhang

Unknown

Effects of Whole-body Vibration in the Frail Elderly

Osteoporosis | Sarcopenia;

China
Li Zheng

Not yet recruiting

Selinexor in Combination With Thalidomide and Dexamethasone in RRMM

Multiple Myeloma

China
Chang Wei-Jung

Completed

Outcome After Laparoscopic Surgery for Peptic Ulcer Perforation

Pneumonia | Intraabdominal Abscess After Procedure | Leakage | Operation Wound; Infection
Li Zhang, MD

Not yet recruiting

Phase III Study Comparing Osimertinib Monotherapy to Combination Therapy With Osimertinib,Carboplatin and Pemetrexed for Untreated Patients With Advanced Non-squamous Non-Small Cell Lung Cancer With Concurrent EGFR and TP53 Mutations (TOP)

Non-small Cell Carcinoma | EGFR Gene Mutation

China
Zhang Lei

Completed

Hypertension and Controlled Hypotension in the Elderly

Delirium

China
Li Zhang
Hubei Cancer Hospital

Not yet recruiting

SBRT Combined With Osimertinib Compared With Osimertinib for Stage IV NSCLC

Stage IV Non-small Cell Lung Cancer

China
Li Zhang, MD

Recruiting

An Open Label, Multicenter Phase 2 Study of Durvalumab (MEDI4736) + Olaparib as Maintenance Therapy in Chinese

Small Cell Lung Cancer | Lung Cancer | Durvalumab

China
Li Zhang, MD

Recruiting

Ensatinib Treat Second-generation ALK-TKI Resistance After Second-generation ALK-TKI Resistance (ERSGATR)

The Diagnosis Was ALK Positive NSCLC | Second Generation ALK-TKI is Resistant | Efficacy of Ensatinib in This Subset of Patients

China
Li Zhang, MD

Recruiting

Surufatinib Combined With Toripalimab and Chemotherapy in the Treatment of Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

China
Li Zhang, MD

Not yet recruiting

JS001 Combination Therapy in NSCLC Negative Driving Gene After First-line Chemotherapy.

Non-small Cell Lung Cancer

China
Mei-Yun Chang

Completed

A Comparison of Optimal PEEP Determination Guided by EIT and G5 Device in Moderate and Severe ARDS Patients

Acute Respiratory Distress Syndrome

Taiwan
Pei-Hsin Yang

Completed

The Effects of Individualized Nutritional Intervention Program in Malnutrition Elderly With Pneumonia

Pneumonia

Taiwan
Shu-Mei Chen

Completed

Elastic Band Resistance Exercise on Glycated Haemoglobin and Muscle Strength, Balance, and Physical Function in Patients With Comorbid Type 2 Diabetes Mellitus and Knee Osteoarthritis

Elastic Band Resistance Exercise With Comorbid Type 2 Diabetes Mellitus and Knee Osteoarthritis

Taiwan
Mei-fang Huang

Unknown

Effectiveness of Health Management of Glycemic Control and Physical Activity in Type 2 Diabetes Mellitus Using Smartphone Application

To Investigate the Effectiveness of Health Management of Glycemic Control and Physical Activity in Type 2 Diabetes Mellitus Using Smartphone Application

Taiwan
Lei Lei, MD

Recruiting

Neurofeedback-Based Digital Therapeutics for the Diagnosis and Treatment of ADHD in Children. (ADHD)

Attention Deficit Disorder With Hyperactivity | Executive Function Disorder

China
Zheng Li

Not yet recruiting

Trajectory of Frailty and Cognitive Dysfunction in Older Adults

Cognitive Dysfunction | Frailty | Community-dwelling Older Adults
Chang Hee, Lee
Purdue University; LG Electronics Inc.

Completed

Effects of Telemonitoring and Telemedicine Service for Hypertensive Care (Smart-HTN)

Hypertension

Korea, Republic of
Lei Li

Recruiting

ctDNA Methylation for Epithelial Ovarian Cancer

Epithelial Ovarian Cancer | Circulating Tumor DNA | CA125 | DNA Methylation | Non-invasive Diagnosis | Human Epididymis Protein 4 | Imaging Evaluation | Survival Prognosis

China
Lei Li

Recruiting

PD-1 Antibody and Radiotherapy for Recurrent Cervical Cancer

Recurrent Cervical Carcinoma | Radiotherapy | Immune Checkpoint Inhibitors | Overall Survival | Anti-programmed Death-1 Antibody | Metastatic Cervical Carcinoma | Persistent Advanced Cervical Carcinoma | Objective Remission Rate | Progression-free Survival | Severe Adverse Events

China
Lei Li

Recruiting

Albumin-bound Paclitaxel and Bevacizumab for Platinum-resistant Recurrent Ovarian Cancer

Recurrent Ovarian Carcinoma | Platinum-resistant Ovarian Cancer | Bevacizumab | Ovarian Carcinoma | Survival Outcomes | Adverse Events | Albumin-bound Paclitaxel

China
Lei Li

Recruiting

Donafenib for Recurrent Cervical Cancer

Chemotherapy | Recurrent Cervical Carcinoma | Survival Outcomes | Targeted Therapy | Adverse Effect | Metastatic Cervical Carcinoma | Persistent Advanced Cervical Carcinoma

China
Lei Li

Recruiting

Chromosomal Instability in Ovarian Cancer

Epithelial Ovarian Cancer | High-grade Serous Ovarian Carcinoma | Survival Outcomes | Overall Survival | Progression-free Survival | Chromosomal Instability | Somatic Copy Number Distortion | Minimal Residual Lesions

China
Lei Li

Recruiting

Combination of Nimotuzumab and Radiotherapy for Recurrent Uterine Cervical Squamous Carcinoma

Recurrent Cervical Carcinoma | Radiotherapy | Objective Response Rate | Overall Survival | Progression-free Survival | Epidermal Growth Factor Receptor | Nimotuzumab

China
Lei Li

Recruiting

Genetic Mutation in Epithelial Ovarian Cancer

Epithelial Ovarian Cancer | Microsatellite Instability | PD-L1 | Nucleotide Variant | Copy Number Variation | Insertion-deletion Variation | Genomic Structural Variation | Total Mutation Burden | PD-1

China
Lei Li

Recruiting

Comprehensive Study on the Quality of Life in Cervical Cancer Patients

Quality of Life | Cervical Cancer | Pelvic Floor Disorders | Survivorship | Overall Survival | Disease-free Survival | Urodynamics | Ovarian Reserve Function | Rectum Dynamics | Sex Dysfunction

China
Lei Li

Recruiting

NAC Followed by RH for the Treatment of LACC

Laparotomy | Laparoscopy | Locally Advanced Cervical Cancer | Neoadjuvant Chemotherapy | Adjuvant Therapy | Concurrent Chemoradiotherapy | Radical Hysterectomy | Objective Response | Systematic Chemotherapy

China
Lei Li

Recruiting

Long-acting G-CSF for Febrile Neutropenia

Febrile Neutropenia | Epithelial Ovarian Cancer | Adverse Event | Cost-effectiveness | Myelosuppression Adult | Colony Stimulating Factors

China
Lei Li

Recruiting

Risk-Reducing Surgeries for Hereditary Ovarian Cancer

Colorectal Neoplasms, Hereditary Nonpolyposis | Hysterectomy | Hereditary Breast and Ovarian Cancer Syndrome | Ovariectomy

China
Lei Li

Completed

A Study on Association Between HR Genes and the HRD Status in Chinese Epithelial Ovarian Cancer

Epithelial Ovarian Cancer | BRCA1 Mutation | BRCA2 Mutation | Homologous Recombination Deficiency | Prognosis | Chinese | Homologous Recombination Genes

China
Lei Li

Unknown

Cell-free DNA Methylation for Endometrial Cancer

Endometrial Cancer | Liquid Biopsy | DNA Methylation | Diagnostic Accuracy | Cervical Cytology | Training Set | Validation Set

China
Lei Li

Unknown

National Survey of the Impact of COVID-19 Pandemics (CMDA-SURVEY2)

Questionnaire | China | National Survey | Obstetrics and Gynecology | Workload | COVID-19 Pandemics

China
Lei Li

Unknown

DNA Methylation for Screening Uterine Cervical Lesions

DNA Methylation | Uterine Cervical Cancer | High Grade Squamous Intraepithelial Lesions | Low Grade Squamous Intraepithelial Lesions

China
Lei Li

Unknown

DNA Methylation for Screening Uterine Cervical Lesions: A Case-control Study

DNA Methylation | Uterine Cervical Cancer | High Grade Squamous Intraepithelial Lesions | Low Grade Squamous Intraepithelial Lesions

China
Lei Li

Unknown

Immune Repertoire of Ovarian HGSC

Ovarian High Grade Serous Carcinoma | Immune Repertoire | T Lymphocyte Receptor | B Lymphocyte Receptor

China
Lei Li

Unknown

Adherence to the Antiemesis National Comprehensive Cancer Network (NCCN) Guideline

Gynecologic Cancer | Chemotherapy-induced Nausea and Vomiting

China
Lei Li

Unknown

A Genomic Analysis of Evolution of Epithelia Ovarian Tumors

Epithelial Ovarian Cancer | Progression-free Survival | Epithelial Ovarian Tumor of Borderline Malignancy | Driving Mutations

China
Lei Li

Unknown

HPV Integration and Tumorigenesis of Uterine Cervical Adenocarcinoma

Cervical Adenocarcinoma | Human Papillomavirus | Metabolome | Prognosis | Whole Exome Sequencing | Tumorigenesis | Transcriptome | Genome-wide Association Study

China
Lei Li

Unknown

Study of Universal Screening for Lynch Syndrome in Chinese Patients of Endometrial Cancer

Colorectal Neoplasms, Hereditary Nonpolyposis | Endometrial Neoplasms

China
Lei Li

Unknown

Functional Training for the Prevention of Deep Venous Thrombosis

Deep Venous Thrombosis | Gynecologic Neoplasm | Ankle Motion | Abdominal Breathing

China
Chang Gung Memorial Hospital
Eli Lilly and Company

Unknown

Radiotherapy With Single-Agent Cisplatin or Combination Chemotherapy in Defined Poor-Prognostic Cervical Cancer

Cervical Cancer

Taiwan

Clinical Trials Sponsored by Zhang Lei

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